Guardians Division Odds

The Guardians odds to win the AL Central are +1400.

Guardians Playoff Odds

The Guardians odds to make the playoffs are -105. Their odds to miss the playoffs are -115.

Latest Stories

Guardians vs Tigers Prediction, Odds & Player Prop Bets Today – MLB, May 23

The Cleveland Guardians (+100) visit Comerica Park to take on the Detroit Tigers (-120) on Friday, May 23, 2025. First pitch is scheduled for 7:10pm EDT in Detroit, MI, MI. This season, the Guardians Read More

BetMGM Betting May 23, 2025

Guardians vs Tigers Prediction, Odds & Player Prop Bets Today – MLB, May 22

The Cleveland Guardians (+110) visit Comerica Park to take on the Detroit Tigers (-130) on Thursday, May 22, 2025. First pitch is scheduled for 6:40pm EDT in Detroit, MI. This season, the Guardians ar Read More

BetMGM Betting May 22, 2025

Guardians Payroll 2025: Total MLB Salary & Highest-Paid Players

Find out where the Cleveland Guardians rank in MLB payroll and the highest-paid players on their team this season. Read More

Shane Jackson May 21, 2025

Guardians vs Twins Prediction, Odds & Player Prop Bets Today – MLB, May 21

The Cleveland Guardians (-102) visit Target Field to take on the Minnesota Twins (-118) on Wednesday, May 21, 2025. First pitch is scheduled for 1:10pm EDT in Minneapolis, MN, MN. This season, the Gua Read More

BetMGM Betting May 21, 2025

Guardians vs Twins Prediction, Odds & Player Prop Bets Today – MLB, May 21

The Cleveland Guardians (-102) visit Target Field to take on the Minnesota Twins (-118) on Wednesday, May 21, 2025. First pitch is scheduled for 1:10pm EDT in Minneapolis, MN, MN. This season, the Gua Read More

BetMGM Betting May 21, 2025

Guardians vs Twins Prediction, Odds & Player Prop Bets Today – MLB, May 20

The Cleveland Guardians (-105) visit Target Field to take on the Minnesota Twins (-115) on Tuesday, May 20, 2025. First pitch is scheduled for 7:40pm EDT in Minneapolis, MN. This season, the Guardians Read More

BetMGM Betting May 20, 2025

Guardians vs Twins Prediction, Odds & Player Prop Bets Today – MLB, May 19

The Cleveland Guardians (+120) visit Target Field to take on the Minnesota Twins (-145) on Monday, May 19, 2025. First pitch is scheduled for 7:40pm EDT in Minneapolis, MN. This season, the Guardians Read More

BetMGM Betting May 19, 2025

Guardians vs Reds Prediction, Odds & Player Prop Bets Today – MLB, May 18

The Cleveland Guardians (+105) visit Great American Ball Park to take on the Cincinnati Reds (-125) on Sunday, May 18, 2025. First pitch is scheduled for 1:40pm EDT in Cincinnati, OH, OH. This season, Read More

BetMGM Betting May 18, 2025

Guardians vs Reds Prediction, Odds & Player Prop Bets Today – MLB, May 17

The Cleveland Guardians (-130) visit Great American Ball Park to take on the Cincinnati Reds (+105) on Saturday, May 17, 2025. First pitch is scheduled for 6:40pm EDT in Cincinnati, OH. This season, t Read More

BetMGM Betting May 17, 2025
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Guardians Odds Today

Jun 1 - 12 pm EST

Angels vs. Guardians

How To Bet on Guardians Odds

BetMGM has updated odds for the Cleveland Guardians, including run lines, moneylines, over/under totals, futures, parlays, and prop bets.

You can view all available odds at the online sportsbook throughout the offseason, spring training, regular season, and postseason.

Cleveland Guardians Futures Odds

Will the Guardians win the AL Central? Do they have a contender in AL Cy Young odds or AL MVP odds? What are their odds to make the postseason? These are some types of team and futures odds.

For example: If you bet $200 on the Guardians to make the postseason (-150), the bet would settle when Cleveland clinches a postseason berth or are eliminated from contention.

Cleveland Guardians Run Lines

If you bet on the run line (aka spread), youโ€™re betting on the final margin of the Guardians game.

For example, if you bet $5 on the Guardians -1.5 (+200) against the Detroit Tigers, Cleveland must win the game by at least two runs.

BetMGM also offers alternate run lines (aka alt spreads), for all MLB games. Instead of betting the Guardians -1.5 (+200), you could bet the Guardians -2.5 (+280).ย 

Cleveland Guardians Moneylines

Will the Guardians win the game? The margin of victory is irrelevant.

For example: If you bet $85 on the Guardians -175 against the Minnesota Twins, Cleveland must win the game.ย 

If the game ends in a tie, the bet is a push, which triggers a refund to your account balance.

Cleveland Guardians Over/Under Totals

How many combined runs will be scored by both teams? The final result of the game is irrelevant.

For example: If you bet $45 on the over 6.5 (-110) in the Guardians game against the Houston Astros, the teams must combine for at least seven runs.ย 

BetMGM also offers alternate over/under totals for all MLB games. Instead of betting over 6.5 (-110), you could bet over 8.5 (+250), a wager with a higher potential payout.

If the combined run total is identical to the over/under total, the bet is a push.

Cleveland Guardians Parlays

You can combine multiple Guardians bets into one parlay for more excitement and a bigger potential payout. If the bets are from the same game, itโ€™s called a Same Game Parlay.

For example: If you build a three-leg parlay with the Guardians moneyline (-125) against the Arizona Diamondbacks, Twinsโ€™ run line (-1.5, +180) against the Los Angles Dodgers, and over 9.5 (-115) in the Tigers’ game against the Chicago Cubs, you need all three legs to hit for your parlay to cash.

If one leg is a push, itโ€™s eliminated from the parlay. The odds (and payout) are recalculated without that leg.

You can also build multi-sport parlays with odds from other NBA games, NFL games, and more. And BetMGM regularly offers sportsbook promos for parlays, including Parlay Boosts, and Same Game Parlay Insurance.

Cleveland Guardians Prop Bets

Will a certain player hit a home run in tonightโ€™s game? How many strikeouts will the starting pitcher record?

BetMGM offers dozens of prop bets for each MLB game, including player props for pitcher hits allowed, player total bases, and more.

Run lines, moneylines, totals, parlays, and prop bets are just the start of daily MLB betting opportunities. You can also check out NRFI odds, First 5 Innings odds, and player vs. player stats.

Keep an eye on NRFI stats and records, First 5 Innings stats and records, and MLB ATS records for helpful betting stats.ย 

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