Reds vs Marlins Prediction, Odds & Player Prop Bets Today – MLB, Apr 21

(AP Photo/Lynne Sladky)
  • The Reds are -125 favorites vs the Marlins
  • Reds vs Marlins Over / Under today: 8 Runs
  • Reds / Marlins TV Channel: FDOH | FDFL

The Cincinnati Reds (-125) visit loanDepot park to take on the Miami Marlins (+105) on Monday, April 21, 2025. First pitch is scheduled for 6:40pm EDT in Miami, FL, FL.

This season, the Reds are 11-11 against the spread (ATS), while the Marlins are 10-11 ATS.

Reds vs Marlins Starting Pitchers Today:

  • Reds starting pitcher: Nick Lodolo 2-1, 2.32 ERA
  • Marlins starting pitcher: Max Meyer 1-2, 2.66 ERA

Reds vs. Marlins Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Reds-1.5 +135O 8 -110-125
Marlins +1.5 -165U 8 -110+105

Reds vs Marlins Prediction for Today’s Game

Based on recent trends the model predicts the Reds will win Monday‘s MLB game with 56.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Reds players for Monday‘s game, looking at profitable historical betting trends:

Best Reds Player Prop Bets Today:

  • Austin Hays has hit the Home Runs Over in 4 of his last 8 games (+16.90 Units / 211% ROI)
  • Santiago Espinal has hit the Runs Under in 21 of his last 25 away games (+13.00 Units / 23% ROI)
  • Jeimer Candelario has hit the Singles Under in 14 of his last 15 games (+12.20 Units / 50% ROI)
  • Jeimer Candelario has hit the Hits Runs and RBIs Under in 19 of his last 25 games (+11.25 Units / 33% ROI)
  • Jeimer Candelario has hit the Total Bases Under in 16 of his last 25 games (+9.10 Units / 33% ROI)

And here are some favorite MLB player prop bets for Marlins players for Monday‘s game, looking at profitable historical betting trends:

Best Marlins Player Prop Best Bets Today:

  • Connor Norby has hit the Hits Over in 19 of his last 20 games at home (+18.05 Units / 47% ROI)
  • Otto Lopez has hit the Total Bases Over in 16 of his last 25 games at home (+11.05 Units / 36% ROI)
  • Connor Norby has hit the Home Runs Over in 3 of his last 9 games at home (+10.70 Units / 119% ROI)
  • Otto Lopez has hit the Runs Over in 12 of his last 20 games at home (+10.10 Units / 50% ROI)
  • Kyle Stowers has hit the Singles Over in 9 of his last 15 games (+8.40 Units / 56% ROI)
  • The Cincinnati Reds have hit the Team Total Under in 94 of their last 164 games (+15.30 Units / 8% ROI)
  • The Cincinnati Reds have covered the Run Line in 52 of their last 82 away games (+10.35 Units / 8% ROI)
  • The Cincinnati Reds have hit the Game Total Under in 84 of their last 164 games (+6.15 Units / 3% ROI)
  • The Cincinnati Reds have covered the 1st Five Innings (F5) Run Line in 9 of their last 12 games (+5.75 Units / 39% ROI)
  • The Cincinnati Reds have hit the 1st Five Innings (F5) Moneyline in 8 of their last 11 games (+4.75 Units / 33% ROI)
  • The Miami Marlins have hit the Game Total Over in 54 of their last 81 games at home (+30.95 Units / 34% ROI)
  • The Miami Marlins have hit the Team Total Over in 49 of their last 81 games at home (+12.20 Units / 13% ROI)
  • The Miami Marlins have hit the Moneyline in 66 of their last 161 games (+0.75 Units / 0% ROI)

Reds Against the Spread (ATS) Record

Against the spread this season, the Reds are 13-9 against the Run Line (+0.65 Units / 1.95% ROI).

  • 11-11 when betting on the Moneyline for +0.85 Units / 3.43% ROI
  • 11-10 when betting on the total runs Over for +0.1 Units / 0.41% ROI
  • 10-11 when betting on the total runs Under for -1.95 Units / -8.07% ROI

Marlins Against the Spread (ATS) Record

Against the spread this season, the Marlins are 10-11 against the Run Line (-2.4 Units / -9.49% ROI).

  • 9-12 when betting on the Moneyline for +1.2 Units / 5.52% ROI
  • 14-7 when betting on the total runs Over for +6 Units / 25.42% ROI
  • 7-14 when betting on the total runs Under for -8.2 Units / -36.28% ROI

Marlins vs Reds Home Run Prop Bets Today

Over Under
Elly De La Cruz (CIN) 0.5 +575 0.5 -800
Austin Hays (CIN) 0.5 +575 0.5 -900
Connor Norby (MIA) 0.5 +725 0.5 -1200
Matt McLain (CIN) 0.5 +725 0.5 -1200
Spencer Steer (CIN) 0.5 +775 0.5 -1200

Marlins vs Reds Total Hits Prop Bets Today

Over Under
Xavier Edwards (MIA) 0.5 -250 0.5 +185
Otto Lopez (MIA) 0.5 -235 0.5 +175
Gavin Lux (CIN) 0.5 -220 0.5 +165
TJ Friedl (CIN) 0.5 -210 0.5 +155
Elly De La Cruz (CIN) 0.5 -200 0.5 +150

Marlins vs Reds RBI Prop Bets Today

Over Under
Austin Hays (CIN) 0.5 +145 0.5 -190
Elly De La Cruz (CIN) 0.5 +170 0.5 -225
Gavin Lux (CIN) 0.5 +200 0.5 -275
Connor Norby (MIA) 0.5 +200 0.5 -275
Eric Wagaman (MIA) 0.5 +210 0.5 -285

Marlins vs Reds Strikeout Prop Bets Today

Over Under
Nick Lodolo (CIN) 4.5 -160 4.5 +125
Max Meyer (MIA) 5.5 +125 5.5 -165

Nick Lodolo has not walked any of the 36 batters that they have faced when going through the lineup the second time in a game this season — tied for best among qualified SPs in MLB; League Avg: 7% — 100th Percentile.

Nick Lodolo has a strikeout rate of just 15% (14 SO in 92 PAs) this season — 4th lowest among qualified SPs in MLB; League Avg: 24% — fourth Percentile.

Nick Lodolo has walked 2% of batters this season — 3rd best among qualified SPs in MLB; League Avg: 8% — 97th Percentile.

Nick Lodolo has a strikeout rate of just 11% (4 SO in 36 PAs) when going through the lineup the first time in a game this season — 3rd lowest among qualified SPs in MLB; League Avg: 25% — third Percentile.

Marlins Starting Pitcher Stats & Trends

Right-handed hitters have a miss rate of 41% (32/79) against Max Meyer this season — 3rd best among qualified SPs in MLB; League Avg: 26% — 97th Percentile.

Opponents have a line drive rate of just 16% (40/244) against Max Meyer since last season — lowest in MLB among starting pitchers with at least 72 total IP; League Avg: 24% — 100th Percentile.

Max Meyer has a strikeout rate of 39% (14 SO in 36 PAs) when going through the lineup the first time in a game this season — tied for 4th best among qualified SPs in MLB; League Avg: 25% — 96th Percentile.

Max Meyer has thrown his slider 47% of the time (93/200) vs left-handed batters this season — highest among among NL Starters; League Avg: 20% — 100th Percentile.

Reds Keys to the Game vs. the Marlins

The Reds are just 14-27 (.341) when tied entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Reds were just 8-18 (.308) when tied entering the 7th inning in the 2024 season — tied for 2nd lowest in MLB; League Avg: .498.

The Reds were just 5-16 (.238) when tied entering the 8th inning in the 2024 season — lowest in MLB; League Avg: .500.

The Reds are just 0-9 (.000) when trailing entering the 8th inning this season — tied for lowest in MLB; League Avg: .081.

Marlins Keys to the Game vs. the Reds

The Marlins were just 30-51 (.370) at home in the 2024 season — 2nd lowest in MLB; League Avg: .521.

The Marlins were just 14-31 (.311) vs bottom 10 scoring offenses in the 2024 season They play the Mets (seventh best runs scored) today.

The Marlins are just 19-36 (.345) vs bottom 10 scoring offenses since last season They play the Reds (16th best runs scored) today.

The Marlins are just 22-47 (.319) after a win since last season — 2nd lowest in MLB; League Avg: .495.

Reds hitters have chased 25% of pitches out of the zone against LHP this season — lowest in MLB; League Avg: 29%.

The Reds are batting just .116 on pitches out of the zone since last season — lowest in MLB; League Avg: .149.

Reds hitters slugged just .151 on pitches out of the zone in the 2024 season — lowest in MLB; League Avg: .204.

The Reds are batting just .126 on pitches out of the zone since the 2023 season — tied for lowest in MLB; League Avg: .150.

The Marlins had a winning percentage of just 37% at home last season — 2nd lowest in MLB; League Avg: 52%.

Marlins hitters pulled just 42% of balls they’ve put into play against RHP in 2023 — lowest in MLB; League Avg: 47%.

Marlins hitters pulled just 42% of balls they’ve put into play in 2023 — lowest in MLB; League Avg: 47%.

The Marlins batted .281 against LHP in the 2023 season — 2nd best in MLB; League Avg: .254.

Opponents have a groundball rate of just 39% against Reds pitchers since the 2023 season — lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of just 39% against Reds pitchers in 2023 — 2nd lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of just 39% against Reds pitchers in the 2024 season — lowest in MLB; League Avg: 43%.

Opponents have a groundball rate of just 39% against Reds pitchers since last season — lowest in MLB; League Avg: 43%.

Opponents have a miss rate of just 22% against Marlins pitchers this season — 2nd lowest in MLB; League Avg: 26%.

Marlins pitchers had an ERA of 5.37 (751.0 IP) at home in the 2024 season — 2nd highest in MLB; League Avg: 3.98.

Marlins pitchers have walked 11% of batters this season — 2nd highest in MLB; League Avg: 9%.

The Marlins allowed 6.04 runs per game (489/81) at home in the 2024 season — highest in MLB; League Avg: 4.41.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.