White Sox vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Apr 8

Cleveland Guardians' Jhonkensy Noel celebrates after hitting a two-run home run against the New York Yankees during the ninth inning in Game 3 of the baseball AL Championship Series Thursday, Oct. 17, 2024, in Cleveland.
(AP Photo/Sue Ogrocki)
  • The Guardians are -210 favorites vs the White Sox
  • White Sox vs Guardians Over / Under today: 7.5 Runs
  • White Sox / Guardians TV Channel: GDTV | MLBN | CHS+

The Chicago White Sox (+170) visit Progressive Field to take on the Cleveland Guardians (-210) on Tuesday, April 8, 2025. First pitch is scheduled for 4:10pm EDT in Cleveland, OH.

This season, the White Sox are 2-7 against the spread (ATS), while the Guardians are 4-5 ATS.

White Sox vs Guardians Starting Pitchers Today:

  • White Sox starting pitcher: Shane Smith 0-0, 3.18 ERA
  • Guardians starting pitcher: Ben Lively 0-1, 6.76 ERA

White Sox vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox+1.5 -130O 7.5 -120+170
Guardians -1.5 +105U 7.5 +100-210

White Sox vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Tuesday‘s MLB game with 63.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for White Sox players for Tuesday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Korey Lee has hit the Home Runs Over in 2 of his last 7 games (+10.10 Units / 144% ROI)
  • Brooks Baldwin has hit the Hits Under in 13 of his last 20 away games (+8.65 Units / 43% ROI)
  • Brooks Baldwin has hit the Singles Under in 15 of his last 20 away games (+8.20 Units / 28% ROI)
  • Brooks Baldwin has hit the Total Bases Under in 13 of his last 20 away games (+6.40 Units / 28% ROI)
  • Luis Robert has hit the Hits Runs and RBIs Under in his last 5 games (+5.40 Units / 78% ROI)

And here are some favorite MLB player prop bets for Guardians players for Tuesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • Kyle Manzardo has hit the Home Runs Over in 4 of his last 9 games at home (+15.90 Units / 177% ROI)
  • Gabriel Arias has hit the Singles Under in his last 10 games at home (+10.00 Units / 70% ROI)
  • Gabriel Arias has hit the Total Bases Under in 8 of his last 10 games at home (+8.40 Units / 84% ROI)
  • Gabriel Arias has hit the Hits Under in 8 of his last 10 games at home (+8.40 Units / 84% ROI)
  • Gabriel Arias has hit the Hits Runs and RBIs Under in 9 of his last 10 games at home (+7.65 Units / 52% ROI)
  • The Chicago White Sox have hit the Team Total Under in 25 of their last 37 away games (+12.40 Units / 29% ROI)
  • The Chicago White Sox have hit the Game Total Under in 20 of their last 34 away games (+9.15 Units / 25% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 8 of their last 13 away games (+3.65 Units / 26% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 5 of their last 13 away games (+3.30 Units / 25% ROI)
  • The Chicago White Sox have hit the Moneyline in 5 of their last 13 away games (+2.80 Units / 22% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 47 of their last 79 games (+17.00 Units / 19% ROI)
  • The Cleveland Guardians have covered the Run Line in 41 of their last 82 games at home (+10.15 Units / 11% ROI)
  • The Cleveland Guardians have hit the Moneyline in 51 of their last 81 games at home (+10.10 Units / 9% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 6 of their last 7 games at home (+5.75 Units / 70% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 7 of their last 10 games at home (+3.60 Units / 29% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 5-4 against the Run Line (+0.4 Units / 3.62% ROI).

  • 2-7 when betting on the Moneyline for -4 Units / -44.44% ROI
  • 5-3 when betting on the total runs Over for +1.7 Units / 17.17% ROI
  • 3-5 when betting on the total runs Under for -2.55 Units / -25.76% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 4-5 against the Run Line (-2.2 Units / -16.54% ROI).

  • 3-6 when betting on the Moneyline for -3.15 Units / -31.82% ROI
  • 5-4 when betting on the total runs Over for +0.85 Units / 8.72% ROI
  • 4-5 when betting on the total runs Under for -1.4 Units / -13.93% ROI

Guardians vs White Sox Home Run Prop Bets Today

Over Under
Jose Ramirez (CLE) 0.5 +475 0.5 -650
Kyle Manzardo (CLE) 0.5 +625 0.5 -1000
Luis Robert (CWS) 0.5 +650 0.5 -1100
Carlos Santana (CLE) 0.5 +650 0.5 -1000
Andrew Vaughn (CWS) 0.5 +725 0.5 -1200

Guardians vs White Sox Total Hits Prop Bets Today

Over Under
Jose Ramirez (CLE) 0.5 -235 0.5 +175
Steven Kwan (CLE) 0.5 -210 0.5 +160
Lenyn Sosa (CWS) 0.5 -200 0.5 +150
Andrew Vaughn (CWS) 0.5 -200 0.5 +150
Luis Robert (CWS) 0.5 -185 0.5 +140

Guardians vs White Sox RBI Prop Bets Today

Over Under
Jose Ramirez (CLE) 0.5 +170 0.5 -220
Kyle Manzardo (CLE) 0.5 +180 0.5 -235
Carlos Santana (CLE) 0.5 +195 0.5 -275
Andrew Vaughn (CWS) 0.5 +200 0.5 -275
Lane Thomas (CLE) 0.5 +220 0.5 -300

Guardians vs White Sox Strikeout Prop Bets Today

Over Under
Shane Smith (CWS) 3.5 -165 3.5 +130

Shane Smith has allowed a slugging percentage of just .111 (2 Total Bases / 18 ABs) this season — 5th best in MLB among starting pitchers with at least 3 total IP; League Avg: .401 — 97th Percentile.

Opponents are hitting just .111 (2-for-18) against Shane Smith this season — 6th best in MLB among starting pitchers with at least 3 total IP; League Avg: .240 — 96th Percentile.

Shane Smith has walked 4 of 22 batters (18%) this season — tied for 9th highest in MLB among starting pitchers with at least 3 total IP; League Avg: 9% — sixth Percentile.

Opponents have a groundball batting average of just .000 (0 GB hits out of 9 GBs) against Shane Smith this season — tied for best in MLB among starting pitchers with at least 3 total IP; League Avg: .245 — 100th Percentile.

Guardians Starting Pitcher Stats & Trends

Opponents are hitting .412 (7-for-17) against Ben Lively when going through the lineup the second time in a game this season — tied for 2nd highest among among AL Starters; League Avg: .217 — sixth Percentile.

Opponents have a miss rate of just 14% (11/78) against Ben Lively this season — 2nd lowest among among AL Starters; League Avg: 25% — third Percentile.

Ben Lively has a strikeout rate of just 6% (1 SO in 18 PAs) when going through the lineup the second time in a game this season — tied for 2nd lowest among among AL Starters; League Avg: 23% — ninth Percentile.

Opponents have a miss rate of just 14% (11/78) against Ben Lively this season — 3rd lowest among qualified SPs in MLB; League Avg: 26% — second Percentile.

White Sox Keys to the Game vs. the Guardians

The White Sox were just 23-58 (.284) at home in the 2024 season — lowest in MLB; League Avg: .521.

The White Sox were just 40-103 (.280) when allowing 5 or more extra base hits in the 2024 season — lowest in MLB; League Avg: .538.

The White Sox were just 18-63 (.222) on the road in the 2024 season — lowest in MLB; League Avg: .478.

The White Sox were just 41-121 (.253) in the 2024 season — lowest in MLB; League Avg: .500.

Guardians Keys to the Game vs. the White Sox

The Guardians were 71-2 (.973) when leading entering the 7th inning in the 2024 season — best in MLB; League Avg: .856.

The Guardians were 77-2 (.975) when leading entering the 8th inning in the 2024 season — best in MLB; League Avg: .899.

The Guardians were 82-0 (1.000) when leading entering the 9th inning in the 2024 season — best in MLB; League Avg: .949.

The Guardians were 25-2 (.926) when they had 5 or more XBH in the 2024 season — 4th best in MLB; League Avg: .809.

White Sox hitters have an OBP of just .283 (9,231 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .315.

White Sox hitters have an OBP of just .290 (2,934 PA’s) against LHP since the 2023 season — lowest in MLB; League Avg: .318.

The White Sox had a winning percentage of just 28% at home last season — lowest in MLB; League Avg: 52%.

White Sox hitters have an OBP of just .284 (12,165 PA’s) since the 2023 season — lowest in MLB; League Avg: .316.

Guardians hitters had an OPS of just .662 (1,910 PA’s) against LHP in the 2023 season — lowest in MLB; League Avg: .742.

The Guardians batted just .232 against LHP in the 2023 season — tied for lowest in MLB; League Avg: .254.

Guardians hitters slugged just .367 against LHP in the 2023 season — lowest in MLB; League Avg: .419.

The Guardians have an average Exit Velocity of 87.6 MPH since the 2023 season — lowest in MLB; League Avg: 88.9.

White Sox pitchers have walked 678 of 6,577 batters (10%) since last season — highest in MLB; League Avg: 8%.

The White Sox have won just 17% of games in which their opponents scored first since the 2023 season — lowest in MLB; League Avg: 33%.

The White Sox won just 11% of games in which their opponents scored first last season — lowest in MLB; League Avg: 31%.

The White Sox won just 13% of home games in which their opponents scored first last season — lowest in MLB; League Avg: 35%.

Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.

Opponents have a groundball batting average of just .211 against Guardians pitchers with runners on base since last season — best in MLB; League Avg: .262.

Guardians pitchers have a strikeout rate of just 34% with two-strikes this season — lowest in MLB; League Avg: 42%.

Guardians pitchers have a strikeout rate of just 17% this season — lowest in MLB; League Avg: 23%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.