- The Cardinals are -150 favorites vs the White Sox
- Cardinals vs White Sox Over / Under today: 8 Runs
- Cardinals / White Sox TV Channel: FDMW | CHSN
The St. Louis Cardinals (-150) visit Rate Field to take on the Chicago White Sox (+125) on Tuesday, June 17, 2025. First pitch is scheduled for 7:40pm EDT in Chicago, IL.
This season, the Cardinals are 37-35 against the spread (ATS), while the White Sox are 42-30 ATS.
Cardinals vs White Sox Starting Pitchers Today:
- Cardinals starting pitcher: Matthew Liberatore 3-6, 4.18 ERA
- White Sox starting pitcher: Shane Smith 3-3, 2.35 ERA
Cardinals vs. White Sox Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| Cardinals | -1.5 +115 | O 8.5 -105 | -150 |
| White Sox | +1.5 -140 | U 8.5 -115 | +125 |
Cardinals vs White Sox Prediction for Today’s Game
Based on recent trends the model predicts the Cardinals will win Tuesday‘s MLB game with 58.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
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We’ve highlighted some favorite MLB player prop bets for Cardinals players for Tuesday‘s game, looking at profitable historical betting trends:
Best Cardinals Player Prop Bets Today:
- Alec Burleson has hit the Total Bases Over in 20 of his last 25 games (+17.20 Units / 49% ROI)
- Willson Contreras has hit the RBIs Over in 12 of his last 15 games (+15.40 Units / 103% ROI)
- Ivan Herrera has hit the Runs Under in 16 of his last 20 games (+9.70 Units / 29% ROI)
- Nolan Gorman has hit the Home Runs Over in 3 of his last 9 games (+9.00 Units / 100% ROI)
- Lars Nootbaar has hit the Hits Runs and RBIs Under in his last 8 games (+8.00 Units / 80% ROI)
And here are some favorite MLB player prop bets for White Sox players for Tuesday‘s game, looking at profitable historical betting trends:
Best White Sox Player Prop Best Bets Today:
- Chase Meidroth has hit the Total Bases Over in 19 of his last 25 games at home (+11.70 Units / 30% ROI)
- Chase Meidroth has hit the Hits Runs and RBIs Over in 18 of his last 25 games at home (+11.65 Units / 41% ROI)
- Chase Meidroth has hit the Singles Over in 18 of his last 25 games at home (+11.45 Units / 40% ROI)
- Chase Meidroth has hit the Hits Over in 20 of his last 25 games at home (+11.45 Units / 26% ROI)
- Mike Tauchman has hit the Home Runs Over in 3 of his last 10 games at home (+10.60 Units / 106% ROI)
Cardinals Best Bets Today:
- The St. Louis Cardinals have covered the Run Line in 25 of their last 39 games (+11.95 Units / 23% ROI)
- The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 22 of their last 35 away games (+7.31 Units / 17% ROI)
- The St. Louis Cardinals have hit the Moneyline in 28 of their last 49 games (+6.95 Units / 12% ROI)
- The St. Louis Cardinals have hit the Team Total Under in 9 of their last 12 away games (+5.95 Units / 43% ROI)
- The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 14 of their last 22 away games (+5.80 Units / 23% ROI)
White Sox Best Bets Today:
- The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 25 of their last 34 games at home (+15.10 Units / 37% ROI)
- The Chicago White Sox have covered the Run Line in 31 of their last 48 games (+11.20 Units / 19% ROI)
- The Chicago White Sox have hit the Team Total Over in 16 of their last 21 games at home (+10.90 Units / 45% ROI)
- The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 16 of their last 34 games at home (+10.60 Units / 30% ROI)
- The Chicago White Sox have hit the Moneyline in 12 of their last 20 games at home (+8.79 Units / 44% ROI)
Cardinals Against the Spread (ATS) Record
Against the spread this season, the Cardinals are 40-32 against the Run Line (+3.15 Units / 3.19% ROI).
- 37-35 when betting on the Moneyline for +1.3 Units / 1.59% ROI
- 38-31 when betting on the total runs Over for +3.8 Units / 4.8% ROI
- 31-38 when betting on the total runs Under for -10.95 Units / -13.82% ROI
White Sox Against the Spread (ATS) Record
Against the spread this season, the White Sox are 42-30 against the Run Line (+8 Units / 9.28% ROI).
- 23-49 when betting on the Moneyline for -13.46 Units / -18.67% ROI
- 33-36 when betting on the total runs Over for -6.75 Units / -8.52% ROI
- 36-33 when betting on the total runs Under for -0.5 Units / -0.63% ROI
White Sox vs Cardinals Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Willson Contreras (STL) | 0.5 +375 | 0.5 -500 |
| Nolan Gorman (STL) | 0.5 +400 | 0.5 -525 |
| Miguel Vargas (CWS) | 0.5 +400 | 0.5 -525 |
| Luis Robert (CWS) | 0.5 +400 | 0.5 -550 |
| Alec Burleson (STL) | 0.5 +425 | 0.5 -600 |
White Sox vs Cardinals Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Chase Meidroth (CWS) | 0.5 -275 | 0.5 +200 |
| Edgar Quero (CWS) | 0.5 -275 | 0.5 +200 |
| Nolan Arenado (STL) | 0.5 -235 | 0.5 +180 |
| Willson Contreras (STL) | 0.5 -235 | 0.5 +180 |
| Miguel Vargas (CWS) | 0.5 -220 | 0.5 +165 |
White Sox vs Cardinals RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Willson Contreras (STL) | 0.5 +135 | 0.5 -185 |
| Alec Burleson (STL) | 0.5 +140 | 0.5 -185 |
| Ivan Herrera (STL) | 0.5 +155 | 0.5 -200 |
| Edgar Quero (CWS) | 0.5 +155 | 0.5 -210 |
| Nolan Arenado (STL) | 0.5 +160 | 0.5 -220 |
White Sox vs Cardinals Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Matthew Liberatore (STL) | 4.5 -145 | 4.5 +110 |
| Shane Smith (CWS) | 4.5 +110 | 4.5 -140 |
Cardinals Starting Pitcher Stats & Trends
Opposing hitters have a chase rate of 39% (36/92) against Matthew Liberatore when he’s behind in the count this season — highest among qualified SPs in MLB; League Avg: 25% — 100th Percentile.
Matthew Liberatore has walked 2% of batters when going through the lineup the second time in a game this season — 2nd best among qualified SPs in MLB; League Avg: 7% — 98th Percentile.
Matthew Liberatore has walked 2% of right-handed batters this season — 2nd best among qualified SPs in MLB; League Avg: 7% — 98th Percentile.
Matthew Liberatore has walked 4% of batters this season — 3rd best among qualified SPs in MLB; League Avg: 7% — 97th Percentile.
White Sox Starting Pitcher Stats & Trends
Opponents are hitting .333 (5-for-15) against Shane Smith when going through the lineup the second time in a game in his last two starts — tied for 6th highest in MLB over the last two weeks; League Avg: .236 — 12th Percentile.
Opponents have a chase percentage of just 18% (60/331) against Shane Smith in non-two strike counts this season — 5th lowest in MLB among starting pitchers with at least 28 total IP; League Avg: 23% — third Percentile.
Shane Smith has allowed a slugging percentage of just .265 (27 Total Bases / 102 ABs) when going through the lineup the first time in a game this season — 10th best in MLB among starting pitchers with at least 28 total IP; League Avg: .385 — 92nd Percentile.
Shane Smith has allowed a slugging percentage of just .312 (78 Total Bases / 250 ABs) this season — tied for 14th best in MLB among starting pitchers with at least 28 total IP; League Avg: .399 — 91st Percentile.
Cardinals Keys to the Game vs. the White Sox
The Cardinals are just 11-169 (.061) when trailing entering the 8th inning since the 2023 season — 4th lowest in MLB; League Avg: .099.
The Cardinals are 32-1 (.970) when leading entering the 8th inning this season — 2nd best in MLB; League Avg: .903.
The Cardinals are 23-14 (.622) when tied entering the 7th inning since last season — 4th best in MLB; League Avg: .499.
The Cardinals are just 0-29 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .045.
White Sox Keys to the Game vs. the Cardinals
The White Sox are just 41-128 (.243) after a loss since last season — lowest in MLB; League Avg: .499.
The White Sox are just 4-80 (.048) when allowing 10 or more hits since last season — lowest in MLB; League Avg: .253.
The White Sox are just 18-44 (.290) when tied entering the 7th inning since the 2023 season — lowest in MLB; League Avg: .499.
The White Sox are just 104-27 (.794) when leading entering the 8th inning since the 2023 season — tied for lowest in MLB; League Avg: .900.
Cardinals Hitting Stats & Trends
Cardinals hitters struck out just 351 times in 1,755 PA’s (20%) against LHP in the 2024 season — tied for 5th best in MLB; League Avg: 23%.
The Cardinals are batting .162 on pitches out of the zone since the 2023 season — tied for 2nd best in MLB; League Avg: .150.
The Cardinals batted .248 with two outs in the 2024 season — 4th best in MLB; League Avg: .234.
The Cardinals are batting .255 this season — tied for 3rd best in MLB; League Avg: .245.
White Sox Hitting Stats & Trends
The White Sox have a winning percentage of just 21% on the road since last season — lowest in MLB; League Avg: 47%.
White Sox hitters have an OBP of just .286 (10,952 PA’s) against RHP since the 2023 season — lowest in MLB; League Avg: .316.
White Sox hitters are slugging just .334 against RHP this season — lowest in MLB; League Avg: .402.
The White Sox have a winning percentage of just 27% since last season — lowest in MLB; League Avg: 50%.
Cardinals Pitching Stats & Trends
Opponents have a miss rate of just 22% against Cardinals pitchers this season — lowest in MLB; League Avg: 25%.
Cardinals pitchers had a strikeout rate of just 38% with two-strikes in 2023 — tied for 2nd lowest in MLB; League Avg: 43%.
Opponents have a miss rate of just 23% against Cardinals pitchers since the 2023 season — 2nd lowest in MLB; League Avg: 25%.
Cardinals pitchers have walked 7% of batters this season — tied for best in MLB; League Avg: 9%.
White Sox Pitching Stats & Trends
White Sox pitchers walked 643 of 6,241 batters (10%) in the 2024 season — highest in MLB; League Avg: 8%.
The White Sox have won just 17% of games in which their opponents scored first since the 2023 season — lowest in MLB; League Avg: 32%.
The White Sox have won just 6% of road games in which their opponents scored first since last season — lowest in MLB; League Avg: 26%.
White Sox pitchers have won only 7% of games in which they have allowed their opponent to score in three different innings since last season — lowest in MLB; League Avg: 26%.
More MLB Reading:
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