Marlins vs Padres Prediction, Odds & Player Prop Bets Today – MLB, May 28

MLB betting odds, predictions and betting odds for today's games
(AP Photo)
  • The Padres are -170 favorites vs the Marlins
  • Marlins vs Padres Over / Under today: 8.5 Runs
  • Marlins / Padres TV Channel: FDFL | PDTV

The Miami Marlins (+140) visit Petco Park to take on the San Diego Padres (-170) on Wednesday, May 28, 2025. First pitch is scheduled for 4:10pm EDT in San Diego, CA.

This season, the Marlins are 21-32 against the spread (ATS), while the Padres are 29-24 ATS.

Marlins vs Padres Starting Pitchers Today:

  • Marlins starting pitcher: Sandy Alcantara 2-7, 8.05 ERA
  • Padres starting pitcher: Kyle Hart 2-2, 6.10 ERA

Marlins vs. Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Marlins+1.5 -155O 8.5 -115+140
Padres -1.5 +125U 8.5 -105-170

Marlins vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Wednesday‘s MLB game with 59.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Marlins players for Wednesday‘s game, looking at profitable historical betting trends:

Best Marlins Player Prop Bets Today:

  • Kyle Stowers has hit the Home Runs Over in 3 of his last 10 away games (+13.60 Units / 136% ROI)
  • Otto Lopez has hit the Total Bases Under in 15 of his last 20 games (+10.85 Units / 35% ROI)
  • Connor Norby has hit the Hits Over in 13 of his last 15 games (+9.55 Units / 36% ROI)
  • Sandy Alcantara has hit the Pitching Outs Under in 9 of his last 10 games (+9.25 Units / 89% ROI)
  • Sandy Alcantara has hit the Earned Runs Over in his last 8 games (+8.70 Units / 88% ROI)

And here are some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

  • Gavin Sheets has hit the Home Runs Over in 4 of his last 10 games (+22.70 Units / 227% ROI)
  • Manny Machado has hit the Hits Runs and RBIs Over in 20 of his last 25 games (+14.00 Units / 45% ROI)
  • Luis Arraez has hit the Singles Over in 14 of his last 15 games at home (+11.95 Units / 41% ROI)
  • Manny Machado has hit the Runs Over in 17 of his last 25 games (+10.75 Units / 39% ROI)
  • Luis Arraez has hit the Total Bases Under in 19 of his last 25 games at home (+9.60 Units / 23% ROI)
  • The Miami Marlins have hit the Game Total Over in 25 of their last 41 games (+7.15 Units / 16% ROI)
  • The Miami Marlins have hit the Team Total Over in 30 of their last 49 games (+7.05 Units / 12% ROI)
  • The Miami Marlins have covered the 1st Five Innings (F5) Run Line in 10 of their last 13 games (+6.45 Units / 39% ROI)
  • The Miami Marlins have hit the 1st Five Innings (F5) Moneyline in 7 of their last 12 games (+5.50 Units / 45% ROI)
  • The Miami Marlins have covered the Run Line in 20 of their last 34 games (+5.20 Units / 12% ROI)
  • The San Diego Padres have covered the Run Line in 16 of their last 24 games at home (+10.40 Units / 38% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 16 of their last 24 games at home (+7.05 Units / 25% ROI)
  • The San Diego Padres have hit the Team Total Over in 17 of their last 26 games at home (+7.00 Units / 23% ROI)
  • The San Diego Padres have hit the Game Total Under in 16 of their last 24 games at home (+6.95 Units / 26% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 9 of their last 11 games (+6.90 Units / 53% ROI)

Marlins Against the Spread (ATS) Record

Against the spread this season, the Marlins are 28-25 against the Run Line (+0.5 Units / 0.76% ROI).

  • 21-32 when betting on the Moneyline for -2.85 Units / -5.15% ROI
  • 31-22 when betting on the total runs Over for +6.25 Units / 10.58% ROI
  • 22-31 when betting on the total runs Under for -11.9 Units / -20.68% ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 29-24 against the Run Line (+1.55 Units / 2.22% ROI).

  • 31-22 when betting on the Moneyline for +3.8 Units / 5.17% ROI
  • 22-29 when betting on the total runs Over for -9.45 Units / -16.43% ROI
  • 29-22 when betting on the total runs Under for +4.25 Units / 7.17% ROI

Padres vs Marlins Home Run Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +425 0.5 -600
Connor Norby (MIA) 0.5 +475 0.5 -700
Manny Machado (SD) 0.5 +475 0.5 -650
Agustin Ramirez (MIA) 0.5 +525 0.5 -750
Eric Wagaman (MIA) 0.5 +550 0.5 -800

Padres vs Marlins Total Hits Prop Bets Today

Over Under
Eric Wagaman (MIA) 0.5 -235 0.5 +180
Jose Iglesias (SD) 0.5 -235 0.5 +175
Agustin Ramirez (MIA) 0.5 -225 0.5 +170
Xander Bogaerts (SD) 0.5 -220 0.5 +160
Connor Norby (MIA) 0.5 -200 0.5 +150

Padres vs Marlins RBI Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +135 0.5 -175
Jackson Merrill (SD) 0.5 +140 0.5 -185
Connor Norby (MIA) 0.5 +160 0.5 -210
Xander Bogaerts (SD) 0.5 +170 0.5 -220
Gavin Sheets (SD) 0.5 +170 0.5 -225

Padres vs Marlins Strikeout Prop Bets Today

Over Under
Kyle Hart (SD) 3.5 -160 3.5 +125
Sandy Alcantara (MIA) 4.5 +115 4.5 -150

Sandy Alcantara has had second base stolen on him 16 times this season — most in MLB — 100th Percentile.

Sandy Alcantara has allowed an OBP of .429 (212 PA’s) with runners in scoring position since the 2023 season — highest in MLB among starting pitchers with at least 150 total IP; League Avg: .319 — 0 Percentile.

Sandy Alcantara has an ERA of 8.04 (47.0 IP)this season — tied for 2nd highest in MLB among starting pitchers with at least 21 total IP; League Avg: 3.83 — first Percentile.

Sandy Alcantara has allowed three-ball counts to 35% of batters he faced (39/110 PA’s) vs left-handed batters this season — highest in MLB among starting pitchers with at least 21 total IP; League Avg: 21% — first Percentile.

Padres Starting Pitcher Stats & Trends

No Matchup notes for this Game

Marlins Keys to the Game vs. the Padres

The Marlins were just 30-51 (.370) at home in the 2024 season — 2nd lowest in MLB; League Avg: .521.

The Marlins were just 39-14 (.736) when leading entering the 7th inning in the 2024 season — 3rd lowest in MLB; League Avg: .856.

The Marlins were just 20-41 (.328) after a win in the 2024 season — tied for lowest in MLB; League Avg: .496.

The Marlins are just 58-14 (.806) when leading entering the 8th inning since last season — 2nd lowest in MLB; League Avg: .901.

Padres Keys to the Game vs. the Marlins

The Padres were 55-38 (.591) after a win in the 2024 season — best in MLB; League Avg: .496.

The Padres are just 0-19 (.000) when trailing entering the 9th inning this season — tied for lowest in MLB; League Avg: .042.

The Padres were 48-33 (.593) on the road in the 2024 season — 2nd best in MLB; League Avg: .478.

The Padres are 85-10 (.895) when scoring 5 or more runs since last season — 2nd best in MLB; League Avg: .806.

Marlins hitters pulled just 42% of balls they’ve put into play in 2023 — lowest in MLB; League Avg: 47%.

The Marlins batted .281 against LHP in the 2023 season — 2nd best in MLB; League Avg: .254.

Marlins hitters pulled just 42% of balls they’ve put into play against RHP in 2023 — lowest in MLB; League Avg: 47%.

Marlins hitters averaged just 3.76 pitches per plate appearance against RHP in the 2024 season — 2nd lowest in MLB; League Avg: 3.89.

Padres hitters have struck out in just 18% of it’s PA’s against LHP since last season — best in MLB; League Avg: 23%.

The Padres batted .275 on the road in the 2024 season — best in MLB; League Avg: .242.

Padres hitters struck out just 799 times in 4,486 PA’s (18%) against RHP in the 2024 season — best in MLB; League Avg: 23%.

Padres hitters struck out just 278 times in 1,617 PA’s (17%) against LHP in the 2024 season — best in MLB; League Avg: 23%.

The Marlins allowed 6.04 runs per game (489/81) at home in the 2024 season — highest in MLB; League Avg: 4.41.

Marlins pitchers had an ERA of 5.37 (751.0 IP) at home in the 2024 season — 2nd highest in MLB; League Avg: 3.98.

Marlins pitchers have allowed a run 36% of the time after an opposing score since last season — 2nd highest in MLB; League Avg: 30%.

The longest HR allowed by the Marlins pitchers in the 2024 season traveled 518.2 feet — — 2nd longest in MLB; League Avg: 470.4

Opponents had a groundball rate of 45% against Padres pitchers in 2023 — 3rd highest in MLB; League Avg: 43%.

Padres pitchers had a strikeout rate of 44% with two-strikes in the 2024 season — tied for 4th best in MLB; League Avg: 42%.

Batters facing the Padres pitchers have struck out in the zone 52% of the time since last season — tied for 4th highest in MLB; League Avg: 50%. since last season — tied for 4th highest in MLB; League Avg: 50%.

Opponents have a miss rate of 27% against Padres pitchers since last season — 4th best in MLB; League Avg: 25%.

More MLB Reading:


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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.