Louisville vs Stanford Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 12

Stanford head coach Troy Taylor gestures during an NCAA college football game against UCLA, Saturday, Oct. 21, 2023, in Stanford, Calif. (AP Photo/Scot Tucker)
(AP Photo/Scot Tucker)
  • Louisville is a -20.5 point favorite vs. Stanford
  • Louisville vs. Stanford Total (Over/Under): 57.5 points
  • TV Channel: ACCN

The Louisville Cardinals (6-3) visit Stanford Stadium to take on the Stanford Cardinal (2-7) on Nov. 16 in Stanford, CA. Kickoff is scheduled for 3:30pm EST.

Louisville is a betting favorite in Week 12, with the spread sitting at -20.5 (-110).

The Louisville vs. Stanford Over/Under is 57.5 total points.

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Louisville vs. Stanford Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Louisville-20.5 -11057.5 -110-1400
Stanford +20.5 -11057.5 -110+825

Louisville vs Stanford Prediction:

The winning team model predicts Louisville will win this game with 92.3% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Louisville and Stanford, key player performances this season and recent team trends.

Louisville vs Stanford Spread Prediction:

Based on recent against-the-spread trends, the model predicts Louisville will cover the spread with 59.9% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • Louisville has hit the Game Total Over in 9 of their last 13 games (+4.60 Units / 32% ROI)
  • Louisville has hit the Moneyline in 4 of their last 7 away games (+2.15 Units / 19% ROI)
  • Louisville has hit the 1H Game Total Over in 7 of their last 13 games (+1.40 Units / 9% ROI)
  • Louisville has hit the 1Q Game Total Under in 4 of their last 7 away games (+0.30 Units / 4% ROI)
  • Stanford has hit the 1Q Game Total Over in 4 of their last 5 games at home (+3.05 Units / 59% ROI)
  • Stanford has hit the Game Total Under in 5 of their last 7 games at home (+2.80 Units / 36% ROI)
  • Stanford has hit the 1Q Moneyline in 1 of their last 4 games at home (+0.25 Units / 6% ROI)

We’ve highlighted some favorite college football player prop bets for Louisville players, looking at profitable historical betting trends:

Best Louisville Player Prop Bets Today

  • Isaac Brown has hit the Rushing Yards Over in his last 2 games (+2.00 Units / 83% ROI)
  • Chris Bell has hit the Receiving Yards Under in his last 2 games (+2.00 Units / 83% ROI)
  • Ja’Corey Brooks has hit the Receiving Yards Over in 3 of his last 4 games (+1.80 Units / 38% ROI)
  • Ja’Corey Brooks has hit the Receptions Over in his last game (+1.15 Units / 115% ROI)
  • Chris Bell has hit the Receptions Under in his last game (+1.00 Units / 80% ROI)

Top NCAAF player prop bets for Stanford players, looking at profitable historical betting trends:

Best Stanford Player Prop Best Bets Today

  • Sam Roush has hit the Receiving Yards Over in his last game (+1.00 Units / 95% ROI)
  • Ismael Cisse has hit the Receiving Yards Over in his last game (+1.00 Units / 87% ROI)
  • Ashton Daniels has hit the Passing Yards Under in his last game (+1.00 Units / 83% ROI)
  • Tiger Bachmeier has hit the Receiving Yards Under in his last game (+1.00 Units / 74% ROI)
  • Ashton Daniels has hit the TD Passes Under in his last game (+1.00 Units / 65% ROI)

Louisville Against the Spread (ATS) Record

Louisville is 4-5 against the spread this college football season (-1.55 Units / -15.58% ROI).

  • Louisville is 5-3 when betting on the Moneyline for +2.6 Units / 3.24% ROI
  • Louisville is 6-3 when betting the Over for +2.7 Units / 27.27% ROI
  • Louisville is 3-6 when betting the Under for -3.6 Units / -36.36% ROI

Stanford Against the Spread (ATS) Record

Stanford is 2-6 against the spread this college football season (-4.6 Units / -46.7% ROI).

  • Stanford is 1-7 when betting on the Moneyline for -4 Units / -50% ROI
  • Stanford is 3-6 when betting the Over for -3.6 Units / -36.36% ROI
  • Stanford is 6-3 when betting the Under for +2.7 Units / 27.27% ROI

Louisville: Keys to the Game vs. Stanford

Louisville is 11-5 (.688) when the opposing team rushes more than 30 times since the 2023 season– T-15th-best among Power Conference Teams; Average: .490

Louisville is 13-6 (.684) when committing less than 60 yards in penalties since the 2023 season– 28th-best in FBS; Average: .528

Louisville is 16-5 (.762) when allowing less than 50% of third down conversion opportunities since the 2023 season– 25th-best in FBS; Average: .608

Louisville is 9-5 (.643) when sacking the QB less than 3 times since the 2023 season– T-21st-best in FBS; Average: .429

Stanford: Keys to the Game vs. Louisville

Stanford is winless (0-7) when allowing 10 or more rushes of four or more yards this season– worst among Power Conference Teams; Average: .540

Stanford is 2-11 (.154) when the opposing team commits less than 60 yards in penalties since the 2023 season– worst among Power Conference Teams; Average: .590

Stanford is 1-16 (.059) when allowing 10 or more rushes of four or more yards since the 2023 season– worst among Power Conference Teams; Average: .530

Stanford is 5-13 (.278) when rushing more than 30 times since the 2023 season– worst among Power Conference Teams; Average: .671

Matchup Notes for Louisville vs. Stanford

Stanford has gained 1,579 yards on 160 receptions (just 9.9 YPR) this season — T-3rd-worst among FBS skill players. Louisville’s defense has allowed just 10.9 Yards Per Reception this season — T-32nd-best among FBS defenses.

Stanford’s offense has thrown for 20 or more yards on just 6.0% of 266 attempts this season — 2nd-worst among FBS offenses. Louisville’s defense allowed 20+ yards on just 8.1% of attempts this season — 3rd-best among ACC defenses.

Stanford’s offense has thrown for 20 or more yards on just 6.0% of 266 attempts this season — 2nd-worst among FBS offenses. Louisville’s defense allowed 20+ yards on just 8.1% of attempts this season — T-35th-best among FBS defenses.

Louisville’s offense has thrown for 2,578 passing yards in 9 games (286.4 YPG) this season — T-16th-best among FBS offenses. Stanford’s defense has allowed 268.1 passing yards per game this season — 8th-worst among FBS defenses.

Louisville’s offense has thrown for 20 or more yards on 12.3% of 316 attempts this season — T-31st-best among FBS offenses. Stanford’s defense allowed 20+ yards on 11.1% of attempts this season — 4th-worst among ACC defenses.

Louisville’s QBs has thrown for 2,578 passing yards in 9 games (286.4 YPG) this season — T-16th-best among FBS teams. Stanford’s defense has allowed 268.1 passing yards per game this season — 8th-worst among FBS defenses.

Louisville Offensive Stats & Trends

Louisville’s offense has thrown for 2,578 passing yards in 9 games (286.4 YPG) this season — T-16th-best among FBS offenses. Stanford’s defense has allowed 268.1 passing yards per game this season — 8th-worst among FBS defenses.

Louisville’s offense has thrown for 20 or more yards on 12.3% of 316 attempts this season — T-31st-best among FBS offenses. Stanford’s defense allowed 20+ yards on 11.1% of attempts this season — 4th-worst among ACC defenses.

Louisville’s QBs has thrown for 2,578 passing yards in 9 games (286.4 YPG) this season — T-16th-best among FBS teams. Stanford’s defense has allowed 268.1 passing yards per game this season — 8th-worst among FBS defenses.

Louisville TEs have picked up first downs on 7 receptions in close and late situations this season– T-most among FBS Teams

Louisville WRs have averaged 23.3 yards per reception (303 yards/13 catches) on 3rd and long this season– 5th-best among Power Conference Teams; Average: 14.7

Stanford Offensive Stats & Trends

Stanford has gained 1,579 yards on 160 receptions (just 9.9 YPR) this season — T-3rd-worst among FBS skill players. Louisville’s defense has allowed just 10.9 Yards Per Reception this season — T-32nd-best among FBS defenses.

Stanford’s offense has thrown for 20 or more yards on just 6.0% of 266 attempts this season — 2nd-worst among FBS offenses. Louisville’s defense allowed 20+ yards on just 8.1% of attempts this season — 3rd-best among ACC defenses.

Stanford RBs have not rushed for a 0 TD on 17 carries (inf Carries Per TD) in the Red Zone this season– worst Carries Per TD among FBS Teams; Average: 4.4

Stanford RBs have averaged 13.6 carries per game (286 carries / 21 games) since the 2023 season– 2nd-lowest among FBS Teams; Average: 24.9

Stanford RBs have rushed for 3 TDs on 37 carries (12.3 Carries Per TD) in the Red Zone since the 2023 season– 3rd-worst Carries Per TD among FBS Teams; Average: 4.6

Louisville Cardinals Defensive Stats & Trends

Louisville has intercepted 2 of 297 attempts (148.5 pass attempts per int.) this season– 2nd-worst in FBS; Average: 36.1

Louisville has intercepted 2 of 297 attempts (148.5 pass attempts per int.) this season– 2nd-worst among Power Conference Teams; Average: 34.2

Louisville has allowed 6.5 touchdowns per interception (13 TDs allowed, and 2 INT) this season– T-2nd-worst among Power Conference Teams; Average: 1.5

Louisville has allowed 6.5 touchdowns per interception (13 TDs allowed, and 2 INT) this season– T-8th-worst in FBS; Average: 1.7

Louisville has tackled opponents for a loss on just 3 of 46 rushing attempts (7% TFL%) in the Red Zone this season– 8th-worst in FBS; Average: 15%.

Stanford Cardinal Defensive Stats & Trends

Stanford has allowed 31 TD passes in the Red Zone since the 2023 season– most among Power Conference Teams

Stanford has not recorded a sack (37 pass attempts) in the Red Zone this season– T-worst in FBS; Average: 15.1

Stanford has not recorded a sack (37 pass attempts) in the Red Zone this season– T-worst among Power Conference Teams; Average: 15.9

Stanford has allowed 55 TD passes since the 2023 season– most in FBS

Stanford has allowed 55 TD passes since the 2023 season– most among Power Conference Teams


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.