Giants vs Panthers Prediction, Odds & Best Prop Bets โ€“ NFL, Week 10

Carolina Panthers quarterback Bryce Young passes against the New Orleans Saints during the first half of an NFL football game Monday, Sept. 18, 2023, in Charlotte, N.C.
(Rusty Jones/AP Photo)
  • The Giants are -6 point favorites vs the Panthers
  • Total (Over/Under): 40.5 points
  • Watch this game on NFLN

The New York Giants (2-7-0) visit Allianz Arena to take on the Carolina Panthers (2-7-0) on Nov. 10. Kickoff is scheduled for 9:30am EST in .

The Giants are betting favorites in this matchup, with the spread sitting at -6 (-110).

The Giants vs. Panthers Over/Under is 40.5 total points for the game.

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Giants vs. Panthers Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Giants-6 -11040.5 -105-275
Panthers +6 -11040.5 -115+220

Giants vs. Panthers Prediction

The winning team model predicts the Giants will win this game with 65.2% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Giants vs Panthers Spread Prediction

Based on recent against-the-spread trends, the model predicts the Panthers will cover the spread with 63.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Giants players this playoff game, looking at profitable historical betting trends:

Best Giants Player Prop Bets Today

  • Darius Slayton has hit the Receptions Over in 11 of his last 15 games (+8.80 Units / 56% ROI)
  • Darius Slayton has hit the Receiving Yards Over in 12 of his last 16 games (+7.30 Units / 39% ROI)
  • Devin Singletary has hit the Longest Rush Over in 9 of his last 11 games (+6.75 Units / 54% ROI)
  • Tommy DeVito has hit the Interceptions Under in his last 5 games (+6.00 Units / 120% ROI)
  • Jalin Hyatt has hit the Receiving Yards Under in 7 of his last 9 games (+4.55 Units / 43% ROI)

And here are some top NFL player prop bets for Panthers players for this matchup, looking at profitable historical betting trends:

Best Panthers Player Prop Best Bets Today

  • Bryce Young has hit the Passing Yards Under in 11 of his last 13 games (+8.65 Units / 52% ROI)
  • Bryce Young has hit the TD Passes Under in 9 of his last 13 games (+7.55 Units / 52% ROI)
  • Chuba Hubbard has hit the Rushing Yards Over in 7 of his last 8 games at home (+5.80 Units / 63% ROI)
  • Miles Sanders has hit the Carries Under in 11 of his last 15 games (+5.60 Units / 29% ROI)
  • Adam Thielen has hit the Receptions Under in 9 of his last 12 games (+5.55 Units / 34% ROI)

Rushing Props: Total Rushing Yards for Panthers vs Giants

Player Name Over Under
Daniel Jones (NYG) 27.5 -110 27.5 -120
  • The New York Giants have hit the 2Q Moneyline in 9 of their last 17 games (+7.42 Units / 43% ROI)
  • The New York Giants have scored last in 6 of their last 8 games (+5.65 Units / 71% ROI)
  • The New York Giants have covered the 2Q Spread in 6 of their last 8 away games (+3.90 Units / 43% ROI)
  • The New York Giants have hit the Team Total Over in 6 of their last 9 away games (+2.80 Units / 27% ROI)
  • The New York Giants have scored first in 4 of their last 7 games (+2.20 Units / 31% ROI)
  • The Carolina Panthers have hit the 3Q Game Total Under in 13 of their last 18 games (+7.25 Units / 32% ROI)
  • The Carolina Panthers have hit the 4Q Game Total Under in 13 of their last 18 games (+6.55 Units / 29% ROI)
  • The Carolina Panthers have covered the 3Q Spread in 12 of their last 18 games (+4.70 Units / 20% ROI)
  • The Carolina Panthers have hit the 2Q Game Total Over in 6 of their last 8 games at home (+4.00 Units / 45% ROI)
  • The Carolina Panthers have hit the 1H Game Total Over in 12 of their last 20 games (+3.10 Units / 14% ROI)

Giants Against the Spread (ATS) Record

Against the spread this NFL season, the Giants art 3-6 (-3.5 Units / -35.71% ROI).

  • Giants are 2-7 when betting on the Moneyline for -2.1 Units / -23.08% ROI
  • Giants are 3-6 when betting the Over for -3.65 Units / -36.68% ROI
  • Giants are 6-3 when betting the Under for +2.7 Units / ROI

Panthers Against the Spread (ATS) Record

Against the spread this NFL season, the Panthers are 2-7 (-5.6 Units / -57.44% ROI).

  • Panthers are 2-7 when betting on the Moneyline for -2.1 Units / -23.33% ROI
  • Panthers are 7-2 when betting the Over for +4.8 Units / 48.48% ROI
  • Panthers are 2-7 when betting the Under for -5.7 Units / -57.58% ROI

New York Giants: Keys to the Game vs. the Carolina Panthers

The Giants were 3-6 (.333) when forcing 2 or more turnovers last season — T-2nd-worst in NFL; League Avg: .707.

The Giants are 1-4 (.200) when converting less than 55% of its red zone chances into touchdowns this season — T-6th-worst in NFL; League Avg: .431.

The Giants were 5-10 (.333) when converting less than 50% of third down conversion opportunities last season — T-7th-worst in NFL; League Avg: .430.

The Giants are 5-16 (.238) when allowing an average of more than 5 yards on first down plays since the 2023 season — 3rd-worst in NFL; League Avg: .424.

Carolina Panthers: Keys to the Game vs. the New York Giants

The Panthers were winless (0-4) when sacking the QB 3 or more times last season — worst in NFL; League Avg: .650.

The Panthers are 1-4 (.200) when sacking the QB 3 or more times since the 2023 season — worst in NFL; League Avg: .651.

The Panthers are 2-19 (.095) when the opposing team commits less than 60 yards in penalties since the 2023 season — worst in NFL; League Avg: .494.

The Panthers are 1-5 (.167) when rushing more than 30 times since the 2023 season — worst in NFL; League Avg: .747.

Additional Matchup Notes for New York Giants vs. Carolina Panthers

The Panthers have run successful plays on just 35.0% of pass attempts against a light front this season — 4th-worst in NFL. The Giants have allowed successful plays on just 33.9% of pass attempts with a light front this season — 5th-best in NFL.

The Panthers have averaged just -0.30 epa per play on play action passes since the 2023 season — worst in NFL. The Giants have allowed just -0.07 epa per play on play action passes since the 2023 season — 2nd-best in NFL.

The Panthers have averaged just -0.30 epa per play on play action passes since the 2023 season — worst in NFL. The Giants have allowed just -0.07 epa per play on play action passes since the 2023 season — 2nd-best in NFL.

The Giants have run successful plays on just 33.3% of pass attempts against a stacked front since the 2023 season — worst in NFL. The Panthers have allowed successful plays on just 36.4% of pass attempts with a stacked front since the 2023 season — 2nd-best in NFL.

The Giants have run successful plays on just 33.3% of pass attempts against a stacked front since the 2023 season — worst in NFL. The Panthers have allowed successful plays on just 36.4% of pass attempts with a stacked front since the 2023 season — 2nd-best in NFL.

The Giants have run successful plays on just 33.3% of pass attempts against a stacked front since the 2023 season — worst in NFL. The Panthers have allowed successful plays on just 36.4% of pass attempts with a stacked front since the 2023 season — 2nd-best in NFL.

New York Giants Offense: Important Stats

The Giants averaged -0.26 epa per play against a stacked front last season — worst in NFL; League Avg: 0.01.

The Giants ran successful plays on 26% of pass attempts against a stacked front last season — worst in NFL; League Avg: 50%.

Giants QBs were sacked 85 times last season — most in NFL.

The Giants were sacked on 14% of pass attempts (85/603) last season — worst in NFL; League Avg: 7%.

Carolina Panthers Offense: Important Stats

The Panthers have averaged -0.44 epa per play on play action passes this season — worst in NFL; League Avg: 0.07.

The Panthers have turned the ball over on downs 38 times since the 2023 season — most in NFL.

The Panthers averaged 13.6 drives per TD in the 1st half last season — 2nd-worst Drives Per TD rate in NFL; League Avg: 4.9.

The Panthers turned the ball over on downs 25 times last season — most in NFL.

New York Giants Defense: Important Stats

The Giants defense allowed 6.8 yards per dropback (1,053 yards/156 attempts) when targeted at a depth of 1-5 yards last season — T-worst in NFL; League Avg: 5.5.

The Giants defense blitzed on 25% of plays last season — 2nd-highest in NFL; League Avg: 15%.

The Giants defense have allowed 0.61 epa per play with a stacked front this season — worst in NFL; League Avg: 0.06.

The Giants defense has sacked opposing QBs on 52% of pass attempts (35/68) when they have pressured the QB this season — 2nd-best in NFL; League Avg: 32%.

Carolina Panthers Defense: Important Stats

The Panthers defense has averaged a sack every 28.0 pass attempts (280 Pass Attempts/10 Sacks) this season — 2nd-worst attempts per sack rate in NFL; League Avg: 14.0.

The Panthers defense allowed an average of 2.4 yards after contact per carry (422 carries) to RBs last season — worst in NFL; League Avg: 1.9.

The Panthers defense has allowed successful plays on 59% of rush attempts in the 1st half this season — worst in NFL; League Avg: 43%.

The Panthers defense allowed an average of 2.3 yards after contact per carry (472 carries) last season — worst in NFL; League Avg: 1.8.

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About the Author

Nick Hennion

Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.