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Cardinals World Series Odds

The Cardinals odds to win the World Series are +10000.

World Series Favorites

  • Los Angeles Dodgers: +240
  • New York Yankees: +800
  • Philadelphia Phillies: +1000

Cardinals Pennant Odds

The Cardinals odds to win the NL pennant are +5000.

NL Pennant Favorites

  • Los Angeles Dodgers: +135
  • Philadelphia Phillies: +600
  • New York Mets: +600

Cardinals Division Odds

The Cardinals NL Central champion odds are +850

NL Central Odds

  • Chicago Cubs: -125
  • Milwaukee Brewers: +280
  • Cincinnati Reds: +500
  • St. Louis Cardinals: +850
  • Pittsburgh Pirates: +3300

Cardinals Playoff Odds

The Cardinals odds to make the playoffs are +500. Their odds to miss the playoffs are -700.

Latest Stories

Astros vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Apr 14

The Houston Astros (-110) visit Busch Stadium to take on the St. Louis Cardinals (-110) on Monday, April 14, 2025. First pitch is scheduled for 7:45pm EDT in St. Louis, MO. This season, the Astros are Read More

BetMGM Betting Apr 14, 2025

Phillies vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Apr 13

The Philadelphia Phillies (-190) visit Busch Stadium to take on the St. Louis Cardinals (+160) on Sunday, April 13, 2025. First pitch is scheduled for 2:15pm EDT in St. Louis, MO. This season, the Phi Read More

BetMGM Betting Apr 13, 2025

Phillies vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Apr 12

The Philadelphia Phillies (-160) visit Busch Stadium to take on the St. Louis Cardinals (+135) on Saturday, April 12, 2025. First pitch is scheduled for 2:15pm EDT in St. Louis, MO. This season, the P Read More

BetMGM Betting Apr 12, 2025

Phillies vs Cardinals Prediction, Odds & Player Prop Bets Today – MLB, Apr 11

The Philadelphia Phillies (-125) visit Busch Stadium to take on the St. Louis Cardinals (+105) on Friday, April 11, 2025. First pitch is scheduled for 8:15pm EDT in St. Louis, MO. This season, the Phi Read More

BetMGM Betting Apr 11, 2025

Cardinals Payroll 2025: Total MLB Salary & Highest-Paid Players

Find out where the St. Louis Cardinals rank in MLB payroll and the highest-paid players on their team this season. Read More

Shane Jackson Apr 09, 2025

Cardinals vs Pirates Prediction, Odds & Player Prop Bets Today – MLB, Apr 9

The St. Louis Cardinals (-115) visit PNC Park to take on the Pittsburgh Pirates (-105) on Wednesday, April 9, 2025. First pitch is scheduled for 12:35pm EDT in Pittsburgh, PA. This season, the Cardina Read More

BetMGM Betting Apr 09, 2025

Cardinals Playoff Picture: Chances, Bracket, Seed for 2025

Where do the St. Louis Cardinals sit in the current MLB postseason bracket? Updated playoff odds and projected seed for the Cardinals. Read More

Shane Jackson Apr 08, 2025

Cardinals vs Pirates Prediction, Odds & Player Prop Bets Today – MLB, Apr 8

The St. Louis Cardinals (+115) visit PNC Park to take on the Pittsburgh Pirates (-135) on Tuesday, April 8, 2025. First pitch is scheduled for 6:40pm EDT in Pittsburgh, PA. This season, the Cardinals Read More

BetMGM Betting Apr 08, 2025

Cardinals vs Pirates Prediction, Odds & Player Prop Bets Today – MLB, Apr 7

The St. Louis Cardinals (-125) visit PNC Park to take on the Pittsburgh Pirates (+105) on Monday, April 7, 2025. First pitch is scheduled for 6:40pm EDT in Pittsburgh, PA. This season, the Cardinals a Read More

BetMGM Betting Apr 07, 2025
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Cardinals Odds Today

Apr 14 - 6 pm EST

Astros vs. Cardinals

How To Bet On St. Louis Cardinals Odds

Run lines, over/under totals, moneylines, and more odds are available for each Cardinals game this season.

  1. Visit the MLB betting page.
  2. Select odds for the Cardinals in a futures market (e.g., make the playoffs) or game market (e.g., Cardinals vs. the Reds)
  3. Add a bet to your Bet Slip.
  4. Add a Stake to see the potential payout.
  5. Place your bet!

If youโ€™re in Missouri and interested in odds for other teams, check out:ย 

St. Louis Cardinals Futures Odds

Will the Cardinals win the NL Central? Will they win the NL pennant? How many home runs will a certain player hit this season?

For example: If you bet $30 on the Cardinals (+600) to make the postseason, the bet would settle when St. Louis is eliminated or when they clinch a postseason berth.

St. Louis Cardinals Run Line

The run line is baseballโ€™s version of the spread. Whatโ€™s the final scoring margin of the game?

For example: If you bet $50 on the Cardinals -1.5 (+220) against the Pittsburgh Pirates, St. Louis must win the game by at least two runs.ย 

Alternatively, if you bet $10 on the Cardinals +1.5 (-130) against the Atlanta Braves, St. Louis must lose by one run (or win the game).

St. Louis Cardinals Moneyline

Will the Cardinals win the game?ย 

For example: If you bet $75 on the Cardinals -170 against the Texas Rangers, St. Louis must win the game (in nine innings or extra innings).

St. Louis Cardinals Over/Under Total

How many combined runs will be scored by both teams in the matchup?ย 

For example: If you bet $50 on over 8.5 (-105) in their game against the New York Mets, the teams must combine for at least nine runs.ย 

Alternatively, if you bet $60 on under 8.5 (-115), the teams must combine for eight or fewer runs.

If the combined run total is the same as the over/under total, the bet is a push.

St. Louis Cardinals Parlays

You can combine bets and other bets โ€” baseball or another sport โ€” into one parlay.

For example: If you bet $80 on a two-leg parlay with the Cardinals moneyline (-145) vs. the Boston Red Sox and over 8.5 (-110) in the Philadelphia Phillies-San Diego Padres game, both must hit for the bet to cash.

If one bet is a push, itโ€™s eliminated from the parlay, and odds (and payout) are recalculated without that leg.

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