49ers vs Packers Prediction, Odds & Best Prop Bets โ€“ NFL, Week 12

Green Bay Packers' Jordan Love warms up before an NFL football game against the Minnesota Vikings Sunday, Dec. 31, 2023, in Minneapolis. (AP Photo/Abbie Parr)
(AP Photo/Abbie Parr)
  • The Packers are -2.5 point favorites vs the 49ers
  • Total (Over/Under): 47.5 points
  • Watch this game on FOX

The San Francisco 49ers (5-5-0) visit Lambeau Field to take on the Green Bay Packers (7-3-0) on Nov. 24. Kickoff is scheduled for 4:25pm EST in Green Bay, WI.

The Packers are betting favorites in this matchup, with the spread sitting at -2.5 (-110).

The 49ers vs. Packers Over/Under is 47.5 total points for the game.

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49ers vs. Packers Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
49ers+2.5 -11047.5 -110+115
Packers -2.5 -11047.5 -110-140

49ers vs. Packers Prediction

The winning team model predicts the 49ers will win this game with 54.0% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

49ers vs Packers Spread Prediction

Based on recent against-the-spread trends, the model predicts the 49ers will cover the spread with 68.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for 49ers players this playoff game, looking at profitable historical betting trends:

Best 49ers Player Prop Bets Today

  • Brock Purdy has hit the Rushing Yards Over in 13 of his last 18 games (+7.50 Units / 37% ROI)
  • Jauan Jennings has hit the Receptions Over in 10 of his last 14 games (+6.25 Units / 37% ROI)
  • Brandon Aiyuk has hit the Receiving Yards Under in 11 of his last 15 games (+6.25 Units / 36% ROI)
  • Christian McCaffrey has hit the Longest Rush Over in 7 of his last 8 games (+5.85 Units / 63% ROI)
  • George Kittle has hit the Longest Reception Over in 6 of his last 7 games (+4.85 Units / 60% ROI)

And here are some top NFL player prop bets for Packers players for this matchup, looking at profitable historical betting trends:

Best Packers Player Prop Best Bets Today

  • Jordan Love has hit the TD Passes Over in 12 of his last 16 games (+8.55 Units / 41% ROI)
  • Tucker Kraft has hit the Receiving Yards Over in 12 of his last 18 games (+5.40 Units / 27% ROI)
  • Tucker Kraft has hit the Receptions Over in 12 of his last 18 games (+5.40 Units / 24% ROI)
  • Jordan Love has hit the Pass Attempts Under in 11 of his last 16 games (+5.25 Units / 27% ROI)
  • Jordan Love has hit the Passing Yards Over in 11 of his last 16 games (+5.20 Units / 28% ROI)
  • The San Francisco 49ers have hit the 3Q Game Total Over in 14 of their last 19 games (+7.75 Units / 32% ROI)
  • The San Francisco 49ers have covered the 1Q Spread in 8 of their last 10 away games (+6.15 Units / 55% ROI)
  • The San Francisco 49ers have hit the 2H Game Total Over in 11 of their last 16 games (+5.43 Units / 31% ROI)
  • The San Francisco 49ers have hit the 1H Moneyline in 8 of their last 10 away games (+5.20 Units / 21% ROI)
  • The San Francisco 49ers have hit the 1Q Moneyline in 7 of their last 10 away games (+4.20 Units / 22% ROI)
  • The Green Bay Packers have hit the 1Q Moneyline in 16 of their last 21 games (+12.15 Units / 44% ROI)
  • The Green Bay Packers have covered the 1Q Spread in 16 of their last 21 games (+11.50 Units / 44% ROI)
  • The Green Bay Packers have hit the Moneyline in 14 of their last 21 games (+8.95 Units / 29% ROI)
  • The Green Bay Packers have hit the 4Q Game Total Under in 13 of their last 18 games (+7.25 Units / 34% ROI)
  • The Green Bay Packers have hit the 3Q Game Total Over in 12 of their last 18 games (+5.85 Units / 27% ROI)

49ers Against the Spread (ATS) Record

Against the spread this NFL season, the 49ers art 4-6 (-2.5 Units / -22.94% ROI).

  • 49ers are 5-5 when betting on the Moneyline for -7.25 Units / -26.56% ROI
  • 49ers are 5-5 when betting the Over for -0.5 Units / -4.55% ROI
  • 49ers are 5-5 when betting the Under for -0.5 Units / ROI

Packers Against the Spread (ATS) Record

Against the spread this NFL season, the Packers are 4-6 (-2.65 Units / -23.98% ROI).

  • Packers are 7-3 when betting on the Moneyline for +4.1 Units / 26.37% ROI
  • Packers are 4-5 when betting the Over for -1.5 Units / -13.64% ROI
  • Packers are 5-4 when betting the Under for +0.6 Units / 5.45% ROI

San Francisco 49ers: Keys to the Game vs. the Green Bay Packers

The 49ers were winless (0-3) when within 7 points at the two minute warning last season — worst in NFL; League Avg: .500.

The 49ers were winless (0-5) when scoring less than 22 points last season — T-worst in NFL; League Avg: .253.

The 49ers were winless (0-4) when trailing at the end of the third quarter last season — T-worst in NFL; League Avg: .148.

The 49ers were 2-1 (.667) when not forcing a turnover last season — T-4th-best in NFL; League Avg: .265.

Green Bay Packers: Keys to the Game vs. the San Francisco 49ers

The Packers are 4-1 (.800) when within 7 points at the two minute warning this season — T-2nd-best in NFL; League Avg: .500.

The Packers were 1-6 (.143) when throwing at least 1 interception last season — T-4th-worst in NFL; League Avg: .371.

The Packers are undefeated (6-0) when committing less than 60 yards in penalties this season — T-best in NFL; League Avg: .504.

The Packers are 6-2 (.750) when rushing for more than 100 yards this season — T-9th-best in NFL; League Avg: .627.

Additional Matchup Notes for San Francisco 49ers vs. Green Bay Packers

The Packers have a third down conversion rate of 23.9% on 3rd and 10+ YTG since the 2023 season — 3rd-best in NFL. The 49ers defense has allowed a third down conversion rate of 22.5% on 3rd and 10+ YTG since the 2023 season — 3rd-worst in NFL.

The Packers have run successful plays on just 38.6% of pass attempts on their opponent’s side of the field this season — 5th-worst in NFL. The 49ers have allowed successful plays on just 43.2% of pass attempts on their own side of the field this season — T-5th-best in NFL.

The Packers went three and out on 0% of their drives last week — T-best in NFL. The 49ers forced three and outs on 0% of opponent drives last week — T-worst in NFL.

The 49ers have run successful plays on 53.4% of pass attempts against a base front since the 2023 season — best in NFL. The Packers have allowed successful plays on 50.4% of pass attempts with a base front since the 2023 season — 3rd-worst in NFL.

The 49ers have been successful on 49.3% of plays they have ran since the 2023 season — best in NFL. The Packers have allowed their opponents to be successful on 44.7% of plays since the 2023 season — 4th-worst in NFL.

The 49ers have run successful plays on 47.4% of pass attempts on their opponent’s side of the field since the 2023 season — 3rd-best in NFL. The Packers have allowed successful plays on 51.8% of pass attempts on their own side of the field since the 2023 season — 2nd-worst in NFL.

San Francisco 49ers Offense: Important Stats

The 49ers ran successful plays on 21% of rush attempts against a light front last season — worst in NFL; League Avg: 47%.

The 49ers ran successful plays on 53% of plays against a base front last season — best in NFL; League Avg: 42%.

The 49ers completed passes for 20+ yards on 75 of their 491 total passing attempts (15%) last season — best in NFL; League Avg: 9%.

The 49ers ran successful plays on 51% of plays last season — best in NFL; League Avg: 42%.

Green Bay Packers Offense: Important Stats

The Packers have run successful plays on 0% of plays against a light rush this season — worst in NFL; League Avg: 40%.

The Packers have run successful plays on 0% of pass attempts against a light rush this season — worst in NFL; League Avg: 41%.

The Packers targeted RBs 41% of the time (7 Pass Attempts/17 plays) in Week 11 — highest in NFL; League Avg: 16%.

The Packers ran 53% of their plays in their opponent’s territory in the 3rd quarter last season — best in NFL; League Avg: 41%.

San Francisco 49ers Defense: Important Stats

The 49ers defense allowed successful plays on 10% of plays with a light rush last season — best in NFL; League Avg: 39%.

The 49ers defense has not allowed a successful play on any pass attempt on contested throws since Week 8 — best in NFL; League Avg: 37%.

The 49ers defense have allowed -0.50 epa per play with a light rush since the 2023 season — 2nd-best in NFL; League Avg: -0.02.

The 49ers defense has allowed successful plays on 15% of plays with a light rush since the 2023 season — 2nd-best in NFL; League Avg: 39%.

Green Bay Packers Defense: Important Stats

The Packers defense has allowed a passer rating of just 34.4 on 3rd and long (39 Pass Attempts) this season — 2nd-best in NFL; League Avg: 83.0.

The Packers defense has allowed successful plays on 51% of pass attempts with a base rush since the 2023 season — 2nd-worst in NFL; League Avg: 46%.

The Packers defense averaged 0.4 interceptions per game (7/17) last season — T-worst in NFL; League Avg: 0.8.

The Packers defense has allowed successful plays on 58% of pass attempts first read passes since the 2023 season — T-worst in NFL; League Avg: 52%.

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About the Author

Nick Hennion

Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.