NFC West Odds & Winner Prediction 2026

Los Angeles Rams head coach Sean McVay talks with quarterback Matthew Stafford (9) against the San Francisco 49ers during the NFL NFC Championship game, Sunday, Jan. 30, 2022 in Inglewood, Calif. The Rams defeated the 49ers 20-17. (AP Photo/Doug Benc)
(AP Photo/Doug Benc)
Betting Promos This Weekend

Below, bettors can find NFL odds for the NFC West division winner and my NFC West prediction. 

NFC West Odds 2026

Name Odds
San Francisco 49ers-295
Los Angeles Rams+400
Seattle Seahawks+650
Arizona Cardinals+20000

NFC West Prediction 2026

Based on an easier-than-perceived schedule of unique opponents and an improved defense, I predict the Los Angeles Rams (+145) will win the NFC West.

Truthfully, I believe potential flaws exist with all of the Rams, Seahawks and 49ers.

If Arizona is actually going to try to win games next year, don’t be surprised if they come through as NFC West winners.

Additional Analysis: Cardinals Over Under Wins

I lack confidence in the Rams at this price when regression indicators exist. So much went right for Los Angeles last year offensively on their way to a +30.8% DVOA percentage.

Most of that success came in the latter half of the season. It coincided with the Rams playing bad or hurt defenses almost exclusively.

An old quarterback, injury-prone WR1 and aging WR2 are not good trends for trusting LA as favorites. Bettors also shouldn’t ignore Rob Havenstein’s retirement along the offensive line.

I’m simultaneously required to mention that positive regression indicators exist.

The team finished 4-5 in one-possession games last year and dropped two divisional games it probably should have won.

Kyren Williams fumbled at the goal line against San Francisco, while Seattle required divine intervention to win at home. The same is true of Rams-Eagles in Week 3.

This offseason, Los Angeles radically improved the defense. Trent McDuffie and Jaylen Watson directly address the Rams’ biggest weakness.

On paper, the schedule looks daunting. By 2026 NFL Strength of Schedule, the Rams project to face the league’s fourth-hardest schedule by season win totals.

Unique games against the Packers, Bucs and Bills may play easier than expected, however.

If that’s the case, it gives the Rams a chance to overcome the schedule advantage vs. San Francisco. Next year, San Francisco’s unique opponents own a 20.5 combined win total.

By contrast, the Rams’ unique games come against teams owning a 29.5 combined total. If the defense takes a step forward, it may help offset the likely offensive regression.

Those factors lead me to the Rams as the NFC West winner.

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About the Author Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.