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The Padres odds to win the World Series are +2200.
World Series Favorites
The Padres odds to win the NL pennant are +1200.
NL Pennant Favorites
The Padres NL West champion odds are +600
NL West Odds
The Padres odds to make the playoffs are -210. Their odds to miss the playoffs are +175.
The Cleveland Guardians (+145) visit Petco Park to take on the San Diego Padres (-175) on Tuesday, April 1, 2025. First pitch is scheduled for 9:40pm EDT in San Diego, CA. This season, the Guardians a Read More
The Cleveland Guardians (+115) visit Petco Park to take on the San Diego Padres (-135) on Monday, March 31, 2025. First pitch is scheduled for 9:40pm EDT in San Diego, CA. This season, the Guardians a Read More
The Atlanta Braves (+105) visit Petco Park to take on the San Diego Padres (-125) on Sunday, March 30, 2025. First pitch is scheduled for 7:10pm EDT in San Diego, CA. This season, the Braves are 0-3 a Read More
The Atlanta Braves (-140) visit Petco Park to take on the San Diego Padres (+120) on Saturday, March 29, 2025. First pitch is scheduled for 7:15pm EDT in San Diego, CA. This season, the Braves are 0-0 Read More
Find out which MLB teams had the youngest and oldest Opening Day roster for the 2025 season. Read More
The Atlanta Braves (+105) visit Petco Park to take on the San Diego Padres (-125) on Friday, March 28, 2025. First pitch is scheduled for 9:40pm EDT in San Diego, CA, USA. This season, the Braves are Read More
The Atlanta Braves (-130) visit Petco Park to take on the San Diego Padres (+110) on Thursday, March 27, 2025. First pitch is scheduled for 4:10pm EDT in San Diego, CA, USA. This preseason, the Braves Read More
Best MLB teams for 2025. See power rankings for the top MLB teams this season, including the Dodgers, Yankees, Braves, Orioles, and Mets. Read More
Season betting previews and predictions for the Diamondbacks, Dodgers, Giants, Padres, and Rockies ahead of the 2025 MLB season. Read More
Run lines, over/under totals, moneylines, and more odds are available for each Padres game this season.
If you’re in California and interested in odds for other teams, check out:
Will the Padres win the NL West? Will they win the NL pennant? How many RBIs will a certain player hit this season?
For example: If you bet $50 on the Padres (+550) to make the postseason, the bet would settle when San Diego is eliminated or when they clinch a postseason berth.
The run line is baseball’s version of the spread. What’s the final scoring margin of the game?
For example: If you bet $35 on the Padres -1.5 (+120) against the Arizona Diamondbacks, San Diego must win the game by at least two runs.
Alternatively, if you bet $35 on the Padres +1.5 (-150) against the Atlanta Braves, San Diego must lose by one run (or win the game).
Will the Padres win the game?
For example: If you bet $65 on the Padres -200 against the Toronto Blue Jays, San Diego must win the game (in nine innings or extra innings).
How many combined runs will be scored by both teams in the matchup?
For example: If you bet $30 on over 8.5 (-115) in their game against the Cincinnati Reds, the teams must combine for at least nine runs.
Alternatively, if you bet $40 on under 8.5 (-105), the teams must combine for eight or fewer runs.
If the combined run total is the same as the over/under total, the bet is a push.
You can combine bets and other bets — baseball or another sport — into one parlay.
For example: If you bet $15 on a two-leg parlay with the Padres moneyline (-160) vs. the Minnesota Twins and over 7.5 (-105) in the Chicago Cubs-Miami Marlins game, both must hit for the bet to cash.
If one bet is a push, it’s eliminated from the parlay, and odds (and payout) are recalculated without that leg.
