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The Sweet 16 for the 2023 NCAA Tournament will be played at four locations:
- T-Mobile Arena in Las Vegas
- Madison Square Garden in New York
- T-Mobile Center in Kansas City
- KFC YUM! Center in Louisville
2023 Sweet 16 Schedule
| Date | Matchup | Location |
|---|---|---|
| Thursday, March 23 | Michigan State vs. Kansas State | Madison Square Garden |
| Thursday, March 23 | Tennessee vs. FAU | Madison Square Garden |
| Thursday, March 23 | Arkansas vs. UConn | T-Mobile Arena |
| Thursday, March 23 | UCLA vs. Gonzaga | T-Mobile Arena |
| Friday, March 24 | Princeton vs. Creighton | KFC YUM! Center |
| Friday, March 24 | San Diego State vs. Alabama | KFC YUM! Center |
| Friday, March 24 | Xavier vs. Texas | T-Mobile Center |
| Friday, March 24 | Houston vs. Miami (FL) | T-Mobile Center |
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