White Sox vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, May 3

MLB betting odds, predictions and betting odds for today's games
(AP Photo)
  • The Cardinals are -275 favorites vs the White Sox
  • White Sox vs Cardinals Over / Under today: 7.5 Runs
  • White Sox / Cardinals TV Channel: NSCH | BSMW

The Chicago White Sox (+220) visit Busch Stadium to take on the St. Louis Cardinals (-275) on Friday, May 3, 2024. First pitch is scheduled for 8:15pm EDT in St. Louis, MO.

This season, the White Sox are 6-25 against the spread (ATS), while the Cardinals are 17-14 ATS.

White Sox vs Cardinals Starting Pitchers Today:

  • White Sox starting pitcher: Brad Keller 0-0, 0.00 ERA
  • Cardinals starting pitcher: Sonny Gray 3-1, 1.16 ERA

White Sox vs. Cardinals Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox+1.5 +105O 7.5 -105+220
Cardinals -1.5 -125U 7.5 -115-275

White Sox vs Cardinals Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Friday‘s MLB game with 70.2% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for White Sox players for Friday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Andrew Benintendi has hit the Home Runs Over in 2 of his last 5 games (+14.00 Units / 280% ROI)
  • Andrew Vaughn has hit the Total Bases Under in 21 of his last 29 games (+11.45 Units / 27% ROI)
  • Andrew Vaughn has hit the Hits Under in 15 of his last 27 games (+8.05 Units / 24% ROI)
  • Eloy Jimenez has hit the Runs Over in 6 of his last 10 games (+6.00 Units / 60% ROI)
  • Andrew Vaughn has hit the Singles Over in 7 of his last 9 games (+5.80 Units / 63% ROI)

And here are some favorite MLB player prop bets for Cardinals players for Friday‘s game, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today:

  • Alec Burleson has hit the Home Runs Over in 2 of his last 5 games (+14.00 Units / 280% ROI)
  • Nolan Gorman has hit the Runs Under in 15 of his last 16 games (+12.90 Units / 41% ROI)
  • Nolan Arenado has hit the Singles Over in 21 of his last 29 games (+12.85 Units / 41% ROI)
  • Nolan Arenado has hit the Hits Over in 23 of his last 29 games (+11.35 Units / 18% ROI)
  • Brendan Donovan has hit the Hits Runs and RBIs Under in 16 of his last 22 games (+10.80 Units / 45% ROI)
  • The Chicago White Sox have hit the Game Total Under in 70 of their last 124 games (+16.15 Units / 12% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 12 of their last 16 away games (+8.13 Units / 45% ROI)
  • The Chicago White Sox have hit the Team Total Under in 13 of their last 19 away games (+6.45 Units / 30% ROI)
  • The Chicago White Sox have covered the Run Line in 15 of their last 22 away games (+6.40 Units / 21% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 4 of their last 6 away games (+1.84 Units / 27% ROI)
  • The St. Louis Cardinals have hit the Game Total Under in 32 of their last 58 games (+5.80 Units / 9% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 13 of their last 26 games (+5.50 Units / 21% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 11 games (+4.82 Units / 37% ROI)
  • The St. Louis Cardinals have covered the Run Line in 49 of their last 92 games (+1.55 Units / 1% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 14-17 against the Run Line (-5.8 Units / -15.93% ROI).

  • 6-25 when betting on the Moneyline for -16.6 Units / -55.33% ROI
  • 15-14 when betting on the total runs Over for -0.6 Units / -1.8% ROI
  • 14-15 when betting on the total runs Under for -2.3 Units / -7.03% ROI

Cardinals Against the Spread (ATS) Record

Against the spread this season, the Cardinals are 17-14 against the Run Line (+1.65 Units / 3.92% ROI).

  • 14-17 when betting on the Moneyline for -3.9 Units / -10.77% ROI
  • 10-19 when betting on the total runs Over for -11.05 Units / -32.31% ROI
  • 19-10 when betting on the total runs Under for +8.1 Units / 23.79% ROI

Cardinals vs White Sox Home Run Prop Bets Today

Over Under
Willson Contreras (STL) 0.5 +425 0.5 -650
Nolan Gorman (STL) 0.5 +525 0.5 -750
Nolan Arenado (STL) 0.5 +550 0.5 -800
Paul Goldschmidt (STL) 0.5 +550 0.5 -800
Tommy Pham (CWS) 0.5 +675 0.5 -1100

Cardinals vs White Sox Total Hits Prop Bets Today

Over Under
Brendan Donovan (STL) 0.5 -275 0.5 +200
Alec Burleson (STL) 0.5 -250 0.5 +175
Nicky Lopez (CWS) 0.5 -250 0.5 +175
Nolan Arenado (STL) 0.5 -225 0.5 +165
Tommy Pham (CWS) 0.5 -225 0.5 +165

Cardinals vs White Sox RBI Prop Bets Today

Over Under
Nolan Arenado (STL) 0.5 +125 0.5 -165
Paul Goldschmidt (STL) 0.5 +140 0.5 -185
Willson Contreras (STL) 0.5 +150 0.5 -200
Alec Burleson (STL) 0.5 +155 0.5 -210
Nolan Gorman (STL) 0.5 +165 0.5 -225

Cardinals vs White Sox Strikeout Prop Bets Today

Over Under

Brad Keller has walked 104 of 836 batters (12%) since the 2022 season — 3rd highest in MLB among starting pitchers with at least 141 total IP; League Avg: 8% — first Percentile.

Brad Keller has a strike rate of just 60% (1,915/3,183) since the 2022 season — 4th lowest in MLB among starting pitchers with at least 141 total IP; League Avg: 65% — second Percentile.

Opponents have a miss rate of just 17% (38/230) against Brad Keller on the first pitch of at-bats since the 2022 season — 2nd lowest in MLB among starting pitchers with at least 141 total IP; League Avg: 26% — first Percentile.

Brad Keller has thrown at least two strikes in his first three pitches to 56% (331/595) of opposing batters since the 2022 season — 3rd lowest in MLB among starting pitchers with at least 141 total IP; League Avg: 65% — first Percentile.

Cardinals Starting Pitcher Stats & Trends

Sonny Gray has a strikeout rate of 56% (10 SO in 18 PAs) when going through the lineup the second time in a game over the last 14 days — best in NL over the last two weeks; League Avg: 22% — 100th Percentile.

Sonny Gray has allowed an OPS of just .543 (324 PA’s) when going through the lineup the first time in a game since last season — best among qualified SPs in MLB; League Avg: .670 — 100th Percentile.

Sonny Gray has allowed a slugging percentage of just .285 (87 Total Bases / 305 ABs) when going through the lineup the first time in a game since last season — best among qualified SPs in MLB; League Avg: .382 — 100th Percentile.

Sonny Gray has allowed a slugging percentage of just .121 (27 Total Bases / 224 ABs) on sliders since last season — best in MLB among starting pitchers with at least 76 total IP; League Avg: .398 — 100th Percentile.

White Sox Keys to the Game vs. the Cardinals

The White Sox are just 21-46 (.313) after a win since the 2023 season — lowest in MLB; League Avg: .507.

The White Sox are just 53-13 (.803) when leading entering the 8th inning since the 2023 season — 2nd lowest in MLB; League Avg: .898.

The White Sox are just 8-23 (.258) after a road win since the 2023 season — lowest in MLB; League Avg: .490.

The White Sox are just 52-41 (.559) when allowing 4 or fewer runs since the 2023 season — lowest in MLB; League Avg: .732.

Cardinals Keys to the Game vs. the White Sox

The Cardinals are 28-11 (.718) when tied entering the 8th inning since the 2022 season — best in MLB; League Avg: .500.

The Cardinals are just 36-49 (.424) after a win since the 2023 season — 5th lowest in MLB; League Avg: .507.

The Cardinals are just 71-6 (.922) when leading entering the 9th inning since the 2023 season — 5th lowest in MLB; League Avg: .948.

The Cardinals are just 23-31 (.426) after a home loss since the 2023 season — 5th lowest in MLB; League Avg: .512.

White Sox hitters have an OBP of just .260 (151 PA’s) when facing the starting pitcher for the 3rd time in a game this season — lowest in MLB; League Avg: .328.

White Sox hitters have an OPS of just .517 (193 PA’s) against LHP this season — lowest in MLB; League Avg: .701.

White Sox hitters have an OBP of just .288 (5,510 PA’s) against RHP since last season — lowest in MLB; League Avg: .318.

White Sox hitters have an OBP of just .289 (3,548 PA’s) at home since last season — lowest in MLB; League Avg: .323.

The Cardinals are batting just .192 against LHP this season — 3rd lowest in MLB; League Avg: .244.

The Cardinals are batting just .237 against LHP since last season — 2nd lowest in MLB; League Avg: .253.

The Cardinals have an average HR distance of 412.0 feet this season — 2nd best in MLB; League Avg: 395.7.

Cardinals hitters are slugging just .310 against LHP this season — 3rd lowest in MLB; League Avg: .384.

Opponents have a groundball rate of just 41% against White Sox pitchers since last season — 3rd lowest in MLB; League Avg: 43%.

White Sox pitchers have walked 1,313 of 13,642 batters (10%) since the 2022 season — tied for 2nd highest in MLB; League Avg: 8%.

Opponents have a groundball rate of just 41% against White Sox pitchers since the 2022 season — tied for 3rd lowest in MLB; League Avg: 43%.

The White Sox have won just 10% of games in which their opponents scored first this season — lowest in MLB; League Avg: 32%.

Opponents have a miss rate of just 23% against Cardinals pitchers since the 2022 season — 2nd lowest in MLB; League Avg: 26%.

Opponents have a groundball rate of 47% against Cardinals pitchers since the 2022 season — 2nd highest in MLB; League Avg: 43%.

Cardinals pitchers have walked 15 of 275 batters (6%) when facing the leadoff batter in the inning this season — 3rd best in MLB; League Avg: 8%.

Cardinals pitchers have a strikeout rate of just 20% since last season — 3rd lowest in MLB; League Avg: 23%.

Cardinals vs. White Sox Injuries Tonight That May Affect Prop Bets 

  • Dylan Carlson (St. Louis Cardinals): Shoulder, 10-Day IL
  • Keynan Middleton (St. Louis Cardinals): Forearm, 15-Day IL
  • Lars Nootbaar (St. Louis Cardinals): Ribs, 10-Day IL
  • Drew Rom (St. Louis Cardinals): Biceps, 15-Day IL
  • Sonny Gray (St. Louis Cardinals): Hamstring, 15-Day IL
  • Riley O’Brien (St. Louis Cardinals): Forearm, 15-Day IL
  • Tommy Edman (St. Louis Cardinals): Wrist, 10-Day IL
  • Packy Naughton (St. Louis Cardinals): Elbow, Out
  • Eloy Jimenez (Chicago White Sox): Thigh, Day-To-Day
  • Yasmani Grandal (Chicago White Sox): Foot, 10-Day IL
  • Matt Foster (Chicago White Sox): Elbow, 60-Day IL
  • Jake Eder (Chicago White Sox): Shoulder, Day-To-Day
  • Jesse Scholtens (Chicago White Sox): Elbow, 60-Day IL
  • Shane Drohan (Chicago White Sox): Shoulder, 60-Day IL
  • Liam Hendriks (Chicago White Sox): Elbow, 60-Day IL
  • Jimmy Lambert (Chicago White Sox): Shoulder, 60-Day IL
  • Edgar Navarro (Chicago White Sox): Elbow, Out
  • Davis Martin (Chicago White Sox): Elbow, Out
  • Max Stassi (Chicago White Sox): Hip, 10-Day IL

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.