Cubs vs Padres Prediction, Odds & Player Prop Bets Today – MLB, Apr 10

San Diego Padres' Jake Cronenworth during a baseball game against the San Francisco Giants in San Francisco, Wednesday, June 21, 2023.
(AP Photo/Jeff Chiu)
  • The Padres are -145 favorites vs the Cubs
  • Cubs vs Padres Over / Under today: 8 Runs
  • Cubs / Padres TV Channel: MARQ | PDTV

The Chicago Cubs (+120) visit Petco Park to take on the San Diego Padres (-145) on Wednesday, April 10, 2024. First pitch is scheduled for 6:40pm EDT in San Diego, CA.

This season, the Cubs are 7-4 against the spread (ATS), while the Padres are 6-8 ATS.

Cubs vs Padres Starting Pitchers Today:

  • Cubs starting pitcher: Kyle Hendricks 0-1, 11.75 ERA
  • Padres starting pitcher: Dylan Cease 0-1, 3.38 ERA

Cubs vs. Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cubs+1.5 -165O 8 -105+120
Padres -1.5 +140U 8 -115-145

Cubs vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Wednesday‘s MLB game with 54.5% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Cubs players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Bets Today:

  • Seiya Suzuki has hit the Hits Over in 38 of his last 50 games (+18.70 Units / 17% ROI)
  • Seiya Suzuki has hit the Hits Runs and RBIs Over in 35 of his last 50 games (+16.85 Units / 27% ROI)
  • Seiya Suzuki has hit the Total Bases Over in 32 of his last 50 games (+16.15 Units / 27% ROI)
  • Christopher Morel has hit the Hits Over in 10 of his last 11 games (+8.55 Units / 42% ROI)
  • Christopher Morel has hit the Total Bases Over in 9 of his last 11 games (+7.40 Units / 46% ROI)

And here are some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

  • Jake Cronenworth has hit the Total Bases Over in 31 of his last 45 games (+19.00 Units / 31% ROI)
  • Xander Bogaerts has hit the Total Bases Over in 26 of his last 40 games (+16.45 Units / 32% ROI)
  • Xander Bogaerts has hit the Hits Runs and RBIs Over in 29 of his last 40 games (+15.50 Units / 30% ROI)
  • Fernando Tatis Jr. has hit the Hits Runs and RBIs Under in 18 of his last 25 games (+10.95 Units / 34% ROI)
  • Xander Bogaerts has hit the Hits Over in 28 of his last 40 games (+10.95 Units / 14% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 38 of their last 66 games (+9.21 Units / 12% ROI)
  • The Chicago Cubs have hit the Game Total Under in 21 of their last 32 games (+8.75 Units / 25% ROI)
  • The Chicago Cubs have hit the Moneyline in 57 of their last 100 games (+5.95 Units / 5% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Moneyline in 3 of their last 6 games (+0.05 Units / 1% ROI)
  • The San Diego Padres have hit the Game Total Under in 82 of their last 152 games (+16.85 Units / 10% ROI)
  • The San Diego Padres have covered the Run Line in 31 of their last 55 games at home (+12.50 Units / 21% ROI)
  • The San Diego Padres have hit the Moneyline in 20 of their last 27 games (+12.45 Units / 30% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 12 of their last 16 games (+8.80 Units / 33% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 12 of their last 16 games (+7.09 Units / 36% ROI)

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 8-3 against the Run Line (+4.1 Units / 25.71% ROI).

  • 7-4 when betting on the Moneyline for +3.9 Units / 27.08% ROI
  • 7-4 when betting on the total runs Over for +2.7 Units / 22.31% ROI
  • 4-7 when betting on the total runs Under for -3.6 Units / -29.75% ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 6-8 against the Run Line (-0.38 Units / -2.42% ROI).

  • 6-8 when betting on the Moneyline for -3.21 Units / -18.29% ROI
  • 6-7 when betting on the total runs Over for -1.53 Units / -9.92% ROI
  • 7-6 when betting on the total runs Under for +0.4 Units / 2.58% ROI

Padres vs Cubs Home Run Prop Bets Today

Over Under
Tatis Jr. 0.5 +425 0.5 -650
Bellinger 0.5 +475 0.5 -700
Morel 0.5 +500 0.5 -700
Machado 0.5 +525 0.5 -750
Happ 0.5 +575 0.5 -900

Padres vs Cubs Total Hits Prop Bets Today

Over Under
Machado 0.5 -275 0.5 +200
Bogaerts 0.5 -275 0.5 +210
Campusano 0.5 -225 0.5 +170
Cronenworth 0.5 -210 0.5 +160
Bellinger 0.5 -200 0.5 +150

Padres vs Cubs RBI Prop Bets Today

Over Under
Machado 0.5 +140 0.5 -190
Tatis Jr. 0.5 +145 0.5 -200
Cronenworth 0.5 +170 0.5 -225
Bellinger 0.5 +180 0.5 -250
Morel 0.5 +195 0.5 -275

Padres vs Cubs Strikeout Prop Bets Today

Over Under
Cease 7.5 +110 7.5 -150
Hendricks 3.5 +135 3.5 -175

Kyle Hendricks has located his pitches away 73% of the time (895/1,224) vs left-handed batters since last season — highest in MLB among starting pitchers with at least 68 total IP; League Avg: 45% — 100th Percentile.

Kyle Hendricks has allowed a slugging percentage of 1.037 (28 Total Bases / 27 ABs) on pitches in the strike zone this season — highest in MLB among starting pitchers with at least 3 total IP; League Avg: .448 — 0 Percentile.

Kyle Hendricks has averaged 87.6 MPH on fastballs in the 2023 season — lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 93.5 — first Percentile.

Kyle Hendricks located 73% of his pitches away (827/1,135) vs left-handed batters in the 2023 season — highest in MLB among starting pitchers with at least 64 total IP; League Avg: 45% — 100th Percentile.

Padres Starting Pitcher Stats & Trends

Right-handed batters are hitting just .050 (1-for-20) against Dylan Cease this season — best among in MLB; League Avg: .239 — 100th Percentile.

Opponents have a groundball rate of just 27% (7/26) against Dylan Cease this season — lowest among in MLB; League Avg: 44% — first Percentile.

Dylan Cease has thrown breaking pitches 59% of the time (1,001/1,681) against right-handed batters since last season — highest among in MLB; League Avg: 34% — 100th Percentile.

Right-handed batters are hitting just .050 (1-for-20) against Dylan Cease this season — 3rd best among qualified SPs in MLB; League Avg: .236 — 97th Percentile.

Cubs Keys to the Game vs. the Padres

The Cubs were just 7-12 (.368) when tied entering the 7th inning in 2023 — 5th lowest in MLB; League Avg: .500.

The Cubs are just 11-24 (.314) after a win as underdogs since the 2023 season — 4th lowest in MLB; League Avg: .428.

The Cubs are just 33-38 (.465) after a loss as favorites since the 2022 season — 3rd lowest in MLB; League Avg: .587.

The Cubs are 20-17 (.541) after a loss as underdogs since the 2023 season — 5th best in MLB; League Avg: .420.

Padres Keys to the Game vs. the Cubs

The Padres are just 3-15 (.167) after a win as underdogs since the 2023 season — lowest in MLB; League Avg: .428.

The Padres were just 2-13 (.133) after a win as underdogs in 2023 — lowest in MLB; League Avg: .430.

The Padres are just 1-73 (.014) when trailing entering the 9th inning since the 2023 season — 3rd lowest in MLB; League Avg: .051.

The Padres are just 15-30 (.333) after a win as underdogs since the 2022 season — 2nd lowest in MLB; League Avg: .415.

The Cubs are batting .474 when facing the starting pitcher for the 3rd time in a game this season — best in MLB; League Avg: .258.

Cubs hitters have an OBP of .565 (23 PA’s) when facing the starting pitcher for the 3rd time in a game this season — best in MLB; League Avg: .325.

Cubs hitters slugged .509 in lefty-lefty matchups in the 2023 season — 2nd best in MLB; League Avg: .376.

Cubs hitters have an OPS of .833 (81 PA’s) against LHP this season — 4th best in MLB; League Avg: .710.

Padres hitters have a swing rate of just 44% against LHP since last season — lowest in MLB; League Avg: 48%.

Padres hitters had an OPS of .808 (1,699 PA’s) against LHP in the 2023 season — 3rd best in MLB; League Avg: .742.

Padres hitters have a swing rate of just 46% against LHP since the 2022 season — lowest in MLB; League Avg: 48%.

Padres hitters are slugging .466 against LHP since last season — 3rd best in MLB; League Avg: .417.

Cubs pitchers have a strikeout rate of 28% with runners in scoring position this season — 2nd best in MLB; League Avg: 21%.

Cubs pitchers have a strikeout rate of 26% this season — 5th best in MLB; League Avg: 23%.

Opponents had a groundball batting average of just .220 against Cubs pitchers in the 2023 season — 2nd best in MLB; League Avg: .248.

The Cubs pitchers have allowed their opponents to score first in just 45% of their games since the 2022 season — 5th lowest in MLB; League Avg: 50%.

Padres pitchers have a strikeout rate of just 15% in close and late situations this season — lowest in MLB; League Avg: 25%.

Opponents have a groundball rate of 45% against Padres pitchers since last season — tied for 3rd highest in MLB; League Avg: 43%.

Padres pitchers allowed an average Exit Velocity of 87.9 MPH (3,921 batted balls) in the 2023 season — best in MLB; League Avg: 89.0.

Padres pitchers had an ERA of 3.43 (735.0 IP) at home in the 2023 season — 2nd best in MLB; League Avg: 4.23.

Padres vs. Cubs Injuries Tonight That May Affect Prop Bets 

  • Glenn Otto (San Diego Padres): Shoulder, 15-Day IL
  • Reiss Knehr (San Diego Padres): Elbow, Out
  • Drew Carlton (San Diego Padres): Elbow, Out
  • Luis Patino (San Diego Padres): Elbow, 15-Day IL
  • Tucupita Marcano (San Diego Padres): Knee, 10-Day IL
  • Patrick Wisdom (Chicago Cubs): Back, 10-Day IL
  • Justin Steele (Chicago Cubs): Hamstring, 15-Day IL
  • Brennen Davis (Chicago Cubs): Undisclosed, Out
  • Tyler Duffey (Chicago Cubs): Back, Day-To-Day
  • Jameson Taillon (Chicago Cubs): Back, 15-Day IL
  • Caleb Kilian (Chicago Cubs): Shoulder, 60-Day IL

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.