Kansas City Royals vs San Diego Padres Prediction, Odds & Player Prop Bets Today – MLB, Jun 21

  • The San Diego Padres are -170 favorites vs the Kansas City Royals
  • Kansas City Royals vs San Diego Padres Over / Under today: 7.5 Runs
  • Kansas City Royals / San Diego Padres TV Channel: FOX

The Kansas City Royals (+140) visit Petco Park to take on the San Diego Padres (-170) on Saturday, June 21, 2025. First pitch is scheduled for 7:15pm EDT in San Diego, CA, CA.

This season, the Kansas City Royals are 38-38 against the spread (ATS), while the San Diego Padres are 41-34 ATS.

Kansas City Royals vs San Diego Padres Starting Pitchers Today:

  • Kansas City Royals starting pitcher: , ERA
  • San Diego Padres starting pitcher: , ERA

Kansas City Royals vs. San Diego Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Kansas City Royals+1.5 -165O 7.5 -118+140
San Diego Padres -1.5 +135U 7.5 -102-170

Kansas City Royals vs San Diego Padres Prediction for Today’s Game

Based on recent trends the model predicts the will win Saturday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Kansas City Royals players for Saturday‘s game, looking at profitable historical betting trends:

Best Kansas City Royals Player Prop Bets Today:

  • Maikel Garcia has hit the Home Runs Over in 3 of his last 8 away games (+20.00 Units / 250% ROI)
  • Vinnie Pasquantino has hit the Total Bases Over in 17 of his last 25 away games (+10.90 Units / 37% ROI)
  • Maikel Garcia has hit the Hits Over in 17 of his last 25 away games (+10.00 Units / 23% ROI)
  • Maikel Garcia has hit the Hits Runs and RBIs Over in 18 of his last 25 away games (+9.55 Units / 31% ROI)
  • Vinnie Pasquantino has hit the Singles Over in 15 of his last 20 away games (+9.40 Units / 41% ROI)

And here are some favorite MLB player prop bets for San Diego Padres players for Saturday‘s game, looking at profitable historical betting trends:

Best San Diego Padres Player Prop Best Bets Today:

  • Fernando Tatis Jr. has hit the RBIs Under in 22 of his last 25 games (+15.00 Units / 26% ROI)
  • Dylan Cease has hit the Earned Runs Over in 19 of his last 25 games (+13.45 Units / 44% ROI)
  • Luis Arraez has hit the Singles Over in 21 of his last 25 games at home (+13.25 Units / 27% ROI)
  • Fernando Tatis Jr. has hit the Total Bases Under in 19 of his last 25 games (+11.50 Units / 36% ROI)
  • Gavin Sheets has hit the Runs Under in 17 of his last 20 games (+10.80 Units / 25% ROI)
  • The Kansas City Royals have hit the Team Total Under in 52 of their last 76 games (+26.90 Units / 31% ROI)
  • The Kansas City Royals have covered the Run Line in 22 of their last 26 away games (+17.95 Units / 45% ROI)
  • The Kansas City Royals have hit the 1st Five Innings (F5) Moneyline in 16 of their last 25 away games (+13.80 Units / 49% ROI)
  • The Kansas City Royals have covered the 1st Five Innings (F5) Run Line in 20 of their last 26 away games (+13.40 Units / 42% ROI)
  • The Kansas City Royals have hit the Game Total Under in 41 of their last 68 games (+12.40 Units / 16% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 22 of their last 33 games (+10.35 Units / 26% ROI)
  • The San Diego Padres have hit the Team Total Over in 22 of their last 34 games at home (+8.90 Units / 22% ROI)
  • The San Diego Padres have covered the Run Line in 19 of their last 32 games at home (+8.45 Units / 23% ROI)
  • The San Diego Padres have hit the Game Total Under in 35 of their last 61 games (+7.40 Units / 11% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 20 of their last 32 games at home (+6.45 Units / 17% ROI)

Kansas City Royals Against the Spread (ATS) Record

Against the spread this season, the Kansas City Royals are 40-36 against the Run Line (-4.8 Units / -4.44% ROI).

  • 38-38 when betting on the Moneyline for -1.1 Units / -1.18% ROI
  • 31-44 when betting on the total runs Over for -16.77 Units / -20.21% ROI
  • 44-31 when betting on the total runs Under for +9.9 Units / 11.75% ROI

San Diego Padres Against the Spread (ATS) Record

Against the spread this season, the San Diego Padres are 41-34 against the Run Line (+2.3 Units / 2.32% ROI).

  • 40-35 when betting on the Moneyline for +0.05 Units / 0.05% ROI
  • 32-41 when betting on the total runs Over for -12.7 Units / -15.48% ROI
  • 41-32 when betting on the total runs Under for +5.55 Units / 6.67% ROI

San Diego Padres vs Kansas City Royals Home Run Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +300 0.5 -400
Fernando Tatis Jr. (SD) 0.5 +400 0.5 -525
Bobby Witt Jr. (KC) 0.5 +425 0.5 -600
Vinnie Pasquantino (KC) 0.5 +500 0.5 -700
Salvador Perez (KC) 0.5 +550 0.5 -800

San Diego Padres vs Kansas City Royals Total Hits Prop Bets Today

Over Under
Manny Machado (SD) 0.5 -275 0.5 +200
Fernando Tatis Jr. (SD) 0.5 -250 0.5 +185
Bobby Witt Jr. (KC) 0.5 -220 0.5 +165
Xander Bogaerts (SD) 0.5 -210 0.5 +155
Maikel Garcia (KC) 0.5 -190 0.5 +140

San Diego Padres vs Kansas City Royals RBI Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +130 0.5 -175
Vinnie Pasquantino (KC) 0.5 +155 0.5 -210
Fernando Tatis Jr. (SD) 0.5 +185 0.5 -250
Bobby Witt Jr. (KC) 0.5 +190 0.5 -250
Gavin Sheets (SD) 0.5 +200 0.5 -275

San Diego Padres vs Kansas City Royals Strikeout Prop Bets Today

Over Under
Noah Cameron (KC) 3.5 -155 3.5 +115
Dylan Cease (SD) 6.5 -110 6.5 -115

starting pitcher – away

San Diego Padres Starting Pitcher Stats & Trends

starting pitcher – home

Kansas City Royals Keys to the Game vs. the San Diego Padres

keys to the game – away

San Diego Padres Keys to the Game vs. the Kansas City Royals

keys to the game – home

team hitters – away

team hitters – home

team pitchers – away

team pitchers – home

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.