- The 49ers are -3.5 point favorites vs the Cowboys
- Total (Over/Under): 45 points
- Watch Sunday Night Football on NBC
The Dallas Cowboys (3-1) visit Levi’s Stadium to take on the San Francisco 49ers (4-0) on Oct. 8. Kickoff is scheduled for 8:20pm EDT in Santa Clara.
The 49ers are betting favorites in this Week 5 matchup, with the spread sitting at -3.5 (-110).
The Cowboys vs. 49ers Over/Under is 45 total points for the game.
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Cowboys vs. 49ers Odds, Spread, Over/Under
| Spread | Total (O/U) | Moneyline | |
| Cowboys | +3.5 -110 | 45 -110 | +150 |
| 49ers | -3.5 -110 | 45 -110 | -185 |
Cowboys vs. 49ers Prediction
Based on recent trends, the winning team model predicts the 49ers will win this Week 5 game with 69.2% confidence.
Cowboys vs 49ers Spread Prediction
Based on recent against-the-spread trends, the model predicts the 49ers will cover the spread with 60.0% confidence.
Both predictions factor in up-to-date player injuries for both the Cowboys and 49ers, plus offensive & defensive matchups, recent games and key player performances this season.
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Best Cowboys Player Prop Bets Today
We’ve highlighted some favorite NFL player prop bets for Cowboys players this Week 5 game, looking at profitable historical betting trends:
- Dak Prescott has hit the Interceptions Over in 10 of his last 13 games (+7.65 Units / 51% ROI)
- Michael Gallup has hit the Longest Reception Under in 11 of his last 14 games (+7.30 Units / 40% ROI)
- Tony Pollard has hit the Longest Reception Under in 8 of his last 9 away games (+6.85 Units / 63% ROI)
- Dak Prescott has hit the TD Passes Over in 9 of his last 11 games (+6.35 Units / 44% ROI)
- Dak Prescott has hit the Rushing Yards Over in his last 6 games (+6.10 Units / 90% ROI)
Best 49ers Player Prop Best Bets Today
And here are some top NFL player prop bets for 49ers players for this matchup, looking at profitable historical betting trends:
- George Kittle has hit the Longest Reception Over in 13 of his last 16 games (+9.55 Units / 51% ROI)
- Jauan Jennings has hit the Receiving Yards Over in 11 of his last 14 games (+7.70 Units / 49% ROI)
- Christian McCaffrey has hit the Carries Under in 8 of his last 9 games (+6.95 Units / 57% ROI)
- Christian McCaffrey has hit the Longest Rush Over in 12 of his last 17 games (+6.10 Units / 32% ROI)
- Deebo Samuel has hit the Longest Reception Under in 7 of his last 8 games (+5.40 Units / 51% ROI)
Cowboys Best Bets:
- The Dallas Cowboys have hit the 1H Game Total Over in 16 of their last 22 games (+9.55 Units / 40% ROI)
- The Dallas Cowboys have hit the 2Q Game Total Over in 13 of their last 19 games (+5.90 Units / 26% ROI)
- The Dallas Cowboys have hit the Team Total Over in 14 of their last 22 games (+5.80 Units / 22% ROI)
- The Dallas Cowboys have hit the 2H Moneyline in 13 of their last 19 games (+4.75 Units / 13% ROI)
- The Dallas Cowboys have covered the 3Q Spread in 12 of their last 19 games (+4.65 Units / 22% ROI)
49ers Best Bets:
- The San Francisco 49ers have hit the 4Q Moneyline in 14 of their last 21 games (+10.45 Units / 29% ROI)
- The San Francisco 49ers have hit the 2H Moneyline in 16 of their last 21 games (+9.85 Units / 23% ROI)
- The San Francisco 49ers have covered the 2H Spread in 15 of their last 21 games (+9.70 Units / 42% ROI)
- The San Francisco 49ers have hit the 2Q Game Total Over in 15 of their last 21 games (+8.25 Units / 35% ROI)
- The San Francisco 49ers have covered the 4Q Spread in 14 of their last 21 games (+6.10 Units / 26% ROI)
Cowboys Against the Spread (ATS) Record
Against the spread this NFL season, the Cowboys went 3-1 (+1.9 Units / 41.76% ROI).
- Cowboys are 3-1 when betting on the Moneyline for -3.2 Units / -21.62% ROI
- Cowboys are 2-2 when betting the Over for -0.2 Units / -4.55% ROI
- Cowboys are 2-2 when betting the Under for -0.2 Units / ROI
49ers Against the Spread (ATS) Record
Against the spread this NFL season, the 49ers went 3-0 (+3 Units / 68.18% ROI).
- 49ers are 4-0 when betting on the Moneyline for +4 Units / 19.75% ROI
- 49ers are 2-2 when betting the Over for -0.2 Units / -4.55% ROI
- 49ers are 2-2 when betting the Under for -0.2 Units / -4.55% ROI
Dallas Cowboys: Keys to the Game vs. the San Francisco 49ers
The Cowboys are 9-2 (.818) vs top 10 run offenses since the 2021 season — best in NFL; League Avg: .433.
The Cowboys are undefeated (4-0) after a home loss since the 2021 season — tied for best in NFL; League Avg: .465.
The Cowboys are 2-1 (.667) after a win as underdogs since the 2022 season — tied for best in NFL; League Avg: .328.
The Cowboys are 9-2 (.818) vs top 10 run defenses since the 2021 season — best in NFL; League Avg: .422.
San Francisco 49ers: Keys to the Game vs. the Dallas Cowboys
The 49ers are undefeated (4-0) this season — tied for best in NFL; League Avg: .500.
The 49ers are undefeated (15-0) when the opposing team converts less than 55% of its red zone chances into touchdowns since the 2021 season — best in NFL; League Avg: .555.
The 49ers are 10-1 (.909) vs bottom 10 run offenses since the 2021 season — best in NFL; League Avg: .551.
The 49ers are undefeated (21-0) when not throwing an interception since the 2021 season — best in NFL; League Avg: .631.
Additional Matchup Notes for Dallas Cowboys vs. San Francisco 49ers
49ers WRs have averaged 5.1 yards after the catch this season — fourth-best in NFL. The Cowboys have allowed 6.6 yards after catch per reception to WRs this season — worst in NFL.
49ers WRs have gained 711 yards on 44 receptions (16.2 YPR) this season — second-best in NFL. The Cowboys have allowed 15.6 Yards Per Reception to WRs this season — second-worst in NFL.
The 49ers are averaging 7.3 yards per carry on rushes to the left side of the field this season — second-best in NFL. The Cowboys have allowed 7.6 yards per carry when defending on rushes to the left this season — worst in NFL.
The Cowboys are averaging just 2.3 yards per carry on rushes to the left side of the field this season — tied for second-worst in NFL. The 49ers have allowed just 3.4 yards per carry when defending on rushes to the left this season — fifth-best in NFL.
The Cowboys have thrown for just 5.1 yards per attempt on passes up the middle this season — second-worst in NFL. The 49ers have allowed just 3.1 yards per dropback when defending passes up the middle this season — best in NFL.
Dallas Cowboys Offense: Important Stats
The Cowboys have run 36% of their plays in the red zone in the 2nd half this season — best in NFL; League Avg: 15%.
The Cowboys have run 45% of their plays in the red zone in the 4th quarter this season — best in NFL; League Avg: 18%.
The Cowboys have run 65% of their plays in their opponent’s territory this season — best in NFL; League Avg: 44%.
The Cowboys have run 28% of their plays in the red zone this season — best in NFL; League Avg: 14%.
San Francisco 49ers Offense: Important Stats
The 49ers ran successful plays on 91% of pass attempts in Week 4 — best in NFL; League Avg: 47%.
The 49ers ran successful plays on 82% of plays in the 1st half in Week 4 — best in NFL; League Avg: 44%.
The 49ers ran successful plays on 69% of plays in Week 4 — best in NFL; League Avg: 42%.
The 49ers converted first downs on 27 of 53 plays (51%) in Week 4 — best in NFL; League Avg: 28%.
Dallas Cowboys Defense: Important Stats
The Cowboys defense has allowed scores on 5% of opponent drives in the 2nd half this season — best in NFL; League Avg: 34%.
The Cowboys defense has allowed scores on 23% of opponent drives in the 4th quarter since the 2021 season — 2nd-best in NFL; League Avg: 35%.
The Cowboys defense has allowed successful plays on 75% of plays in close and late situations this season — worst in NFL; League Avg: 41%.
The Cowboys defense has averaged 1.3 interceptions per game (49/38) since the 2021 season — best in NFL; League Avg: 0.8.
San Francisco 49ers Defense: Important Stats
Offenses facing the 49ers have thrown the ball 69% of the time (175 Pass Attempts/252 plays) this season — highest in NFL; League Avg: 53%.
The 49ers defense has allowed first downs on 67% of rush attempts in the red zone this season — worst in NFL; League Avg: 31%.
The 49ers defense has allowed successful plays on 26% of rush attempts in the 1st quarter since the 2022 season — best in NFL; League Avg: 42%.
The 49ers defense has allowed 76.0 rushing yards per game (1,597/21) since the 2022 season — best in NFL; League Avg: 120.7.
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