Houston vs Duke Prediction, Odds & Best Bets Today – NCAAB, Apr. 5

Duke head coach Jon Scheyer watches from the sideline against North Carolina State during the first half of an NCAA college basketball game in Raleigh, N.C., Wednesday, Jan. 4, 2023.
(AP Photo/Karl B DeBlaker)
  • Duke is a -5.5 point favorite vs Houston
  • Total (Over/Under): 136.5 points
  • Houston / Duke TV channel: CBS

The Houston Cougars visit Alamodome to take on the Duke Blue Devils on Apr. 5. Tip off is scheduled for 8:49pm EDT in San Antonio, TX.

Duke is the betting favorite in this game, with the spread sitting at -5.5 (-105).

The Houston vs. Duke Over/Under is 136.5 total points.

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Houston vs. Duke Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Houston+5.5 -115O 136.5 -110+225
Duke -5.5 -105U 136.5 -110-275

Houston vs Duke Prediction for Today:

The winning team model predicts Duke will win this college basketball game with 51.0% confidence, based on game simulations, player injuries, key player performances and recent matchups.

Houston vs Duke Spread Prediction:

Based on recent against-the-spread trends, the spread model predicts Duke will cover the spread with 51.0% confidence for today’s game.


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  • Houston has hit the Moneyline in 30 of their last 31 games (+24.90 Units / 1% ROI)
  • Houston has hit the 1H Moneyline in 31 of their last 38 games (+12.60 Units / 1% ROI)
  • Houston has hit the Game Total Under in 22 of their last 36 games (+7.75 Units / 20% ROI)
  • Houston has hit the 1H Game Total Under in 7 of their last 9 games (+4.75 Units / 47% ROI)
  • Houston has hit the Team Total Over in 5 of their last 7 games (+3.85 Units / 47% ROI)
  • Duke has hit the Moneyline in 31 of their last 32 games (+28.40 Units / 2% ROI)
  • Duke have covered the 1H Spread in 19 of their last 25 games (+12.10 Units / 42% ROI)
  • Duke have covered the Spread in 25 of their last 38 games (+10.70 Units / 26% ROI)
  • Duke has hit the 1H Game Total Over in 16 of their last 23 games (+7.95 Units / 30% ROI)
  • Duke has hit the Team Total Over in 18 of their last 27 games (+7.75 Units / 25% ROI)

Houston Basketball Against the Spread Record (ATS)

Houston has a 21-16 record against the spread this college basketball season (+3.3 Units / 7.87% ROI).

  • 34-4 when betting on the Moneyline for +2.15 Units / 0.11% ROI
  • 14-23 when betting the Over for -11.4 Units / -27.18% ROI
  • 23-14 when betting the Under for +7.65 Units / 18.37% ROI

Duke Basketball Against the Spread Record (ATS)

Duke has a 25-13 record against the spread this college basketball season (+10.7 Units / 25.54% ROI).

  • 35-3 when betting on the Moneyline for +27.95 Units / 1.45% ROI
  • 20-18 when betting the Over for +0.2 Units / 0.48% ROI
  • 18-20 when betting the Under for -4 Units / -9.57% ROI

Houston Offensive Stats & Trends:

Houston averaged 9.0 turnovers per game (325 turnovers/36 games) last season — best among Big 12 Teams; League Avg: 11.8

Houston averaged 4.4 turnovers per game (158 turnovers/36 games) in the first half last season — best among Big 12 Teams; League Avg: 6.2

Houston has averaged 9.0 turnovers per game (342 turnovers/38 games) this season — tied for best among Power Conference teams; League Avg: 11.3

Houston is shooting 40% from three (310/781) this season — best among Power Conference teams; League Avg: 34%

Duke Offensive Stats & Trends:

Duke has an assist to turnover ratio of 1.8 (646 assists/ 356 TOs) this season — 3rd best among Division 1 Teams; League Avg: 1.2

Duke has an assist to turnover ratio of 1.9 (342 assists/ 177 TOs) in the first half this season — best among ACC Teams; League Avg: 1.2

Duke has attempted 1,202 threes at home since the start of the 2023-24 season — most among ACC Teams

Duke has an eFG% of 58% this season — best among Power Conference teams; League Avg: 52%

Houston Defensive Stats & Trends:

Houston averaged 9.9 steals per game (357 steals/36 games) last season — 2nd best among Power Conference teams; League Avg: 6.6

Houston averaged 9.9 steals per game (357 steals/36 games) last season — 8th best among Division 1 Teams; League Avg: 6.7

Houston allowed 57.5 points per game (2,070 points/36 games) last season — best among Big 12 Teams; League Avg: 69.0

Houston allowed 24.8 points per game (891 points/36 games) in the first half last season — best among Big 12 Teams; League Avg: 32.0

Duke Defensive Stats & Trends:

Duke has averaged 27.7 defensive rebounds per game (1,054 rebounds/38 games) this season — tied for 12th best among Division 1 Teams; League Avg: 24.2

Duke has allowed an average of 1.07 points per shot (2,378 points/2,225 shots) this season — tied for best among Division 1 Teams; League Avg: 1.24

Duke has allowed an average of 1.07 points per shot (2,378 points/2,225 shots) this season — best among ACC Teams; League Avg: 1.24

Duke has allowed an average of 1.11 points per shot (4,694 points/4,219 shots) since the start of the 2023-24 season — best among ACC Teams; League Avg: 1.22


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.