White Sox vs Red Sox Prediction, Odds & Player Prop Bets Today – MLB, Apr 20

Boston Red Sox third baseman Rafael Devers looks on during the eighth inning of a baseball game against the Baltimore Orioles, Sept. 29, 2023, in Baltimore. With the Red Sox ramping up at the start of spring training, Devers made it clear Tuesday, Feb. 20, 2024, that he felt the franchise should have done more to improve the roster over the winter.
AP Photo/Julio Cortez)
  • The Red Sox are -285 favorites vs the White Sox
  • White Sox vs Red Sox Over / Under today: 9 Runs
  • White Sox / Red Sox TV Channel: NESN | CHSN

The Chicago White Sox (+240) visit Fenway Park to take on the Boston Red Sox (-300) on Sunday, April 20, 2025. First pitch is scheduled for 1:35pm EDT in Boston, MA, MA.

This season, the White Sox are 4-16 against the spread (ATS), while the Red Sox are 11-11 ATS.

White Sox vs Red Sox Starting Pitchers Today:

  • White Sox starting pitcher: Sean Burke 1-3, 7.57 ERA
  • Red Sox starting pitcher: Tanner Houck 0-2, 9.17 ERA

White Sox vs. Red Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox+1.5 +110O 9.5 -118+240
Red Sox -1.5 -135U 9.5 -102-300

White Sox vs Red Sox Prediction for Today’s Game

Based on recent trends the model predicts the Red Sox will win Sunday‘s MLB game with 66.8% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for White Sox players for Sunday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Michael A. Taylor has hit the Hits Runs and RBIs Under in 9 of his last 10 games (+8.75 Units / 86% ROI)
  • Brooks Baldwin has hit the Singles Under in 15 of his last 20 away games (+8.20 Units / 27% ROI)
  • Brooks Baldwin has hit the Hits Under in 13 of his last 20 away games (+8.05 Units / 40% ROI)
  • Michael A. Taylor has hit the Total Bases Under in 9 of his last 10 games (+7.85 Units / 63% ROI)
  • Andrew Vaughn has hit the Runs Under in 12 of his last 15 games (+6.45 Units / 20% ROI)

And here are some favorite MLB player prop bets for Red Sox players for Sunday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Best Bets Today:

  • Trevor Story has hit the Singles Over in 15 of his last 20 games (+10.35 Units / 48% ROI)
  • Triston Casas has hit the Runs Under in his last 10 games (+10.00 Units / 49% ROI)
  • Trevor Story has hit the Hits Over in 13 of his last 15 games (+9.00 Units / 30% ROI)
  • Rafael Devers has hit the Total Bases Over in 8 of his last 9 games at home (+7.75 Units / 70% ROI)
  • Tanner Houck has hit the Walks Allowed Over in 14 of his last 20 games (+7.60 Units / 30% ROI)
  • The Chicago White Sox have hit the Team Total Under in 11 of their last 13 games (+8.80 Units / 54% ROI)
  • The Chicago White Sox have hit the Game Total Under in 8 of their last 12 games (+4.65 Units / 35% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Over in 83 of their last 159 games (+2.40 Units / 1% ROI)
  • The Boston Red Sox have hit the Team Total Under in 10 of their last 12 games (+7.20 Units / 45% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 10 of their last 17 games (+6.35 Units / 24% ROI)
  • The Boston Red Sox have hit the Game Total Under in 13 of their last 22 games (+4.35 Units / 18% ROI)
  • The Boston Red Sox have hit the Moneyline in 5 of their last 6 games (+4.25 Units / 38% ROI)
  • The Boston Red Sox have covered the 1st Five Innings (F5) Run Line in 4 of their last 5 games (+2.65 Units / 39% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 10-10 against the Run Line (-1.4 Units / -5.7% ROI).

  • 4-16 when betting on the Moneyline for -10.3 Units / -51.5% ROI
  • 8-10 when betting on the total runs Over for -2.95 Units / -13.5% ROI
  • 10-8 when betting on the total runs Under for +1.1 Units / 4.97% ROI

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 11-11 against the Run Line (-0.3 Units / -1.05% ROI).

  • 12-10 when betting on the Moneyline for -0.9 Units / -2.83% ROI
  • 8-13 when betting on the total runs Over for -6.05 Units / -25.1% ROI
  • 13-8 when betting on the total runs Under for +4.35 Units / 17.9% ROI

Red Sox vs White Sox Home Run Prop Bets Today

Over Under
Rafael Devers (BOS) 0.5 +260 0.5 -325
Wilyer Abreu (BOS) 0.5 +270 0.5 -325
Jarren Duran (BOS) 0.5 +400 0.5 -525
Triston Casas (BOS) 0.5 +450 0.5 -625
Alex Bregman (BOS) 0.5 +525 0.5 -750

Red Sox vs White Sox Total Hits Prop Bets Today

Over Under
Alex Bregman (BOS) 0.5 -250 0.5 +190
Ceddanne Rafaela (BOS) 0.5 -220 0.5 +170
Lenyn Sosa (CWS) 0.5 -210 0.5 +160
Rafael Devers (BOS) 0.5 -210 0.5 +160
Kristian Campbell (BOS) 0.5 -210 0.5 +155

Red Sox vs White Sox RBI Prop Bets Today

Over Under
Rafael Devers (BOS) 0.5 +120 0.5 -155
Wilyer Abreu (BOS) 0.5 +125 0.5 -160
Jarren Duran (BOS) 0.5 +130 0.5 -165
Alex Bregman (BOS) 0.5 +140 0.5 -190
Kristian Campbell (BOS) 0.5 +170 0.5 -225

Red Sox vs White Sox Strikeout Prop Bets Today

Over Under
Tanner Houck (BOS) 4.5 -160 4.5 +125
Sean Burke (CWS) 4.5 +105 4.5 -135

Sean Burke has allowed a slugging percentage of .857 (24 Total Bases / 28 ABs) against right-handed batters this month (3 games) — 2nd highest in MLB among starting pitchers with at least 6 total IP; League Avg: .385 — first Percentile.

Sean Burke has allowed a slugging percentage of .708 (34 Total Bases / 48 ABs) this month (3 games) — highest in MLB among starting pitchers with at least 6 total IP; League Avg: .394 — 0 Percentile.

Sean Burke has an ERA of 11.81 (10.2 IP)this month (3 games) — 2nd highest in MLB among starting pitchers with at least 6 total IP; League Avg: 3.96 — first Percentile.

Sean Burke has a strikeout rate of just 14% (3 SO in 21 PAs) on low non-fastballs this season — tied for 4th lowest in MLB among starting pitchers with at least 7 total IP; League Avg: 35% — fourth Percentile.

Red Sox Starting Pitcher Stats & Trends

Tanner Houck has allowed a .571 SLG this season — fourth worst among qualified SPs– third Percentile. He allowed a SLG of just .320 last season — fourth best among qualified SPs– 94th Percentile.

Opponents have a groundball rate of 55% (326/590) against Tanner Houck since last season — 5th highest among qualified SPs in MLB; League Avg: 43% — 92nd Percentile.

Left-handed hitters had a groundball rate of 58% (166/285) against Tanner Houck in the 2024 season — 3rd highest in MLB among starting pitchers with at least 64 total IP; League Avg: 42% — 97th Percentile.

Opponents had a groundball rate of 56% (293/524) against Tanner Houck in the 2024 season — 5th highest among qualified SPs in MLB; League Avg: 43% — 93rd Percentile.

White Sox Keys to the Game vs. the Red Sox

The White Sox were just 33-23 (.589) when leading entering the 7th inning in the 2024 season — lowest in MLB; League Avg: .856.

The White Sox are just 18-71 (.202) on the road since last season — lowest in MLB; League Avg: .468.

The White Sox were just 23-58 (.284) at home in the 2024 season — lowest in MLB; League Avg: .521.

The White Sox were just 8-36 (.182) vs top 10 scoring offenses in the 2024 season They play the Guardians (14th best runs scored) today.

Red Sox Keys to the Game vs. the White Sox

The Red Sox are 1-8 (.111) when trailing entering the 9th inning this season — tied for 4th best in MLB; League Avg: .032.

The Red Sox are just 0-8 (.000) when trailing entering the 7th inning this season — tied for lowest in MLB; League Avg: .110.

The Red Sox were just 17-33 (.340) vs top 10 scoring offenses in the 2024 season They play the Blue Jays (23rd best runs scored) today.

The Red Sox were just 18-69 (.207) when they scored 4 or fewer runs in the 2024 season — 4th lowest in MLB; League Avg: .276.

White Sox hitters have an OBP of just .277 (6,586 PA’s) since last season — lowest in MLB; League Avg: .312.

The White Sox had a winning percentage of just 22% on the road last season — lowest in MLB; League Avg: 48%.

The White Sox have a winning percentage of just 31% since the 2023 season — lowest in MLB; League Avg: 50%.

White Sox hitters had an OBP of just .278 (5,869 PA’s) in the 2024 season — lowest in MLB; League Avg: .312.

Red Sox hitters struck out 506 times in 1,816 PA’s (28%) against LHP in the 2024 season — highest in MLB; League Avg: 23%.

Red Sox hitters have chased 26% of pitches out of the zone against LHP this season — 3rd lowest in MLB; League Avg: 29%.

Red Sox hitters have struck out in 28% of it’s PA’s against LHP since last season — 2nd highest in MLB; League Avg: 23%.

Red Sox hitters have put just 26% of their swings in play on the first pitch of at-bats this season — lowest in MLB; League Avg: 35%.

The White Sox won just 11% of games in which their opponents scored first last season — lowest in MLB; League Avg: 31%.

White Sox pitchers won only 6% of games in which they allowed their opponent to score in three different innings last season — lowest in MLB; League Avg: 26%.

White Sox pitchers have walked 10% of batters since last season — highest in MLB; League Avg: 8%.

The White Sox won just 13% of home games in which their opponents scored first last season — lowest in MLB; League Avg: 35%.

Opponents have a miss rate of just 24% against Red Sox pitchers since last season — tied for 2nd lowest in MLB; League Avg: 25%.

Opponents have a groundball rate of 44% against Red Sox pitchers since the 2023 season — 5th highest in MLB; League Avg: 43%.

Red Sox pitchers have walked 8% of batters this season — 4th best in MLB; League Avg: 9%.

Opponents had a miss rate of just 24% against Red Sox pitchers in the 2024 season — tied for 2nd lowest in MLB; League Avg: 25%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.