Nationals vs Cubs Prediction, Odds & Player Prop Bets Today – MLB, Sep 22

Chicago Cubs' Dansby Swanson waves to the crowd before batting against his former team the Atlanta Braves in the second inning of a baseball game, Tuesday, Sept. 26, 2023, in Atlanta.
(AP Photo/John Bazemore)
  • The Cubs are -190 favorites vs the Nationals
  • Nationals vs Cubs Over / Under today: 7.5 Runs
  • Nationals / Cubs TV Channel: MAS2 | MARQ

The Washington Nationals (+165) visit Wrigley Field to take on the Chicago Cubs (-200) on Sunday, September 22, 2024. First pitch is scheduled for 2:20pm EDT in Chicago, IL.

This season, the Nationals are against the spread (ATS), while the Cubs are ATS.

Nationals vs Cubs Starting Pitchers Today:

  • Nationals starting pitcher: Jake Irvin 10-12, 4.08 ERA
  • Cubs starting pitcher: Shota Imanaga 14-3, 3.06 ERA

Nationals vs. Cubs Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Nationals+1.5 -130O 7.5 +100+165
Cubs -1.5 +110U 7.5 -120-200

Nationals vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Cubs will win Sunday‘s MLB game with 65.0% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Nationals vs Cubs and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Nationals players for Sunday‘s game, looking at profitable historical betting trends:

Best Nationals Player Prop Bets Today:

  • James Wood has hit the Total Bases Over in 32 of his last 50 games (+11.85 Units / 16% ROI)
  • Luis Garcia has hit the Hits Runs and RBIs Under in 14 of his last 18 games (+11.00 Units / 56% ROI)
  • Dylan Crews has hit the Runs Under in 16 of his last 20 games (+9.95 Units / 31% ROI)
  • Luis Garcia has hit the Hits Under in 12 of his last 18 games (+9.05 Units / 32% ROI)
  • Jake Irvin has hit the Walks Allowed Under in 20 of his last 31 games (+8.95 Units / 25% ROI)

And here are some favorite MLB player prop bets for Cubs players for Sunday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

  • Dansby Swanson has hit the Home Runs Over in 7 of his last 30 games (+20.50 Units / 68% ROI)
  • Dansby Swanson has hit the Runs Over in 21 of his last 30 games (+17.65 Units / 54% ROI)
  • Dansby Swanson has hit the Hits Runs and RBIs Over in 29 of his last 45 games (+13.60 Units / 26% ROI)
  • Ian Happ has hit the Hits Over in 29 of his last 39 games (+13.05 Units / 19% ROI)
  • Ian Happ has hit the Singles Over in 23 of his last 38 games (+12.45 Units / 32% ROI)
  • The Washington Nationals have covered the 1st Five Innings (F5) Run Line in their last 49 games (+53.90 Units / 110% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Moneyline in their last 49 games (+49.00 Units / 75% ROI)
  • The Washington Nationals have covered the Run Line in 82 of their last 146 games (+8.45 Units / 4% ROI)
  • The Washington Nationals have hit the 1st Five Innings (F5) Team Total Over in 32 of their last 54 away games (+8.05 Units / 12% ROI)
  • The Washington Nationals have hit the Game Total Under in 19 of their last 32 games (+6.90 Units / 19% ROI)
  • The Chicago Cubs have hit the Team Total Under in 39 of their last 60 games at home (+16.05 Units / 23% ROI)
  • The Chicago Cubs have hit the Moneyline in 40 of their last 67 games (+11.32 Units / 13% ROI)
  • The Chicago Cubs have hit the Game Total Over in 30 of their last 49 games (+11.20 Units / 21% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 27 of their last 43 games (+8.01 Units / 15% ROI)
  • The Chicago Cubs have covered the 1st Five Innings (F5) Run Line in 16 of their last 23 games at home (+7.55 Units / 26% ROI)

Nationals Against the Spread (ATS) Record

Against the spread this season, the Nationals are against the Run Line ( Units / ROI).

  • away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • away total over record when betting on the total runs Over for over units Units / over ROI ROI
  • away total under record when betting on the total runs Under for under units Units / under ROI ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are against the Run Line ( Units / ROI).

  • home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • home total over record when betting on the total runs Over for over units Units / over ROI ROI
  • home total under record when betting on the total runs Under for under units Units / under ROI ROI

Cubs vs Nationals Home Run Prop Bets Today

Over Under
Seiya Suzuki (CHC) 0.5 +375 0.5 -550
Patrick Wisdom (CHC) 0.5 +375 0.5 -500
Michael Busch (CHC) 0.5 +375 0.5 -550
Ian Happ (CHC) 0.5 +375 0.5 -550
Juan Yepez (WAS) 0.5 +400 0.5 -550

Cubs vs Nationals Total Hits Prop Bets Today

Over Under
Seiya Suzuki (CHC) 0.5 -250 0.5 +175
Nico Hoerner (CHC) 0.5 -250 0.5 +185
Dansby Swanson (CHC) 0.5 -250 0.5 +180
Dylan Crews (WAS) 0.5 -225 0.5 +160
Ian Happ (CHC) 0.5 -225 0.5 +170

Cubs vs Nationals RBI Prop Bets Today

Over Under
Seiya Suzuki (CHC) 0.5 +135 0.5 -185
Cody Bellinger (CHC) 0.5 +155 0.5 -210
Michael Busch (CHC) 0.5 +160 0.5 -210
Ian Happ (CHC) 0.5 +160 0.5 -225
Andrรฉs Chaparro (WAS) 0.5 +160 0.5 -210

Cubs vs Nationals Strikeout Prop Bets Today

Over Under
Jake Irvin (WAS) 4.5 -125 4.5 -105
Shota Imanaga (CHC) 5.5 -105 5.5 -125

Jake Irvin has thrown elevated pitches 48% of the time (439/917) with two-strikes this season — highest among among NL Starters; League Avg: 30% — 100th Percentile.

Jake Irvin has thrown his curveball 27% of the time (297/1,088) when he’s behind in the count since last season — 4th highest in MLB among starting pitchers with at least 126 total CB; League Avg: 10% — 96th Percentile.

Opponents have a two strike miss rate of just 21% (123/574) against Jake Irvin this season — 8th lowest among qualified SPs in MLB; League Avg: 25% — 14th Percentile.

Jake Irvin has thrown his curveball 32% of the time (628/1,980) in non-two strike counts this season — 2nd highest among qualified SPs in MLB; League Avg: 15% — 97th Percentile.

Cubs Starting Pitcher Stats & Trends

Shota Imanaga has walked 28 of 668 batters (4%) this season — 4th best among qualified SPs in MLB; League Avg: 7% — 94th Percentile.

Opponents have a miss rate of 40% (38/96) against Shota Imanaga over the last 14 days — 2nd best among NL Starters over the last two weeks; League Avg: 26% — 97th Percentile.

Opponents are hitting just .203 (48-for-237) against Shota Imanaga when going through the lineup the second time in a game this season — 8th best among qualified SPs in MLB; League Avg: .232 — 86th Percentile.

Opponents have a miss rate of 38% (58/151) against Shota Imanaga this month (3 games) — best among qualified SPs in MLB; League Avg: 26% — 100th Percentile.

Nationals Keys to the Game vs. the Cubs

The Nationals are 11-2 (.846) after a loss as favorites since the 2023 season — 2nd best in MLB; League Avg: .582.

The Nationals are just 59-234 (.201) when scoring 4 or fewer runs since the 2022 season — lowest in MLB; League Avg: .280.

The Nationals are just 73-120 (.378) after a win since the 2022 season — lowest in MLB; League Avg: .508.

The Nationals are 14-6 (.700) after a loss as favorites since the 2022 season — best in MLB; League Avg: .589.

Cubs Keys to the Game vs. the Nationals

The Cubs are just 62-12 (.838) when leading entering the 8th inning this season — 5th lowest in MLB; League Avg: .901.

The Cubs are 23-13 (.639) after a home loss this season — 4th best in MLB; League Avg: .532.

The Cubs are 15-28 (.349) when allowing 10 or more hits this season — 2nd best in MLB; League Avg: .250.

The Cubs are just 55-49 (.529) after a loss as favorites since the 2022 season — 4th lowest in MLB; League Avg: .589.

Nationals hitters had a Hard-Hit Rate of just 36% against RHP in the 2023 season — 2nd lowest in MLB; League Avg: 40%.

The Nationals are batting just .239 when facing the starting pitcher for the 3rd time in a game since last season — tied for 2nd lowest in MLB; League Avg: .264.

Nationals hitters have an OBP of just .296 (1,602 PA’s) when facing the starting pitcher for the 3rd time in a game since last season — lowest in MLB; League Avg: .327.

Nationals hitters have an OPS of just .946 (2,181 PA’s) with the pitcher behind in the count since last season — lowest in MLB; League Avg: 1.088.

The Cubs are batting .283 in lefty-lefty matchups since last season — best in MLB; League Avg: .239.

The Cubs are batting .263 against LHP since last season — 5th best in MLB; League Avg: .250.

Cubs hitters have an OBP of .331 (3,097 PA’s) on the road this season — tied for 4th best in MLB; League Avg: .309.

The Cubs are batting just .228 at home this season — 3rd lowest in MLB; League Avg: .245.

Nationals pitchers have a strikeout rate of just 39% with two-strikes since the 2022 season — 2nd lowest in MLB; League Avg: 42%.

Opponents have a miss rate of just 23% against Nationals pitchers since the 2022 season — 3rd lowest in MLB; League Avg: 26%.

Opponents have a miss rate of just 24% against Nationals pitchers since last season — 3rd lowest in MLB; League Avg: 26%.

Nationals pitchers have a strikeout rate of just 41% with two-strikes this season — 4th lowest in MLB; League Avg: 42%.

Cubs pitchers have induced opposing hitters to ground into just 75 double plays in 1,083 opportunities (7%) this season — lowest in MLB; League Avg: 10%.

Cubs pitchers have an ERA of 3.21 (696.0 IP) at home this season — 2nd best in MLB; League Avg: 3.98.

Cubs pitchers have walked 122 of 1,375 batters (9%) when facing the leadoff batter in the inning this season — 3rd highest in MLB; League Avg: 7%.

Cubs pitchers have a strikeout rate of just 20% this month (19 games) — 2nd lowest in MLB; League Avg: 24%.

Cubs vs. Nationals Injuries Tonight That May Affect Prop Bets 

  • Chicago Cubs – No Injuries Reported
  • Washington Nationals – No Injuries Reported

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.