Patriots vs Bills NFL Betting Odds, Lines & Predictions for Wild Card Weekend

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BetMGM Betting @BETMGM Jan 13, 2022, 11:09 AM
  • The Bills (10-6) are Patriots favorites vs the (10-6) Saturday, January 15, 2022 8:15pm EST
  • CBS on Broadcast Channel
  • Total (Over/Under): Total points

The Buffalo Bills (10-6) play the New England Patriots (10-6) on Saturday, January 15, 2022 8:15pm EST at Highmark Stadium in the Wild Card round of the NFL playoffs.

The Bills are betting favorites in this matchup, with the spread sitting at Favorite Team Spread (Favorite Spread Odds).

The total (Over/Under) is 44 points for the game.

Looking to place a bet on this game with a risk-free bet up to $1,000? Bet now on Bills vs Patriots and all NFL games with BetMGM

Where & How to Watch Buffalo Bills vs. New England Patriots, Wild Card Weekend

  • Game Day: Saturday, January 15, 2022
  • Game Time: 8:15pm EST
  • TV Channel: CBS
  • Location: Orchard Park, NY at Highmark Stadium

New England Patriots vs. Buffalo Bills Betting Odds & Spread, Wild Card Weekend

SpreadTotal (O/U)Moneyline
New England PatriotsAway Spread Away Spread OddsTotals Totals OddsAway Moneyline
Buffalo Bills Home Spread Home Spread OddsTotals Totals OddsHome Moneyline

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New England Patriots: Keys to the Game vs. the Buffalo Bills

The Patriots were 7-1 (.875) when not throwing an interception this season — tied for 5th-best in NFL; League Avg: .655.

The Patriots are winless (0-6) when rushing for less than 100 yards since last season — worst in NFL; League Avg: .317.

The Patriots are 3-11 (.214) when the opposing team converts 55% or more of its red zone chances into touchdowns since last season — 5th-worst in NFL; League Avg: .422.

The Patriots are winless (0-5) when rushing at least 4 yards less than 5 times in a game since last season — tied for worst in NFL; League Avg: .312.

Buffalo Bills: Keys to the Game vs. the New England Patriots

The Bills were winless (0-4) when within 7 points at the two minute warning this season — tied for worst in NFL; League Avg: .495.

The Bills were winless (0-4) when scoring less than 22 points this season — tied for worst in NFL; League Avg: .222.

The Bills were 9-1 (.900) when intercepting at least 1 pass this season — 3rd-best in NFL; League Avg: .633.

The Bills were winless (0-4) when allowing 22 or more points this season — tied for worst in NFL; League Avg: .267.

Additional Matchup Notes for New England Patriots vs. Buffalo Bills, Wild Card Weekend

Bills TEs had 58 receptions in 17 games (just 3.4 per game) this season — fourth-worst in NFL. The Patriots allowed just 2.8 receptions per game to TEs this season — best in NFL.

The Bills average 56.6 penalty yards per game since the 2020 season — tied for second-worst in NFL. The Patriots average 14.7 offensive penalty yards per game since last season — second-best in NFL.

Bills TEs had 58 receptions in 17 games (just 3.4 per game) this season — fourth-worst in NFL. The Patriots allowed just 2.8 receptions per game to TEs this season — best in NFL.

Patriots RBs averaged 2.3 yards after contact per carry this season — third-best in NFL. The Bills allowed 2.2 yards after contact per carry this season — tied for worst in NFL.

Patriots RBs averaged 2.3 yards after contact per carry this season — third-best in NFL. The Bills allowed 2.3 yards after contact per carry to RBs this season — tied for worst in NFL.

Patriots RBs had 22 rushing touchdowns in the Red Zone this season — most in NFL. The Bills allowed 19 rushing TDs this season — tied for fifth-most in NFL.

Key Injuries for the Buffalo Bills vs. New England Patriots Game, Wild Card Weekend

  • Star Lotulelei (Bills): Calf, Did Not Participate In Practice
  • Emmanuel Sanders (Bills): Foot, Limited Participation In Practice
  • Ronnie Perkins (Patriots): Shoulder, Limited Participation In Practice
  • Malcolm Perry (Patriots): Foot, Did Not Participate In Practice
  • Nelson Agholor (Patriots): Ankle, Limited Participation In Practice
  • Yodny Cajuste (Patriots): Hamstring, Limited Participation In Practice
  • Jalen Mills (Patriots): Ankle, Limited Participation In Practice

New England Patriots Offense: Important Stats for Wild Card Weekend

The Patriots threw the ball 27% of the time (15 Pass Attempts/56 plays) on 3rd and short last season — 2nd-lowest in NFL; League Avg: 47%

The Patriots started 4 drives inside their own 20 yard line in the 1st quarter this season — tied for fewest in NFL.

The Patriots averaged just 8.8 offensive penalty yards per game (140/16) last season — best in NFL; League Avg: 17.0

The Patriots threw the ball 45% of the time (440 Pass Attempts/979 plays) last season — 2nd-lowest in NFL; League Avg: 55%

Buffalo Bills Defense: Important Stats for Wild Card Weekend

The Bills had an average drive start position from the 37.0 yard line in the 1st quarter this season — best in NFL; League Avg: 25.7.

The Bills started 4 drives inside their own 20 yard line in the 1st quarter this season — tied for fewest in NFL.

The Bills ran 28% of their plays in the red zone in the 4th quarter this season — best in NFL; League Avg: 17%.

The Bills had an average drive start position from the 29.9 yard line this season — best in NFL; League Avg: 26.5.

New England Patriots Defense: Important Stats for Wild Card Weekend

The Patriots defense allowed a passer rating of just 73.4 (539 Pass Attempts) this season — 2nd-best in NFL; League Avg: 90.8.

The Patriots defense allowed a passer rating of just 33.7 on 3rd down (113 Pass Attempts) last season — best in NFL; League Avg: 85.7

The Patriots defense allowed a passer rating of just 28.6 on 3rd and long (56 Pass Attempts) last season — best in NFL; League Avg: 82.0

The Patriots defense allowed a Completion Pct of just 39% (11 completions/28 attempts) on third and 10+ yards to go last season — best in NFL; League Avg: 62%

Buffalo Bills Defense: Important Stats for Wild Card Weekend

The Bills defense allowed a passer rating of just 65.4 (531 Pass Attempts) this season — best in NFL; League Avg: 90.8.

The Bills defense sacked opposing QBs on 31% of pass attempts (9/29) in Week 18 — best in NFL; League Avg: 7%.

The Bills defense allowed 12 TD passes this season — fewest in NFL.

The Bills defense allowed a Completion Pct of just 56% (298 completions/531 attempts) this season — best in NFL; League Avg: 65%.

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.