Reds vs Astros Prediction, Odds & Player Prop Bets Today – MLB, May 11

Houston Astros' Yordan Alvarez runs up the first base line against the Los Angeles Angels during the fourth inning of a baseball game Sunday, June 4, 2023, in Houston.
(AP Photo/David J. Phillip)
  • The Astros are -150 favorites vs the Reds
  • Reds vs Astros Over / Under today: 8.5 Runs
  • Reds / Astros TV Channel: FDOH | SCHN

The Cincinnati Reds (+125) visit Daikin Park to take on the Houston Astros (-150) on Sunday, May 11, 2025. First pitch is scheduled for 2:10pm EDT in Houston, TX.

This season, the Reds are 20-21 against the spread (ATS), while the Astros are 21-17 ATS.

Reds vs Astros Starting Pitchers Today:

  • Reds starting pitcher: Chase Petty 0-1, 34.75 ERA
  • Astros starting pitcher: Ronel Blanco 2-3, 5.08 ERA

Reds vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Reds+1.5 -185O 8.5 -115+125
Astros -1.5 +150U 8.5 -105-150

Reds vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Sunday‘s MLB game with 57.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Reds players for Sunday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Bets Today:

  • Santiago Espinal has hit the Hits Over in 13 of his last 15 games (+10.65 Units / 34% ROI)
  • Gavin Lux has hit the Hits Runs and RBIs Over in 17 of his last 25 away games (+8.65 Units / 29% ROI)
  • Tyler Stephenson has hit the Runs Under in 9 of his last 10 away games (+7.00 Units / 35% ROI)
  • Matt McLain has hit the Total Bases Under in 13 of his last 20 games (+7.00 Units / 28% ROI)
  • Gavin Lux has hit the Singles Over in 11 of his last 15 away games (+6.95 Units / 40% ROI)

And here are some favorite MLB player prop bets for Astros players for Sunday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Victor Caratini has hit the Home Runs Over in 2 of his last 4 games at home (+13.40 Units / 335% ROI)
  • Jeremy Pena has hit the Hits Over in 19 of his last 25 games (+12.75 Units / 26% ROI)
  • Jeremy Pena has hit the Singles Over in 19 of his last 25 games (+11.15 Units / 34% ROI)
  • Isaac Paredes has hit the Total Bases Over in 13 of his last 15 games (+11.00 Units / 46% ROI)
  • Victor Caratini has hit the Runs Over in 7 of his last 10 games (+8.20 Units / 82% ROI)
  • The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 19 of their last 31 games (+6.00 Units / 16% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 16 of their last 30 games (+5.80 Units / 15% ROI)
  • The Cincinnati Reds have hit the Game Total Under in 12 of their last 18 games (+5.10 Units / 25% ROI)
  • The Cincinnati Reds have covered the Run Line in 23 of their last 38 games (+4.55 Units / 8% ROI)
  • The Cincinnati Reds have hit the Moneyline in 10 of their last 18 away games (+3.40 Units / 17% ROI)
  • The Houston Astros have covered the Run Line in 19 of their last 30 games (+10.50 Units / 28% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 12 of their last 15 games at home (+8.55 Units / 45% ROI)
  • The Houston Astros have hit the Team Total Under in 23 of their last 38 games (+7.10 Units / 16% ROI)
  • The Houston Astros have hit the Game Total Over in 9 of their last 12 games (+5.80 Units / 45% ROI)
  • The Houston Astros have hit the Moneyline in 9 of their last 12 games at home (+5.35 Units / 34% ROI)

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 23-18 against the Run Line (+0.2 Units / 0.34% ROI).

  • 20-21 when betting on the Moneyline for -1.95 Units / -3.99% ROI
  • 18-22 when betting on the total runs Over for -6.1 Units / -13.6% ROI
  • 22-18 when betting on the total runs Under for +2.05 Units / 4.52% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 21-17 against the Run Line (+5.85 Units / 12.1% ROI).

  • 19-19 when betting on the Moneyline for -5.25 Units / -10.55% ROI
  • 17-19 when betting on the total runs Over for -3.65 Units / -8.82% ROI
  • 19-17 when betting on the total runs Under for +0.1 Units / 0.24% ROI

Astros vs Reds Home Run Prop Bets Today

Over Under
Christian Walker (HOU) 0.5 +350 0.5 -450
Elly De La Cruz (CIN) 0.5 +425 0.5 -600
Austin Hays (CIN) 0.5 +450 0.5 -625
Zach Dezenzo (HOU) 0.5 +525 0.5 -750
Spencer Steer (CIN) 0.5 +525 0.5 -750

Astros vs Reds Total Hits Prop Bets Today

Over Under
Yainer Diaz (HOU) 0.5 -275 0.5 +200
Jose Altuve (HOU) 0.5 -225 0.5 +170
Elly De La Cruz (CIN) 0.5 -200 0.5 +150
Christian Walker (HOU) 0.5 -200 0.5 +150
Mauricio Dubon (HOU) 0.5 -175 0.5 +135

Astros vs Reds RBI Prop Bets Today

Over Under
Christian Walker (HOU) 0.5 +140 0.5 -185
Austin Hays (CIN) 0.5 +160 0.5 -210
Elly De La Cruz (CIN) 0.5 +165 0.5 -220
Yainer Diaz (HOU) 0.5 +165 0.5 -220
Isaac Paredes (HOU) 0.5 +180 0.5 -250

Astros vs Reds Strikeout Prop Bets Today

Over Under
Chase Petty (CIN) 3.5 -140 3.5 +105
Ronel Blanco (HOU) 6.5 +125 6.5 -160

Chase Petty has limited playing time.

Astros Starting Pitcher Stats & Trends

Ronel Blanco has walked 12% of batters when going through the lineup the first time in a game since last season — highest among qualified SPs in MLB; League Avg: 7% — second Percentile.

Ronel Blanco has walked 12% of batters versus hitters not batting 3-4-5 in the order since last season — highest among qualified SPs in MLB; League Avg: 6% — second Percentile.

Ronel Blanco walked 33 of 270 batters (12%) when going through the lineup the first time in a game in the 2024 season — highest among qualified SPs in MLB; League Avg: 7% — first Percentile.

Opponents batted just .147 (33-for-225) against Ronel Blanco when going through the lineup the second time in a game in the 2024 season — best among qualified SPs in MLB; League Avg: .232 — 100th Percentile.

Reds Keys to the Game vs. the Astros

The Reds are just 14-29 (.326) when tied entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Reds were just 5-16 (.238) when tied entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .500.

The Reds are just 6-77 (.072) when trailing entering the 7th inning since last season — 3rd lowest in MLB; League Avg: .139.

The Reds are just 4-80 (.048) when trailing entering the 8th inning since last season — 2nd lowest in MLB; League Avg: .096.

Astros Keys to the Game vs. the Reds

The Astros are just 1-74 (.013) when trailing entering the 9th inning since last season — 3rd lowest in MLB; League Avg: .049.

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros are just 2-7 (.222) vs top 10 scoring offenses this season They play the Reds (16th best runs scored) today.

The Astros were just 5-13 (.278) when tied entering the 8th inning in the 2024 season — 3rd lowest in MLB; League Avg: .500.

The Reds batted just .116 on pitches out of the zone in the 2024 season — lowest in MLB; League Avg: .150.

Reds hitters slugged just .151 on pitches out of the zone in the 2024 season — lowest in MLB; League Avg: .204.

The Reds are batting just .118 on pitches out of the zone since last season — lowest in MLB; League Avg: .150.

Reds hitters are slugging just .155 on pitches out of the zone since last season — lowest in MLB; League Avg: .204.

Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.

Astros hitters have put just 29% of balls in play to the right side of the field this season — lowest in MLB; League Avg: 38%.

Astros hitters averaged just 3.66 pitches per plate appearance in the 2024 season — lowest in MLB; League Avg: 3.89.

Astros hitters have put 46% of balls in play to the left side of the field this season — highest in MLB; League Avg: 37%.

Opponents had a groundball rate of just 39% against Reds pitchers in 2023 — 2nd lowest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 39% against Reds pitchers since the 2023 season — lowest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 38% against Reds pitchers this season — lowest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 39% against Reds pitchers since last season — lowest in MLB; League Avg: 43%.

Astros pitchers have walked 13% of batters this month (8 game{NumGameSuffix}) — highest in MLB; League Avg: 8%.

Opponents have a miss rate of 29% against Astros pitchers this season — best in MLB; League Avg: 25%.

Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 25%.

Astros pitchers have a strikeout rate of 33% in close and late situations this season — best in MLB; League Avg: 24%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.