Brentford vs. Southampton Prediction, Odds & Match Preview

Brentford's Bryan Mbeumo runs into position during the English Premier League soccer match between Brentford and Crystal Palace, at the Gtech Community Stadium in London, Sunday, Aug. 18, 2024.
(AP Photo/Dave Shopland)
  • Brentford is predicted to be a -0.5-goal favorite against Southampton.
  • Brentford has won three straight meetings against Southampton.
  • I predict the likeliest outcome is a Brentford victory.

Brentford will look to capture their second home win of the season on Saturday as they welcome Southampton to London.ย 

Both teams enter this match off Matchday 2 defeats. Southampton fell 1-0 as home favorites to Nottingham Forest, while Brentford lost 2-0 at Liverpool.ย 

The good news for Brentford? Theyโ€™ve historically dominated this series, winning three straight meetings.ย 

Hereโ€™s a look at the Premier League odds and my prediction for Saturdayโ€™s fixture.ย 

Brentford vs. Southampton Odds, Premier League

  • Brentford Moneyline: -135
  • Southampton Moneyline: +340
  • Draw Moneyline: +290
  • Over/Under: 2.5 Goals (-155/+110)
  • Both Teams to Score: Yes (-155), No (+110)

Brentford vs. Southampton Prediction: Game Spread

If forced to make a prediction, I would back the Brentford moneyline (-135). However, itโ€™s strictly a lean for me as this feels like a trap.ย 

I can make a case for both sides but with caveats attached to each that lead me to other bets on the board.ย 

The case for Brentford is stronger.ย 

The Bees have historically dominated Southampton. Over the last three meetings, Thomas Frankโ€™s team owns a +8 goal differential and a +6.86 expected goal differential.ย 

Thereโ€™s also a historically profitable system supporting a bet on the hosts.ย 

Since 2012, favorites priced between -199 and +106 are 68.5% SU when both teams lost their last game, and the favorite posted between a +0 and +4 margin in the last head-to-head.ย 

When those teams failed to score in their last game, they improve to 70% SU, including 73% at home.ย 

The issue? Itโ€™s generally better fading teams that closed as underdogs in their last game. That designation doesnโ€™t fit Southampton.ย 

Visitors Southampton also fit a historically profitable system outlined in my EPL predictions. However, it also comes with a caveat.ย 

The system generally works better with road underdogs. However, those road underdogs produce a higher return on investment against home teams off results.ย 

In fact, the ROI percentage of visiting underdogs against teams off a loss between one and three goals is only 2.2%.ย 

Based on conflicting reports, this match is an easy pass with a slight lean to Brentford.ย 

Brentford Record, Last 5 Matches

  • Aug. 25 at Liverpool: 0-2, L
  • Aug. 17 vs. Crystal Palace: 2-1, W
  • Aug. 9 vs. Wolfsburg: 4-4, D (Friendly)
  • Aug. 3 at Watford: 1-1, D (Friendly)
  • July 25 at Benfica: 1-1, D (Friendly)

Southampton Record, Last 5 Matches

  • Aug. 24 vs. Nottingham Forest: 0-1, L
  • Aug. 17 at Newcastle United: 0-1, L
  • Aug. 10 vs. Getafe: 0-0, D (Friendly)
  • Aug. 7 vs. Lazio: 1-1, D (Friendly)
  • Aug. 3 at Millwall: 1-0, W (Friendly)

Visit the BetMGM online sportsbook for the latest Brentford odds and Southampton odds!

EPL Match Schedule This Weekend

HomeAwayDateTime (ET)Location
Nottingham ForestChelseaMay. 2511 a.m.The City Ground
SouthamptonArsenalMay. 2511 a.m.St. Mary's Stadium
LiverpoolCrystal PalaceMay. 2511 a.m.Anfield
Ipswich TownWest HamMay. 2511 a.m.Portman Road
BournemouthLeicester CityMay. 2511 a.m.Vitality Stadium
Man UnitedAston VillaMay. 2511 a.m.Old Trafford
NewcastleEvertonMay. 2511 a.m.St. James' Park
TottenhamBrightonMay. 2511 a.m.Tottenham Hotspur Stadium
WolvesBrentfordMay. 2511 a.m.Molineux
FulhamManchester CityMay. 2511 a.m.Craven Cottage

EPL Standings

TeamRecord (Wins-Draws-Losses)PointsGoal Differential
Liverpool25-8-48345
Arsenal19-14-47134
Manchester City20-8-96826
Newcastle United20-6-116622
Chelsea19-9-96620
Aston Villa19-9-9669
Nottingham Forest19-8-106513
Brighton15-14-8584
Brentford16-7-14559
Fulham15-9-13542
Bournemouth14-11-12539
Crystal Palace13-13-11520
Everton10-15-1245-3
Wolves12-5-2041-15
West Ham10-10-1740-18
Manchester United10-9-1839-12
Tottenham11-5-21382
Leicester City6-7-2425-45
Ipswich Town4-10-2322-44
Southampton2-6-2912-59

EPL ATS Records

TeamATS RecordATS%Home ATS RecordHome ATS%Road ATS RecordRoad ATS%
Arsenal14-17-645.9%5-10-436.8%9-7-255.6%
Aston Villa18-18-150.0%9-9-150.0%9-9-050.0%
Bournemouth19-16-254.1%8-10-044.4%11-6-263.2%
Brentford22-12-363.5%11-8-057.9%11-4-369.4%
Brighton & Hove Albion21-15-158.1%10-9-052.6%11-6-163.9%
Chelsea13-20-440.5%7-9-344.7%6-11-136.1%
Crystal Palace20-13-459.5%8-7-452.6%12-6-066.7%
Everton19-12-659.5%9-8-252.6%10-4-466.7%
Fulham18-14-455.6%8-10-044.4%10-5-463.2%
Ipswich Town14-20-341.9%4-13-125.0%10-7-257.9%
Leicester City18-18-150.0%8-11-042.1%10-7-158.3%
Liverpool16-19-245.9%7-9-244.4%9-10-047.4%
Manchester City13-24-035.1%7-12-036.8%6-12-033.3%
Manchester United14-18-544.6%7-9-244.4%7-9-344.7%
Newcastle United21-15-158.1%13-5-072.2%8-10-144.7%
Nottingham Forest23-14-062.2%10-8-055.6%13-6-068.4%
Southampton13-20-440.5%4-12-227.8%9-8-252.6%
Tottenham Hotspur13-23-136.5%6-11-136.1%7-12-036.8%
West Ham United18-17-251.4%6-12-134.2%12-6-066.7%
Wolverhampton Wanderers19-15-355.4%8-8-250.0%11-7-160.5%
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About the Author

Nick Hennion

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Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.