Guardians vs Giants Prediction, Odds & Player Prop Bets Today – MLB, Jun 17

San Francisco Giants' Wilmer Flores (41) throws to first against the Los Angeles Dodgers during a baseball game in San Francisco, Friday, Sept. 29, 2023. (AP Photo/Jed Jacobsohn)
(AP Photo/Jed Jacobsohn)
  • The Giants are -160 favorites vs the Guardians
  • Guardians vs Giants Over / Under today: 7 Runs
  • Guardians / Giants TV Channel: GDTV | NSBA

The Cleveland Guardians (+135) visit Oracle Park to take on the San Francisco Giants (-160) on Tuesday, June 17, 2025. First pitch is scheduled for 9:45pm EDT in San Francisco, CA.

This season, the Guardians are 35-35 against the spread (ATS), while the Giants are 34-38 ATS.

Guardians vs Giants Starting Pitchers Today:

  • Guardians starting pitcher: Slade Cecconi 1-3, 4.32 ERA
  • Giants starting pitcher: Robbie Ray 8-1, 2.57 ERA

Guardians vs. Giants Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians+1.5 -175O 7 +100+135
Giants -1.5 +145U 7 -120-160

Guardians vs Giants Prediction for Today’s Game

Based on recent trends the model predicts the Giants will win Tuesday‘s MLB game with 58.7% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Tuesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Angel Martinez has hit the Home Runs Over in 2 of his last 8 away games (+12.00 Units / 150% ROI)
  • Bo Naylor has hit the Hits Runs and RBIs Under in 11 of his last 15 games (+7.85 Units / 45% ROI)
  • Jose Ramirez has hit the Singles Over in 14 of his last 20 games (+7.60 Units / 34% ROI)
  • Carlos Santana has hit the Hits Over in 9 of his last 10 away games (+7.50 Units / 51% ROI)
  • Carlos Santana has hit the Total Bases Over in 9 of his last 10 away games (+7.50 Units / 51% ROI)

And here are some favorite MLB player prop bets for Giants players for Tuesday‘s game, looking at profitable historical betting trends:

Best Giants Player Prop Best Bets Today:

  • Casey Schmitt has hit the Home Runs Over in 3 of his last 6 games (+13.40 Units / 223% ROI)
  • Willy Adames has hit the Hits Under in 17 of his last 25 games (+13.00 Units / 46% ROI)
  • Tyler Fitzgerald has hit the Runs Under in 18 of his last 20 games (+12.95 Units / 32% ROI)
  • Willy Adames has hit the Singles Under in 17 of his last 20 games at home (+12.85 Units / 43% ROI)
  • Tyler Fitzgerald has hit the Hits Runs and RBIs Under in 16 of his last 20 games (+12.05 Units / 45% ROI)
  • The Cleveland Guardians have hit the Team Total Under in 39 of their last 67 games (+8.29 Units / 11% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 20 of their last 33 games (+7.90 Units / 21% ROI)
  • The Cleveland Guardians have hit the Moneyline in 32 of their last 61 games (+3.60 Units / 5% ROI)
  • The Cleveland Guardians have covered the Run Line in 8 of their last 12 away games (+3.00 Units / 16% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 19 games (+2.50 Units / 11% ROI)
  • The San Francisco Giants have hit the Game Total Under in 18 of their last 27 games (+10.05 Units / 33% ROI)
  • The San Francisco Giants have hit the Team Total Under in 32 of their last 53 games (+9.05 Units / 15% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Team Total Under in 19 of their last 30 games at home (+7.00 Units / 20% ROI)
  • The San Francisco Giants have hit the Moneyline in their last 5 games at home (+5.40 Units / 96% ROI)
  • The San Francisco Giants have hit the 1st Five Innings (F5) Moneyline in 10 of their last 19 games at home (+3.30 Units / 10% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 36-34 against the Run Line (-4.25 Units / -4.34% ROI).

  • 35-35 when betting on the Moneyline for +0.45 Units / 0.56% ROI
  • 31-35 when betting on the total runs Over for -6.35 Units / -8.38% ROI
  • 35-31 when betting on the total runs Under for +1 Units / 1.28% ROI

Giants Against the Spread (ATS) Record

Against the spread this season, the Giants are 34-38 against the Run Line (-3.25 Units / -3.58% ROI).

  • 41-31 when betting on the Moneyline for +2.6 Units / 2.61% ROI
  • 33-36 when betting on the total runs Over for -6.2 Units / -7.91% ROI
  • 36-33 when betting on the total runs Under for -1 Units / -1.25% ROI

Giants vs Guardians Home Run Prop Bets Today

Over Under
Jose Ramirez (CLE) 0.5 +450 0.5 -650
Willy Adames (SF) 0.5 +475 0.5 -700
Mike Yastrzemski (SF) 0.5 +550 0.5 -800
Heliot Ramos (SF) 0.5 +550 0.5 -800
Lane Thomas (CLE) 0.5 +625 0.5 -1000

Giants vs Guardians Total Hits Prop Bets Today

Over Under
Heliot Ramos (SF) 0.5 -275 0.5 +200
Steven Kwan (CLE) 0.5 -250 0.5 +190
Rafael Devers (SF) 0.5 -250 0.5 +185
Jose Ramirez (CLE) 0.5 -250 0.5 +195
Willy Adames (SF) 0.5 -190 0.5 +145

Giants vs Guardians RBI Prop Bets Today

Over Under
Rafael Devers (SF) 0.5 +125 0.5 -160
Jose Ramirez (CLE) 0.5 +135 0.5 -185
Willy Adames (SF) 0.5 +175 0.5 -235
Heliot Ramos (SF) 0.5 +190 0.5 -250
David Fry (CLE) 0.5 +195 0.5 -275

Giants vs Guardians Strikeout Prop Bets Today

Over Under
Robbie Ray (SF) 6.5 -110 6.5 -120
Slade Cecconi (ARI) 4.5 +115 4.5 -150

Opponents had a groundball batting average of .345 (29 GB hits out of 84 GBs) against Slade Cecconi in the 2024 season — 3rd highest in MLB among starting pitchers with at least 64 total IP; League Avg: .245 — first Percentile.

Slade Cecconi had an ERA of 6.66 (77.0 IP)in the 2024 season — 3rd highest in MLB among starting pitchers with at least 64 total IP; League Avg: 3.97 — first Percentile.

Slade Cecconi allowed a slugging percentage of .527 (165 Total Bases / 313 ABs) in the 2024 season — 6th highest in MLB among starting pitchers with at least 64 total IP; League Avg: .404 — third Percentile.

Slade Cecconi walked 5% of batters in the 2024 season — tied for 15th best in MLB among starting pitchers with at least 64 total IP; League Avg: 7% — 91st Percentile.

Giants Starting Pitcher Stats & Trends

Opponents are hitting just .177 (20-for-113) against Robbie Ray when going through the lineup the second time in a game this season — 7th best among qualified SPs in MLB; League Avg: .237 — 92nd Percentile.

Opponents are hitting just .199 (58-for-291) against Robbie Ray this season — 10th best among qualified SPs in MLB; League Avg: .236 — 88th Percentile.

Opponents have a miss rate of 33% (35/107) against Robbie Ray on the first pitch of at-bats this season — 5th best among qualified SPs in MLB; League Avg: 24% — 94th Percentile.

Robbie Ray has allowed a slugging percentage of just .292 (33 Total Bases / 113 ABs) when going through the lineup the second time in a game this season — tied for 7th best among qualified SPs in MLB; League Avg: .390 — 92nd Percentile.

Guardians Keys to the Game vs. the Giants

The Guardians were 71-2 (.973) when leading entering the 7th inning in the 2024 season — best in MLB; League Avg: .856.

The Guardians were 82-0 (1.000) when leading entering the 9th inning in the 2024 season — best in MLB; League Avg: .949.

The Guardians are 99-4 (.961) when leading entering the 7th inning since last season — best in MLB; League Avg: .859.

The Guardians were just 3-61 (.047) when trailing entering the 8th inning in the 2024 season — 2nd lowest in MLB; League Avg: .100.

Giants Keys to the Game vs. the Guardians

The Giants are 7-24 (.226) when trailing entering the 8th inning this season — best in MLB; League Avg: .096.

The Giants are 3-26 (.103) when trailing entering the 9th inning this season — 3rd best in MLB; League Avg: .045.

The Giants are 13-169 (.071) when trailing entering the 9th inning since the 2023 season — tied for 4th best in MLB; League Avg: .049.

The Giants are 8-24 (.250) when trailing entering the 7th inning this season — 2nd best in MLB; League Avg: .135.

Guardians hitters have put just 34% of balls in play to the left side of the field since the 2023 season — lowest in MLB; League Avg: 38%.

The Guardians are batting just .196 in righty-righty matchups this season — lowest in MLB; League Avg: .245.

Guardians hitters are slugging just .306 in righty-righty matchups this season — lowest in MLB; League Avg: .390.

Guardians hitters have a swing rate of 64% with two-strikes since the 2023 season — highest in MLB; League Avg: 60%.

Giants hitters had an OPS of just .683 (1,790 PA’s) against LHP in the 2023 season — 3rd lowest in MLB; League Avg: .742.

The Giants batted just .151 with two-strikes in the 2023 season — 2nd lowest in MLB; League Avg: .172.

The Giants are batting just .282 on the first pitch of at-bats this season — 2nd lowest in MLB; League Avg: .340.

Giants hitters have struck out in 25% of their PA’s against LHP since last season — tied for 5th highest in MLB; League Avg: 23%.

Opponents had a groundball batting average of just .207 against Guardians pitchers with runners on base in the 2024 season — best in MLB; League Avg: .262.

Opponents had a groundball batting average of just .223 against Guardians pitchers in the 2024 season — best in MLB; League Avg: .249.

The Guardians allowed 0.87 runs per game (140/161) in late innings in the 2024 season — best in MLB; League Avg: 1.29.

Opponents had a groundball rate of just 41% against Guardians pitchers in 2023 — 5th lowest in MLB; League Avg: 43%.

Opponents had a groundball rate of 50% against Giants pitchers in 2023 — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 49% against Giants pitchers since the 2023 season — highest in MLB; League Avg: 43%.

Opponents had a groundball rate of 49% against Giants pitchers in the 2024 season — highest in MLB; League Avg: 43%.

Opponents have a groundball rate of 48% against Giants pitchers since last season — highest in MLB; League Avg: 43%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.