Red Sox vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Apr 24

Cleveland Guardians catcher Bo Naylor sits near the bullpen during spring training baseball workouts in Goodyear, Ariz., Friday, Feb. 16, 2024.
(AP Photo/Carolyn Kaster)
  • The Guardians are -140 favorites vs the Red Sox
  • Red Sox vs Guardians Over / Under today: 8 Runs
  • Red Sox / Guardians TV Channel: BSGL | NES+

The Boston Red Sox (+120) visit Progressive Field to take on the Cleveland Guardians (-140) on Wednesday, April 24, 2024. First pitch is scheduled for 6:10pm EDT in Cleveland, OH.

This season, the Red Sox are 13-11 against the spread (ATS), while the Guardians are 15-6 ATS.

Red Sox vs Guardians Starting Pitchers Today:

  • Red Sox starting pitcher: Cooper Criswell 0-1, 4.50 ERA
  • Guardians starting pitcher: Carlos Carrasco 1-1, 3.44 ERA

Red Sox vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Red Sox+1.5 -175O 7.5 -105+120
Guardians -1.5 +145U 7.5 -115-140

Red Sox vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Wednesday‘s MLB game with 53.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Red Sox players for Wednesday‘s game, looking at profitable historical betting trends:

Best Red Sox Player Prop Bets Today:

  • player high – away 

And here are some favorite MLB player prop bets for Guardians players for Wednesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • player  high – home
  • The Boston Red Sox have hit the Game Total Under in 15 of their last 19 games (+10.60 Units / 50% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Team Total Under in 37 of their last 66 away games (+7.03 Units / 9% ROI)
  • The Boston Red Sox have hit the Team Total Under in 34 of their last 61 away games (+5.05 Units / 7% ROI)
  • The Boston Red Sox have covered the 1st Five Innings (F5) Run Line in 5 of their last 7 away games (+2.95 Units / 38% ROI)
  • The Boston Red Sox have hit the 1st Five Innings (F5) Moneyline in 3 of their last 6 away games (+1.53 Units / 24% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 47 of their last 72 games at home (+20.80 Units / 26% ROI)
  • The Cleveland Guardians have covered the Run Line in 64 of their last 120 games (+6.20 Units / 4% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Over in 20 of their last 34 games (+4.72 Units / 12% ROI)
  • The Cleveland Guardians have hit the Moneyline in 35 of their last 62 games at home (+4.25 Units / 5% ROI)

Red Sox Against the Spread (ATS) Record

Against the spread this season, the Red Sox are 14-10 against the Run Line (+0 Units / 0% ROI).

  • 13-11 when betting on the Moneyline for +0 Units / 0% ROI
  • 0-0 when betting on the total runs Over for +0 Units / 0% ROI
  • 0-0 when betting on the total runs Under for +0 Units / 0% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 15-6 against the Run Line (+0 Units / 0% ROI).

  • 16-5 when betting on the Moneyline for +0 Units / 0% ROI
  • 0-0 when betting on the total runs Over for +0 Units / 0% ROI
  • 0-0 when betting on the total runs Under for +0 Units / 0% ROI

Guardians vs Red Sox Home Run Prop Bets Today

Over Under
Rafael Devers (BOS) 0.5 +400 0.5 -550
Tyler O'Neill (BOS) 0.5 +500 0.5 -750
Josh Naylor (CLE) 0.5 +625 0.5 -1000
Jose Ramirez (CLE) 0.5 +650 0.5 -1100
Bo Naylor (CLE) 0.5 +650 0.5 -1000

Guardians vs Red Sox Total Hits Prop Bets Today

Over Under
Andres Gimenez (CLE) 0.5 -250 0.5 +190
Tyler O'Neill (BOS) 0.5 -225 0.5 +160
Tyler Freeman (CLE) 0.5 -200 0.5 +155
Wilyer Abreu (BOS) 0.5 -190 0.5 +145
Brayan Rocchio (CLE) 0.5 -175 0.5 +135

Guardians vs Red Sox RBI Prop Bets Today

Over Under
Josh Naylor (CLE) 0.5 +115 0.5 -155
Jose Ramirez (CLE) 0.5 +120 0.5 -155
Rafael Devers (BOS) 0.5 +150 0.5 -200
Tyler O'Neill (BOS) 0.5 +155 0.5 -210
Wilyer Abreu (BOS) 0.5 +165 0.5 -225

Guardians vs Red Sox Strikeout Prop Bets Today

Over Under

Opponents have a miss rate of just 4% (1/22) against Cooper Criswell over the past seven days (1 games) — tied for 3rd lowest in AL over the last week; League Avg: 28% — fourth Percentile.

Guardians Starting Pitcher Stats & Trends

Carlos Carrasco has allowed a slugging percentage of .761 (102 Total Bases / 134 ABs) on inside fastballs since the 2022 season — highest in MLB among starting pitchers with at least 138 total IP; League Avg: .429 — 0 Percentile.

Opponents are hitting .479 (81-for-169) against Carlos Carrasco when he’s behind in the count since the 2022 season — highest in MLB among starting pitchers with at least 138 total IP; League Avg: .337 — first Percentile.

Opponents are hitting .410 (55-for-134) against Carlos Carrasco’s inside fastball since the 2022 season — highest in MLB among starting pitchers with at least 138 total IP; League Avg: .262 — 0 Percentile.

Carlos Carrasco has allowed a slugging percentage of .876 (148 Total Bases / 169 ABs) when behind in the count since the 2022 season — highest in MLB among starting pitchers with at least 138 total IP; League Avg: .597 — first Percentile.

Red Sox Keys to the Game vs. the Guardians

The Red Sox are just 3-148 (.020) when trailing entering the 9th inning since the 2022 season — 3rd lowest in MLB; League Avg: .049.

The Red Sox are just 14-21 (.400) when tied entering the 8th inning since the 2022 season — 4th lowest in MLB; League Avg: .500.

The Red Sox are 35-38 (.479) after a win as underdogs since the 2022 season — 5th best in MLB; League Avg: .412.

The Red Sox are just 35-65 (.350) after a loss as underdogs since the 2022 season — 3rd lowest in MLB; League Avg: .410.

Guardians Keys to the Game vs. the Red Sox

The Guardians are 35-119 (.227) when trailing entering the 7th inning since the 2022 season — best in MLB; League Avg: .132.

The Guardians are 24-126 (.160) when trailing entering the 8th inning since the 2022 season — 2nd best in MLB; League Avg: .094.

The Guardians are just 9-16 (.360) when tied entering the 7th inning since the 2023 season — 2nd lowest in MLB; League Avg: .500.

The Guardians are 12-66 (.154) when trailing entering the 8th inning since the 2023 season — 5th best in MLB; League Avg: .101.

Red Sox hitters have 74 strikeouts in 244 PA’s (30%) against LHP this season — highest in MLB; League Avg: 22%.

The Red Sox are batting .271 at home since the 2022 season — 2nd best in MLB; League Avg: .248.

Red Sox hitters are slugging .793 on the first pitch of at-bats this season — 2nd best in MLB; League Avg: .559.

Red Sox hitters have a groundball batting average of .262 against the shift since the 2022 season — best in MLB; League Avg: .231.

Guardians hitters have just 1,715 strikeouts in 9,431 PA’s (18%) against RHP since the 2022 season — best in MLB; League Avg: 23%.

Guardians hitters are slugging just .364 against LHP since the 2022 season — tied for 2nd lowest in MLB; League Avg: .407.

Guardians hitters have put 42% of balls in play to the right side of the field since last season — highest in MLB; League Avg: 37%.

Guardians hitters have put just 34% of balls in play to the left side of the field since last season — lowest in MLB; League Avg: 39%.

Opponents have a groundball rate of 45% against Red Sox pitchers since last season — tied for 5th highest in MLB; League Avg: 43%.

Red Sox pitchers have a strikeout rate of 30% when going through the lineup the third time in a game this season — best in MLB; League Avg: 19%.

The Red Sox have allowed 2.29 runs per game (32/14) on the road this season — best in MLB; League Avg: 4.28.

Red Sox pitchers have an ERA of 1.65 (125.1 IP) on the road this season — best in MLB; League Avg: 3.98.

Opponents have a miss rate of 30% against Guardians pitchers this season — best in MLB; League Avg: 25%.

Guardians pitchers have a strikeout rate of 30% with runners in scoring position this season — best in MLB; League Avg: 21%.

Guardians pitchers have a strikeout rate of 32% over the past seven days (6 games) — best in MLB; League Avg: 22%.

Guardians pitchers have a strikeout rate of 26% this season — 2nd best in MLB; League Avg: 22%.

Guardians vs. Red Sox Injuries Tonight That May Affect Prop Bets 

  • Daniel Espino (Cleveland Guardians): Shoulder, Out
  • Gavin Williams (Cleveland Guardians): Elbow, 15-Day IL
  • Ben Lively (Cleveland Guardians): Illness, 15-Day IL
  • Luis Ortiz (Cleveland Guardians): Ankle, 15-Day IL
  • Xzavion Curry (Cleveland Guardians): Illness, 15-Day IL
  • Joey Cantillo (Cleveland Guardians): Hamstring, Out
  • Angel Martinez (Cleveland Guardians): Foot, 10-Day IL
  • Sam Hentges (Cleveland Guardians): Finger, 15-Day IL
  • Trevor Stephan (Cleveland Guardians): Elbow, 60-Day IL
  • George Valera (Cleveland Guardians): Hamstring, Out
  • James Karinchak (Cleveland Guardians): Shoulder, 60-Day IL
  • Wyatt Mills (Boston Red Sox): Elbow, 60-Day IL
  • Vaughn Grissom (Boston Red Sox): Hamstring, 10-Day IL
  • Michael Fulmer (Boston Red Sox): Elbow, 60-Day IL
  • Zack Kelly (Boston Red Sox): Oblique, Day-To-Day
  • Bryan Mata (Boston Red Sox): Hamstring, 15-Day IL
  • Chris Murphy (Boston Red Sox): Elbow, 60-Day IL
  • Kenley Jansen (Boston Red Sox): Back, Day-To-Day
  • Brandon Walter (Boston Red Sox): Shoulder, 7-Day IL
  • Lucas Giolito (Boston Red Sox): Elbow, 60-Day IL
  • Rob Refsnyder (Boston Red Sox): Toe, 10-Day IL
  • Yu Chang (Boston Red Sox): Oblique, Out

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.