Angels vs Astros Prediction, Odds & Player Prop Bets Today – MLB, Sep 22

Houston Astros' Jose Altuve bats during the first inning of a baseball game against the Texas Rangers, Wednesday, July 26, 2023, in Houston.
(AP Photo/Kevin M. Cox)
  • The Astros are -275 favorites vs the Angels
  • Angels vs Astros Over / Under today: 8 Runs
  • Angels / Astros TV Channel: SCHN | BSW

The Los Angeles Angels (+220) visit Minute Maid Park to take on the Houston Astros (-275) on Sunday, September 22, 2024. First pitch is scheduled for 2:10pm EDT in Houston, TX.

This season, the Angels are against the spread (ATS), while the Astros are ATS.

Angels vs Astros Starting Pitchers Today:

  • Angels starting pitcher: Griffin Canning 6-13, 5.19 ERA
  • Astros starting pitcher: Spencer Arrighetti 7-13, 4.74 ERA

Angels vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Angels+1.5 +110O 8 -105+220
Astros -1.5 -135U 8 -115-275

Angels vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Astros will win Sunday‘s MLB game with 71.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Angels players for Sunday‘s game, looking at profitable historical betting trends:

Best Angels Player Prop Bets Today:

  • Taylor Ward has hit the Home Runs Over in 9 of his last 26 games (+26.10 Units / 100% ROI)
  • Taylor Ward has hit the Total Bases Over in 30 of his last 49 games (+15.55 Units / 26% ROI)
  • Taylor Ward has hit the Hits Over in 33 of his last 44 games (+14.50 Units / 16% ROI)
  • Zach Neto has hit the Singles Under in 31 of his last 45 games (+12.65 Units / 20% ROI)
  • Taylor Ward has hit the Runs Over in 17 of his last 26 games (+11.10 Units / 42% ROI)

And here are some favorite MLB player prop bets for Astros players for Sunday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Yainer Diaz has hit the Hits Over in 16 of his last 25 games at home (+16.65 Units / 55% ROI)
  • Jeremy Pena has hit the Home Runs Over in 6 of his last 38 games (+11.80 Units / 31% ROI)
  • Yainer Diaz has hit the Hits Runs and RBIs Over in 15 of his last 18 games at home (+11.50 Units / 48% ROI)
  • Yainer Diaz has hit the Total Bases Over in 17 of his last 25 games at home (+11.00 Units / 43% ROI)
  • Yainer Diaz has hit the Runs Over in 15 of his last 24 games at home (+10.20 Units / 42% ROI)
  • The Los Angeles Angels have hit the 1st Five Innings (F5) Team Total Over in 15 of their last 21 games (+8.55 Units / 33% ROI)
  • The Los Angeles Angels have hit the Game Total Under in 51 of their last 96 games (+7.40 Units / 7% ROI)
  • The Houston Astros have covered the 1st Five Innings (F5) Run Line in their last 49 games (+49.00 Units / 74% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Moneyline in their last 49 games (+49.00 Units / 49% ROI)
  • The Houston Astros have hit the Game Total Under in 80 of their last 137 games (+20.15 Units / 13% ROI)
  • The Houston Astros have covered the Run Line in 56 of their last 96 games (+18.85 Units / 16% ROI)
  • The Houston Astros have hit the Moneyline in 51 of their last 81 games (+12.00 Units / 10% ROI)

Angels Against the Spread (ATS) Record

Against the spread this season, the Angels are against the Run Line ( Units / ROI).

  • away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • away total over record when betting on the total runs Over for over units Units / over ROI ROI
  • away total under record when betting on the total runs Under for under units Units / under ROI ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are against the Run Line ( Units / ROI).

  • home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • home total over record when betting on the total runs Over for over units Units / over ROI ROI
  • home total under record when betting on the total runs Under for under units Units / under ROI ROI

Astros vs Angels Home Run Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +250 0.5 -350
Kyle Tucker (HOU) 0.5 +400 0.5 -550
Zach Neto (LAA) 0.5 +500 0.5 -700
Yainer Diaz (HOU) 0.5 +500 0.5 -700
Alex Bregman (HOU) 0.5 +500 0.5 -700

Astros vs Angels Total Hits Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 -250 0.5 +190
Alex Bregman (HOU) 0.5 -250 0.5 +185
Taylor Ward (LAA) 0.5 -190 0.5 +145
Mauricio Dubon (HOU) 0.5 -185 0.5 +140
Kyle Tucker (HOU) 0.5 -185 0.5 +140

Astros vs Angels RBI Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +130 0.5 -165
Alex Bregman (HOU) 0.5 +130 0.5 -175
Yainer Diaz (HOU) 0.5 +145 0.5 -190
Jeremy Pena (HOU) 0.5 +145 0.5 -190
Kyle Tucker (HOU) 0.5 +155 0.5 -200

Astros vs Angels Strikeout Prop Bets Today

Over Under
Griffin Canning (LAA) 3.5 -155 3.5 +115
Spencer Arrighetti (HOU) 6.5 -110 6.5 -115

Griffin Canning has allowed a slugging percentage of .559 (137 Total Bases / 245 ABs) when going through the lineup the first time in a game this season — highest among qualified SPs in MLB; League Avg: .382 — first Percentile.

Griffin Canning has allowed an OPS of .901 (270 PA’s) when going through the lineup the first time in a game this season — highest among qualified SPs in MLB; League Avg: .670 — first Percentile.

Griffin Canning has allowed an OPS of .627 (349 PA’s) with two-strikes this season — 4th highest among qualified SPs in MLB; League Avg: .486 — sixth Percentile.

Griffin Canning has an ERA of 5.93 (68.1 IP) on the road this season — 2nd highest among qualified SPs in MLB; League Avg: 3.89 — third Percentile.

Astros Starting Pitcher Stats & Trends

Opponents have a line drive rate of 29% (109/370) against Spencer Arrighetti since last season — 2nd highest in MLB among starting pitchers with at least 126 total IP; League Avg: 24% — first Percentile.

Spencer Arrighetti has allowed an OBP of .430 (230 PA’s) versus the top of the order this season — highest in MLB among starting pitchers with at least 61 total IP; League Avg: .322 — 0 Percentile.

Spencer Arrighetti has allowed a slugging percentage of .622 (122 Total Bases / 196 ABs) versus the top of the order this season — 2nd highest in MLB among starting pitchers with at least 61 total IP; League Avg: .435 — first Percentile.

Spencer Arrighetti has allowed a slugging percentage of .673 (33 Total Bases / 49 ABs) on low fastballs this season — tied for 3rd highest in MLB among starting pitchers with at least 61 total IP; League Avg: .403 — third Percentile.

Angels Keys to the Game vs. the Astros

The Angels are just 41-47 (.466) after a loss as favorites since the 2022 season — lowest in MLB; League Avg: .589.

The Angels are just 116-12 (.906) when leading entering the 9th inning since the 2023 season — 3rd lowest in MLB; League Avg: .949.

The Angels are just 26-123 (.174) when allowing 10 or more hits since the 2022 season — 3rd lowest in MLB; League Avg: .265.

The Angels are just 105-18 (.854) when leading entering the 8th inning since the 2023 season — 3rd lowest in MLB; League Avg: .900.

Astros Keys to the Game vs. the Angels

The Astros are just 0-53 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .050.

The Astros are just 4-10 (.286) after a loss as underdogs this season — 2nd lowest in MLB; League Avg: .434.

The Astros are 81-58 (.583) after a road win since the 2022 season — best in MLB; League Avg: .484.

The Astros are just 12-22 (.353) when tied entering the 8th inning since the 2023 season — tied for 2nd lowest in MLB; League Avg: .500.

The Angels have scored first in just 26% of their home games this season — lowest in MLB; League Avg: 44%.

Angels hitters have an OBP of just .279 (1,383 PA’s) against pitchers who have thrown at least 80 pitches in a game since the 2022 season — lowest in MLB; League Avg: .317.

The Angels have a winning percentage of just 41% at home this season — 3rd lowest in MLB; League Avg: 52%.

The Angels have scored first in just 29% of their games against division opponents this season — lowest in MLB; League Avg: 50%.

Astros hitters are averaging just 3.64 pitches per plate appearance against RHP this season — lowest in MLB; League Avg: 3.89.

14% of Astros’ hitters plate appearances have lasted only one pitch (2,565/18,187 PA’s) since the 2022 season — highest in MLB; League Avg: 11%.

Astros hitters have just 958 strikeouts in 5,288 PA’s (18%) against LHP since the 2022 season — best in MLB; League Avg: 22%.

Astros hitters are averaging just 3.75 pitches per plate appearance against RHP since the 2022 season — lowest in MLB; League Avg: 3.90.

Angels pitchers have walked 405 of 4,248 batters (10%) when facing the leadoff batter in the inning since the 2022 season — highest in MLB; League Avg: 8%.

Angels pitchers have walked 576 of 5,868 batters (10%) this season — 2nd highest in MLB; League Avg: 8%.

The Angels pitchers have allowed their opponents to score first in 74% of their games at home this season — highest in MLB; League Avg: 56%.

Angels pitchers have walked 133 of 1,374 batters (10%) when facing the leadoff batter in the inning this season — highest in MLB; League Avg: 7%.

Opponents have a miss rate of 28% against Astros pitchers since the 2022 season — 2nd best in MLB; League Avg: 26%.

Astros pitchers have an ERA of 3.52 (2097.1 IP) on the road since the 2022 season — best in MLB; League Avg: 4.26.

The average home run distance against the Astros pitchers since last season is 392.3 feet — best in MLB; League Avg: 398.4

Astros pitchers have a strikeout rate of 24% since last season — 4th best in MLB; League Avg: 23%.

Astros vs. Angels Injuries Tonight That May Affect Prop Bets 

  • Houston Astros – No Injuries Reported
  • Los Angeles Angels – No Injuries Reported

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.