- The Chiefs (2-0) are -5.5 point favorites vs the Colts (0-1)
- Total (Over/Under): 51 points
- Watch the game on CBS
The Kansas City Chiefs (2-0) visit Lucas Oil Stadium to take on the Indianapolis Colts (0-1) on Sep. 25. Kickoff is scheduled for 1:00pm EDT in Indianapolis.
The Chiefs are betting favorites in Week 3, with the spread sitting at -5.5 (-110).
The Chiefs vs. Colts Over/Under is 51 total points for the game.
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Chiefs vs. Colts Odds, Spread, Over/Under Week 3
| Spread | Total (O/U) | Moneyline | |
| Kansas City Chiefs | -5.5 -110 | 51 -110 | -250 |
| Indianapolis Colts | +5.5 -110 | 51 -110 | +200 |
Chiefs vs. Colts Prediction for Week 3
Based on recent trends, the winning team model predicts the Chiefs will win this Week 3 game with 69.3% confidence.
Chiefs vs Colts Spread Prediction for Week 3
Based on recent against-the-spread trends, the model predicts the Colts will cover the spread this Week 3 with 55.0% confidence.
Both predictions factor in up-to-date player injuries for both the Chiefs and Colts, plus offensive & defensive matchups, recent games and key player performances this season.
Best Chiefs Player Prop Bets Today
We’ve highlighted some favorite NFL player prop bets for Chiefs players for Week 3, looking at profitable historical betting trends:
Best Colts Player Prop Best Bets Today
And here are some top NFL player prop bets for Colts players for Week 3, looking at profitable historical betting trends:
First Touchdown Scorer Bet for Colts vs Chiefs
| Player Name | 1st TD Odds |
|---|---|
| Jonathan Taylor | +500 |
| Travis Kelce | +650 |
| Clyde Edwards-Helaire | +800 |
| JuJu Smith-Schuster | +1100 |
| Michael Pittman | +1200 |
Anytime Touchdown Scorer Bet for Colts vs Chiefs
| Player Name | Anytime TD Odds |
|---|---|
| Jonathan Taylor | -190 |
| Travis Kelce | -150 |
| Clyde Edwards-Helaire | -105 |
| JuJu Smith-Schuster | +140 |
| Michael Pittman | +160 |
Receiving Props: Total Receiving Yards for Colts vs Chiefs
| Player Name | Over | Under |
|---|---|---|
| Nyheim Hines | 26.5 -115 | 26.5 -115 |
| Jerick McKinnon | 15.5 -115 | 15.5 -110 |
| Marquez Valdes-Scantling | 40.5 -115 | 40.5 -115 |
| Noah Gray | 7.5 -120 | 7.5 -110 |
| Travis Kelce | 71.5 -115 | 71.5 -115 |
Rushing Props: Total Rushing Yards for Colts vs Chiefs
| Player Name | Over | Under |
|---|---|---|
| Matt Ryan | 2.5 -115 | 2.5 -115 |
| Clyde Edwards-Helaire | 46.5 -115 | 46.5 -115 |
| Jerick McKinnon | 14.5 -115 | 14.5 -115 |
| Jonathan Taylor | 87.5 -115 | 87.5 -110 |
| Patrick Mahomes | 11.5 -115 | 11.5 -115 |
Chiefs Betting Trends: ATS, Moneyline, Over/Under
Colts Betting Trends: ATS, Moneyline, Over/Under
Chiefs Against the Spread (ATS) Record
Against the spread this NFL season, the Chiefs have gone 1-1 (-0.1 Units / -4.55% ROI).
- Chiefs are 2-0 when betting on the Moneyline for +2 Units / 43.48% ROI
- Chiefs are 1-1 when betting the Over for -0.1 Units / -4.55% ROI
- Chiefs are 1-1 when betting the Under for -0.1 Units / ROI
Colts Against the Spread (ATS) Record
Against the spread this NFL season, the Colts have gone 0-2 (-2.15 Units / -100% ROI).
- Colts are 0-1 when betting on the Moneyline for -1.6 Units / -32.65% ROI
- Colts are 0-2 when betting the Over for -2.2 Units / -100% ROI
- Colts are 2-0 when betting the Under for +2 Units / 90.91% ROI
Kansas City Chiefs: Keys to the Game vs. the Indianapolis Colts
The Chiefs were 1-2 (.333) when rushing less than 20 times last season — tied for 3rd-best in NFL; League Avg: .121.
The Chiefs are 2-2 (.500) when the opposing team rushes more than 30 times since the 2021 season — tied for best in NFL; League Avg: .172.
The Chiefs were 2-2 (.500) when the opposing team rushes more than 30 times last season — tied for best in NFL; League Avg: .165.
The Chiefs were undefeated (8-0) when allowing less than 22 points last season — tied for best in NFL; League Avg: .762.
Indianapolis Colts: Keys to the Game vs. the Kansas City Chiefs
The Colts were winless (0-2) when rushing less than 20 times last season — tied for worst in NFL; League Avg: .121.
The Colts are winless (0-3) when the opposing team rushes more than 30 times since the 2021 season — tied for worst in NFL; League Avg: .172.
The Colts were 2-4 (.333) when making less than 3 explosive runs in a game last season — tied for 9th-worst in NFL; League Avg: .454.
The Colts were 9-2 (.818) when rushing for 120 or more yards last season — tied for 8th-best in NFL; League Avg: .670.
Additional Matchup Notes for Kansas City Chiefs vs. Indianapolis Colts
The Colts have run successful plays on just 23.8% of pass attempts when their QB was under pressure since the 2021 season — fifth-worst in NFL. The Chiefs have pressured opposing QBs on 28.2% of passing plays since the 2021 season — fourth-best in NFL.
Colts RBs have 48.7 receiving yards per game since the 2020 season — third-best in NFL. The Chiefs have averaged 51.1 receiving yards per game allowed to RBs since the 2020 season — worst in NFL.
The Colts are averaging 5.6 yards per carry on first down since the 2021 season — best in NFL. The Chiefs have allowed 4.9 yards per carry on first down since the 2021 season — third-worst in NFL.
The Chiefs have run successful plays on 58.1% of pass attempts this season — best in NFL. Colts have allowed successful plays on 53.7% of pass attempts this season — fifth-worst in NFL.
The Chiefs have run successful plays on 53.9% of pass attempts since the 2021 season — best in NFL. Colts have allowed successful plays on 50.3% of pass attempts since the 2021 season — tied for second-worst in NFL.
The Chiefs have run successful plays on 60.5% of pass attempts on their opponent’s side of the field this season — second-best in NFL. Colts have allowed successful plays on 60.0% of pass attempts on their own side of the field this season — third-worst in NFL.
Kansas City Chiefs Offense: Important Stats for Week 3
The Chiefs had a third down conversion rate of 71% against the blitz last season — best in NFL; League Avg: 39%.
The Chiefs have a third down conversion rate of 69% against the blitz since the 2021 season — best in NFL; League Avg: 38%.
The Chiefs have scored on 49% of their drives in the 1st quarter since the 2021 season — best in NFL; League Avg: 28%.
The Chiefs converted first downs on 107 of 206 plays (52%) on 3rd down last season — best in NFL; League Avg: 40%.
Indianapolis Colts Offense: Important Stats for Week 3
The Colts did not record a TD in 11 drives in Week 2 — tied for worst Drives Per TD rate in NFL; League Avg: 4.8.
The Colts have run successful plays on 22% of pass attempts in the 3rd quarter this season — tied for worst in NFL; League Avg: 48%.
The Colts ran successful plays on 27% of plays in Week 2 — worst in NFL; League Avg: 43%.
The Colts have scored on 17% of their drives this season — worst in NFL; League Avg: 34%.
Kansas City Chiefs Defense: Important Stats for Week 3
The Chiefs defense allowed successful plays on 56% of rush attempts in the 4th quarter last season — worst in NFL; League Avg: 42%.
The Chiefs defense has pressured opposing QBs 32 times this season — most in NFL.
The Chiefs defense has allowed 9.5 receptions per game (19/2) to RBs this season — worst in NFL; League Avg: 4.9.
The Chiefs defense sacked opposing QBs on just 5% of pass attempts (31/640) last season — 3rd-worst in NFL; League Avg: 6%.
Indianapolis Colts Defense: Important Stats for Week 3
The Colts defense has allowed successful plays on 8% of plays in the 4th quarter this season — best in NFL; League Avg: 42%.
The Colts defense has not allowed a successful play on any pass attempt in the 4th quarter this season — best in NFL; League Avg: 44%.
The Colts defense has not allowed a successful play on any pass attempt in close and late situations this season — best in NFL; League Avg: 45%.
The Colts defense has allowed a Completion Pct of just 17% (1 completions/6 attempts) in close and late situations this season — best in NFL; League Avg: 60%.
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