Cincinnati vs Iowa St. Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 12

Iowa State head coach Matt Campbell walks off the field after an NCAA college football game against Oklahoma, Saturday, Oct. 29, 2022, in Ames, Iowa. Oklahoma won 27-13. (AP Photo/Charlie Neibergall)
(AP Photo/Charlie Neibergall)
  • Iowa St. is a -9.5 point favorite vs. Cincinnati
  • Cincinnati vs. Iowa State Total (Over/Under): 53.5 points
  • TV Channel: FOX

The Cincinnati Bearcats (5-4) visit Jack Trice Stadium to take on the Iowa State Cyclones (7-2) on Nov. 16 in Ames, IA. Kickoff is scheduled for 8:00pm EST.

Iowa St. is a betting favorite in Week 12, with the spread sitting at -9.5 (-110).

The Cincinnati vs. Iowa State Over/Under is 53.5 total points.

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Cincinnati vs. Iowa State Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Cincinnati+9.5 -11053.5 -110+280
Iowa State -9.5 -11053.5 -110-350

Cincinnati vs Iowa State Prediction:

The winning team model predicts Iowa State will win this game with 75.1% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Cincinnati and Iowa St., key player performances this season and recent team trends.

Cincinnati vs Iowa State Spread Prediction:

Based on recent against-the-spread trends, the model predicts Iowa State will cover the spread with 74.7% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • Cincinnati has hit the 1Q Moneyline in 8 of their last 10 games (+6.50 Units / 52% ROI)
  • Cincinnati have covered the 1Q Spread in 8 of their last 10 games (+5.80 Units / 50% ROI)
  • Cincinnati has hit the 1H Game Total Over in 3 of their last 5 away games (+0.85 Units / 15% ROI)
  • Cincinnati has hit the 1Q Game Total Under in 3 of their last 5 away games (+0.75 Units / 13% ROI)
  • Cincinnati have covered the 1H Spread in 3 of their last 5 away games (+0.65 Units / 12% ROI)
  • Iowa State has hit the Moneyline in 8 of their last 11 games (+2.45 Units / 5% ROI)
  • Iowa State has hit the 1Q Game Total Over in 5 of their last 10 games (+1.90 Units / 17% ROI)
  • Iowa State have covered the 1Q Spread in 3 of their last 4 games at home (+1.80 Units / 35% ROI)
  • Iowa State has hit the Game Total Over in 7 of their last 12 games (+1.50 Units / 11% ROI)
  • Iowa State has hit the 1Q Moneyline in 3 of their last 4 games at home (+0.80 Units / 7% ROI)

We’ve highlighted some favorite college football player prop bets for Cincinnati players, looking at profitable historical betting trends:

Best Cincinnati Player Prop Bets Today

  • Corey Kiner has hit the Rushing Yards Over in his last 3 games (+3.00 Units / 83% ROI)
  • Xzavier Henderson has hit the Receiving Yards Under in his last 2 away games (+2.00 Units / 85% ROI)
  • Xzavier Henderson has hit the Receptions Under in his last game (+1.00 Units / 83% ROI)

Top NCAAF player prop bets for Iowa State players, looking at profitable historical betting trends:

Best Iowa State Player Prop Best Bets Today

  • Jaylon Jackson has hit the Rushing Yards Under in his last 3 games (+3.00 Units / 81% ROI)
  • Carson Hansen has hit the Rushing Yards Under in his last 2 games (+2.00 Units / 83% ROI)
  • Rocco Becht has hit the TD Passes Under in his last game (+1.00 Units / 100% ROI)
  • Rocco Becht has hit the Rushing Yards Under in his last game (+1.00 Units / 83% ROI)
  • Benjamin Brahmer has hit the Receiving Yards Over in his last game (+1.00 Units / 83% ROI)

Cincinnati Against the Spread (ATS) Record

Cincinnati is 4-4 against the spread this college football season (-0.4 Units / -4.06% ROI).

  • Cincinnati is 4-4 when betting on the Moneyline for -1.2 Units / -10.26% ROI
  • Cincinnati is 3-5 when betting the Over for -2.5 Units / -25.25% ROI
  • Cincinnati is 5-3 when betting the Under for +1.7 Units / 17.17% ROI

Iowa State Against the Spread (ATS) Record

Iowa St. is 5-4 against the spread this college football season (+0.6 Units / 6.12% ROI).

  • Iowa State is 6-2 when betting on the Moneyline for -0.35 Units / -0.81% ROI
  • Iowa State is 5-4 when betting the Over for +0.6 Units / 6.06% ROI
  • Iowa State is 4-5 when betting the Under for -1.5 Units / -15.15% ROI

Cincinnati: Keys to the Game vs. Iowa State

Cincinnati is 5-8 (.385) when having a turnover margin within one of the opposing team since the 2023 season– T-32nd-worst in FBS; Average: .537

Cincinnati is 4-12 (.250) when the opposing team converts 55% or more of its red zone chances into touchdowns since the 2023 season– T-6th-worst among Power Conference Teams; Average: .457

Cincinnati is 7-10 (.412) when the opposing team commits less than 60 yards in penalties since the 2023 season– 33rd-worst in FBS; Average: .536

Cincinnati is 2-8 (.200) when not forcing a fumble since the 2023 season– T-7th-worst in FBS; Average: .471

Iowa State: Keys to the Game vs. Cincinnati

Iowa State is winless (0-5) when intercepting no passes since the 2023 season– T-worst in FBS; Average: .353

Iowa State is winless (0-5) when intercepting no passes since the 2023 season– T-worst among Power Conference Teams; Average: .395

Iowa State is 10-3 (.769) when allowing less than 5 explosive passes since the 2023 season– 26th-best in FBS; Average: .617

Iowa State is 10-2 (.833) when rushing more than 30 times since the 2023 season– 15th-best among Power Conference Teams; Average: .671

Matchup Notes for Cincinnati vs. Iowa State

Iowa State’s offense has thrown for 20 or more yards on 13.9% of 287 attempts this season — 13th-best among FBS offenses. Cincinnati’s defense allowed 20+ yards on 14.2% of attempts this season — 6th-worst among FBS defenses.

Iowa State’s TEs has gained 391 yards on 28 receptions (14.0 YPR) this season — best among Big 12 TEs. Cincinnati’s defense has allowed 13.2 Yards Per Reception this season — 3rd-worst among Big 12 defenses.

Iowa State has gained 2,443 yards on 177 receptions (13.8 YPR) this season — T-best among Big 12 skill players. Cincinnati’s defense has allowed 13.2 Yards Per Reception this season — 3rd-worst among Big 12 defenses.

Cincinnati’s offense has thrown for 20 or more yards on just 6.6% of 302 attempts this season — T-5th-worst among FBS offenses. Iowa State’s defense allowed 20+ yards on just 7.4% of attempts this season — T-18th-best among FBS defenses.

Cincinnati’s TEs has gained 507 yards on 44 receptions (11.5 YPR) this season — 5th-best among Big 12 TEs. Iowa State’s defense has allowed just 9.7 Yards Per Reception to TEs this season — T-33rd-best among FBS defenses.

Cincinnati’s offense has thrown for 20 or more yards on just 6.6% of 302 attempts this season — T-5th-worst among FBS offenses. Iowa State’s defense allowed 20+ yards on just 7.4% of attempts this season — 3rd-best among Big 12 defenses.

Cincinnati Offensive Stats & Trends

Cincinnati’s offense has thrown for 20 or more yards on just 6.6% of 302 attempts this season — T-5th-worst among FBS offenses. Iowa State’s defense allowed 20+ yards on just 7.4% of attempts this season — T-18th-best among FBS defenses.

Cincinnati’s TEs has gained 507 yards on 44 receptions (11.5 YPR) this season — 5th-best among Big 12 TEs. Iowa State’s defense has allowed just 9.7 Yards Per Reception to TEs this season — T-33rd-best among FBS defenses.

Cincinnati RBs have averaged 9.3 yards from scrimmage per touch (308 yards / 33 touches) on 3rd down this season– 3rd-best among FBS Teams; Average: 5.7

Cincinnati’s offense has thrown for 20 or more yards on just 6.6% of 302 attempts this season — T-5th-worst among FBS offenses. Iowa State’s defense allowed 20+ yards on just 7.4% of attempts this season — 3rd-best among Big 12 defenses.

Cincinnati RBs have averaged 9.5 yards from scrimmage per touch (152 yards / 16 touches) on 3rd and short this season– 2nd-best among FBS Teams; Average: 4.5

Iowa State Offensive Stats & Trends

Iowa State’s offense has thrown for 20 or more yards on 13.9% of 287 attempts this season — 13th-best among FBS offenses. Cincinnati’s defense allowed 20+ yards on 14.2% of attempts this season — 6th-worst among FBS defenses.

Iowa State’s TEs has gained 391 yards on 28 receptions (14.0 YPR) this season — best among Big 12 TEs. Cincinnati’s defense has allowed 13.2 Yards Per Reception this season — 3rd-worst among Big 12 defenses.

Iowa State has gained 2,443 yards on 177 receptions (13.8 YPR) this season — T-best among Big 12 skill players. Cincinnati’s defense has allowed 13.2 Yards Per Reception this season — 3rd-worst among Big 12 defenses.

Iowa State has gained 2,443 yards on 177 receptions (13.8 YPR) this season — T-17th-best among FBS skill players. Cincinnati’s defense has allowed 13.2 Yards Per Reception this season — T-17th-worst among FBS defenses.

Iowa State has gained 2,443 yards on 177 receptions (13.8 YPR) this season — T-17th-best among FBS skill players. Cincinnati’s defense has allowed 13.2 Yards Per Reception this season — 3rd-worst among Big 12 defenses.

Cincinnati Bearcats Defensive Stats & Trends

Cincinnati has no interceptions and 20 TD passes allowed in the Red Zone since the 2023 season– T-worst in the Big 12; Average: 11.5

Cincinnati has allowed passes of 40+ yards on 23 of 581 attempts (4%) since the 2023 season– worst in the Big 12; Average: 2%

Cincinnati allowed passes of 40+ yards on 1 of 15 attempts (7%) last week– 2nd-worst in the Big 12; Average: 1%

Cincinnati has no interceptions (87 pass attempts) in the Red Zone since the 2023 season– T-worst in the Big 12; Average: 48.1

Cincinnati has no interceptions and 20 TD passes allowed in the Red Zone since the 2023 season– T-worst among Power Conference Teams; Average: 10.4

Iowa State Cyclones Defensive Stats & Trends

Iowa State opponents has averaged 6.5 Passing Attempts per TD (78 Pass Attempts/12 Passing TDs) in the Red Zone since the 2023 season– best in the Big 12; Average: 4.2

Iowa State has allowed a Completion Pct of just 36% (28 completions/78 attempts) in the Red Zone since the 2023 season– best among Power Conference Teams; Average: 53%

Iowa State opponents has averaged 6.5 Passing Attempts per TD (78 Pass Attempts/12 Passing TDs) in the Red Zone since the 2023 season– 2nd-best in FBS; Average: 3.9

Iowa State allowed 24.6 yards per completion (295 yards/12 completions) last week– worst among Power Conference Teams; Average: 11.6

Iowa State allowed passes of 40+ yards on 2 of 24 attempts (8%) last week– worst in the Big 12; Average: 1%


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