Ohio State vs Penn State Prediction, Odds & Best Prop Bets โ€“ NCAAF, Week 10

Penn State quarterback Drew Allar (15) runs with the ball against Rutgers during the second half of an NCAA college football game Saturday, Nov. 19, 2022, in Piscataway, N.J. Penn State won 55-10. (AP Photo/Adam Hunger)
(AP Photo/Adam Hunger)
  • Ohio State is a -3.5 point favorite vs. Penn State
  • Ohio State vs. Penn State Total (Over/Under): 46.5 points
  • TV Channel: FOX

The Ohio State Buckeyes (6-1) visit Beaver Stadium to take on the Penn State Nittany Lions (7-0) on Nov. 2 in University Park, PA. Kickoff is scheduled for 12:00pm EDT.

Ohio State is a betting favorite in Week 10, with the spread sitting at -3.5 (-115).

The Ohio State vs. Penn State Over/Under is 46.5 total points.

Bet now on Penn State vs Ohio State & all NCAAF games with BetMGM

Ohio State vs. Penn State Odds, Spread, Over/Under:

SpreadTotal (O/U)Moneyline
Ohio State-3.5 -11546.5 -115-185
Penn State +3.5 -10546.5 -105+150

Ohio State vs Penn State Prediction:

The winning team model predicts Ohio State will win this game with 61.1% confidence, based on game simulations, offensive & defensive matchups and recent game results.

This winning team prediction factors in up-to-date player injuries for both Ohio State and Penn State, key player performances this season and recent team trends.

Ohio State vs Penn State Spread Prediction:

Based on recent against-the-spread trends, the model predicts Penn State will cover the spread with 67.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


Bet now on Penn State vs Ohio State and all games with BetMGM


  • Ohio State has hit the 1Q Moneyline in 7 of their last 8 games (+6.00 Units / 15% ROI)
  • Ohio State has hit the Moneyline in 9 of their last 12 games (+4.45 Units / 0% ROI)
  • Ohio State has hit the Game Total Over in 3 of their last 4 away games (+1.90 Units / 43% ROI)
  • Ohio State has hit the 1H Game Total Over in 3 of their last 4 away games (+1.75 Units / 39% ROI)
  • Ohio State has hit the 1Q Game Total Under in 6 of their last 11 games (+1.75 Units / 14% ROI)
  • Penn State has hit the Moneyline in 10 of their last 12 games (+6.80 Units / 0% ROI)
  • Penn State has hit the Game Total Under in 8 of their last 12 games (+3.60 Units / 27% ROI)
  • Penn State has hit the 1Q Game Total Under in 6 of their last 11 games (+1.30 Units / 10% ROI)
  • Penn State has hit the 1H Game Total Under in 4 of their last 7 games at home (+0.75 Units / 10% ROI)

We’ve highlighted some favorite college football player prop bets for Ohio State players, looking at profitable historical betting trends:

Best Ohio State Player Prop Bets Today

  • Will Howard has hit the TD Passes Over in his last 2 games (+2.40 Units / 96% ROI)
  • TreVeyon Henderson has hit the Receiving Yards Under in his last 2 games (+2.00 Units / 83% ROI)
  • Will Howard has hit the Rushing Yards Under in his last 2 games (+2.00 Units / 83% ROI)
  • Quinshon Judkins has hit the Rushing Yards Under in his last 2 games (+2.00 Units / 83% ROI)
  • Carnell Tate has hit the Receiving Yards Over in his last game (+1.00 Units / 83% ROI)

Top NCAAF player prop bets for Penn State players, looking at profitable historical betting trends:

Best Penn State Player Prop Best Bets Today

  • Harrison Wallace III has hit the Receiving Yards Over in his last 3 games (+3.00 Units / 83% ROI)
  • Nicholas Singleton has hit the Rushing Yards Under in his last 2 games (+2.00 Units / 83% ROI)
  • Drew Allar has hit the Rushing Yards Over in his last 2 games (+2.00 Units / 83% ROI)
  • Tyler Warren has hit the Receptions Over in his last game (+1.05 Units / 105% ROI)
  • Julian Fleming has hit the Receiving Yards Under in his last game (+1.00 Units / 74% ROI)

Ohio State Against the Spread (ATS) Record

Ohio State is 3-4 against the spread this college football season (-1.4 Units / -18.18% ROI).

  • Ohio State is 6-1 when betting on the Moneyline for +4.25 Units / 0.22% ROI
  • Ohio State is 4-3 when betting the Over for +0.7 Units / 9.09% ROI
  • Ohio State is 3-4 when betting the Under for -1.4 Units / -18.18% ROI

Penn State Against the Spread (ATS) Record

Penn State is 3-4 against the spread this college football season (-1.4 Units / -18.18% ROI).

  • Penn State is 7-0 when betting on the Moneyline for +7 Units / 0.51% ROI
  • Penn State is 2-5 when betting the Over for -3.5 Units / -45.45% ROI
  • Penn State is 5-2 when betting the Under for +2.8 Units / 36.36% ROI

Ohio State: Keys to the Game vs. Penn State

Ohio State is 12-2 (.857) when making 3 or more explosive runs in a game since the 2023 season– T-18th-best in FBS; Average: .646

Ohio State is 16-2 (.889) when allowing less than 200 passing yards since the 2023 season– 10th-best among Power Conference Teams; Average: .697

Ohio State is 10-2 (.833) when having a turnover margin within one of the opposing team since the 2023 season– T-8th-best among Power Conference Teams; Average: .600

Ohio State is 14-1 (.933) when rushing for 120 or more yards since the 2023 season– 7th-best among Power Conference Teams; Average: .714

Penn State: Keys to the Game vs. Ohio State

Penn State is undefeated (13-0) when intercepting at least 1 pass since the 2023 season– T-best in FBS; Average: .674

Penn State is undefeated (7-0) when rushing at least 4 yards in a play 10 or more times this season– T-best in FBS; Average: .596

Penn State is 12-1 (.923) when not losing a fumble since the 2023 season– T-6th-best among Power Conference Teams; Average: .662

Penn State is 8-3 (.727) when the opposing team rushes more than 30 times since the 2023 season– T-14th-best in FBS; Average: .447

Matchup Notes for Ohio State vs. Penn State

Penn State’s offense has thrown for 20 or more yards on 13.8% of 189 attempts this season — 16th-best among FBS offenses. Ohio State’s defense allowed 20+ yards on just 7.0% of attempts this season — T-14th-worst among FBS defenses.

Penn State’s QBs has thrown for 1,840 passing yards in 7 games (262.9 YPG) this season — 34th-best among FBS teams. Ohio State’s defense has allowed just 163.1 passing yards per game this season — 8th-best among FBS defenses.

Penn State’s WRs has gained 1,008 yards on 59 receptions (17.1 YPR) this season — best among Big Ten WRs. Ohio State’s defense has allowed just 9.6 Yards Per Reception this season — 7th-best among FBS defenses.

Ohio State’s WRs has gained 1,677 yards on 114 receptions (14.7 YPR) this season — T-3rd-best among Big Ten WRs. Penn State’s defense has allowed just 10.0 Yards Per Reception this season — T-11th-best among FBS defenses.

Ohio State’s TEs has gained 213 yards on 18 receptions (11.8 YPR) this season — 4th-best among Big Ten TEs. Penn State’s defense has allowed just 10.0 Yards Per Reception this season — T-11th-best among FBS defenses.

Ohio State has gained 1,987 yards on 149 receptions (13.3 YPR) this season — T-25th-best among FBS skill players. Penn State’s defense has allowed just 10.0 Yards Per Reception this season — 4th-best among Big Ten defenses.

Ohio State Offensive Stats & Trends

Ohio State’s WRs has gained 1,677 yards on 114 receptions (14.7 YPR) this season — T-3rd-best among Big Ten WRs. Penn State’s defense has allowed just 10.0 Yards Per Reception this season — T-11th-best among FBS defenses.

Ohio State’s TEs has gained 213 yards on 18 receptions (11.8 YPR) this season — 4th-best among Big Ten TEs. Penn State’s defense has allowed just 10.0 Yards Per Reception this season — T-11th-best among FBS defenses.

Ohio State has gained 1,987 yards on 149 receptions (13.3 YPR) this season — T-25th-best among FBS skill players. Penn State’s defense has allowed just 10.0 Yards Per Reception this season — 4th-best among Big Ten defenses.

Ohio State’s WRs has gained 1,677 yards on 114 receptions (14.7 YPR) this season — T-3rd-best among Big Ten WRs. Penn State’s defense has allowed just 11.2 Yards Per Reception to WRs this season — T-15th-best among FBS defenses.

Ohio State has gained 1,987 yards on 149 receptions (13.3 YPR) this season — 3rd-best among Big Ten skill players. Penn State’s defense has allowed just 10.0 Yards Per Reception this season — T-11th-best among FBS defenses.

Penn State Offensive Stats & Trends

Penn State’s offense has thrown for 20 or more yards on 13.8% of 189 attempts this season — 16th-best among FBS offenses. Ohio State’s defense allowed 20+ yards on just 7.0% of attempts this season — T-14th-worst among FBS defenses.

Penn State WRs have averaged 41.5 yards per reception (83 yards/2 catches) on 3rd and long this season– 2nd-best among FBS Teams; Average: 14.6

Penn State’s QBs has thrown for 1,840 passing yards in 7 games (262.9 YPG) this season — 34th-best among FBS teams. Ohio State’s defense has allowed just 163.1 passing yards per game this season — 8th-best among FBS defenses.

Penn State WRs have averaged 41.5 yards per reception (83 yards/2 catches) on 3rd and long this season– best among Big Ten Teams; Average: 14.1

Penn State’s WRs has gained 1,008 yards on 59 receptions (17.1 YPR) this season — best among Big Ten WRs. Ohio State’s defense has allowed just 9.6 Yards Per Reception this season — 7th-best among FBS defenses.

Ohio State Buckeyes Defensive Stats & Trends

Ohio State opponents has averaged 43.2 Passing Attempts per TD (561 Pass Attempts/13 Passing TDs) since the 2023 season– best among Power Conference Teams; Average: 21.8

Ohio State has allowed 11 rushing TDs on 677 carries (61.5 Carries Per TD) since the 2023 season– 2nd-best in FBS; Average: 23.9

Ohio State opponents has averaged 43.2 Passing Attempts per TD (561 Pass Attempts/13 Passing TDs) since the 2023 season– best in FBS; Average: 20.5

Ohio State has allowed just 152.0 receiving yards per game (3,039/20) since the 2023 season– best in FBS; Average: 221.3

Ohio State has allowed 152.0 Passing Yards per game (3,039/20) since the 2023 season– best among Power Conference Teams; Average: 218.9

Penn State Nittany Lions Defensive Stats & Trends

Penn State has allowed 2 rushing TDs on 25 carries (12.5 Carries Per TD) in the Red Zone this season– T-2nd-best among Power Conference Teams; Average: 5

Penn State has sacked opposing QBs on 12% of pass attempts (64/553) since the 2023 season– best in the Big Ten; Average: 7%

Penn State sacked opposing QBs on 15% of pass attempts (50/340) in the 2023 season– best in the Big Ten; Average: 8%

Penn State has tackled opponents for a loss on 154 of 639 rushing attempts (24% TFL%) since the 2023 season– best among Power Conference Teams; Average: 16%.

Penn State has allowed 2 rushing TDs on 25 carries (12.5 Carries Per TD) in the Red Zone this season– T-3rd-best in FBS; Average: 4.6


Bet now on Penn State vs Ohio State and all games with BetMGM


More College Football Betting at BetMGM

BetMGM is the best online sportsbook for college football betting.

Whether youโ€™re a first-time bettor checking out the best sportsbook promos, a casual fan betting on Georgia football national championship odds, Michigan football odds, or Ohio State playoff odds, or a longtime diehard breaking down trends for live sports betting, there are entertainment options for everyone.

Visit the sportsbook today to place a college football bet online!

BetMGM First Bet Offer
About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.