Seattle Mariners vs Chicago Cubs Prediction, Odds & Player Prop Bets Today – MLB, Jun 21

  • The Chicago Cubs are -175 favorites vs the Seattle Mariners
  • Seattle Mariners vs Chicago Cubs Over / Under today: 13 Runs
  • Seattle Mariners / Chicago Cubs TV Channel: MARQ | RTNW

The Seattle Mariners (+145) visit Wrigley Field to take on the Chicago Cubs (-175) on Saturday, June 21, 2025. First pitch is scheduled for 2:20pm EDT in Chicago, IL, IL.

This season, the Seattle Mariners are 38-36 against the spread (ATS), while the Chicago Cubs are 37-38 ATS.

Seattle Mariners vs Chicago Cubs Starting Pitchers Today:

  • Seattle Mariners starting pitcher: , ERA
  • Chicago Cubs starting pitcher: , ERA

Seattle Mariners vs. Chicago Cubs Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Seattle Mariners+1.5 -120O 12.5 -118+145
Chicago Cubs -1.5 +100U 12.5 -102-175

Seattle Mariners vs Chicago Cubs Prediction for Today’s Game

Based on recent trends the model predicts the will win Saturday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Seattle Mariners players for Saturday‘s game, looking at profitable historical betting trends:

Best Seattle Mariners Player Prop Bets Today:

  • Julio Rodriguez has hit the Hits Over in 17 of his last 25 away games (+14.70 Units / 41% ROI)
  • Jorge Polanco has hit the Runs Under in 20 of his last 25 games (+12.50 Units / 30% ROI)
  • Jorge Polanco has hit the Total Bases Under in 17 of his last 25 games (+9.15 Units / 28% ROI)
  • Cal Raleigh has hit the Singles Over in 13 of his last 25 games (+7.45 Units / 30% ROI)
  • J.P. Crawford has hit the Walks Over in 14 of his last 25 games (+7.25 Units / 29% ROI)

And here are some favorite MLB player prop bets for Chicago Cubs players for Saturday‘s game, looking at profitable historical betting trends:

Best Chicago Cubs Player Prop Best Bets Today:

  • Seiya Suzuki has hit the Singles Under in 21 of his last 25 games at home (+15.65 Units / 47% ROI)
  • Pete Crow-Armstrong has hit the Home Runs Over in 3 of his last 7 games (+12.40 Units / 177% ROI)
  • Seiya Suzuki has hit the Runs Under in 18 of his last 25 games at home (+9.30 Units / 27% ROI)
  • Michael Busch has hit the Hits Over in 15 of his last 20 games (+7.95 Units / 23% ROI)
  • Matt Shaw has hit the Total Bases Under in 7 of his last 8 games at home (+7.35 Units / 92% ROI)
  • The Seattle Mariners have hit the Game Total Over in 35 of their last 62 games (+7.55 Units / 11% ROI)
  • The Seattle Mariners have hit the Team Total Under in 15 of their last 24 games (+5.45 Units / 20% ROI)
  • The Seattle Mariners have hit the 1st Five Innings (F5) Team Total Over in 38 of their last 68 games (+5.40 Units / 7% ROI)
  • The Seattle Mariners have hit the Moneyline in 18 of their last 31 away games (+4.75 Units / 13% ROI)
  • The Seattle Mariners have covered the Run Line in 3 of their last 5 games (+1.40 Units / 22% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 38 of their last 73 games (+12.70 Units / 12% ROI)
  • The Chicago Cubs have hit the Moneyline in 43 of their last 69 games (+11.25 Units / 11% ROI)
  • The Chicago Cubs have hit the Game Total Under in 15 of their last 22 games (+9.45 Units / 39% ROI)
  • The Chicago Cubs have hit the Team Total Under in 15 of their last 22 games (+7.25 Units / 29% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 40 of their last 71 games (+5.85 Units / 7% ROI)

Seattle Mariners Against the Spread (ATS) Record

Against the spread this season, the Seattle Mariners are 33-41 against the Run Line (-8.35 Units / -9.09% ROI).

  • 38-36 when betting on the Moneyline for -7.6 Units / -7.73% ROI
  • 38-32 when betting on the total runs Over for +2.85 Units / 3.52% ROI
  • 32-38 when betting on the total runs Under for -9.92 Units / -12.12% ROI

Chicago Cubs Against the Spread (ATS) Record

Against the spread this season, the Chicago Cubs are 37-38 against the Run Line (-0.23 Units / -0.25% ROI).

  • 45-30 when betting on the Moneyline for +9.15 Units / 8.24% ROI
  • 37-33 when betting on the total runs Over for +1.25 Units / 1.53% ROI
  • 33-37 when betting on the total runs Under for -7.95 Units / -9.53% ROI

Chicago Cubs vs Seattle Mariners Home Run Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 +165 0.5 -200
Seiya Suzuki (CHC) 0.5 +225 0.5 -275
Kyle Tucker (CHI) 0.5 +240 0.5 -300
Ian Happ (CHC) 0.5 +260 0.5 -325
Pete Crow-Armstrong (CHC) 0.5 +260 0.5 -325

Chicago Cubs vs Seattle Mariners Total Hits Prop Bets Today

Over Under
Matt Shaw (CHC) 0.5 -235 0.5 +175
Carson Kelly (CHC) 0.5 -235 0.5 +175
Dominic Canzone (SEA) 0.5 -225 0.5 +175
Ben Williamson (SEA) 0.5 -220 0.5 +165
Randy Arozarena (SEA) 0.5 -210 0.5 +160

Chicago Cubs vs Seattle Mariners RBI Prop Bets Today

Over Under
Cal Raleigh (SEA) 0.5 -120 0.5 -110
Seiya Suzuki (CHC) 0.5 -115 0.5 -115
Pete Crow-Armstrong (CHC) 0.5 -110 0.5 -118
Kyle Tucker (CHI) 0.5 +105 0.5 -140
Dansby Swanson (CHC) 0.5 +105 0.5 -135

Chicago Cubs vs Seattle Mariners Strikeout Prop Bets Today

Over Under
Cade Horton (CHC) 4.5 -115 4.5 -115
Emerson Hancock (SEA) 3.5 +115 3.5 -155

starting pitcher – away

Chicago Cubs Starting Pitcher Stats & Trends

starting pitcher – home

Seattle Mariners Keys to the Game vs. the Chicago Cubs

keys to the game – away

Chicago Cubs Keys to the Game vs. the Seattle Mariners

keys to the game – home

team hitters – away

team hitters – home

team pitchers – away

team pitchers – home

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.