Guardians vs White Sox Prediction, Odds & Player Prop Bets Today – MLB, Sep 11

Chicago White Sox's watches the flight of the ball during a baseball game against the Los Angeles Angels Wednesday, May 31, 2023, in Chicago.
(AP Photo/Charles Rex Arbogast)
  • The Guardians are -225 favorites vs the White Sox
  • Guardians vs White Sox Over / Under today: 8 Runs
  • Guardians / White Sox TV Channel: BSGL | NSCH | MLBN

The Cleveland Guardians (-225) visit Guaranteed Rate Field to take on the Chicago White Sox (+180) on Wednesday, September 11, 2024. First pitch is scheduled for 2:10pm EDT in Chicago, IL.

This season, the Guardians are 83-62 against the spread (ATS), while the White Sox are 58-88 ATS.

Guardians vs White Sox Starting Pitchers Today:

  • Guardians starting pitcher: Matthew Boyd 2-1, 2.20 ERA
  • White Sox starting pitcher: Davis Martin 0-3, 3.32 ERA

Guardians vs. White Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Guardians-2.5 +105O 8 -120-225
White Sox +2.5 -130U 8 +100+180

Guardians vs White Sox Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Wednesday‘s MLB game with 74.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Bets Today:

  • Brayan Rocchio has hit the Home Runs Over in 3 of his last 9 away games (+28.50 Units / 317% ROI)
  • Steven Kwan has hit the Hits Under in 37 of his last 47 games (+22.95 Units / 24% ROI)
  • Steven Kwan has hit the Total Bases Under in 23 of his last 25 away games (+20.80 Units / 55% ROI)
  • Tyler Freeman has hit the Hits Runs and RBIs Under in 13 of his last 15 games (+11.25 Units / 54% ROI)
  • Andres Gimenez has hit the Runs Under in 18 of his last 22 away games (+11.25 Units / 28% ROI)

And here are some favorite MLB player prop bets for White Sox players for Wednesday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Best Bets Today:

  • Andrew Benintendi has hit the Home Runs Over in 7 of his last 30 games (+24.00 Units / 80% ROI)
  • Luis Robert has hit the Total Bases Under in 33 of his last 48 games (+16.10 Units / 25% ROI)
  • Gavin Sheets has hit the Singles Over in 18 of his last 25 games (+15.70 Units / 63% ROI)
  • Luis Robert has hit the Runs Under in 35 of his last 48 games (+14.60 Units / 20% ROI)
  • Luis Robert has hit the Hits Runs and RBIs Under in 29 of his last 44 games (+11.80 Units / 22% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 42 of their last 70 away games (+16.90 Units / 22% ROI)
  • The Cleveland Guardians have hit the Team Total Under in 29 of their last 41 away games (+15.80 Units / 33% ROI)
  • The Cleveland Guardians have hit the Moneyline in 83 of their last 145 games (+11.47 Units / 6% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 11 of their last 16 away games (+7.10 Units / 43% ROI)
  • The Cleveland Guardians have covered the Run Line in 11 of their last 17 games (+5.90 Units / 27% ROI)
  • The Chicago White Sox have hit the Game Total Under in their last 6 games at home (+6.00 Units / 92% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 6 of their last 8 games at home (+4.05 Units / 46% ROI)
  • The Chicago White Sox have hit the Moneyline in 2 of their last 6 games (+1.35 Units / 22% ROI)

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 73-72 against the Run Line (+2.3 Units / 1.26% ROI).

  • 83-62 when betting on the Moneyline for +11.47 Units / 6.15% ROI
  • 66-70 when betting on the total runs Over for -11.5 Units / -7.18% ROI
  • 70-66 when betting on the total runs Under for -2.55 Units / -1.61% ROI

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are 58-88 against the Run Line (-36.35 Units / -21.23% ROI).

  • 33-113 when betting on the Moneyline for -62.3 Units / -42.05% ROI
  • 62-74 when betting on the total runs Over for -19.8 Units / -12.42% ROI
  • 74-62 when betting on the total runs Under for +6.4 Units / 4.06% ROI

White Sox vs Guardians Home Run Prop Bets Today

Over Under
Jose Ramirez (CLE) 0.5 +350 0.5 -450
Josh Naylor (CLE) 0.5 +360 0.5 -500
Kyle Manzardo (CLE) 0.5 +425 0.5 -600
Luis Robert (CWS) 0.5 +425 0.5 -650
Andrew Vaughn (CWS) 0.5 +425 0.5 -600

White Sox vs Guardians Total Hits Prop Bets Today

Over Under
Josh Naylor (CLE) 0.5 -275 0.5 +195
Andrew Vaughn (CWS) 0.5 -275 0.5 +200
Jose Ramirez (CLE) 0.5 -250 0.5 +195
Luis Robert (CWS) 0.5 -225 0.5 +160
Lane Thomas (CLE) 0.5 -210 0.5 +160

White Sox vs Guardians RBI Prop Bets Today

Over Under
Jose Ramirez (CLE) 0.5 +115 0.5 -155
Josh Naylor (CLE) 0.5 +120 0.5 -155
Andrew Vaughn (CWS) 0.5 +145 0.5 -190
Lane Thomas (CLE) 0.5 +160 0.5 -210
Kyle Manzardo (CLE) 0.5 +175 0.5 -250

White Sox vs Guardians Strikeout Prop Bets Today

Over Under
Matthew Boyd (CLE) 5.5 -140 5.5 +105
Davis Martin (CWS) 4.5 +155 4.5 -200

Matthew Boyd has allowed an OPS of just .278 (18 PA’s) when going through the lineup the second time in a game in his last two starts — 6th best in MLB over the last two weeks; League Avg: .669 — 94th Percentile.

Matthew Boyd’s has 14 strikeouts and no walks in his last two starts — tied for best in MLB K:BB ratio over the last two weeks; League Avg: 3.6 — 100th Percentile.

Matthew Boyd has not walked any of the 43 batters that he has faced in his last two starts — tied for best in MLB over the last two weeks; League Avg: 7% — 100th Percentile.

Matthew Boyd has allowed an OBP of just .107 (28 PA’s) with two-strikes in his last two starts — tied for 5th best in MLB over the last two weeks; League Avg: .223 — 94th Percentile.

White Sox Starting Pitcher Stats & Trends

Opposing hitters have no hits in their last 26 ABs ending on a two-strike breaking pitch from Davis Martin. — Josh Hader has the longest active streak at 37.

Davis Martin has allowed no extra-base hits in his last 10.1 innings pitched — Brusdar Graterol has the longest active streak at 29.2.

Davis Martin had a strike rate of just 59% (51/86) in his last start — 7th lowest in MLB over the last week; League Avg: 65% — seventh Percentile.

Davis Martin has a strike rate of just 59% (51/86) over the past seven days (1 games) — 2nd lowest among AL Starters over the last week; League Avg: 65% — fourth Percentile.

Guardians Keys to the Game vs. the White Sox

The Guardians are 84-25 (.771) when they’ve hit 2 or more home runs since the 2022 season — 4th best in MLB; League Avg: .700.

The Guardians are 70-2 (.972) when leading entering the 8th inning this season — best in MLB; League Avg: .899.

The Guardians are just 2-54 (.036) when trailing entering the 8th inning this season — 2nd lowest in MLB; League Avg: .101.

The Guardians are 48-34 (.585) after a win this season — 2nd best in MLB; League Avg: .492.

White Sox Keys to the Game vs. the Guardians

The White Sox are just 1-14 (.067) after a road win this season — lowest in MLB; League Avg: .467.

The White Sox are just 77-71 (.520) when allowing 4 or fewer runs since the 2023 season — lowest in MLB; League Avg: .729.

The White Sox are just 9-46 (.164) after a home loss this season — lowest in MLB; League Avg: .530.

The White Sox are just 29-38 (.433) when allowing 4 or fewer runs this season — lowest in MLB; League Avg: .725.

Guardians hitters have put just 34% of balls in play to the left side of the field since last season — lowest in MLB; League Avg: 38%.

The Guardians are batting just .286 on the first pitch of at-bats this season — 2nd lowest in MLB; League Avg: .332.

Guardians hitters have just 2,326 strikeouts in 12,583 PA’s (18%) against RHP since the 2022 season — best in MLB; League Avg: 23%.

Guardians hitters are slugging .688 against LHP this month (7 games) — best in MLB; League Avg: .349.

White Sox hitters have an OBP of just .284 (8,617 PA’s) against RHP since last season — lowest in MLB; League Avg: .316.

The White Sox have a winning percentage of just 23% this season — lowest in MLB; League Avg: 50%.

The White Sox have a winning percentage of just 24% at home this season — lowest in MLB; League Avg: 52%.

White Sox hitters have an OPS of just .648 (8,617 PA’s) against RHP since last season — lowest in MLB; League Avg: .723.

Opponents have a groundball batting average of just .201 against Guardians pitchers with runners on base this season — best in MLB; League Avg: .262.

Opponents have a groundball batting average of just .221 against Guardians pitchers this season — best in MLB; League Avg: .250.

Guardians pitchers have won 48% of games in which they have allowed their opponent to score in three different innings at home this season — highest in MLB; League Avg: 27%.

Opponents have a groundball batting average of just .226 against Guardians pitchers with runners on base since last season — best in MLB; League Avg: .260.

The White Sox have won just 10% of games in which their opponents scored first this season — lowest in MLB; League Avg: 31%.

In games when their opponents have scored three or more runs in an inning, the White Sox have won just just 1% of the time this season — lowest in MLB; League Avg: 24%.

White Sox pitchers have walked 577 of 5,640 batters (10%) this season — highest in MLB; League Avg: 8%.

The White Sox have won just 12% of home games in which their opponents scored first this season — lowest in MLB; League Avg: 35%.

White Sox vs. Guardians Injuries Tonight That May Affect Prop Bets 

  • Chicago White Sox – No Injuries Reported
  • Cleveland Guardians – No Injuries Reported

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.