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Creighton has never made the Final Four.
The furthest Creighton has ever advanced in the NCAA Tournament was the Elite Eight, all the way back in 1941.
Creighton NCAA Tournament History
| Year | NCAA Tournament Result |
| 2021-22 | Lost NCAA Tournament Second Round |
| 2020-21 | Lost NCAA Tournament Regional Semifinal |
| 2017-18 | Lost NCAA Tournament First Round |
| 2016-17 | Lost NCAA Tournament First Round |
| 2013-14 | Lost NCAA Tournament Third Round |
| 2012-13 | Lost NCAA Tournament Third Round |
| 2011-12 | Lost NCAA Tournament Third Round |
| 2006-07 | Lost NCAA Tournament First Round |
| 2004-05 | Lost NCAA Tournament First Round |
| 2002-03 | Lost NCAA Tournament First Round |
| 2001-02 | Lost NCAA Tournament Second Round |
| 2000-01 | Lost NCAA Tournament First Round |
| 1999-00 | Lost NCAA Tournament First Round |
| 1998-99 | Lost NCAA Tournament Second Round |
| 1990-91 | Lost NCAA Tournament Second Round |
| 1988-89 | Lost NCAA Tournament First Round |
| 1980-81 | Lost NCAA Tournament First Round |
| 1977-78 | Lost NCAA Tournament First Round |
| 1974-75 | Lost NCAA Tournament First Round |
| 1973-74 | Lost NCAA Tournament Regional Semifinal |
| 1963-64 | Lost NCAA Tournament Regional Semifinal |
| 1961-62 | Lost NCAA Tournament Regional Semifinal |
| 1940-41 | Lost NCAA Tournament Regional Semifinal |
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