Commanders vs Cardinals Prediction, Odds & Best Prop Bets โ€“ NFL, Week 4

Arizona Cardinals quarterback Kyler Murray throws a pass against the Philadelphia Eagles during the second half of an NFL football game, Sunday, Dec. 31, 2023, in Philadelphia. (AP Photo/Derik Hamilton)
(AP Photo/Derik Hamilton)
  • The Cardinals are -3.5 point favorites vs the Commanders
  • Total (Over/Under): 50.5 points
  • Watch this game on FOX

The Washington Commanders (2-1-0) visit State Farm Stadium to take on the Arizona Cardinals (1-2-0) on Sep. 29. Kickoff is scheduled for 4:05pm EDT in Glendale, AZ.

The Cardinals are betting favorites in this matchup, with the spread sitting at -3.5 (-105).

The Commanders vs. Cardinals Over/Under is 49.5 total points for the game.

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Commanders vs. Cardinals Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Commanders+3.5 -11549.5 -110+145
Cardinals -3.5 -10549.5 -110-175

Commanders vs. Cardinals Prediction

The winning team model predicts the Cardinals will win this game with 71.0% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Commanders vs Cardinals Spread Prediction

Based on recent against-the-spread trends, the model predicts the Cardinals will cover the spread with 69.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Commanders players this playoff game, looking at profitable historical betting trends:

Best Commanders Player Prop Bets Today

  • Austin Ekeler has hit the Longest Rush Under in his last 6 games (+6.00 Units / 82% ROI)
  • Terry McLaurin has hit the Longest Reception Over in 7 of his last 8 away games (+5.80 Units / 61% ROI)
  • Austin Ekeler has hit the Receptions Under in 7 of his last 8 away games (+5.30 Units / 48% ROI)
  • Brian Robinson has hit the Longest Rush Over in his last 5 games (+5.00 Units / 85% ROI)
  • Noah Brown has hit the Receptions Over in 4 of his last 5 away games (+3.70 Units / 68% ROI)

And here are some top NFL player prop bets for Cardinals players for this matchup, looking at profitable historical betting trends:

Best Cardinals Player Prop Best Bets Today

  • James Conner has hit the Receiving Yards Under in 10 of his last 13 games (+6.35 Units / 38% ROI)
  • James Conner has hit the Longest Reception Under in 7 of his last 8 games (+5.75 Units / 58% ROI)
  • James Conner has hit the Longest Rush Over in his last 5 games (+5.00 Units / 85% ROI)
  • Chris Moore has hit the Receiving Yards Over in 6 of his last 7 games (+4.85 Units / 58% ROI)
  • Kyler Murray has hit the Rushing Yards Over in 8 of his last 11 games (+4.80 Units / 40% ROI)

Receiving Props: Total Receiving Yards for Cardinals vs Commanders

Player Name Over Under
Terry McLaurin (WAS) 56.5 -115 56.5 -115
Marvin Harrison Jr. (ARI) 66.5 -140 66.5 +105
  • The Washington Commanders have covered the 3Q Spread in 12 of their last 17 games (+6.95 Units / 34% ROI)
  • The Washington Commanders have hit the 2Q Game Total Over in 12 of their last 17 games (+6.70 Units / 36% ROI)
  • The Washington Commanders have hit the 1H Game Total Over in 13 of their last 20 games (+6.20 Units / 28% ROI)
  • The Washington Commanders have hit the 1Q Game Total Over in 13 of their last 20 games (+4.90 Units / 21% ROI)
  • The Washington Commanders have hit the Team Total Over in 7 of their last 10 away games (+4.10 Units / 37% ROI)
  • The Arizona Cardinals have hit the 2H Moneyline in 6 of their last 8 games (+7.10 Units / 89% ROI)
  • The Arizona Cardinals have hit the 2Q Game Total Over in 11 of their last 17 games (+4.55 Units / 23% ROI)
  • The Arizona Cardinals have scored last in 4 of their last 5 games at home (+3.80 Units / 73% ROI)
  • The Arizona Cardinals have covered the 2H Spread in 6 of their last 8 games (+3.70 Units / 42% ROI)
  • The Arizona Cardinals have hit the 1H Game Total Over in 12 of their last 20 games (+3.00 Units / 13% ROI)

Commanders Against the Spread (ATS) Record

Against the spread this NFL season, the Commanders art 2-1 (+0.9 Units / 26.47% ROI).

  • Commanders are 2-1 when betting on the Moneyline for +2.8 Units / 86.15% ROI
  • Commanders are 2-1 when betting the Over for +0.9 Units / 27.27% ROI
  • Commanders are 1-2 when betting the Under for -1.2 Units / ROI

Cardinals Against the Spread (ATS) Record

Against the spread this NFL season, the Cardinals are 2-1 (+0.8 Units / 23.53% ROI).

  • Cardinals are 1-2 when betting on the Moneyline for -1 Units / -32.26% ROI
  • Cardinals are 2-1 when betting the Over for +0.9 Units / 27.27% ROI
  • Cardinals are 1-2 when betting the Under for -1.2 Units / -36.36% ROI

Washington Commanders: Keys to the Game vs. the Arizona Cardinals

The Commanders were 1-8 (.111) when playing in cold weather last season — 2nd-worst in NFL; League Avg: .500.

The Commanders are 1-8 (.111) when playing in cold weather since the 2022 season — 2nd-worst in NFL; League Avg: .500.

The Commanders are 1-9 (.100) after a road win since the 2022 season — worst in NFL; League Avg: .459.

The Commanders are 2-7 (.222) at home since the 2022 season — T-2nd-worst in NFL; League Avg: .548.

Arizona Cardinals: Keys to the Game vs. the Washington Commanders

The Cardinals were winless (0-3) when forcing 2 or more turnovers last season — worst in NFL; League Avg: .707.

The Cardinals are winless (0-3) when forcing 2 or more turnovers since the 2022 season — worst in NFL; League Avg: .710.

The Cardinals were winless (0-10) when scoring less than 22 points last season — T-worst in NFL; League Avg: .253.

The Cardinals were 1-6 (.143) when sacking the QB 3 or more times last season — 2nd-worst in NFL; League Avg: .650.

Additional Matchup Notes for Washington Commanders vs. Arizona Cardinals

The Cardinals have a third down conversion rate of 45.5% this season — 4th-best in NFL. The Commanders defense has allowed a third down conversion rate of 61.3% this season — worst in NFL.

The Cardinals have run successful plays on just 39.0% of pass attempts against a stacked front since the 2023 season — 3rd-worst in NFL. The Commanders have allowed successful plays on just 32.4% of pass attempts with a stacked front since the 2023 season — 2nd-best in NFL.

The Cardinals have scored on 69.2% of their drives in the first half this season — 3rd-best in NFL. The Commanders defense has allowed scores on 81.8% of opponent drives in the first half this season — worst in NFL.

The Commanders have run successful plays on 85.7% of pass attempts on play action passes this season — best in NFL. The Cardinals have allowed successful plays on 70.0% of pass attempts on play action passes this season — 2nd-worst in NFL.

The Commanders have run successful plays on 55.6% of pass attempts on their opponent’s side of the field this season — 4th-best in NFL. The Cardinals have allowed successful plays on 63.2% of pass attempts on their own side of the field this season — 3rd-worst in NFL.

The Commanders have run successful plays on 62.3% of pass attempts against a base front this season — best in NFL. The Cardinals have allowed successful plays on 54.2% of pass attempts with a base front this season — 4th-worst in NFL.

Washington Commanders Offense: Important Stats

The Commanders have run successful plays on 86% of pass attempts on play action passes this season — best in NFL; League Avg: 50%.

The Commanders have rushed for 6 TDs this season — T-most in NFL.

The Commanders have run 66% of their plays in their opponent’s territory in the 2nd half this season — best in NFL; League Avg: 48%.

The Commanders have scored on 64% of their drives this season — best in NFL; League Avg: 38%.

Arizona Cardinals Offense: Important Stats

The Cardinals have rushed for 20+ yards 29 times since the 2022 season — most in NFL.

The Cardinals have averaged 0.72 epa per play against a light front this season — best in NFL; League Avg: -0.05.

The Cardinals had 23 rushes of 20+ yards last season — most in NFL.

The Cardinals have rushed for 20+ yards 6 times this season — 2nd-most in NFL.

Washington Commanders Defense: Important Stats

The Commanders defense has allowed 48 TD passes since the 2022 season — most in NFL.

The Commanders defense allowed 21 TDs that were 20+ yards last season — most in NFL.

The Commanders defense allowed 39 TD passes last season — most in NFL.

The Commanders defense have allowed 0.18 epa per play with a base rush since the 2022 season — worst in NFL; League Avg: -0.02.

Arizona Cardinals Defense: Important Stats

19% of the plays ran against the Cardinals were in the red zone last season — worst in NFL; League Avg: 14%.

18% of the plays run against the Cardinals have been in the red zone since the 2022 season — worst in NFL; League Avg: 14%.

The Cardinals defense has allowed successful plays on 36% of rush attempts with a stacked front since the 2022 season — best in NFL; League Avg: 44%.

The Cardinals defense has allowed successful plays on 74% of pass attempts with a stacked front since the 2022 season — worst in NFL; League Avg: 50%.

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Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.

Our BetMGM editors and authors are sports experts with a wealth of knowledge of the sports industry at all levels. Their coverage includes sports news, previews and predictions, fun facts, and betting.