Red Sox vs White Sox Prediction, Odds & Player Prop Bets Today – MLB, Apr 12

Chicago White Sox's watches the flight of the ball during a baseball game against the Los Angeles Angels Wednesday, May 31, 2023, in Chicago.
(AP Photo/Charles Rex Arbogast)
  • The Red Sox are -160 favorites vs the White Sox
  • Red Sox vs White Sox Over / Under today: 7.5 Runs
  • Red Sox / White Sox TV Channel: NESN | CHSN

The Boston Red Sox (-160) visit Rate Field to take on the Chicago White Sox (+135) on Saturday, April 12, 2025. First pitch is scheduled for 4:10pm EDT in Chicago, IL.

This season, the Red Sox are 7-8 against the spread (ATS), while the White Sox are 8-5 ATS.

Red Sox vs White Sox Starting Pitchers Today:

  • Red Sox starting pitcher: Richard Fitts 0-2, 4.50 ERA
  • White Sox starting pitcher: Martin Perez 1-0, 0.73 ERA

Red Sox vs. White Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Red Sox-1.5 +105O 7.5 +100-160
White Sox +1.5 -130U 7.5 -120+135

Red Sox vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the Red Sox will win Saturday‘s MLB game with 58.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Red Sox vs White Sox and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Red Sox players for Saturday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Bets Today:

  • Romy Gonzalez has hit the Hits Over in 21 of his last 25 away games (+15.35 Units / 34% ROI)
  • Rafael Devers has hit the Runs Under in 21 of his last 25 away games (+14.20 Units / 39% ROI)
  • Rafael Devers has hit the Total Bases Under in 19 of his last 25 away games (+13.00 Units / 39% ROI)
  • Rafael Devers has hit the RBIs Under in 21 of his last 25 away games (+12.35 Units / 24% ROI)
  • Rafael Devers has hit the Hits Runs and RBIs Under in 19 of his last 25 away games (+12.20 Units / 43% ROI)

And here are some favorite MLB player prop bets for White Sox players for Saturday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

  • Michael A. Taylor has hit the Home Runs Over in 2 of his last 5 games at home (+11.70 Units / 234% ROI)
  • Miguel Vargas has hit the Runs Under in 8 of his last 9 games (+6.50 Units / 31% ROI)
  • Martin Perez has hit the Earned Runs Under in 8 of his last 10 games at home (+6.45 Units / 56% ROI)
  • Andrew Vaughn has hit the Hits Under in his last 4 games (+6.40 Units / 160% ROI)
  • Martin Perez has hit the Hits Allowed Under in 7 of his last 8 games at home (+6.25 Units / 66% ROI)
  • The Boston Red Sox have hit the Team Total Under in their last 5 games (+5.00 Units / 74% ROI)
  • The Boston Red Sox have hit the Game Total Under in 9 of their last 15 games (+3.55 Units / 21% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 5 of their last 10 games (+2.15 Units / 15% ROI)
  • The Boston Red Sox have covered the Run Line in 7 of their last 15 games (+0.25 Units / 1% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 45 of their last 79 games at home (+7.20 Units / 8% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 6 of their last 7 games at home (+4.95 Units / 59% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 4 of their last 7 games at home (+3.95 Units / 55% ROI)
  • The Chicago White Sox have hit the Team Total Under in 5 of their last 6 games (+3.80 Units / 52% ROI)
  • The Chicago White Sox have covered the Run Line in 4 of their last 5 games (+2.90 Units / 45% ROI)

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 7-8 against the Run Line (+0.25 Units / 1.38% ROI).

  • 7-8 when betting on the Moneyline for -3.55 Units / -18.54% ROI
  • 5-9 when betting on the total runs Over for -4.65 Units / -28.53% ROI
  • 9-5 when betting on the total runs Under for +3.55 Units / 21.26% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 8-5 against the Run Line (+2.3 Units / 14.24% ROI).

  • 3-10 when betting on the Moneyline for -5.65 Units / -43.46% ROI
  • 6-6 when betting on the total runs Over for -0.45 Units / -3.2% ROI
  • 6-6 when betting on the total runs Under for -0.75 Units / -5.15% ROI

White Sox vs Red Sox Home Run Prop Bets Today

Over Under
Luis Robert (CWS) 0.5 +475 0.5 -650
Alex Bregman (BOS) 0.5 +500 0.5 -700
Trevor Story (BOS) 0.5 +525 0.5 -750
Rafael Devers (BOS) 0.5 +550 0.5 -800
Kristian Campbell (BOS) 0.5 +550 0.5 -800

White Sox vs Red Sox Total Hits Prop Bets Today

Over Under
Jarren Duran (BOS) 0.5 -275 0.5 +200
Andrew Vaughn (CWS) 0.5 -235 0.5 +175
Alex Bregman (BOS) 0.5 -220 0.5 +165
Luis Robert (CWS) 0.5 -220 0.5 +165
Rob Refsnyder (BOS) 0.5 -200 0.5 +155

White Sox vs Red Sox RBI Prop Bets Today

Over Under
Alex Bregman (BOS) 0.5 +160 0.5 -210
Andrew Vaughn (CWS) 0.5 +170 0.5 -225
Trevor Story (BOS) 0.5 +180 0.5 -235
Kristian Campbell (BOS) 0.5 +190 0.5 -250
Rob Refsnyder (BOS) 0.5 +195 0.5 -275

White Sox vs Red Sox Strikeout Prop Bets Today

Over Under
Martin Perez (CWS) 4.5 -130 4.5 +100
Richard Fitts (BOS) 4.5 +110 4.5 -145

Richard Fitts allowed a batting average of .345 vs right-handed batters (fifth worst)– seventh Percentile and just .125 vs left-handed batters over the last two weeks (tied for eighth best among qualified SPs)– 90th Percentile.

Richard Fitts has allowed a .586 SLG vs right-handed batters (third worst)– fourth Percentile and just .125 vs left-handed batters over the last two weeks (tied for sixth best among qualified SPs)– 93rd Percentile.

Opponents have a swing rate of 54% (28/52) against Richard Fitts on the first pitch of at-bats this season — highest in MLB among starting pitchers with at least 5 total IP; League Avg: 31% — 100th Percentile.

Richard Fitts has thrown breaking pitches 55% of the time (67/122) in non-two strike counts this season — highest in MLB among starting pitchers with at least 5 total IP; League Avg: 27% — 100th Percentile.

White Sox Starting Pitcher Stats & Trends

Right-handed hitters have a chase rate of just 9% (6/66) against Martin Perez this season — lowest in MLB among starting pitchers with at least 5 total IP; League Avg: 30% — 0 Percentile.

Martin Perez has allowed an OPS of 1.063 (134 PA’s) when going through the lineup the third time in a game since last season — highest in MLB among starting pitchers with at least 69 total IP; League Avg: .751 — first Percentile.

Martin Perez allowed a slugging percentage of .699 (79 Total Bases / 113 ABs) when going through the lineup the third time in a game in the 2024 season — highest in MLB among starting pitchers with at least 64 total IP; League Avg: .430 — first Percentile.

Martin Perez allowed an OPS of 1.127 (124 PA’s) when going through the lineup the third time in a game in the 2024 season — highest in MLB among starting pitchers with at least 64 total IP; League Avg: .752 — 0 Percentile.

Red Sox Keys to the Game vs. the White Sox

The Red Sox are just 5-65 (.071) when trailing entering the 7th inning since last season — tied for 2nd lowest in MLB; League Avg: .143.

The Red Sox were just 38-43 (.469) at home in the 2024 season — tied for 5th lowest in MLB; League Avg: .521.

The Red Sox were just 5-58 (.079) when trailing entering the 7th inning in the 2024 season — 3rd lowest in MLB; League Avg: .143.

The Red Sox are just 14-136 (.093) when trailing entering the 7th inning since the 2023 season — 3rd lowest in MLB; League Avg: .141.

White Sox Keys to the Game vs. the Red Sox

The White Sox are just 28-103 (.214) after a loss since last season — lowest in MLB; League Avg: .504.

The White Sox were just 26-95 (.215) after a loss in the 2024 season — lowest in MLB; League Avg: .504.

The White Sox are just 18-69 (.207) on the road since last season — lowest in MLB; League Avg: .472.

The White Sox are just 87-23 (.791) when leading entering the 8th inning since the 2023 season — lowest in MLB; League Avg: .900.

Red Sox hitters struck out 506 times in 1,816 PA’s (28%) against LHP in the 2024 season — highest in MLB; League Avg: 23%.

Red Sox hitters are averaging 4.39 pitches per plate appearance against LHP this season — highest in MLB; League Avg: 3.91.

Red Sox hitters are slugging .428 against RHP since the 2023 season — tied for 3rd best in MLB; League Avg: .406.

The Red Sox batted .182 on pitches out of the zone in 2023 — best in MLB; League Avg: .151.

The White Sox had a winning percentage of just 28% at home last season — lowest in MLB; League Avg: 52%.

White Sox hitters have an OBP of just .283 (9,322 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .315.

White Sox hitters have an OPS of just .644 (9,322 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .721.

The White Sox have a winning percentage of just 34% at home since the 2023 season — lowest in MLB; League Avg: 52%.

Opponents have a miss rate of just 24% against Red Sox pitchers since last season — 2nd lowest in MLB; League Avg: 25%.

Opponents had a miss rate of just 24% against Red Sox pitchers in the 2024 season — tied for 2nd lowest in MLB; League Avg: 25%.

Red Sox pitchers have walked 106 of 1,590 batters (7%) when facing the leadoff batter in the inning since last season — 5th best in MLB; League Avg: 8%.

Opponents have a miss rate of just 25% against Red Sox pitchers since the 2023 season — 5th lowest in MLB; League Avg: 26%.

The White Sox have won just 17% of games in which their opponents scored first since the 2023 season — lowest in MLB; League Avg: 32%.

The White Sox won just 11% of games in which their opponents scored first last season — lowest in MLB; League Avg: 31%.

In games when their opponents scored three or more runs in an inning, the White Sox won just 4% of the time last season — lowest in MLB; League Avg: 24%.

White Sox pitchers walked 643 of 6,241 batters (10%) in the 2024 season — highest in MLB; League Avg: 8%.

More MLB Reading:


Bet now on Red Sox vs White Sox and all games with BetMGM


Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.

Split First Bet Offer FBO March Matchups 1080x610
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.