- The St. Louis Cardinals are -190 favorites vs the Chicago White Sox
- St. Louis Cardinals vs Chicago White Sox Over / Under today: 8.5 Runs
- St. Louis Cardinals / Chicago White Sox TV Channel: FDMW | CHSN
The St. Louis Cardinals (-175) visit Rate Field to take on the Chicago White Sox (+145) on Wednesday, June 18, 2025. First pitch is scheduled for 7:40pm EDT in Chicago, IL, IL.
This season, the St. Louis Cardinals are 38-35 against the spread (ATS), while the Chicago White Sox are 42-31 ATS.
St. Louis Cardinals vs Chicago White Sox Starting Pitchers Today:
- St. Louis Cardinals starting pitcher: , ERA
- Chicago White Sox starting pitcher: , ERA
St. Louis Cardinals vs. Chicago White Sox Odds, Run Line, Over/Under & Moneyline
| Spread | Over / Under | Moneyline | |
| St. Louis Cardinals | -1.5 -110 | O 8.5 -110 | -175 |
| Chicago White Sox | +1.5 -110 | U 8.5 -110 | +145 |
St. Louis Cardinals vs Chicago White Sox Prediction for Today’s Game
Based on recent trends the model predicts the will win Wednesday‘s MLB game with confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.
Bet now on St. Louis Cardinals vs Chicago White Sox and all games with BetMGM
We’ve highlighted some favorite MLB player prop bets for St. Louis Cardinals players for Wednesday‘s game, looking at profitable historical betting trends:
Best St. Louis Cardinals Player Prop Bets Today:
- Alec Burleson has hit the Total Bases Over in 20 of his last 25 games (+17.40 Units / 51% ROI)
- Willson Contreras has hit the RBIs Over in 11 of his last 15 games (+13.15 Units / 88% ROI)
- Sonny Gray has hit the Walks Allowed Under in 12 of his last 15 games (+10.10 Units / 60% ROI)
- Ivan Herrera has hit the Runs Under in 16 of his last 20 games (+9.70 Units / 30% ROI)
- Lars Nootbaar has hit the Hits Runs and RBIs Under in 15 of his last 20 games (+9.55 Units / 41% ROI)
And here are some favorite MLB player prop bets for Chicago White Sox players for Wednesday‘s game, looking at profitable historical betting trends:
Best Chicago White Sox Player Prop Best Bets Today:
- Chase Meidroth has hit the Hits Runs and RBIs Over in 15 of his last 20 games at home (+11.10 Units / 53% ROI)
- Chase Meidroth has hit the Total Bases Over in 12 of his last 15 games at home (+10.10 Units / 43% ROI)
- Andrew Benintendi has hit the RBIs Under in his last 9 games (+9.00 Units / 40% ROI)
- Chase Meidroth has hit the Singles Over in 17 of his last 25 games at home (+8.85 Units / 31% ROI)
- Andrew Benintendi has hit the Hits Over in 19 of his last 25 games at home (+8.55 Units / 19% ROI)
St. Louis Cardinals Best Bets Today:
- The St. Louis Cardinals have covered the Run Line in 26 of their last 40 games (+13.25 Units / 26% ROI)
- The St. Louis Cardinals have hit the Moneyline in 29 of their last 50 games (+7.95 Units / 14% ROI)
- The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 15 of their last 23 away games (+6.95 Units / 26% ROI)
- The St. Louis Cardinals have hit the 1st Five Innings (F5) Team Total Under in 22 of their last 36 away games (+5.86 Units / 13% ROI)
- The St. Louis Cardinals have hit the Team Total Under in 9 of their last 13 away games (+4.90 Units / 33% ROI)
Chicago White Sox Best Bets Today:
- The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 25 of their last 35 games at home (+13.60 Units / 32% ROI)
- The Chicago White Sox have covered the Run Line in 31 of their last 49 games (+9.70 Units / 16% ROI)
- The Chicago White Sox have hit the 1st Five Innings (F5) Moneyline in 16 of their last 35 games at home (+9.55 Units / 26% ROI)
- The Chicago White Sox have hit the Team Total Over in 16 of their last 22 games at home (+9.45 Units / 37% ROI)
- The Chicago White Sox have hit the Moneyline in 12 of their last 21 games at home (+7.79 Units / 37% ROI)
St. Louis Cardinals Against the Spread (ATS) Record
Against the spread this season, the St. Louis Cardinals are 41-32 against the Run Line (+4.45 Units / 4.46% ROI).
- 38-35 when betting on the Moneyline for +2.3 Units / 2.76% ROI
- 39-31 when betting on the total runs Over for +4.8 Units / 5.98% ROI
- 31-39 when betting on the total runs Under for -12.05 Units / -15% ROI
Chicago White Sox Against the Spread (ATS) Record
Against the spread this season, the Chicago White Sox are 42-31 against the Run Line (+6.5 Units / 7.41% ROI).
- 23-50 when betting on the Moneyline for -14.46 Units / -19.78% ROI
- 34-36 when betting on the total runs Over for -5.75 Units / -7.16% ROI
- 36-34 when betting on the total runs Under for -1.6 Units / -1.99% ROI
Chicago White Sox vs St. Louis Cardinals Home Run Prop Bets Today
| Over | Under | |
|---|---|---|
| Nolan Gorman (STL) | 0.5 +375 | 0.5 -500 |
| Willson Contreras (STL) | 0.5 +375 | 0.5 -500 |
| Lars Nootbaar (STL) | 0.5 +400 | 0.5 -550 |
| Alec Burleson (STL) | 0.5 +400 | 0.5 -550 |
| Miguel Vargas (CWS) | 0.5 +500 | 0.5 -700 |
Chicago White Sox vs St. Louis Cardinals Total Hits Prop Bets Today
| Over | Under | |
|---|---|---|
| Masyn Winn (STL) | 0.5 -250 | 0.5 +185 |
| Alec Burleson (STL) | 0.5 -250 | 0.5 +180 |
| Willson Contreras (STL) | 0.5 -235 | 0.5 +180 |
| Chase Meidroth (CWS) | 0.5 -220 | 0.5 +165 |
| Nolan Arenado (STL) | 0.5 -210 | 0.5 +155 |
Chicago White Sox vs St. Louis Cardinals RBI Prop Bets Today
| Over | Under | |
|---|---|---|
| Willson Contreras (STL) | 0.5 +140 | 0.5 -185 |
| Alec Burleson (STL) | 0.5 +140 | 0.5 -185 |
| Ivan Herrera (STL) | 0.5 +160 | 0.5 -210 |
| Nolan Arenado (STL) | 0.5 +170 | 0.5 -225 |
| Masyn Winn (STL) | 0.5 +175 | 0.5 -235 |
Chicago White Sox vs St. Louis Cardinals Strikeout Prop Bets Today
| Over | Under | |
|---|---|---|
| Sonny Gray (STL) | 6.5 +120 | 6.5 -155 |
| Sean Burke (CWS) | 4.5 +145 | 4.5 -190 |
St. Louis Cardinals Starting Pitcher Stats & Trends
starting pitcher – away
Chicago White Sox Starting Pitcher Stats & Trends
starting pitcher – home
St. Louis Cardinals Keys to the Game vs. the Chicago White Sox
keys to the game – away
Chicago White Sox Keys to the Game vs. the St. Louis Cardinals
keys to the game – home
St. Louis Cardinals Hitting Stats & Trends
team hitters – away
Chicago White Sox Hitting Stats & Trends
team hitters – home
St. Louis Cardinals Pitching Stats & Trends
team pitchers – away
Chicago White Sox Pitching Stats & Trends
team pitchers – home
More MLB Reading:
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