Guardians vs Red Sox Prediction, Odds & Player Prop Bets Today – MLB, Apr 17

Boston Red Sox's Masataka Yoshida bats during the first inning of a baseball game against the Minnesota Twins, Tuesday, June 20, 2023, in Minneapolis.
(AP Photo/Abbie Parr)
  • The Red Sox are -130 favorites vs the Guardians
  • Guardians vs Red Sox Over / Under today: 8.5 Runs
  • Guardians / Red Sox TV Channel: BSGL | NESN | MLBN

The Cleveland Guardians (+110) visit Fenway Park to take on the Boston Red Sox (-130) on Wednesday, April 17, 2024. First pitch is scheduled for 7:10pm EDT in Boston, MA.

This season, the Guardians are 12-5 against the spread (ATS), while the Red Sox are 9-9 ATS.

Guardians vs Red Sox Starting Pitchers Today:

  • Guardians starting pitcher: Ben Lively 0-0, 0.00 ERA
  • Red Sox starting pitcher: Tanner Houck 2-1, 2.00 ERA

Guardians vs. Red Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians+1.5 -175O 8.5 -105+110
Red Sox -1.5 +145U 8.5 -115-130

Guardians vs Red Sox Prediction for Today’s Game

Based on recent trends the model predicts the Red Sox will win Wednesday‘s MLB game with 53.6% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Myles Straw has hit the Runs Under in his last 11 away games (+11.00 Units / 40% ROI)
  • Estevan Florial has hit the Singles Over in 10 of his last 16 away games (+9.10 Units / 57% ROI)
  • Kole Calhoun has hit the Singles Under in 18 of his last 24 games (+8.75 Units / 21% ROI)
  • Brayan Rocchio has hit the Total Bases Over in 10 of his last 13 away games (+6.15 Units / 30% ROI)
  • Triston McKenzie has hit the Strikeouts Under in his last 6 games (+6.00 Units / 65% ROI)

And here are some favorite MLB player prop bets for Red Sox players for Wednesday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Best Bets Today:

  • Pablo Reyes has hit the Hits Under in 9 of his last 12 games at home (+10.25 Units / 85% ROI)
  • Pablo Reyes has hit the Hits Runs and RBIs Under in 11 of his last 12 games at home (+9.95 Units / 64% ROI)
  • Kutter Crawford has hit the Earned Runs Under in 15 of his last 20 games (+9.40 Units / 38% ROI)
  • Pablo Reyes has hit the Total Bases Under in 12 of his last 16 games (+8.85 Units / 38% ROI)
  • Kutter Crawford has hit the Strikeouts Over in 10 of his last 12 games (+8.60 Units / 62% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 85 of their last 146 games (+21.85 Units / 14% ROI)
  • The Cleveland Guardians have covered the Run Line in 34 of their last 60 away games (+6.30 Units / 8% ROI)
  • The Cleveland Guardians have covered the 1st Five Innings (F5) Run Line in 25 of their last 44 away games (+5.36 Units / 11% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Moneyline in 22 of their last 44 away games (+5.35 Units / 11% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 34 games (+4.72 Units / 12% ROI)
  • The Boston Red Sox have hit the Game Total Under in 15 of their last 19 games (+10.60 Units / 50% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Under in 10 of their last 15 games (+5.49 Units / 34% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 12-5 against the Run Line (+6.7 Units / 28.15% ROI).

  • 12-5 when betting on the Moneyline for +6.65 Units / 28.73% ROI
  • 10-6 when betting on the total runs Over for +3.3 Units / 17.41% ROI
  • 6-10 when betting on the total runs Under for -5 Units / -27.03% ROI

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 9-9 against the Run Line (-0.75 Units / -3.08% ROI).

  • 9-9 when betting on the Moneyline for -0.8 Units / -3.74% ROI
  • 8-9 when betting on the total runs Over for -1.9 Units / -9.48% ROI
  • 9-8 when betting on the total runs Under for +0.35 Units / 1.79% ROI

Red Sox vs Guardians Home Run Prop Bets Today

Over Under
Triston Casas (BOS) 0.5 +600 0.5 -900
Jarren Duran (BOS) 0.5 +650 0.5 -1000
Enmanuel Valdez (BOS) 0.5 +650 0.5 -1000
Josh Naylor (CLE) 0.5 +700 0.5 -1100
Bo Naylor (CLE) 0.5 +700 0.5 -1100

Red Sox vs Guardians Total Hits Prop Bets Today

Over Under
Triston Casas (BOS) 0.5 -225 0.5 +170
Enmanuel Valdez (BOS) 0.5 -200 0.5 +155
Gabriel Arias (CLE) 0.5 -190 0.5 +145
Ceddanne Rafaela (BOS) 0.5 -185 0.5 +140
Bo Naylor (CLE) 0.5 -185 0.5 +135

Red Sox vs Guardians RBI Prop Bets Today

Over Under
Josh Naylor (CLE) 0.5 +110 0.5 -145
Jose Ramirez (CLE) 0.5 +120 0.5 -155
Jarren Duran (BOS) 0.5 +130 0.5 -175
Triston Casas (BOS) 0.5 +135 0.5 -175
Will Brennan (CLE) 0.5 +155 0.5 -210

Red Sox vs Guardians Strikeout Prop Bets Today

Over Under

Opposing hitters had a miss rate of just 15% (23/152) against Ben Lively when he was behind in the count in the 2023 season — 6th lowest in MLB among starting pitchers with at least 64 total IP; League Avg: 23% — fourth Percentile.

Ben Lively has an ERA of 6.75 (42.2 IP) against division opponents since last season — 4th highest in MLB among starting pitchers with at least 71 total IP; League Avg: 4.29 — third Percentile.

Ben Lively has allowed an average Exit Velocity of just 88.4 MPH against his fastballs since last season (148 balls in play) — 5th best in MLB among starting pitchers with at least 71 total IP; League Avg: 91.0

Ben Lively had an ERA of 6.75 (42.2 IP) against division opponents in the 2023 season — 3rd highest in MLB among starting pitchers with at least 64 total IP; League Avg: 4.27 — third Percentile.

Red Sox Starting Pitcher Stats & Trends

Tanner Houck has thrown his slider 47% of the time (131/280) this season — highest among in AL; League Avg: 24% — 100th Percentile.

Tanner Houck has walked 2 of 76 batters (3%) this season — 4th best among qualified SPs in MLB; League Avg: 8% — 96th Percentile.

Tanner Houck has walked 2 of 76 batters (3%) this season — 3rd best among in AL; League Avg: 7% — 95th Percentile.

Tanner Houck has thrown his slider 42% of the time (84/202) in non-two strike counts this season — 2nd highest among in AL; League Avg: 23% — 97th Percentile.

Guardians Keys to the Game vs. the Red Sox

The Guardians were just 5-15 (.250) when tied entering the 7th inning in 2023 — lowest in MLB; League Avg: .500.

The Guardians are 35-117 (.229) when trailing entering the 7th inning since the 2022 season — best in MLB; League Avg: .132.

The Guardians are 24-124 (.161) when trailing entering the 8th inning since the 2022 season — 2nd best in MLB; League Avg: .094.

The Guardians were just 5-15 (.250) when tied entering the 8th inning in 2023 — 2nd lowest in MLB; League Avg: .500.

Red Sox Keys to the Game vs. the Guardians

The Red Sox are just 18-31 (.367) after a home loss since the 2023 season — 2nd lowest in MLB; League Avg: .509.

The Red Sox are just 1-80 (.012) when trailing entering the 9th inning since the 2023 season — 2nd lowest in MLB; League Avg: .051.

The Red Sox were 64-3 (.955) when leading entering the 8th inning in 2023 — 2nd best in MLB; League Avg: .899.

The Red Sox were just 1-74 (.013) when trailing entering the 9th inning in 2023 — 3rd lowest in MLB; League Avg: .051.

The Guardians are batting .404 when facing the starting pitcher for the 3rd time in a game this season — best in MLB; League Avg: .259.

Guardians hitters slugged just .367 against LHP in the 2023 season — lowest in MLB; League Avg: .419.

Guardians hitters put just 34% of balls in play to the left side of the field in the 2023 season — lowest in MLB; League Avg: 39%.

The Guardians batted just .232 against LHP in the 2023 season — tied for lowest in MLB; League Avg: .254.

The Red Sox batted .182 on pitches out of the zone in the 2023 season — best in MLB; League Avg: .151.

The Red Sox batted .300 when facing the starting pitcher for the 3rd time in a game in the 2023 season — 2nd best in MLB; League Avg: .267.

Red Sox hitters slugged .266 on pitches out of the zone in the 2023 season — best in MLB; League Avg: .211.

The Red Sox are batting .272 at home since the 2022 season — 2nd best in MLB; League Avg: .249.

Opponents have a miss rate of 29% against Guardians pitchers this season — best in MLB; League Avg: 25%.

Guardians pitchers have a strikeout rate of 29% with runners in scoring position this season — best in MLB; League Avg: 21%.

Opponents have a groundball rate of just 41% against Guardians pitchers since last season — 5th lowest in MLB; League Avg: 43%.

Guardians pitchers have an ERA of 2.36 (99.0 IP) on the road this season — 2nd best in MLB; League Avg: 4.08.

Red Sox pitchers have a strikeout rate of 25% this season — 4th best in MLB; League Avg: 23%.

Red Sox pitchers have walked 114 of 1,601 batters (7%) when facing the leadoff batter in the inning since last season — 5th best in MLB; League Avg: 8%.

Red Sox pitchers have an ERA of 1.49 (90.1 IP) on the road this season — best in MLB; League Avg: 4.08.

The Red Sox have allowed 6.50 runs per game (52/8) at home this season — 2nd highest in MLB; League Avg: 4.69.

Red Sox vs. Guardians Injuries Tonight That May Affect Prop Bets 

  • Wyatt Mills (Boston Red Sox): Elbow, 60-Day IL
  • Vaughn Grissom (Boston Red Sox): Hamstring, 10-Day IL
  • Michael Fulmer (Boston Red Sox): Elbow, 60-Day IL
  • Zack Kelly (Boston Red Sox): Oblique, Day-To-Day
  • Bryan Mata (Boston Red Sox): Hamstring, 15-Day IL
  • Chris Murphy (Boston Red Sox): Elbow, 60-Day IL
  • Kenley Jansen (Boston Red Sox): Back, Day-To-Day
  • Brandon Walter (Boston Red Sox): Shoulder, 7-Day IL
  • Lucas Giolito (Boston Red Sox): Elbow, 60-Day IL
  • Rob Refsnyder (Boston Red Sox): Toe, 10-Day IL
  • Yu Chang (Boston Red Sox): Oblique, Out
  • Daniel Espino (Cleveland Guardians): Shoulder, Out
  • Gavin Williams (Cleveland Guardians): Elbow, 15-Day IL
  • Ben Lively (Cleveland Guardians): Illness, 15-Day IL
  • Luis Ortiz (Cleveland Guardians): Ankle, 15-Day IL
  • Xzavion Curry (Cleveland Guardians): Illness, 15-Day IL
  • Joey Cantillo (Cleveland Guardians): Hamstring, Out
  • Angel Martinez (Cleveland Guardians): Foot, 10-Day IL
  • Sam Hentges (Cleveland Guardians): Finger, 15-Day IL
  • Trevor Stephan (Cleveland Guardians): Elbow, 60-Day IL
  • George Valera (Cleveland Guardians): Hamstring, Out
  • James Karinchak (Cleveland Guardians): Shoulder, 60-Day IL

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.