Twins vs Guardians Prediction, Odds & Player Prop Bets Today – MLB, Sep 17

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Cleveland Guardians catcher Bo Naylor sits near the bullpen during spring training baseball workouts in Goodyear, Ariz., Friday, Feb. 16, 2024.
(AP Photo/Carolyn Kaster)
BetMGM Betting @BETMGM Sep 17, 2024, 11:02 AM
  • The Guardians are -125 favorites vs the Twins
  • Twins vs Guardians Over / Under today: 8.5 Runs
  • Twins / Guardians TV Channel: BSGL | BSNO

The Minnesota Twins (+105) visit Progressive Field to take on the Cleveland Guardians (-125) on Tuesday, September 17, 2024. First pitch is scheduled for 6:40pm EDT in Cleveland, OH.

This season, the Twins are 79-71 against the spread (ATS), while the Guardians are 77-74 ATS.

Twins vs Guardians Starting Pitchers Today:

  • Twins starting pitcher: Zebby Matthews 1-3, 7.11 ERA
  • Guardians starting pitcher: Gavin Williams 3-9, 5.21 ERA

Twins vs. Guardians Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Twins+1.5 -210O 8 -105+105
Guardians -1.5 +170U 8 -115-125

Twins vs Guardians Prediction for Today’s Game

Based on recent trends the model predicts the Guardians will win Tuesday‘s MLB game with 52.1% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


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We’ve highlighted some favorite MLB player prop bets for Twins players for Tuesday‘s game, looking at profitable historical betting trends:

Best Twins Player Prop Bets Today:

  • Jose Miranda has hit the RBIs Under in 16 of his last 17 away games (+14.05 Units / 38% ROI)
  • Kyle Farmer has hit the Home Runs Over in 2 of his last 4 games (+12.60 Units / 315% ROI)
  • Royce Lewis has hit the Runs Under in 15 of his last 18 games (+10.60 Units / 41% ROI)
  • Matt Wallner has hit the Total Bases Over in 27 of his last 40 games (+10.55 Units / 20% ROI)
  • Royce Lewis has hit the Hits Runs and RBIs Under in 13 of his last 18 games (+8.25 Units / 41% ROI)

And here are some favorite MLB player prop bets for Guardians players for Tuesday‘s game, looking at profitable historical betting trends:

Best Guardians Player Prop Best Bets Today:

  • Brayan Rocchio has hit the Home Runs Over in 2 of his last 11 games (+14.50 Units / 132% ROI)
  • Lane Thomas has hit the Runs Under in 19 of his last 25 games at home (+10.90 Units / 28% ROI)
  • Jose Ramirez has hit the RBIs Under in 16 of his last 19 games (+10.80 Units / 33% ROI)
  • Jose Ramirez has hit the Hits Runs and RBIs Over in 19 of his last 25 games at home (+10.80 Units / 32% ROI)
  • Lane Thomas has hit the Hits Under in 13 of his last 21 games at home (+10.55 Units / 47% ROI)
  • The Minnesota Twins have hit the Game Total Over in 48 of their last 84 games (+14.20 Units / 15% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Team Total Under in 14 of their last 19 games (+9.45 Units / 42% ROI)
  • The Minnesota Twins have hit the 1st Five Innings (F5) Moneyline in 13 of their last 24 away games (+2.10 Units / 7% ROI)
  • The Minnesota Twins have covered the 1st Five Innings (F5) Run Line in 7 of their last 12 away games (+1.70 Units / 12% ROI)
  • The Minnesota Twins have covered the Run Line in 3 of their last 6 games (+0.05 Units / 1% ROI)
  • The Cleveland Guardians have hit the Game Total Under in 35 of their last 59 games (+12.90 Units / 20% ROI)
  • The Cleveland Guardians have hit the Moneyline in 87 of their last 151 games (+12.22 Units / 6% ROI)
  • The Cleveland Guardians have covered the Run Line in 35 of their last 69 games at home (+11.75 Units / 15% ROI)
  • The Cleveland Guardians have hit the 1st Five Innings (F5) Team Total Under in 8 of their last 12 games (+3.85 Units / 27% ROI)

Twins Against the Spread (ATS) Record

Against the spread this season, the Twins are 68-82 against the Run Line (-18.4 Units / -9.71% ROI).

  • 79-71 when betting on the Moneyline for -11.25 Units / -5.25% ROI
  • 76-65 when betting on the total runs Over for +4.8 Units / 2.93% ROI
  • 65-76 when betting on the total runs Under for -18.85 Units / -11.48% ROI

Guardians Against the Spread (ATS) Record

Against the spread this season, the Guardians are 77-74 against the Run Line (+5.45 Units / 2.88% ROI).

  • 87-64 when betting on the Moneyline for +12.22 Units / 6.24% ROI
  • 67-74 when betting on the total runs Over for -14.85 Units / -8.9% ROI
  • 74-67 when betting on the total runs Under for +0.35 Units / 0.21% ROI

Guardians vs Twins Home Run Prop Bets Today

Over Under
Matt Wallner (MIN) 0.5 +310 0.5 -400
Byron Buxton (MIN) 0.5 +333 0.5 -450
Royce Lewis (MIN) 0.5 +400 0.5 -550
Kyle Manzardo (CLE) 0.5 +425 0.5 -650
Jhonkensy Noel (CLE) 0.5 +450 0.5 -650

Guardians vs Twins Total Hits Prop Bets Today

Over Under
Josh Naylor (CLE) 0.5 -250 0.5 +185
Jose Ramirez (CLE) 0.5 -250 0.5 +185
Carlos Correa (MIN) 0.5 -225 0.5 +165
Royce Lewis (MIN) 0.5 -210 0.5 +160
Lane Thomas (CLE) 0.5 -185 0.5 +135

Guardians vs Twins RBI Prop Bets Today

Over Under
Josh Naylor (CLE) 0.5 +130 0.5 -165
Jose Ramirez (CLE) 0.5 +140 0.5 -190
Royce Lewis (MIN) 0.5 +160 0.5 -210
Byron Buxton (MIN) 0.5 +165 0.5 -225
Matt Wallner (MIN) 0.5 +175 0.5 -225

Guardians vs Twins Strikeout Prop Bets Today

Over Under
Gavin Williams (CLE) 5.5 -160 5.5 +125
Zebby Matthews (MIN) 4.5 +130 4.5 -165

Zebby Matthews has allowed at least one HR in each of his last four games dating back to August 25th — Bobby Miller has the longest active streak at 11.

Zebby Matthews has allowed a slugging percentage of .500 (10 Total Bases / 20 ABs) with two-strikes this month (2 games) — tied for 8th highest in MLB among starting pitchers with at least 4 total IP; League Avg: .251 — seventh Percentile.

Zebby Matthews has allowed a slugging percentage of .750 (12 Total Bases / 16 ABs) when going through the lineup the second time in a game this month (2 games) — tied for 5th highest in MLB among starting pitchers with at least 4 total IP; League Avg: .385 — fourth Percentile.

Opponents are hitting .350 (7-for-20) against Zebby Matthews with two-strikes this month (2 games) — 3rd highest in MLB among starting pitchers with at least 4 total IP; League Avg: .165 — second Percentile.

Guardians Starting Pitcher Stats & Trends

Gavin Williams has walked 5 of 25 batters (20%) when going through the lineup the first time in a game this month (3 games) — 2nd highest among qualified SPs in MLB; League Avg: 7% — second Percentile.

10 of Gavin Williams’ 31 breaking pitch strikeouts (32%) have been backdoor this season — 5th highest in MLB among starting pitchers with at least 60 total IP; League Avg: 14% — 96th Percentile.

20 of Gavin Williams’ 71 breaking pitch strikeouts (28%) have been backdoor since last season — 4th highest in MLB among starting pitchers with at least 124 total IP; League Avg: 14% — 96th Percentile.

Opponents batted .333 (7-for-21) against Gavin Williams in his last start — tied for 6th highest in MLB over the last week; League Avg: .224 — eighth Percentile.

Twins Keys to the Game vs. the Guardians

The Twins are 137-2 (.986) when leading entering the 9th inning since the 2023 season — best in MLB; League Avg: .949.

The Twins are 205-5 (.976) when leading entering the 9th inning since the 2022 season — 2nd best in MLB; League Avg: .950.

The Twins are 26-103 (.202) when trailing entering the 7th inning since the 2023 season — tied for 2nd best in MLB; League Avg: .142.

The Twins are just 8-14 (.364) after a loss as underdogs this season — 5th lowest in MLB; League Avg: .434.

Guardians Keys to the Game vs. the Twins

The Guardians are 67-2 (.971) when leading entering the 7th inning this season — best in MLB; League Avg: .857.

The Guardians are 39-170 (.187) when trailing entering the 7th inning since the 2022 season — 2nd best in MLB; League Avg: .134.

The Guardians are just 3-56 (.051) when trailing entering the 8th inning this season — 3rd lowest in MLB; League Avg: .101.

The Guardians are 29-11 (.725) when they’ve scored in the first inning this season — 4th best in MLB; League Avg: .642.

Twins hitters have 139 extra-base hits out of 334 total hits (42%) when facing the starting pitcher for the 3rd time in a game since last season — best in MLB; League Avg: 37%.

The Twins are batting just .119 when facing the starting pitcher for the 3rd time in a game this month (14 games) — lowest in MLB; League Avg: .252.

Twins hitters are slugging .445 at home this season — 3rd best in MLB; League Avg: .406.

The Twins are batting just .200 in lefty-lefty matchups since last season — lowest in MLB; League Avg: .239.

The Guardians are batting just .293 on the first pitch of at-bats this season — 2nd lowest in MLB; League Avg: .331.

Guardians hitters have put just 34% of balls in play to the left side of the field since last season — tied for lowest in MLB; League Avg: 38%.

The Guardians have barrels in 4% of PA’s since last season (439/11,665) — lowest in MLB; League Avg: 5%.

Guardians hitters had a Hard-Hit Rate of just 33% in the 2023 season — lowest in MLB; League Avg: 40%.

Twins pitchers have walked 832 of 11,596 batters (7%) since last season — 2nd best in MLB; League Avg: 8%.

Twins pitchers have walked 182 of 2,786 batters (7%) when facing the leadoff batter in the inning since last season — 3rd best in MLB; League Avg: 8%.

Twins pitchers have induced opposing hitters to ground into just 66 double plays in 941 opportunities (7%) this season — 2nd lowest in MLB; League Avg: 10%.

Twins pitchers have walked 389 of 5,568 batters (7%) this season — tied for 2nd best in MLB; League Avg: 8%.

Opponents have a groundball batting average of just .204 against Guardians pitchers with runners on base this season — best in MLB; League Avg: .262.

Opponents have a groundball batting average of just .222 against Guardians pitchers this season — best in MLB; League Avg: .249.

The Guardians have allowed 0.87 runs per game (131/151) in late innings this season — best in MLB; League Avg: 1.30.

Guardians pitchers have won 39% of games in which they have allowed their opponent to score in three different innings at home since last season — 2nd highest in MLB; League Avg: 28%.

Guardians vs. Twins Injuries Tonight That May Affect Prop Bets 

  • Cleveland Guardians – No Injuries Reported
  • Minnesota Twins – No Injuries Reported

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.