Cowboys vs. Lions Prediction: NFL Week 6 Odds, Betting Picks

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Dallas Cowboys quarterback Dak Prescott (4) reacts after a touchdown pass in the second half of an NFL football game against the Seattle Seahawks in Arlington, Texas, Thursday, Nov. 30, 2023.
(Roger Steinman/AP Photo)
Nick Hennion @nickhennion Oct 09, 2024, 5:12 PM
  • The Cowboys are 3-point underdogs against the Lions.
  • The Lions have won 10 straight games against opponents on a winning streak.
  • I predict the Lions will cover the spread on Sunday in Dallas.

Off a bye week seeking its third straight win, the Lions travel to Dallas for a meeting with the Cowboys. 

Prior to its bye week, Detroit captured a home win over the Seahawks on Monday Night Football. That moved them to 3-1 on the season after a road win over Arizona. 

Dallas has achieved positive results the last two weeks. After falling to Baltimore at home, the Cowboys earned wins over the Giants and Steelers to sit at 3-2. 

Bet on Cowboys vs. Lions and other NFL matchups with up-to-date NFL odds. 

NFL Week 6 Odds: Cowboys vs. Lions

SpreadTotal (O/U)Moneyline
Lions-3 (-115)52 (-110)-160
Cowboys+3 (-105)52 (-110)+135

Cowboys vs. Lions Prediction

Based on the extra rest for Detroit and their unlucky result last year in Dallas, my Lions vs. Cowboys prediction is the Detroit Lions Spread (-3). 

If you gave Dan Campbell truth serum and asked him which game on the schedule he wanted to win the most, wouldn’t this be it? 

Detroit famously went for two down a point last year in Dallas ….converted….and then had it called back after an offensive lineman failed to declare as eligible. 

But Detroit is on extended rest, while Dallas is far inferior to last year’s version. 

Campbell is 12-5-1 SU with eight or more days between games and 7-3-1 with 10 or more days to prepare, irrespective of whether they closed a favorite or underdog. 

Campbell is also 7-3 SU as a favorite of -3 or shorter, including five wins in his last six tries. 

On the other hand, Dallas is 0-2 SU against teams 10th or better in PFF’s rushing offense grades. 

Given the Lions are third in that metric, I’ll grab them now before it moves above a key number. 

Cowboys vs. Lions: NFL Public Betting Trends

Check back Friday for Cowboys vs. Lions public betting trends and data.

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About the Author

Nick Hennion

Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.