White Sox vs Orioles Prediction, Odds & Player Prop Bets Today – MLB, May 30

(AP Photo/Nick Wass)
  • The Orioles are -220 favorites vs the White Sox
  • White Sox vs Orioles Over / Under today: 9 Runs
  • White Sox / Orioles TV Channel: MASN | CHSN

The Chicago White Sox (+180) visit Oriole Park at Camden Yards to take on the Baltimore Orioles (-220) on Friday, May 30, 2025. First pitch is scheduled for 7:05pm EDT in Baltimore, MD.

This season, the White Sox are 18-38 against the spread (ATS), while the Orioles are 18-36 ATS.

White Sox vs Orioles Starting Pitchers Today:

  • White Sox starting pitcher: Sean Burke 3-5, 4.39 ERA
  • Orioles starting pitcher: Zach Eflin 3-2, 5.46 ERA

White Sox vs. Orioles Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox+1.5 -110O 9 -110+180
Orioles -1.5 -110U 9 -110-220

White Sox vs Orioles Prediction for Today’s Game

Based on recent trends the model predicts the Orioles will win Friday‘s MLB game with 65.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for White Sox players for Friday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Miguel Vargas has hit the Home Runs Over in 4 of his last 9 away games (+16.45 Units / 183% ROI)
  • Chase Meidroth has hit the Hits Over in 14 of his last 15 games (+12.30 Units / 44% ROI)
  • Chase Meidroth has hit the Singles Over in 13 of his last 15 games (+10.75 Units / 62% ROI)
  • Chase Meidroth has hit the Total Bases Over in 13 of his last 15 games (+10.75 Units / 42% ROI)
  • Edgar Quero has hit the Runs Under in his last 10 away games (+10.00 Units / 47% ROI)

And here are some favorite MLB player prop bets for Orioles players for Friday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Best Bets Today:

  • Dylan Carlson has hit the Home Runs Over in 2 of his last 4 games (+19.00 Units / 475% ROI)
  • Jackson Holliday has hit the Singles Over in 19 of his last 25 games (+11.85 Units / 37% ROI)
  • Jackson Holliday has hit the Hits Over in 18 of his last 25 games (+11.25 Units / 26% ROI)
  • Ryan O’Hearn has hit the Total Bases Over in 14 of his last 20 games at home (+8.65 Units / 30% ROI)
  • Dylan Carlson has hit the Runs Under in 13 of his last 15 games (+8.30 Units / 25% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 22 of their last 33 games (+11.25 Units / 31% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 15 of their last 32 games (+10.50 Units / 32% ROI)
  • The Chicago White Sox have hit the Team Total Under in 19 of their last 28 away games (+9.80 Units / 30% ROI)
  • The Chicago White Sox have covered the Run Line in 20 of their last 32 games (+7.10 Units / 19% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 17 of their last 26 away games (+6.75 Units / 21% ROI)
  • The Baltimore Orioles have hit the Team Total Under in 31 of their last 50 games (+9.60 Units / 16% ROI)
  • The Baltimore Orioles have hit the Game Total Over in 15 of their last 24 games at home (+7.35 Units / 28% ROI)
  • The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 6 of their last 7 games (+4.70 Units / 51% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 21 of their last 35 games (+4.39 Units / 10% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Moneyline in 5 of their last 7 games (+4.00 Units / 55% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 31-25 against the Run Line (+3.9 Units / 5.97% ROI).

  • 18-38 when betting on the Moneyline for -9.36 Units / -16.68% ROI
  • 26-27 when betting on the total runs Over for -3.75 Units / -6.09% ROI
  • 27-26 when betting on the total runs Under for -1.75 Units / -2.84% ROI

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 18-36 against the Run Line (-22.21 Units / -31.17% ROI).

  • 19-36 when betting on the Moneyline for -24.45 Units / -36.86% ROI
  • 27-25 when betting on the total runs Over for -0.13 Units / -0.22% ROI
  • 25-27 when betting on the total runs Under for -4.87 Units / -7.97% ROI

Orioles vs White Sox Home Run Prop Bets Today

Over Under
Gunnar Henderson (BAL) 0.5 +325 0.5 -450
Miguel Vargas (CWS) 0.5 +450 0.5 -650
Ryan O'Hearn (BAL) 0.5 +450 0.5 -650
Ryan Mountcastle (BAL) 0.5 +475 0.5 -650
Cedric Mullins (BAL) 0.5 +500 0.5 -700

Orioles vs White Sox Total Hits Prop Bets Today

Over Under
Jackson Holliday (BAL) 0.5 -250 0.5 +190
Ryan O'Hearn (BAL) 0.5 -250 0.5 +185
Adley Rutschman (BAL) 0.5 -250 0.5 +185
Gunnar Henderson (BAL) 0.5 -250 0.5 +195
Chase Meidroth (CWS) 0.5 -235 0.5 +175

Orioles vs White Sox RBI Prop Bets Today

Over Under
Gunnar Henderson (BAL) 0.5 +130 0.5 -175
Ryan Mountcastle (BAL) 0.5 +140 0.5 -190
Ryan O'Hearn (BAL) 0.5 +145 0.5 -200
Adley Rutschman (BAL) 0.5 +165 0.5 -220
Cedric Mullins (BAL) 0.5 +170 0.5 -225

Orioles vs White Sox Strikeout Prop Bets Today

Over Under
Jared Shuster (CWS) 1.5 +100 1.5 -135
Zach Eflin (BAL) 4.5 +130 4.5 -165

Sean Burke has walked 24% of batters when going through the lineup the first time in a game this month (5 games) — highest among among AL Starters; League Avg: 7% — first Percentile.

Sean Burke has walked 23% of left-handed batters this month (5 games) — highest among qualified SPs in MLB; League Avg: 8% — first Percentile.

Sean Burke has thrown his fastball for a strike just 55% (242/437) of the time this season — lowest in MLB among starting pitchers with at least 21 total IP; League Avg: 67% — 0 Percentile.

Sean Burke has walked 16% of batters this month (5 games) — tied for highest among qualified SPs in MLB; League Avg: 7% — first Percentile.

Orioles Starting Pitcher Stats & Trends

Zach Eflin walked 7 of 252 batters (3%) when going through the lineup the first time in a game in the 2024 season — 2nd best among qualified SPs in MLB; League Avg: 7% — 98th Percentile.

Zach Eflin allowed three-ball counts to 10% of batters they faced (35/350 PA’s) against right-handed batters in the 2024 season — lowest among qualified SPs in MLB; League Avg: 18% — 100th Percentile.

Zach Eflin walked 4% of batters in the 2024 season — tied for 2nd best among qualified SPs in MLB; League Avg: 7% — 98th Percentile.

Opponents batted .347 (60-for-173) against Zach Eflin when going through the lineup the third time in a game in the 2024 season — 2nd highest among qualified SPs in MLB; League Avg: .258 — third Percentile.

White Sox Keys to the Game vs. the Orioles

The White Sox are just 101-27 (.789) when leading entering the 8th inning since the 2023 season — lowest in MLB; League Avg: .900.

The White Sox are just 57-134 (.298) when allowing 5 or more extra base hits since last season — lowest in MLB; League Avg: .535.

The White Sox were just 40-103 (.280) when allowing 5 or more extra base hits in the 2024 season — lowest in MLB; League Avg: .538.

The White Sox are just 12-49 (.197) vs top 10 scoring offenses since last season They play the Orioles (fourth best runs scored) today.

Orioles Keys to the Game vs. the White Sox

The Orioles are just 4-15 (.211) after a win this season — 2nd lowest in MLB; League Avg: .512.

The Orioles are just 0-33 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .041.

The Orioles are just 18-29 (.383) when allowing 5 or more extra base hits this season — 3rd lowest in MLB; League Avg: .528.

The Orioles are just 3-20 (.130) when allowing 2 or more home runs this season — 5th lowest in MLB; League Avg: .288.

White Sox hitters have an OBP of just .285 (10,472 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .316.

White Sox hitters had an OBP of just .278 (5,869 PA’s) in the 2024 season — lowest in MLB; League Avg: .312.

The White Sox have a winning percentage of just 22% on the road since last season — lowest in MLB; League Avg: 47%.

The White Sox have a winning percentage of just 27% since last season — lowest in MLB; League Avg: 50%.

Orioles hitters have an OPS of just .550 (529 PA’s) against LHP this season — lowest in MLB; League Avg: .686.

Orioles hitters have put just 35% of balls in play to the left side of the field since the 2023 season — 2nd lowest in MLB; League Avg: 38%.

Orioles hitters are slugging just .152 on breaking pitches against LHP this season — lowest in MLB; League Avg: .339.

The Orioles have a winning percentage of just 35% at home this season — 3rd lowest in MLB; League Avg: 56%.

The White Sox have won just 17% of games in which their opponents scored first since the 2023 season — lowest in MLB; League Avg: 32%.

White Sox pitchers have won only 7% of games in which they have allowed their opponent to score in three different innings since last season — lowest in MLB; League Avg: 26%.

White Sox pitchers walked 643 of 6,241 batters (10%) in the 2024 season — highest in MLB; League Avg: 8%.

White Sox pitchers have walked 10% of batters since last season — highest in MLB; League Avg: 8%.

Orioles pitchers have walked 12% of batters when facing the leadoff batter in the inning this season — highest in MLB; League Avg: 8%.

Opponents have a miss rate of just 23% against Orioles pitchers this season — 3rd lowest in MLB; League Avg: 25%.

Orioles pitchers have allowed a slugging percentage of .481 this season — highest in MLB; League Avg: .394.

Orioles pitchers have an ERA of 6.17 (235.0 IP) at home this season — highest in MLB; League Avg: 3.83.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.