Cardinals vs Rams Prediction, Odds & Best Prop Bets โ€“ NFL, Week 17

Los Angeles Rams quarterback Matthew Stafford drops back to pass during an NFL football game against the Seattle Seahawks, Sunday, Sept. 10, 2023, in Seattle. The Rams won 30-13.
(Stephen Brashear/AP Photo)
  • The Rams are -6.5 point favorites vs the Cardinals
  • Total (Over/Under): 48 points
  • Watch this game on NFLN

The Arizona Cardinals (7-8-0) visit SoFi Stadium to take on the Los Angeles Rams (9-6-0) on Dec. 28. Kickoff is scheduled for 8:10pm EST in Inglewood, CA.

The Rams are betting favorites in this matchup, with the spread sitting at -6.5 (-110).

The Cardinals vs. Rams Over/Under is 48 total points for the game.

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Cardinals vs. Rams Odds, Spread, Over/Under

SpreadTotal (O/U)Moneyline
Cardinals+6.5 -11048 -110+225
Rams -6.5 -11048 -110-275

Cardinals vs. Rams Prediction

The winning team model predicts the Rams will win this game with 57.0% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.

Cardinals vs Rams Spread Prediction

Based on recent against-the-spread trends, the model predicts the Cardinals will cover the spread with 55.0% confidence.

This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.


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We’ve highlighted some favorite NFL player prop bets for Cardinals players this playoff game, looking at profitable historical betting trends:

Best Cardinals Player Prop Bets Today

  • Marvin Harrison Jr. has hit the Receptions Under in 11 of his last 15 games (+7.30 Units / 39% ROI)
  • James Conner has hit the Receptions Over in 11 of his last 17 games (+6.30 Units / 31% ROI)
  • Kyler Murray has hit the TD Passes Under in 13 of his last 17 games (+6.10 Units / 22% ROI)
  • Marvin Harrison Jr. has hit the Receiving Yards Under in 9 of his last 12 games (+5.70 Units / 42% ROI)
  • Chad Ryland has hit the Field Goals Over in 6 of his last 7 away games (+5.45 Units / 78% ROI)

And here are some top NFL player prop bets for Rams players for this matchup, looking at profitable historical betting trends:

Best Rams Player Prop Best Bets Today

  • Demarcus Robinson has hit the Receptions Under in 13 of his last 16 games (+9.30 Units / 42% ROI)
  • Matthew Stafford has hit the Rushing Yards Under in 9 of his last 10 games (+7.65 Units / 49% ROI)
  • Kyren Williams has hit the Receiving Yards Under in 11 of his last 16 games (+5.30 Units / 29% ROI)
  • Demarcus Robinson has hit the Receiving Yards Under in 6 of his last 7 games at home (+4.85 Units / 61% ROI)
  • Joshua Karty has hit the Field Goals Under in 5 of his last 6 games at home (+4.00 Units / 58% ROI)

First Touchdown Scorer Bet for Rams vs Cardinals

Player Name 1st TD Odds
Kyren Williams (LAR) +350
James Conner (Ari) +600
Puka Nacua (LAR) +650
DeeJay Dallas (ARI) +750
Trey Benson (ARI) +800

Receiving Props: Total Receiving Yards for Rams vs Cardinals

Player Name Over Under
Marvin Harrison Jr. (ARI) 50.5 -120 50.5 -110
Kyren Williams (LAR) 9.5 -110 9.5 -120
Cooper Kupp (LAR) 53.5 -115 53.5 -120
Puka Nacua (LAR) 86.5 -115 86.5 -115

Rushing Props: Total Rushing Yards for Rams vs Cardinals

Player Name Over Under
Kyren Williams (LAR) 95.5 -115 95.5 -115
  • The Arizona Cardinals have hit the 3Q Moneyline in 10 of their last 17 games (+6.45 Units / 32% ROI)
  • The Arizona Cardinals have covered the 2H Spread in 10 of their last 14 games (+6.23 Units / 39% ROI)
  • The Arizona Cardinals have hit the 2H Moneyline in 7 of their last 9 games (+5.93 Units / 54% ROI)
  • The Arizona Cardinals have hit the 4Q Moneyline in 9 of their last 17 games (+5.10 Units / 26% ROI)
  • The Arizona Cardinals have covered the 3Q Spread in 11 of their last 17 games (+4.40 Units / 21% ROI)
  • The Los Angeles Rams have hit the Moneyline in 13 of their last 20 games (+10.70 Units / 40% ROI)
  • The Los Angeles Rams have hit the 3Q Game Total Over in 12 of their last 17 games (+6.05 Units / 28% ROI)
  • The Los Angeles Rams have hit the 2Q Moneyline in 6 of their last 7 games at home (+5.93 Units / 72% ROI)
  • The Los Angeles Rams have covered the 2Q Spread in 6 of their last 7 games at home (+4.80 Units / 60% ROI)
  • The Los Angeles Rams have covered the Spread in 12 of their last 20 games (+3.25 Units / 15% ROI)

Cardinals Against the Spread (ATS) Record

Against the spread this NFL season, the Cardinals art 9-6 (+2.2 Units / 13.1% ROI).

  • Cardinals are 7-8 when betting on the Moneyline for -1.2 Units / -5.96% ROI
  • Cardinals are 7-7 when betting the Over for -0.7 Units / -4.24% ROI
  • Cardinals are 7-7 when betting the Under for -0.7 Units / ROI

Rams Against the Spread (ATS) Record

Against the spread this NFL season, the Rams are 8-7 (+0.35 Units / 2.12% ROI).

  • Rams are 9-6 when betting on the Moneyline for +5 Units / 24.63% ROI
  • Rams are 7-8 when betting the Over for -1.85 Units / -11.18% ROI
  • Rams are 8-7 when betting the Under for +0.3 Units / 1.82% ROI

Arizona Cardinals: Keys to the Game vs. the Los Angeles Rams

The Cardinals were 1-6 (.143) when sacking the QB 3 or more times last season — 2nd-worst in NFL; League Avg: .650.

The Cardinals were winless (0-3) when forcing 2 or more turnovers last season — worst in NFL; League Avg: .707.

The Cardinals were winless (0-5) when allowing 250 or more passing yards last season — T-worst in NFL; League Avg: .414.

The Cardinals were 2-10 (.167) when the opposing team commits less than 60 yards in penalties last season — 2nd-worst in NFL; League Avg: .495.

Los Angeles Rams: Keys to the Game vs. the Arizona Cardinals

The Rams are undefeated (6-0) when within 7 points entering the 4th quarter this season — best in NFL; League Avg: .500.

The Rams are winless (0-5) when losing at least one fumble this season — T-worst in NFL; League Avg: .380.

The Rams are undefeated (5-0) when making 3 or more explosive runs in a game since the 2023 season — T-best in NFL; League Avg: .605.

The Rams are 4-1 (.800) vs top 10 pass offenses this season — 3rd-best in NFL; League Avg: .407.

Additional Matchup Notes for Arizona Cardinals vs. Los Angeles Rams

The Rams have been successful on 56.3% of plays they have run on play action passes this season — 4th-best in NFL. The Cardinals have allowed their opponents to be successful on 56.2% of plays on play action passes this season — T-3rd-worst in NFL.

The Rams have averaged 0.11 epa per play against a light front since the 2023 season — T-4th-best in NFL. The Cardinals have allowed 0.07 epa per play with a light front since the 2023 season — 2nd-worst in NFL.

The Rams have run successful plays on 56.9% of pass attempts on play action passes since the 2023 season — 4th-best in NFL. The Cardinals have allowed successful plays on 57.0% of pass attempts on play action passes since the 2023 season — worst in NFL.

The Cardinals have averaged just -0.40 epa per play against a heavy rush since the 2023 season — worst in NFL. The Rams have allowed just -0.44 epa per play with a heavy rush since the 2023 season — 2nd-best in NFL.

The Cardinals have run successful plays on just 32.2% of pass attempts against a heavy rush since the 2023 season — 2nd-worst in NFL. The Rams have allowed successful plays on just 33.3% of pass attempts with a heavy rush since the 2023 season — T-3rd-best in NFL.

The Cardinals have gone three and out on 16.3% of their drives this season — 5th-best in NFL. The Rams have forced three and outs on 17.1% of opponent drives this season — 5th-worst in NFL.

Arizona Cardinals Offense: Important Stats

The Cardinals had 23 rushes of 20+ yards last season — most in NFL.

The Cardinals went for two on 36% of PATs last season — highest in NFL; League Avg: 10%.

The Cardinals targeted TEs 32% of the time (179 Pass Attempts/555 plays) last season — 2nd-highest in NFL; League Avg: 20%.

The Cardinals have averaged -0.40 epa per play against a heavy rush since the 2023 season — worst in NFL; League Avg: -0.04.

Los Angeles Rams Offense: Important Stats

The Rams have run successful plays on 82% of pass attempts against a light rush this season — best in NFL; League Avg: 44%.

The Rams had an average drive start position from the 46.6 yard line in Week 16 — best in NFL; League Avg: 27.7.

The Rams started 4 drives inside opposing territory in Week 16 — most in NFL.

The Rams went three and out on 6% of their drives in the 1st quarter last season — best in NFL; League Avg: 22%.

Arizona Cardinals Defense: Important Stats

19% of the plays ran against the Cardinals were in the red zone last season — worst in NFL; League Avg: 14%.

The Cardinals defense has allowed successful plays on 48% of plays with a base front since the 2023 season — worst in NFL; League Avg: 43%.

The Cardinals defense has allowed successful plays on 47% of plays since the 2023 season — worst in NFL; League Avg: 42%.

The Cardinals defense has allowed successful plays on 49% of plays in the 1st half since the 2023 season — worst in NFL; League Avg: 43%.

Los Angeles Rams Defense: Important Stats

The Rams defense allowed successful plays on 59% of pass attempts in the 1st quarter last season — worst in NFL; League Avg: 47%.

The Rams defense has allowed opponents to catch just 63 of 128 passes (49% Reception Pct) on 3rd and long since the 2023 season — best in NFL; League Avg: 62%.

The Rams defense has allowed 13 TDs on first drive of the game since the 2023 season — T-most in NFL.

The Rams defense has allowed a passer rating of just 44.9 on 3rd and long (60 Pass Attempts) this season — 2nd-best in NFL; League Avg: 81.6.

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About the Author

Shane Jackson

Read More @Sjacksonmgm

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.

Shane Jackson is a Web Content Writer for BetMGM, covering MLB and NBA. After graduating from the University of Kansas, his previous stops include MLB.com, Lawrence Journal-World, Manhattan Mercury, Bet Chicago Sports, WynnBET, and Sportsbook Review.