Blue Jays vs Astros Prediction, Odds & Player Prop Bets Today – MLB, Apr 23

Houston Astros' Jose Altuve bats during the first inning of a spring training baseball game against the St. Louis Cardinals, Monday, March 6, 2023, in Jupiter, Fla. (AP Photo/Lynne Sladky)
(AP Photo/Lynne Sladky)
  • The Blue Jays are -105 favorites vs the Astros
  • Blue Jays vs Astros Over / Under today: 8.5 Runs
  • Blue Jays / Astros TV Channel: RSN1 | MLBN | SCH2

The Toronto Blue Jays (-105) visit Daikin Park to take on the Houston Astros (-115) on Wednesday, April 23, 2025. First pitch is scheduled for 7:40pm EDT in Houston, TX, TX.

This season, the Blue Jays are 12-12 against the spread (ATS), while the Astros are 13-10 ATS.

Blue Jays vs Astros Starting Pitchers Today:

  • Blue Jays starting pitcher: Bowden Francis 2-2, 3.23 ERA
  • Astros starting pitcher: Ryan Gusto 2-1, 3.18 ERA

Blue Jays vs. Astros Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Blue Jays-1.5 +155O 8.5 -110-105
Astros +1.5 -190U 8.5 -110-115

Blue Jays vs Astros Prediction for Today’s Game

Based on recent trends the model predicts the Blue Jays will win Wednesday‘s MLB game with 51.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Blue Jays players for Wednesday‘s game, looking at profitable historical betting trends:

Best Blue Jays Player Prop Bets Today:

  • Andres Gimenez has hit the Hits Under in 10 of his last 15 games (+11.00 Units / 73% ROI)
  • Ernie Clement has hit the Total Bases Under in 12 of his last 15 games (+10.10 Units / 44% ROI)
  • Ernie Clement has hit the Hits Runs and RBIs Under in 12 of his last 15 games (+8.25 Units / 43% ROI)
  • Nathan Lukes has hit the Home Runs Over in 1 of his last 4 away games (+8.00 Units / 200% ROI)
  • Bo Bichette has hit the Runs Under in 15 of his last 20 games (+7.20 Units / 26% ROI)

And here are some favorite MLB player prop bets for Astros players for Wednesday‘s game, looking at profitable historical betting trends:

Best Astros Player Prop Best Bets Today:

  • Isaac Paredes has hit the Home Runs Over in 4 of his last 8 games at home (+19.40 Units / 242% ROI)
  • Yordan Alvarez has hit the Runs Under in 16 of his last 20 games (+11.45 Units / 46% ROI)
  • Christian Walker has hit the RBIs Under in 21 of his last 25 games (+11.25 Units / 21% ROI)
  • Jeremy Pena has hit the Hits Over in his last 8 games at home (+8.00 Units / 44% ROI)
  • Christian Walker has hit the Hits Runs and RBIs Under in 17 of his last 25 games (+7.40 Units / 25% ROI)
  • The Toronto Blue Jays have hit the Game Total Under in 15 of their last 21 games (+8.45 Units / 36% ROI)
  • The Toronto Blue Jays have covered the Run Line in 16 of their last 23 games (+7.20 Units / 21% ROI)
  • The Toronto Blue Jays have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 11 away games (+5.30 Units / 44% ROI)
  • The Toronto Blue Jays have covered the 1st Five Innings (F5) Run Line in 14 of their last 21 games (+5.25 Units / 19% ROI)
  • The Toronto Blue Jays have hit the Team Total Under in 5 of their last 6 games (+4.00 Units / 54% ROI)
  • The Houston Astros have covered the Run Line in 11 of their last 15 games (+8.90 Units / 45% ROI)
  • The Houston Astros have hit the Team Total Under in 15 of their last 23 games (+6.25 Units / 23% ROI)
  • The Houston Astros have hit the Game Total Under in 6 of their last 7 games (+4.80 Units / 60% ROI)
  • The Houston Astros have hit the 1st Five Innings (F5) Team Total Over in 7 of their last 9 games at home (+4.65 Units / 42% ROI)
  • The Houston Astros have hit the Moneyline in 5 of their last 6 games at home (+3.80 Units / 48% ROI)

Blue Jays Against the Spread (ATS) Record

Against the spread this season, the Blue Jays are 16-8 against the Run Line (+6.2 Units / 17.34% ROI).

  • 12-12 when betting on the Moneyline for +0.6 Units / 2.21% ROI
  • 9-15 when betting on the total runs Over for -7.05 Units / -27.06% ROI
  • 15-9 when betting on the total runs Under for +5.2 Units / 19.44% ROI

Astros Against the Spread (ATS) Record

Against the spread this season, the Astros are 13-10 against the Run Line (+4.25 Units / 14.03% ROI).

  • 12-11 when betting on the Moneyline for -1.25 Units / -4.39% ROI
  • 8-13 when betting on the total runs Over for -6.25 Units / -24.75% ROI
  • 13-8 when betting on the total runs Under for +4.15 Units / 16.37% ROI

Astros vs Blue Jays Home Run Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 +260 0.5 -325
Christian Walker (HOU) 0.5 +275 0.5 -350
Anthony Santander (TOR) 0.5 +310 0.5 -400
Yainer Diaz (HOU) 0.5 +450 0.5 -650
Isaac Paredes (HOU) 0.5 +450 0.5 -625

Astros vs Blue Jays Total Hits Prop Bets Today

Over Under
Yordan Alvarez (HOU) 0.5 -220 0.5 +165
Jose Altuve (HOU) 0.5 -220 0.5 +165
Jeremy Pena (HOU) 0.5 -210 0.5 +155
Andres Gimenez (TOR) 0.5 -210 0.5 +160
Anthony Santander (TOR) 0.5 -200 0.5 +150

Astros vs Blue Jays RBI Prop Bets Today

Over Under
Anthony Santander (TOR) 0.5 +140 0.5 -185
Christian Walker (HOU) 0.5 +140 0.5 -190
Yordan Alvarez (HOU) 0.5 +150 0.5 -200
Vladimir Guerrero Jr. (TOR) 0.5 +170 0.5 -225
Jeremy Pena (HOU) 0.5 +180 0.5 -235

Astros vs Blue Jays Strikeout Prop Bets Today

Over Under
Bowden Francis (TOR) 4.5 -110 4.5 -118
Ryan Gusto (HOU) 3.5 +100 3.5 -135

Opponents are hitting just .094 (3-for-32) against Bowden Francis when going through the lineup the first time in a game this season — best among among AL Starters; League Avg: .231 — 100th Percentile.

Opponents are hitting just .146 (23-for-157) against Bowden Francis when going through the lineup the second time in a game since last season — 2nd best in MLB among starting pitchers with at least 73 total IP; League Avg: .244 — 99th Percentile.

Opponents have a miss rate of just 10% (3/29) against Bowden Francis on the first pitch of at-bats this season — tied for 4th lowest among qualified SPs in MLB; League Avg: 25% — sixth Percentile.

Bowden Francis allowed a BABIP of .212 in the 2024 season — tied for best in MLB among starting pitchers with at least 64 total IP; League Avg: .289 — 100th Percentile.

Astros Starting Pitcher Stats & Trends

Ryan Gusto has a strike rate of 72% (182/251) this season — highest in MLB among starting pitchers with at least 8 total IP; League Avg: 64% — 100th Percentile.

Ryan Gusto has thrown fastballs 74% of the time (45/61) with runners in scoring position this season — 2nd highest in MLB among starting pitchers with at least 8 total IP; League Avg: 43% — 99th Percentile.

Ryan Gusto has a strike rate of 75% (122/163) against right-handed batters this season — highest in MLB among starting pitchers with at least 8 total IP; League Avg: 65% — 100th Percentile.

Ryan Gusto has allowed three-ball counts to 9% of batters they faced (6/69 PA’s) this season — 3rd lowest in MLB among starting pitchers with at least 8 total IP; League Avg: 20% — 98th Percentile.

Blue Jays Keys to the Game vs. the Astros

The Blue Jays were just 6-73 (.076) when trailing entering the 7th inning in the 2024 season — 2nd lowest in MLB; League Avg: .143.

The Blue Jays are 28-15 (.651) when tied entering the 7th inning since the 2023 season — best in MLB; League Avg: .499.

The Blue Jays were just 17-75 (.185) when they scored 4 or fewer runs in the 2024 season — 2nd lowest in MLB; League Avg: .276.

The Blue Jays are 8-4 (.667) when tied entering the 8th inning since last season — 5th best in MLB; League Avg: .500.

Astros Keys to the Game vs. the Blue Jays

The Astros were just 0-56 (.000) when trailing entering the 9th inning in the 2024 season — tied for lowest in MLB; League Avg: .050.

The Astros are just 13-23 (.361) when tied entering the 8th inning since the 2023 season — 3rd lowest in MLB; League Avg: .500.

The Astros are just 2-9 (.182) after a win this season — 3rd lowest in MLB; League Avg: .481.

The Astros are just 6-13 (.316) when tied entering the 8th inning since last season — 3rd lowest in MLB; League Avg: .500.

The Blue Jays are batting just .183 on the first pitch of at-bats this season — lowest in MLB; League Avg: .344.

Blue Jays hitters have an OBP of .392 (192 PA’s) against LHP this season — best in MLB; League Avg: .308.

Blue Jays hitters have struck out in 46% of it’s PA’s against LHP over the past seven days (3 games) — highest in MLB; League Avg: 23%.

Blue Jays hitters are slugging just .288 on the first pitch of at-bats this season — lowest in MLB; League Avg: .583.

Astros hitters averaged just 3.65 pitches per plate appearance against RHP in the 2024 season — lowest in MLB; League Avg: 3.89.

Astros hitters averaged just 3.66 pitches per plate appearance in the 2024 season — lowest in MLB; League Avg: 3.89.

Astros hitters are averaging just 3.68 pitches per plate appearance against RHP since last season — lowest in MLB; League Avg: 3.89.

Astros hitters struck out just 324 times in 1,678 PA’s (19%) against LHP in the 2024 season — 2nd best in MLB; League Avg: 23%.

Opponents have a groundball batting average of just .045 against Blue Jays pitchers with the shift this season — best in MLB; League Avg: .235.

Opponents had a miss rate of just 24% against Blue Jays pitchers in the 2024 season — tied for 2nd lowest in MLB; League Avg: 25%.

Batters facing the Blue Jays pitchers have struck out in the zone 47% of the time since last season — 3rd lowest in MLB; League Avg: 50%. since last season — 3rd lowest in MLB; League Avg: 50%.

Opponents have a groundball rate of just 41% against Blue Jays pitchers since the 2023 season — 5th lowest in MLB; League Avg: 43%.

Opponents have a miss rate of 28% against Astros pitchers since last season — 2nd best in MLB; League Avg: 25%.

Opponents have a miss rate of 28% against Astros pitchers this season — best in MLB; League Avg: 26%.

Astros pitchers walked 544 of 6,019 batters (9%) in the 2024 season — 4th highest in MLB; League Avg: 8%.

Opponents had a miss rate of 28% against Astros pitchers in 2023 — 3rd best in MLB; League Avg: 26%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.