- The 49ers are a 6.5-point home favorite against the Seahawks.
- The 49ers have won each of their last 10 games in November.
- My 49ers vs. Seahawks prediction is for the Seahawks to cover the spread.
Off a narrow road win against the Buccaneers, the 49ers return home for a divisional matchup with the Seahawks.
San Francisco moved to 5-4 on Sunday with a 23-20 road win against the Buccaneers. With a win over Seattle in Week 11, San Francisco would move into a tie for the NFC West lead.
Seattle, which held a Week 10 bye, has lost two straight games. In the last meeting against the 49ers, the Seahawks fell 36-24 on Thursday Night Football.
Bet on 49ers vs. Seahawks and other NFL matchups with up-to-date NFL odds.
NFL Week 11 Odds: 49ers vs. Seahawks
49ers vs. Seahawks Prediction
Based on Seattle’s strong running game and Geno Smith’s strong record as a favorite, my 49ers vs. Seahawks prediction is the Seahawks Spread (+6.5, -110).
I would prefer this a lot more at +7, but San Francisco has done little to warrant this big a spread against a team coming off a bye week.
While Christian McCaffrey’s return should help San Francisco’s offense against a bad Seattle defense, Seattle can move the ball on the Niners.
In the previous meeting, the Seahawks amassed 358 yards of offense, including 312 yards through the air.
Amidst that trend, this is also a great buy-low spot on Seattle’s offense.
Entering Week 11, Seattle ranks 17th in offensive DVOA. However, they’ve faced the 12th-hardest schedule of opposing defenses.
Meanwhile, the 49ers rank fifth in total defensive DVOA after facing the 14th-easiest schedule of opposing offenses.
With an extra week to prepare, one would think Seattle can keep up offensively with the 49ers.
Seahawks quarterback Geno Smith has also excelled as a big underdog. In his career, Smith is 15-9-2 ATS as a dog of +4.5 or higher.
Seattle also matches a historically profitable betting system in Week 11.
Road divisional dogs in game seven onward that lost the last meeting by at least a touchdown are 44-17 ATS (72%) when priced between +4 and +6.5.
When those dogs have two weeks between games: 4-0 ATS.
Back the Seahawks to cover the spread on Sunday in Santa Clara.
49ers vs. Seahawks: NFL Public Betting Trends
| Bets% (Spread) | Money% (Spread) | Bets% (ML) | Money% (ML) | |
|---|---|---|---|---|
| Seahawks | 31% | 34% | 47% | 64% |
| 49ers | 69% | 66% | 53% | 36% |
