Cardinals vs Seahawks Prediction, Odds & Best Prop Bets – NFL, Week 6

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Seattle Seahawks running back Kenneth Walker III (9) runs
(AP Photo/Ashley Landis)
BetMGM Betting @BETMGM Oct 16, 2022, 9:05 AM
  • The Cardinals (2-3) are -2.5 point favorites vs the Seahawks (2-3)
  • Total (Over/Under): 50.5 points
  • Watch the game on FOX

The Arizona Cardinals (2-3) visit Lumen Field to take on the Seattle Seahawks (2-3) on Oct. 16. Kickoff is scheduled for 4:05pm EDT in Seattle.

The Cardinals are betting favorites in Week 6, with the spread sitting at -2.5 (-110).

The Cardinals vs. Seahawks Over/Under is 50.5 total points for the game.

Bet now on Seahawks vs Cardinals & all NFL games with BetMGM

Cardinals vs. Seahawks Odds, Spread, Over/Under Week 6

SpreadTotal (O/U)Moneyline
Cardinals-2.5 -11050.5 -110-145
Seahawks +2.5 -11050.5 -110+120

Cardinals vs. Seahawks Prediction for Week 6

Based on recent trends, the winning team model predicts the Cardinals will win this Week 6 game with 67.5% confidence.

Cardinals vs Seahawks Spread Prediction for Week 6

Based on recent against-the-spread trends, the model predicts the Cardinals will cover the spread this Week 6 with 60.0% confidence.

Both predictions factor in up-to-date player injuries for both the Cardinals and Seahawks, plus offensive & defensive matchups, recent games and key player performances this season.


Best Cardinals Player Prop Bets Today

We’ve highlighted some favorite NFL player prop bets for Cardinals players for Week 6, looking at profitable historical betting trends:

  • Marquise Brown has hit the Receptions Over in 12 of his last 16 games (+8.75 Units / 51% ROI)
  • Darrel Williams has hit the Receptions Over in 8 of his last 10 games (+7.10 Units / 61% ROI)
  • Zach Ertz has hit the Receptions Over in 11 of his last 16 games (+5.70 Units / 31% ROI)
  • Darrel Williams has hit the Rushing Yards Under in 8 of his last 10 games (+5.40 Units / 41% ROI)
  • Rondale Moore has hit the Receiving Yards Under in 8 of his last 11 games (+4.15 Units / 29% ROI)
  • Best Seahawks Player Prop Best Bets Today

    And here are some top NFL player prop bets for Seahawks players for Week 6, looking at profitable historical betting trends:

  • Rashaad Penny has hit the Receiving Yards Under in his last 6 games (+6.00 Units / 82% ROI)
  • Geno Smith has hit the Pass Attempts Under in 7 of his last 8 games (+5.65 Units / 50% ROI)
  • Geno Smith has hit the Interceptions Under in 6 of his last 8 games (+4.80 Units / 56% ROI)
  • Tyler Lockett has hit the Receptions Under in 10 of his last 15 games (+4.25 Units / 23% ROI)
  • Geno Smith has hit the Completions Over in 6 of his last 8 games (+3.80 Units / 43% ROI)
  • First Touchdown Scorer Bet for Seahawks vs Cardinals

    Player Name 1st TD Odds
    Eno Benjamin +550
    Kenneth Walker +600
    Marquise Brown +750
    Kyler Murray +800
    Zach Ertz +900

    Anytime Touchdown Scorer Bet for Seahawks vs Cardinals

    Player Name Anytime TD Odds
    Eno Benjamin -190
    Kenneth Walker -165
    Marquise Brown -110
    Kyler Murray -105
    Tyler Lockett +105

    Receiving Props: Total Receiving Yards for Seahawks vs Cardinals

    Player Name Over Under
    DK Metcalf 69.5 -115 69.5 -115
    Zach Ertz 48.5 -115 48.5 -115
    Fant 25.5 -120 25.5 -115
    Tyler Lockett 67.5 -120 67.5 -110
    Rondale Moore 44.5 -110 44.5 -120

    Rushing Props: Total Rushing Yards for Seahawks vs Cardinals

    Player Name Over Under
    Kenneth Walker III 61.5 -120 61.5 -115
    Kyler Murray 26.5 -110 26.5 -120
    Geno Smith 12.5 -120 12.5 -110
    Rondale Moore 3.5 -110 3.5 -120
    Eno Benjamin 60.5 -115 60.5 -115
  • The Arizona Cardinals have hit the 2H Game Total Over in 11 of their last 16 games (+6.40 Units / 36% ROI)
  • The Arizona Cardinals have hit the 4Q Moneyline in their last 5 games (+5.80 Units / 114% ROI)
  • The Arizona Cardinals have hit the 1H Game Total Under in their last 5 away games (+5.00 Units / 94% ROI)
  • The Arizona Cardinals have hit the 1Q Game Total Under in their last 5 away games (+5.00 Units / 88% ROI)
  • The Arizona Cardinals have covered the 4Q Spread in their last 5 games (+5.00 Units / 80% ROI)
  • The Seattle Seahawks have hit the 1H Moneyline in 8 of their last 10 games (+9.50 Units / 62% ROI)
  • The Seattle Seahawks have hit the 1H Game Total Over in 9 of their last 11 games (+7.85 Units / 66% ROI)
  • The Seattle Seahawks have covered the 1H Spread in 8 of their last 9 games (+6.80 Units / 69% ROI)
  • The Seattle Seahawks have covered the 1Q Spread in 12 of their last 17 games (+6.35 Units / 33% ROI)
  • The Seattle Seahawks have hit the 2Q Moneyline in 7 of their last 11 games (+6.15 Units / 43% ROI)
  • Cardinals Against the Spread (ATS) Record

    Against the spread this NFL season, the Cardinals have gone 3-2 (+0.75 Units / 13.51% ROI).

    • Cardinals are 2-3 when betting on the Moneyline for +0 Units / 0% ROI
    • Cardinals are 2-3 when betting the Over for -1.3 Units / -23.64% ROI
    • Cardinals are 3-2 when betting the Under for +0.8 Units / ROI

    Seahawks Against the Spread (ATS) Record

    Against the spread this NFL season, the Seahawks have gone 2-3 (-1.3 Units / -23.64% ROI).

    • Seahawks are 2-3 when betting on the Moneyline for +0.75 Units / 14.56% ROI
    • Seahawks are 3-2 when betting the Over for +0.75 Units / 13.51% ROI
    • Seahawks are 2-3 when betting the Under for -1.3 Units / -23.85% ROI

    Arizona Cardinals: Keys to the Game vs. the Seattle Seahawks

    The Cardinals are 11-3 (.786) when possessing the ball longer than their opponent since the 2021 season — eighth-best in NFL. The Seahawks has allowed an average time of possession of 34 min and 14 s since the 2021 season — second-highest in NFL.

    The Cardinals are 9-6 (.600) when passing for 250 or more yards since the 2021 season — tied for 10th-best in NFL. The Seahawks have allowed 264.2 passing yards per game since the 2021 season — second-worst in NFL.

    The Cardinals are winless (0-3) when the opposing team commits less than 60 yards in penalties this season — tied for worst in NFL; League Avg: .471.

    The Cardinals are 11-3 (.786) when possessing the ball longer than their opponent since the 2021 season — 8th-best in NFL; League Avg: .655.

    Seattle Seahawks: Keys to the Game vs. the Arizona Cardinals

    The Seahawks are 2-8 (.200) when converting less than 55% of its red zone chances into touchdowns since the 2021 season — 2nd-worst in NFL; League Avg: .451.

    The Seahawks are 2-8 (.200) when within 7 points at the two minute warning since the 2021 season — tied for 3rd-worst in NFL; League Avg: .493.

    The Seahawks are 3-8 (.273) when making less than 3 explosive runs in a game since the 2021 season — 8th-worst in NFL; League Avg: .452.

    The Seahawks are 1-6 (.143) when allowing more than 3 explosive runs since the 2021 season — tied for 4th-worst in NFL; League Avg: .415.

    Additional Matchup Notes for Arizona Cardinals vs. Seattle Seahawks

    Seahawks TEs have 71.4 receiving yards per game this season — fifth-best in NFL. The Cardinals have allowed an average of87.2 receiving yards per game to TEs this season — worst in NFL.

    Seahawks RBs have averaged 2.4 yards after contact per carry since the 2021 season — tied for second-best in NFL. The Cardinals have allowed 2.1 yards after contact per carry since the 2021 season — tied for second-worst in NFL.

    The Seahawks have scored on 44.7% of their drives this season — fourth-best in NFL. The Cardinals defense has allowed scores on 45.8% of opponent drives this season — third-worst in NFL.

    The Cardinals have been successful on 46.8% of plays they have run since the 2021 season — fifth-best in NFL. Seahawks have allowed their opponents to be successful on 45.8% of plays since the 2021 season — fifth-worst in NFL.

    The Cardinals have scored on 57.1% of their drives in the second half this season — best in NFL. The Seahawks defense has allowed scores on 44% of opponent drives in the second half this season — fifth-worst in NFL.

    The Cardinals have scored on 64.3% of their drives in the fourth quarter this season — best in NFL. The Seahawks defense has allowed scores on 50% of opponent drives in the 4th quarter this season — fourth-worst in NFL.

    Arizona Cardinals Offense: Important Stats for Week 6

    The Cardinals ran no plays in their opponent’s territory in the 3rd quarter in Week 5 — worst in NFL; League Avg: 46%.

    The Cardinals have scored on 64% of their drives in the 4th quarter this season — best in NFL; League Avg: 30%.

    The Cardinals converted first downs on 36 of 102 plays (35%) on 3rd and long last season — best in NFL; League Avg: 25%.

    The Cardinals have run successful plays on 61% of rush attempts in the 2nd half this season — best in NFL; League Avg: 44%.

    Seattle Seahawks Offense: Important Stats for Week 6

    The Seahawks have 8 TDs that were 20+ yards this season — most in NFL.

    The Seahawks have run successful plays on 72% of pass attempts in the 1st quarter this season — best in NFL; League Avg: 47%.

    The Seahawks had 17 TDs that were 20+ yards last season — tied for 2nd-most in NFL.

    The Seahawks have scored on 70% of their drives in the 1st quarter this season — best in NFL; League Avg: 30%.

    Arizona Cardinals Defense: Important Stats for Week 6

    The Cardinals defense has allowed a passer rating of 130.4 when they have pressured the QB (34 Pass Attempts) this season — worst in NFL; League Avg: 52.9.

    The Cardinals defense has blitzed on 50% of plays on 3rd and short this season — highest in NFL; League Avg: 13%.

    The Cardinals defense has blitzed on 40% of plays in the red zone this season — highest in NFL; League Avg: 13%.

    The Cardinals defense has allowed a passer rating of 95.0 when they have pressured the QB (136 Pass Attempts) since the 2021 season — worst in NFL; League Avg: 57.1.

    Seattle Seahawks Defense: Important Stats for Week 6

    The Seahawks defense have forced three and outs on 6% of opponent drives this season — 2nd-worst in NFL; League Avg: 20%.

    The Seahawks defense has allowed 33.2 Points per Game (166/5) this season — worst in NFL; League Avg: 21.7.

    The Seahawks defense has allowed scores on 58% of opponent drives in the 1st quarter this season — tied for worst in NFL; League Avg: 30%.

    The Seahawks defense has allowed 30.8 points per game to opposing offenses (154 points / 5 games) this season — worst in NFL; League Avg: 20.7.

    Looking to place a bet on this game with a risk-free bet up to $1,000? Bet now on Seahawks vs Cardinals and all NFL games with BetMGM

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    Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

    Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.