Chargers vs Cardinals Prediction, Odds & Best Prop Bets – NFL, Week 7

• The Chargers are -3 point favorites vs the Cardinals
• Total (Over/Under): 43.5 points
• Watch this game on ESPN+

The Los Angeles Chargers (3-2-0) visit State Farm Stadium to take on the Arizona Cardinals (2-4-0) on Oct. 21. Kickoff is scheduled for 9:00pm EDT in Glendale, AZ.

The Chargers are betting favorites in this matchup, with the spread sitting at -3 (-105).

The Chargers vs. Cardinals Over/Under is 43.5 total points for the game.

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Chargers vs. Cardinals Odds, Spread, Over/Under

Chargers vs. Cardinals Prediction

The winning team model predicts the Chargers will win this game with 68.4% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Chargers vs Cardinals Spread Prediction

Based on recent against-the-spread trends, the model predicts the Chargers will cover the spread with 65.8% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.

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We’ve highlighted some favorite NFL player prop bets for Chargers players this playoff game, looking at profitable historical betting trends:

Best Chargers Player Prop Bets Today

• D.J. Chark has hit the Longest Reception Over in his last 7 games (+7.00 Units / 85% ROI)
• Hayden Hurst has hit the Receptions Under in his last 7 games (+7.00 Units / 62% ROI)
• Will Dissly has hit the Receiving Yards Over in 7 of his last 8 games (+5.95 Units / 63% ROI)
• Justin Herbert has hit the Passing Yards Under in 10 of his last 14 games (+5.25 Units / 30% ROI)
• J.K. Dobbins has hit the Carries Over in his last 5 games (+5.00 Units / 83% ROI)

And here are some top NFL player prop bets for Cardinals players for this matchup, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today

• Marvin Harrison Jr. has hit the Receptions Under in his last 6 games (+6.00 Units / 78% ROI)
• James Conner has hit the Longest Rush Over in his last 5 games (+5.00 Units / 85% ROI)
• Chris Moore has hit the Receiving Yards Over in 6 of his last 7 games (+4.85 Units / 58% ROI)
• James Conner has hit the Receiving Yards Under in 6 of his last 7 games at home (+4.75 Units / 54% ROI)
• Zay Jones has hit the Receptions Over in 5 of his last 6 games (+4.05 Units / 57% ROI)

Chargers Best Bets:

• The Los Angeles Chargers have hit the 3Q Game Total Under in 15 of their last 18 games (+12.25 Units / 57% ROI)
• The Los Angeles Chargers have hit the 1Q Moneyline in 6 of their last 10 away games (+4.35 Units / 35% ROI)
• The Los Angeles Chargers have covered the 1Q Spread in 7 of their last 10 away games (+3.80 Units / 31% ROI)
• The Los Angeles Chargers have hit the 1H Moneyline in 6 of their last 10 away games (+3.50 Units / 27% ROI)
• The Los Angeles Chargers have hit the 2H Moneyline in 3 of their last 5 games (+3.45 Units / 61% ROI)

Cardinals Best Bets:

• The Arizona Cardinals have hit the 2H Moneyline in 6 of their last 8 games (+7.10 Units / 89% ROI)
• The Arizona Cardinals have hit the 1H Game Total Over in 12 of their last 20 games (+4.05 Units / 18% ROI)
• The Arizona Cardinals have scored last in 4 of their last 5 games at home (+3.80 Units / 73% ROI)
• The Arizona Cardinals have covered the 2H Spread in 6 of their last 8 games (+3.70 Units / 42% ROI)
• The Arizona Cardinals have hit the 2Q Game Total Over in 10 of their last 16 games (+3.45 Units / 18% ROI)

Chargers Against the Spread (ATS) Record

Against the spread this NFL season, the Chargers art 3-1 (+1.9 Units / 34.55% ROI).

• Chargers are 3-2 when betting on the Moneyline for +1 Units / 13.7% ROI
• Chargers are 1-4 when betting the Over for -3.4 Units / -61.82% ROI
• Chargers are 4-1 when betting the Under for +2.9 Units / ROI

Cardinals Against the Spread (ATS) Record

Against the spread this NFL season, the Cardinals are 3-3 (-0.4 Units / -5.88% ROI).

• Cardinals are 2-4 when betting on the Moneyline for -0.9 Units / -13.14% ROI
• Cardinals are 3-2 when betting the Over for +0.8 Units / 12.12% ROI
• Cardinals are 2-3 when betting the Under for -1.3 Units / -19.7% ROI

Los Angeles Chargers: Keys to the Game vs. the Arizona Cardinals

Arizona Cardinals: Keys to the Game vs. the Los Angeles Chargers

Los Angeles Chargers Offense: Important Stats

Arizona Cardinals Offense: Important Stats

Los Angeles Chargers Defense: Important Stats

Arizona Cardinals Defense: Important Stats

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More NFL Betting Predictions:

• Anytime & First Touchdown Scorer Predictions
• Receiving Yards Prop Predictions
• Rushing Yards Prop Predictions
• Passing Yards Prop Predictions
• Receptions Made Prop Predictions
• Rushing Attempts Prop Predictions
• Passing Touchdowns Prop Predictions
• QB Interception Prop Predictions
• Field Goals Made Prop Predictions
• NFL Betting Previews: Every Game

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