Louisville vs Virginia Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 7

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Virginia coach Tony Elliott reacts to a call on the field during the first half of the team's NCAA college football game against Duke in Durham, N.C., Saturday, Oct. 1, 2022.
(AP Photo/Ben McKeown)
BetMGM Betting @BETMGM Oct 11, 2024, 1:10 PM
  • The Louisville is a -7 point favorite vs. Virginia
  • The Louisville vs. Virginia Total (Over/Under): 54.5 points
  • TV Channel: ACCN

The Louisville Cardinals (3-2) visit David A. Harrison III Field at Scott Stadium to take on the Virginia Cavaliers (4-1) on Oct. 12 in Charlottesville, VA. Kickoff is scheduled for 3:30pm EDT.

Louisville is a betting favorite in Week 7, with the spread sitting at -7 (-110).

The Louisville vs. Virginia Over/Under is 54.5 total points.

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Louisville vs. Virginia Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Louisville-7 -11054.5 -110-275
Virginia +7 -11054.5 -110+225

Louisville vs Virginia Prediction:

The winning team model predicts Louisville will win this game with 69.2% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Louisville and Virginia, key player performances this season and recent team trends.

Louisville vs Virginia Spread Prediction:

Based on recent against-the-spread trends, the model predicts Virginia will cover the spread with 51.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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  • Louisville has hit the 1Q Moneyline in 5 of their last 9 games (+5.00 Units / 21% ROI)
  • Louisville have covered the 1Q Spread in 7 of their last 10 games (+3.85 Units / 32% ROI)
  • Louisville has hit the 1H Moneyline in 7 of their last 10 games (+3.10 Units / 6% ROI)
  • Louisville has hit the Game Total Over in 7 of their last 11 games (+2.60 Units / 21% ROI)
  • Louisville has hit the 1H Game Total Over in 3 of their last 4 away games (+2.00 Units / 46% ROI)
  • Virginia has hit the Moneyline in 4 of their last 9 games (+9.15 Units / 44% ROI)
  • Virginia has hit the 1Q Moneyline in 5 of their last 8 games (+6.85 Units / 79% ROI)
  • Virginia has hit the 1Q Game Total Under in their last 4 games at home (+4.00 Units / 87% ROI)
  • Virginia has hit the Game Total Over in 6 of their last 9 games (+3.80 Units / 38% ROI)
  • Virginia have covered the 1Q Spread in 3 of their last 4 games at home (+2.15 Units / 43% ROI)

Top NCAAF player prop bets for Virginia players, looking at profitable historical betting trends:

Best Virginia Player Prop Best Bets Today

  • Tony Muskett has hit the Passing Yards Under in his last game (+1.00 Units / 83% ROI)
  • Malachi Fields has hit the Receiving Yards Over in his last game (+1.00 Units / 83% ROI)
  • Kobe Pace has hit the Rushing Yards Under in his last game (+1.00 Units / 83% ROI)
  • Tony Muskett has hit the TD Passes Under in his last game (+1.00 Units / 47% ROI)

Louisville Against the Spread (ATS) Record

Louisville is 3-0 against the spread this college football season (+3 Units / 67.42% ROI).

  • Louisville is 1-0 when betting on the Moneyline for +1 Units / 22.47% ROI
  • Louisville is 2-1 when betting the Over for +0.9 Units / 20.45% ROI
  • Louisville is 1-2 when betting the Under for -1.2 Units / -27.27% ROI

Virginia Against the Spread (ATS) Record

Virginia is 1-1 against the spread this college football season (-0.1 Units / -2.27% ROI).

  • Virginia is 2-1 when betting on the Moneyline for +0.65 Units / 4% ROI
  • Virginia is 1-2 when betting the Over for -1.2 Units / -27.27% ROI
  • Virginia is 2-1 when betting the Under for +0.9 Units / 20.45% ROI

Louisville: Keys to the Game vs. Virginia

Louisville is 12-4 (.750) when making 7 or more explosive plays since the 2023 season– T-36th-best in FBS; Average: .649

Louisville is 12-1 (.923) when allowing less than 3 sacks since the 2023 season– T-6th-best in FBS; Average: .646

Louisville is 11-4 (.733) when having a turnover margin within one of the opposing team since the 2023 season– T-25th-best in FBS; Average: .543

Louisville is 10-5 (.667) when committing less than 60 yards in penalties since the 2023 season– T-32nd-best in FBS; Average: .534

Virginia: Keys to the Game vs. Louisville

Virginia is 1-7 (.125) when not forcing a fumble since the 2023 season– worst among Power Conference Teams; Average: .537

Virginia is 1-7 (.125) when not forcing a fumble since the 2023 season– T-5th-worst in FBS; Average: .485

Virginia is 3-8 (.273) when allowing 7 or more explosive plays since the 2023 season– T-38th-worst in FBS; Average: .414

Virginia is 6-10 (.375) when allowing 10 or more rushes of four or more yards since the 2023 season– T-13th-worst among Power Conference Teams; Average: .542

Matchup Notes for Louisville vs. Virginia

Virginia’s TEs has gained 228 yards on 17 receptions (13.4 YPR) this season — 4th-best among ACC TEs. Louisville’s defense has allowed 13.0 Yards Per Reception to TEs this season — T-29th-worst among FBS defenses.

Virginia’s WRs has 265 receptions in 17 games (15.6 per game) since the 2023 season — 2nd-best among ACC WRs. Louisville’s defense has allowed just 16.9 receptions per game since the 2023 season — 26th-best among FBS defenses.

Virginia’s TEs has gained 228 yards on 17 receptions (13.4 YPR) this season — 4th-best among ACC TEs. Louisville’s defense has allowed just 11.0 Yards Per Reception this season — T-3rd-best among ACC defenses.

Louisville’s offense has thrown for 1,517 passing yards in 5 games (303.4 YPG) this season — 14th-best among FBS offenses. Virginia’s defense has allowed 266.4 passing yards per game this season — 16th-worst among FBS defenses.

Louisville’s offense has thrown for 1,517 passing yards in 5 games (303.4 YPG) this season — 14th-best among FBS offenses. Virginia’s defense has allowed 266.4 passing yards per game this season — 3rd-worst among ACC defenses.

Louisville’s RBs has rushed for 3,136 yards on 513 carries (6.1 YPC) since the 2023 season — T-5th-best among FBS RBs. Virginia’s defense have allowed 4.6 YPC since the 2023 season — T-27th-worst among FBS defenses.

Louisville Offensive Stats & Trends

Louisville’s offense has thrown for 1,517 passing yards in 5 games (303.4 YPG) this season — 14th-best among FBS offenses. Virginia’s defense has allowed 266.4 passing yards per game this season — 16th-worst among FBS defenses.

Louisville’s offense has thrown for 1,517 passing yards in 5 games (303.4 YPG) this season — 14th-best among FBS offenses. Virginia’s defense has allowed 266.4 passing yards per game this season — 3rd-worst among ACC defenses.

Louisville’s RBs has rushed for 3,136 yards on 513 carries (6.1 YPC) since the 2023 season — T-5th-best among FBS RBs. Virginia’s defense have allowed 4.6 YPC since the 2023 season — T-27th-worst among FBS defenses.

Louisville’s TEs has 22 receptions in 5 games (4.4 per game) this season — T-5th-best among ACC TEs. Virginia’s defense has allowed 21.2 receptions per game this season — T-25th-worst among FBS defenses.

Louisville WRs have averaged 29.2 yards per reception (234 yards/8 catches) on 3rd and long this season– 4th-best among Power Conference Teams; Average: 15.3

Virginia Offensive Stats & Trends

Virginia’s TEs has gained 228 yards on 17 receptions (13.4 YPR) this season — 4th-best among ACC TEs. Louisville’s defense has allowed 13.0 Yards Per Reception to TEs this season — T-29th-worst among FBS defenses.

Virginia’s WRs has 265 receptions in 17 games (15.6 per game) since the 2023 season — 2nd-best among ACC WRs. Louisville’s defense has allowed just 16.9 receptions per game since the 2023 season — 26th-best among FBS defenses.

Virginia’s TEs has gained 228 yards on 17 receptions (13.4 YPR) this season — 4th-best among ACC TEs. Louisville’s defense has allowed just 11.0 Yards Per Reception this season — T-3rd-best among ACC defenses.

Virginia’s WRs has 265 receptions in 17 games (15.6 per game) since the 2023 season — 2nd-best among ACC WRs. Louisville’s defense has allowed just 16.9 receptions per game since the 2023 season — 4th-best among ACC defenses.

Virginia’s WRs has 265 receptions in 17 games (15.6 per game) since the 2023 season — T-27th-best among FBS WRs. Louisville’s defense has allowed just 16.9 receptions per game since the 2023 season — 26th-best among FBS defenses.

Louisville Cardinals Defensive Stats & Trends

Louisville has allowed a Completion Pct of just 41% (26 completions/63 attempts) in close and late situations since the 2023 season– best among Power Conference Teams; Average: 58%

Louisville has allowed a Completion Pct of just 36% (5 completions/14 attempts) on 3rd and long this season– 3rd-best among Power Conference Teams; Average: 55%

Louisville has allowed opponents to catch just 5 of 14 passes (36% Reception Pct) on 3rd and long this season– 3rd-best among Power Conference Teams; Average: 56%

Louisville has allowed a Completion Pct of just 41% (26 completions/63 attempts) in close and late situations since the 2023 season– best in FBS; Average: 58%

Louisville has allowed 63.0 yards from scrimmage per game to RBs this season– best among Power Conference Teams; Average: 126.2

Virginia Cavaliers Defensive Stats & Trends

Virginia has sacked opposing QBs on just 4% of pass attempts (23/548) since the 2023 season– 2nd-worst among Power Conference Teams; Average: 7%

Virginia has sacked opposing QBs on just 4% of pass attempts (23/548) since the 2023 season– T-3rd-worst in FBS; Average: 7%

Virginia sacked opposing QBs on just 3% of pass attempts (11/377) in the 2023 season– 2nd-worst among Power Conference Teams; Average: 7%

Virginia has averaged a sack every 23.8 pass attempts (548 Pass Attempts/23 Sacks) since the 2023 season– T-3rd-worst in FBS; Average: 14.4

Virginia averaged a sack every 34.3 pass attempts (377 Pass Attempts/11 Sacks) in the 2023 season– 2nd-worst among Power Conference Teams; Average: 13.8


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