Padres vs Cubs Prediction, Odds & Player Prop Bets Today – MLB, May 8

FILE - Chicago Cubs' Cody Bellinger watches his home run during the third inning of a baseball game against the New York Yankees, July 7, 2023, in New York. There are still some premium free agents available for Major League Baseball teams as the calendar nears March. Two-time Cy Young Winner Blake Snell, six-time All-Star J.D. Martinez and former MVP Cody Bellinger are among the players who haven't found a home. (AP Photo/Frank Franklin II, File)
(AP Photo/Frank Franklin II, File)
  • The Padres are -125 favorites vs the Cubs
  • Padres vs Cubs Over / Under today: 8 Runs
  • Padres / Cubs TV Channel: MARQ | PDTV

The San Diego Padres (-125) visit Wrigley Field to take on the Chicago Cubs (+105) on Wednesday, May 8, 2024. First pitch is scheduled for 2:20pm EDT in Chicago, IL.

This season, the Padres are 19-20 against the spread (ATS), while the Cubs are 23-14 ATS.

Padres vs Cubs Starting Pitchers Today:

  • Padres starting pitcher: Dylan Cease 4-2, 2.55 ERA
  • Cubs starting pitcher: Hayden Wesneski 2-0, 0.54 ERA

Padres vs. Cubs Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Padres-1.5 +135O 7.5 -110-125
Cubs +1.5 -165U 7.5 -110+105

Padres vs Cubs Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Wednesday‘s MLB game with 55.3% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Padres players for Wednesday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Bets Today:

  • Ha-Seong Kim has hit the Home Runs Over in 4 of his last 15 away games (+25.50 Units / 170% ROI)
  • Jurickson Profar has hit the Hits Over in 26 of his last 35 games (+13.60 Units / 21% ROI)
  • Manny Machado has hit the Singles Over in 18 of his last 24 games (+12.10 Units / 44% ROI)
  • Jackson Merrill has hit the Runs Under in 16 of his last 19 games (+10.75 Units / 32% ROI)
  • Jurickson Profar has hit the Total Bases Over in 10 of his last 12 games (+9.60 Units / 62% ROI)

And here are some favorite MLB player prop bets for Cubs players for Wednesday‘s game, looking at profitable historical betting trends:

Best Cubs Player Prop Best Bets Today:

  • Christopher Morel has hit the Home Runs Over in 5 of his last 9 games (+18.95 Units / 211% ROI)
  • Ian Happ has hit the Hits Runs and RBIs Under in 19 of his last 24 games (+13.40 Units / 47% ROI)
  • Nico Hoerner has hit the Hits Over in 10 of his last 13 games at home (+11.25 Units / 58% ROI)
  • Ian Happ has hit the Runs Under in 18 of his last 23 games (+10.90 Units / 31% ROI)
  • Cody Bellinger has hit the RBIs Over in his last 7 games (+10.35 Units / 148% ROI)
  • The San Diego Padres have hit the Moneyline in 20 of their last 27 games (+12.45 Units / 30% ROI)
  • The San Diego Padres have hit the Game Total Under in 10 of their last 11 games (+8.95 Units / 72% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Moneyline in 12 of their last 16 games (+8.80 Units / 33% ROI)
  • The San Diego Padres have covered the 1st Five Innings (F5) Run Line in 12 of their last 16 games (+7.09 Units / 36% ROI)
  • The San Diego Padres have covered the Run Line in 17 of their last 27 games (+6.75 Units / 20% ROI)
  • The Chicago Cubs have hit the 1st Five Innings (F5) Team Total Over in 38 of their last 66 games (+9.21 Units / 12% ROI)
  • The Chicago Cubs have hit the Game Total Under in 21 of their last 32 games (+8.75 Units / 25% ROI)
  • The Chicago Cubs have hit the Moneyline in 23 of their last 34 games at home (+7.75 Units / 15% ROI)
  • The Chicago Cubs have hit the Team Total Over in 35 of their last 61 games at home (+6.79 Units / 10% ROI)
  • The Chicago Cubs have covered the Run Line in 19 of their last 34 games at home (+6.75 Units / 18% ROI)

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are 20-19 against the Run Line (+3.05 Units / 6.44% ROI).

  • 19-20 when betting on the Moneyline for -3.25 Units / -6.75% ROI
  • 21-17 when betting on the total runs Over for +2.5 Units / 5.87% ROI
  • 17-21 when betting on the total runs Under for -6.2 Units / -14.35% ROI

Cubs Against the Spread (ATS) Record

Against the spread this season, the Cubs are 23-14 against the Run Line (+6.55 Units / 12.46% ROI).

  • 22-15 when betting on the Moneyline for +8.2 Units / 18.12% ROI
  • 16-21 when betting on the total runs Over for -7.25 Units / -17.73% ROI
  • 21-16 when betting on the total runs Under for +3.45 Units / 8.51% ROI

Cubs vs Padres Home Run Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +425 0.5 -600
Christopher Morel (CHC) 0.5 +475 0.5 -650
Patrick Wisdom (CHC) 0.5 +500 0.5 -700
Manny Machado (SD) 0.5 +500 0.5 -700
Cody Bellinger (CHC) 0.5 +525 0.5 -750

Cubs vs Padres Total Hits Prop Bets Today

Over Under
Jake Cronenworth (SD) 0.5 -275 0.5 +200
Nico Hoerner (CHC) 0.5 -250 0.5 +190
Fernando Tatis Jr. (SD) 0.5 -250 0.5 +175
Jackson Merrill (SD) 0.5 -250 0.5 +190
Jurickson Profar (SD) 0.5 -225 0.5 +175

Cubs vs Padres RBI Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +140 0.5 -190
Cody Bellinger (CHC) 0.5 +170 0.5 -225
Jurickson Profar (SD) 0.5 +175 0.5 -250
Fernando Tatis Jr. (SD) 0.5 +175 0.5 -250
Jackson Merrill (SD) 0.5 +175 0.5 -250

Cubs vs Padres Strikeout Prop Bets Today

Over Under
Hayden Wesneski (CHC) 3.5 -110 3.5 -120
Dylan Cease (SD) 7.5 +120 7.5 -160

Dylan Cease has allowed an OBP of just .212 (160 PAs) this season — tied for second best among qualified SPs– 99th Percentile. He allowed an OBP of .332 (783 PAs) last season — third worst among qualified SPs– sixth Percentile.

Dylan Cease has allowed an OPS of just .280 (86 PA’s) against right-handed batters this season — best among qualified SPs in MLB; League Avg: .667 — 100th Percentile.

Dylan Cease has allowed an OBP of just .141 (85 PA’s) against right-handed batters this season — best among qualified SPs in MLB; League Avg: .292 — 100th Percentile.

Dylan Cease has allowed an OBP of just .161 (62 PA’s) when going through the lineup the second time in a game this season — 2nd best among qualified SPs in MLB; League Avg: .288 — 98th Percentile.

Cubs Starting Pitcher Stats & Trends

Hayden Wesneski has thrown at least two strikes in his first three pitches to 81% (34/42) of opposing batters this season — 2nd highest in MLB among starting pitchers with at least 13 total IP; League Avg: 64% — 99th Percentile.

Hayden Wesneski has allowed no extra-base hits in his last 15.2 innings pitched — Jhoan Duran has the longest active streak at 25.1.

Hayden Wesneski has allowed a slugging percentage of just .167 (10 Total Bases / 60 ABs) this season — best in MLB among starting pitchers with at least 13 total IP; League Avg: .390 — 100th Percentile.

Hayden Wesneski has allowed an OPS of just .357 (63 PA’s) this season — best in MLB among starting pitchers with at least 13 total IP; League Avg: .696 — 100th Percentile.

Padres Keys to the Game vs. the Cubs

The Padres are just 5-17 (.227) after a win as underdogs since the 2023 season — lowest in MLB; League Avg: .427.

The Padres are just 7-136 (.049) when trailing entering the 8th inning since the 2022 season — tied for lowest in MLB; League Avg: .094.

The Padres are just 17-32 (.347) after a win as underdogs since the 2022 season — 3rd lowest in MLB; League Avg: .415.

The Padres are just 88-14 (.863) when leading entering the 8th inning since the 2023 season — 5th lowest in MLB; League Avg: .898.

Cubs Keys to the Game vs. the Padres

The Cubs are 38-21 (.644) after a win as favorites since the 2023 season — 5th best in MLB; League Avg: .576.

The Cubs are just 9-14 (.391) when tied entering the 7th inning since the 2023 season — tied for 4th lowest in MLB; League Avg: .500.

The Cubs are just 38-39 (.494) after a loss as favorites since the 2022 season — 4th lowest in MLB; League Avg: .587.

The Cubs are just 16-28 (.364) after a win as underdogs since the 2023 season — 5th lowest in MLB; League Avg: .427.

Padres hitters have a swing rate of just 46% against LHP since the 2022 season — tied for lowest in MLB; League Avg: 48%.

The Padres are batting .288 on the road this season — best in MLB; League Avg: .239.

Padres hitters have 39 extra-base hits out of 73 total hits (53%) with the pitcher behind in the count this season — best in MLB; League Avg: 39%.

The Padres are batting .186 on pitches out of the zone this season — tied for 3rd best in MLB; League Avg: .156.

Cubs hitters are slugging .493 in lefty-lefty matchups since last season — 2nd best in MLB; League Avg: .373.

Cubs hitters have an OPS of .792 (1,985 PA’s) against LHP since last season — 3rd best in MLB; League Avg: .735.

Cubs hitters have an OPS of .848 (388 PA’s) in lefty-lefty matchups since last season — 2nd best in MLB; League Avg: .686.

Cubs hitters have an OBP of .349 (668 PA’s) at home this season — 2nd best in MLB; League Avg: .315.

Padres pitchers allowed an average Exit Velocity of 87.9 MPH (3,921 batted balls) in the 2023 season — best in MLB; League Avg: 89.0.

The Padres pitchers allowed an average Exit Velocity of just 87.9 MPH in the 2023 season (3,921 balls in play) — best in MLB; League Avg: 89.0

Opponents have a groundball batting average of just .197 against Padres pitchers with the shift since the 2022 season — best in MLB; League Avg: .230.

Padres pitchers have allowed a run 46% of the time after an opposing score this season — highest in MLB; League Avg: 29%.

The Cubs pitchers have allowed their opponents to score first in just 28% of their games at home this season — lowest in MLB; League Avg: 57%.

Cubs pitchers have induced opposing hitters to ground into just 17 double plays in 287 opportunities (6%) this season — tied for lowest in MLB; League Avg: 10%.

Cubs pitchers allowed an average Exit Velocity of 88.3 MPH (4,045 batted balls) in the 2023 season — 2nd best in MLB; League Avg: 89.0.

The Cubs pitchers have allowed division opponents to score first in just 42% of their games since the 2022 season — 3rd lowest in MLB; League Avg: 50%.

Cubs vs. Padres Injuries Tonight That May Affect Prop Bets 

  • Patrick Wisdom (Chicago Cubs): Back, 10-Day IL
  • Justin Steele (Chicago Cubs): Hamstring, 15-Day IL
  • Brennen Davis (Chicago Cubs): Undisclosed, Out
  • Tyler Duffey (Chicago Cubs): Back, Day-To-Day
  • Jameson Taillon (Chicago Cubs): Back, 15-Day IL
  • Caleb Kilian (Chicago Cubs): Shoulder, 60-Day IL
  • Glenn Otto (San Diego Padres): Shoulder, 15-Day IL
  • Reiss Knehr (San Diego Padres): Elbow, Out
  • Drew Carlton (San Diego Padres): Elbow, Out
  • Luis Patino (San Diego Padres): Elbow, 15-Day IL
  • Tucupita Marcano (San Diego Padres): Knee, 10-Day IL

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.