Cardinals vs Brewers Prediction, Odds & Player Prop Bets Today – MLB, Jun 21

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Jun 21, 2022, 12:00 PM
  • The Cardinals (38-31) are -130 favorites vs the Brewers (39-30)
  • Cardinals starting pitcher: Jack Flaherty (0-0), 6.00 ERA
  • Brewers starting pitcher: Alexander González (0-0), 7.71 ERA
  • Watch the game on BSWI

The St. Louis Cardinals (-130) visit American Family Field to take on the Milwaukee Brewers (+110) on Tuesday, June 21, 2022. First pitch is scheduled for 8:10pm EDT in Milwaukee.

The Cardinals are betting favorites in this MLB matchup, with the run line sitting at -1.5 (+120).

The Cardinals vs Brewers Over/Under is 9.5 total runs for the game.

So far this season, the Cardinals are 38-31 against the spread (ATS), while the Brewers are 30-39 ATS.

Cardinals vs. Brewers Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
Cardinals-1.5 +120O 9.5 -120-130
Brewers +1.5 -145U 9.5 +100+110

Cardinals vs Brewers Prediction for Today’s Game

Based on recent trends the model predicts the Cardinals will win Tuesday‘s matchup with 55.0% confidence.

This prediction factors in starting pitchers, recent team and player hitting performances, the last 5 games for both the Cardinals and Brewers and up-to-date player injuries.


Looking for a first bet offer up to $1,000? Bet now on Brewers vs Cardinals and all MLB games with BetMGM


Best Cardinals Player Prop Bets Today

We’ve highlighted some favorite MLB player prop bets for Cardinals players for Tuesday‘s game, looking at profitable historical betting trends:

  • Harrison Bader has hit the Singles Over in 10 of his last 12 away games (+8.80 Units / 73% ROI)
  • Harrison Bader has hit the Hits Over in 10 of his last 12 away games (+7.25 Units / 32% ROI)
  • Paul Goldschmidt has hit the RBIs Under in 8 of his last 9 away games (+6.70 Units / 41% ROI)
  • Tommy Edman has hit the Total Bases Under in 7 of his last 8 away games (+5.75 Units / 46% ROI)
  • Tommy Edman has hit the Hits Under in 7 of his last 9 away games (+4.95 Units / 27% ROI)
  • Best Brewers Player Prop Best Bets Today

    And here are some favorite MLB player prop bets for Brewers players for Tuesday‘s game, looking at profitable historical betting trends:

  • Andrew McCutchen has hit the Runs Under in his last 9 games at home (+9.00 Units / 57% ROI)
  • Rowdy Tellez has hit the Runs Under in his last 9 games at home (+9.00 Units / 49% ROI)
  • Hunter Renfroe has hit the Hits Over in his last 6 games (+6.00 Units / 50% ROI)
  • Hunter Renfroe has hit the Total Bases Over in his last 5 games (+5.75 Units / 103% ROI)
  • Christian Yelich has hit the Hits Over in 9 of his last 13 games (+5.10 Units / 21% ROI)
  • Brewers vs Cardinals Home Run Prop Bets Today

    Over Under
    Andrew McCutchen 0.5 +350 0.5 -650
    Christian Yelich 0.5 +350 0.5 -650
    Hunter Renfroe 0.5 +280 0.5 -450
    Jace Peterson 0.5 +625 0.5 -2000
    Luis Urias 0.5 +425 0.5 -800

    Brewers vs Cardinals Total Hits Prop Bets Today

    Over Under
    Andrew McCutchen 0.5 -200 0.5 +140
    Christian Yelich 0.5 -275 0.5 +180
    Hunter Renfroe 0.5 -190 0.5 +130
    Jace Peterson 0.5 -160 0.5 +115
    Luis Urias 0.5 -160 0.5 +115

    Brewers vs Cardinals RBI Prop Bets Today

    Over Under
    Andrew McCutchen 0.5 +155 0.5 -225
    Christian Yelich 0.5 +155 0.5 -225
    Hunter Renfroe 0.5 +145 0.5 -200
    Jace Peterson 0.5 +240 0.5 -375
    Luis Urias 0.5 +195 0.5 -300

    Brewers vs Cardinals Strikeout Prop Bets Today

    Over Under
    Jack Flaherty 4.5 -115 4.5 -120
  • The St. Louis Cardinals have hit the Game Total Over in 30 of their last 53 games (+6.50 Units / 11% ROI)
  • The St. Louis Cardinals have hit the 1st Five Innings (F5) Total Under in 14 of their last 22 games (+6.25 Units / 26% ROI)
  • The St. Louis Cardinals have covered the Run Line in 36 of their last 64 games (+6.15 Units / 7% ROI)
  • The St. Louis Cardinals have hit the Moneyline in 21 of their last 37 games (+3.70 Units / 8% ROI)
  • The St. Louis Cardinals have covered the 1st Five Innings (F5) Run Line in 16 of their last 31 games (+0.10 Units / 0% ROI)
  • The Milwaukee Brewers have hit the 1st Five Innings (F5) Total Over in 28 of their last 49 games (+7.55 Units / 14% ROI)
  • The Milwaukee Brewers have covered the Run Line in 5 of their last 6 games (+4.80 Units / 62% ROI)
  • The Milwaukee Brewers have hit the Game Total Over in 28 of their last 49 games (+4.65 Units / 8% ROI)
  • The Milwaukee Brewers have covered the 1st Five Innings (F5) Run Line in 6 of their last 8 games (+4.20 Units / 45% ROI)
  • The Milwaukee Brewers have hit the Moneyline in 5 of their last 6 games (+4.00 Units / 53% ROI)
  • Cardinals Against the Spread (ATS) Record

    Against the spread this MLB season, the Cardinals have gone 38-31 against the Run Line (+4.8 Units / 5.37% ROI).

    • 38-31 when betting on the Moneyline for +1.25 Units / 1.39% ROI
    • 36-30 when betting on the total runs Over for +2.75 Units / 3.6% ROI
    • 30-36 when betting on the total runs Under for -9.3 Units / -12.26% ROI

    Brewers Against the Spread (ATS) Record

    Against the spread this MLB season, the Cardinals have gone 30-39 against the Run Line (-10 Units / -12.26% ROI).

    • 39-30 when betting on the Moneyline for -3.55 Units / -3.34% ROI
    • 33-33 when betting on the total runs Over for -3.15 Units / -4.08% ROI
    • 33-33 when betting on the total runs Under for -2.15 Units / -2.86% ROI

    Jack Flaherty has limited playing time.

    Alexander González: Brewers Starting Pitcher Stats & Trends

    Chi Chi Gonzalez has not allowed a walk in any of his last three starts — the longest active streak is 6.

    Cardinals Keys to the Game vs. the Brewers

    The Cardinals are 21-13 (.618) at home this season — 5th best in MLB; League Avg: .514.

    The Cardinals are 32-0 (1.000) when leading entering the 8th inning this season — tied for best in MLB; League Avg: .927.

    The Cardinals are just 1-29 (.033) when trailing entering the 8th inning this season — tied for 7th lowest in MLB; League Avg: .073.

    The Cardinals are 32-10 (.762) when allowing 4 or fewer runs this season — 10th best in MLB; League Avg: .705.

    Brewers Keys to the Game vs. the Cardinals

    The Brewers are 23-18 (.561) on the road this season — 6th best in MLB; League Avg: .486.

    The Brewers are 3-23 (.115) when trailing entering the 8th inning this season — 6th best in MLB; League Avg: .073.

    The Brewers are 16-5 (.762) when scoring in the first inning this season — 7th best in MLB; League Avg: .675.

    The Brewers are just 3-13 (.188) when allowing 10 or more hits this season — 5th lowest in MLB; League Avg: .280.

    Cardinals hitters have 175 extra-base hits out of 408 total hits (43%) against LHP since the start of last season — 2nd best in MLB; League Avg: 35%.

    Cardinals hitters are slugging .460 against LHP since the start of last season — 2nd best in MLB; League Avg: .409.

    Cardinals hitters have 202 extra-base hits out of 480 total hits (42%) against LHP since the start of 2020 — 2nd best in MLB; League Avg: 36%.

    Cardinals hitters have an OBP of .342 (525 PA’s) against LHP this season — 4th best in MLB; League Avg: .317.

    The Brewers are batting just .222 against LHP this season — 3rd lowest in MLB; League Avg: .244.

    Brewers hitters are averaging 4.08 pitches per plate appearance this season — highest in MLB; League Avg: 3.90.

    Brewers hitters have chased 25% of pitches out of the zone against LHP since the start of last season — lowest in MLB; League Avg: 28%.

    The Brewers are batting just .224 at home since the start of 2020 — 3rd lowest in MLB; League Avg: .247.

    Cardinals pitchers have a strikeout rate of just 11% with runners in scoring position over the last 14 days (13 games) — lowest in MLB; League Avg: 21%.

    Cardinals pitchers have a strikeout rate of just 39% with two-strikes since the start of last season — 3rd lowest in MLB; League Avg: 43%.

    Cardinals pitchers have walked 60 of 612 batters (10%) when facing the leadoff batter in the inning this season — 2nd highest in MLB; League Avg: 8%.

    Opponents have a miss rate of just 23% against Cardinals pitchers since the start of last season — 2nd lowest in MLB; League Avg: 26%.

    Brewers pitchers have a strikeout rate of 30% in close and late situations since the start of last season — best in MLB; League Avg: 25%.

    Opponents have a miss rate of 28% against Brewers pitchers this season — tied for 3rd best in MLB; League Avg: 26%.

    Opponents have a groundball rate of 46% against Brewers pitchers since the start of last season — 3rd highest in MLB; League Avg: 44%.

    Brewers pitchers have allowed opponents to score in three different innings in 34% of their games since the start of last season — lowest in MLB; League Avg: 45%.

    Brewers vs. Cardinals Injuries Tonight That May Affect Prop Bets 

  • Luis Perdomo (Brewers): Elbow, D15
  • Alex J Jackson (Brewers): Finger, D10
  • Trevor Gott (Brewers): Groin, D15
  • Jake O. Cousins (Brewers): Elbow, D60
  • Kolten Wong (Brewers): Calf, D10
  • Aaron Ashby (Brewers): Forearm, D15
  • Brandon Woodruff (Brewers): Ankle, D15
  • Jandel Gustave (Brewers): Hamstring, D15
  • Justin Topa (Brewers): Elbow, D60
  • Freddy Peralta (Brewers): Lat, D60
  • Michael Brosseau (Brewers): Ankle, D10
  • Alexander Reyes (Cardinals): Shoulder, D60
  • Tyler O’Neill (Cardinals): Hamstring, D10
  • McKenzie Dickerson (Cardinals): Calf, D10
  • Jordan Hicks (Cardinals): Forearm, D15
  • Steven Matz (Cardinals): Shoulder, D15
  • Yadier Molina (Cardinals): Knee, D10

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    About the Author

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    Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

    Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.