Orioles vs Red Sox Prediction, Odds & Player Prop Bets Today – MLB, May 25

Boston Red Sox's Jarren Duran plays against the Toronto Blue Jays during the first inning of a baseball game, Saturday, Aug. 5, 2023, in Boston.
(AP Photo/Michael Dwyer)
  • The Orioles are +105 favorites vs the Red Sox
  • Orioles vs Red Sox Over / Under today: 9.5 Runs
  • Orioles / Red Sox TV Channel: MASN | NESN | MLBN

The Baltimore Orioles (+105) visit Fenway Park to take on the Boston Red Sox (-125) on Sunday, May 25, 2025. First pitch is scheduled for 1:35pm EDT in Boston, MA.

This season, the Orioles are 17-34 against the spread (ATS), while the Red Sox are 27-26 ATS.

Orioles vs Red Sox Starting Pitchers Today:

  • Orioles starting pitcher: Dean Kremer 3-5, 5.57 ERA
  • Red Sox starting pitcher: Walker Buehler 4-1, 4.00 ERA

Orioles vs. Red Sox Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Orioles-1.5 +160O 9.5 -115+105
Red Sox +1.5 -210U 9.5 -105-125

Orioles vs Red Sox Prediction for Today’s Game

Based on recent trends the model predicts the Red Sox will win Sunday‘s MLB game with 52.9% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on Orioles vs Red Sox and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for Orioles players for Sunday‘s game, looking at profitable historical betting trends:

Best Orioles Player Prop Bets Today:

  • Gunnar Henderson has hit the Hits Runs and RBIs Under in 19 of his last 25 away games (+12.55 Units / 42% ROI)
  • Jackson Holliday has hit the Singles Over in 19 of his last 25 games (+12.40 Units / 41% ROI)
  • Cedric Mullins has hit the Home Runs Over in 3 of his last 10 games (+11.30 Units / 113% ROI)
  • Jackson Holliday has hit the Hits Over in 18 of his last 25 games (+10.65 Units / 25% ROI)
  • Dylan Carlson has hit the Runs Under in his last 10 games (+10.00 Units / 44% ROI)

And here are some favorite MLB player prop bets for Red Sox players for Sunday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Best Bets Today:

  • Rob Refsnyder has hit the Home Runs Over in 4 of his last 8 games (+22.70 Units / 284% ROI)
  • Wilyer Abreu has hit the Hits Under in 12 of his last 20 games at home (+11.05 Units / 55% ROI)
  • Carlos Narvaez has hit the Total Bases Over in 13 of his last 15 games (+10.70 Units / 53% ROI)
  • Wilyer Abreu has hit the Hits Runs and RBIs Under in 15 of his last 20 games at home (+10.30 Units / 47% ROI)
  • Rafael Devers has hit the Walks Over in 14 of his last 20 games at home (+9.35 Units / 41% ROI)
  • The Baltimore Orioles have hit the Team Total Under in 31 of their last 46 games (+14.35 Units / 27% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Team Total Under in 15 of their last 20 away games (+9.64 Units / 38% ROI)
  • The Baltimore Orioles have hit the Game Total Under in 15 of their last 22 away games (+8.18 Units / 33% ROI)
  • The Baltimore Orioles have covered the 1st Five Innings (F5) Run Line in 6 of their last 10 away games (+1.88 Units / 17% ROI)
  • The Baltimore Orioles have hit the 1st Five Innings (F5) Moneyline in 5 of their last 10 away games (+1.80 Units / 15% ROI)
  • The Boston Red Sox have hit the Team Total Under in 27 of their last 44 games (+7.65 Units / 15% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 24 of their last 49 games (+7.50 Units / 11% ROI)
  • The Boston Red Sox have covered the 1st Five Innings (F5) Run Line in 22 of their last 36 games (+7.45 Units / 17% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Under in 17 of their last 27 games at home (+5.86 Units / 18% ROI)
  • The Boston Red Sox have covered the Run Line in 10 of their last 17 games (+5.15 Units / 24% ROI)

Orioles Against the Spread (ATS) Record

Against the spread this season, the Orioles are 16-34 against the Run Line (-21.66 Units / -33.17% ROI).

  • 17-34 when betting on the Moneyline for -24.45 Units / -39.32% ROI
  • 25-23 when betting on the total runs Over for +0.07 Units / 0.13% ROI
  • 23-25 when betting on the total runs Under for -4.67 Units / -8.24% ROI

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 27-26 against the Run Line (+2.5 Units / 3.7% ROI).

  • 27-27 when betting on the Moneyline for -8.21 Units / -11.08% ROI
  • 26-27 when betting on the total runs Over for -3.47 Units / -5.83% ROI
  • 27-26 when betting on the total runs Under for -1.25 Units / -2.11% ROI

Red Sox vs Orioles Home Run Prop Bets Today

Over Under
Wilyer Abreu (BOS) 0.5 +280 0.5 -350
Rafael Devers (BOS) 0.5 +340 0.5 -450
Jarren Duran (BOS) 0.5 +450 0.5 -625
Gunnar Henderson (BAL) 0.5 +450 0.5 -650
Ryan Mountcastle (BAL) 0.5 +575 0.5 -800

Red Sox vs Orioles Total Hits Prop Bets Today

Over Under
Wilyer Abreu (BOS) 0.5 -250 0.5 +195
Adley Rutschman (BAL) 0.5 -250 0.5 +190
Rafael Devers (BOS) 0.5 -225 0.5 +175
Carlos Narvaez (BOS) 0.5 -225 0.5 +170
Ryan O'Hearn (BAL) 0.5 -220 0.5 +165

Red Sox vs Orioles RBI Prop Bets Today

Over Under
Wilyer Abreu (BOS) 0.5 +110 0.5 -145
Ryan Mountcastle (BAL) 0.5 +130 0.5 -165
Rafael Devers (BOS) 0.5 +145 0.5 -200
Jarren Duran (BOS) 0.5 +145 0.5 -190
Gunnar Henderson (BAL) 0.5 +145 0.5 -190

Red Sox vs Orioles Strikeout Prop Bets Today

Over Under
Dean Kremer (BAL) 4.5 -125 4.5 -105
Walker Buehler (BOS) 4.5 -120 4.5 -105

Left-handed batters are hitting .312 (39-for-125) against Dean Kremer this season — 2nd highest among qualified SPs in MLB; League Avg: .231 — third Percentile.

Dean Kremer has allowed an OPS of .909 (132 PA’s) vs left-handed batters this season — 3rd highest among qualified SPs in MLB; League Avg: .684 — fifth Percentile.

Dean Kremer has allowed a slugging percentage of .568 (71 Total Bases / 125 ABs) vs left-handed batters this season — 2nd highest among qualified SPs in MLB; League Avg: .385 — third Percentile.

Dean Kremer has a strikeout rate of just 14% (13 SO in 90 PAs) when going through the lineup the first time in a game this season — tied for 4th lowest among qualified SPs in MLB; League Avg: 24% — seventh Percentile.

Red Sox Starting Pitcher Stats & Trends

Opponents have a Hard-Hit Rate of just 15% (5/34) against Walker Buehler on breaking pitches this season — 2nd best in MLB among starting pitchers with at least 20 total IP; League Avg: 37% — 99th Percentile.

Opponents have a Hard-Hit Rate of just 13% (6/45) against Walker Buehler on non-fastballs this season — best in MLB among starting pitchers with at least 20 total IP; League Avg: 37% — 100th Percentile.

Walker Buehler has allowed an OBP of .314 (255 PA’s) with two-strikes since last season — 3rd highest in MLB among starting pitchers with at least 84 total IP; League Avg: .242 — second Percentile.

Opponents have a chase percentage of 53% (32/60) against Walker Buehler on sliders this season — highest in MLB among starting pitchers with at least 20 total IP; League Avg: 31% — 100th Percentile.

Orioles Keys to the Game vs. the Red Sox

The Orioles are just 2-14 (.125) after a win this season — 2nd lowest in MLB; League Avg: .508.

The Orioles are just 8-15 (.348) at home this season — 3rd lowest in MLB; League Avg: .563.

The Orioles are just 5-28 (.152) when scoring 4 or fewer runs this season — 2nd lowest in MLB; League Avg: .296.

The Orioles are just 16-27 (.372) when allowing 5 or more extra base hits this season — 3rd lowest in MLB; League Avg: .528.

Red Sox Keys to the Game vs. the Orioles

The Red Sox are just 6-76 (.073) when trailing entering the 7th inning since last season — 3rd lowest in MLB; League Avg: .140.

The Red Sox were just 17-33 (.340) vs top 10 scoring offenses in the 2024 season They play the Blue Jays (23rd best runs scored) today.

The Red Sox were just 5-58 (.079) when trailing entering the 7th inning in the 2024 season — 3rd lowest in MLB; League Avg: .143.

The Red Sox are 148-11 (.925) when leading entering the 8th inning since the 2023 season — tied for 5th best in MLB; League Avg: .901.

The Orioles have a winning percentage of just 35% at home this season — 3rd lowest in MLB; League Avg: 56%.

Orioles hitters have an OPS of just .556 (513 PA’s) against LHP this season — lowest in MLB; League Avg: .685.

Orioles hitters are slugging just .277 against LHP this season — lowest in MLB; League Avg: .376.

The Orioles are batting just .201 against LHP this season — tied for lowest in MLB; League Avg: .238.

Red Sox hitters have put just 30% of their swings in play on the first pitch of at-bats this season — lowest in MLB; League Avg: 36%.

Red Sox hitters struck out 506 times in 1,816 PA’s (28%) against LHP in the 2024 season — highest in MLB; League Avg: 23%.

Red Sox hitters put just 32% of their swings in play against LHP in the 2024 season — lowest in MLB; League Avg: 37%.

Red Sox hitters have struck out in 25% of it’s PA’s against LHP since the 2023 season — 3rd highest in MLB; League Avg: 23%.

Orioles pitchers have walked 13% of batters when facing the leadoff batter in the inning this season — highest in MLB; League Avg: 8%.

Opponents have a miss rate of just 23% against Orioles pitchers this season — 3rd lowest in MLB; League Avg: 25%.

Orioles pitchers have an ERA of 6.32 (208.0 IP) at home this season — highest in MLB; League Avg: 3.85.

Orioles pitchers have an ERA of 6.27 (116.1 IP) over the last 14 days — 2nd highest in MLB; League Avg: 3.99.

Opponents had a miss rate of just 24% against Red Sox pitchers in the 2024 season — tied for 2nd lowest in MLB; League Avg: 25%.

Opponents have a groundball rate of 44% against Red Sox pitchers since the 2023 season — 5th highest in MLB; League Avg: 43%.

Opponents have a miss rate of just 24% against Red Sox pitchers since last season — 3rd lowest in MLB; League Avg: 25%.

Red Sox pitchers had a strikeout rate of just 19% with runners in scoring position in the 2024 season — 3rd lowest in MLB; League Avg: 22%.

More MLB Reading:


Bet now on Orioles vs Red Sox and all games with BetMGM


Bet on MLB Odds at BetMGM

Sportsbook promos are always available at BetMGM. For new customers, check out the sportsbook welcome offer and BetMGM Refer a Friend. For existing customers, there are Odds Boosts, Parlay Boosts, contests and more.

Split First Bet Offer FBO March Matchups 1080x610
About the Author

BetMGM Betting

Read More @BETMGM

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.