Southampton vs. Manchester United Prediction, Odds & Preview

  • Southampton is predicted to be a +0.5-goal underdog against Manchester United.
  • Manchester United has won 13 of their last 14 against promoted teams.
  • I predict Manchester United earn all three points at St. Maryโ€™s Stadium.

Seeking an end to their two-match losing streak, Manchester United travel to face Southampton.ย 

Prior to the international break, the Red Devils lost 3-0 at home to Liverpool, their second straight defeat following a road loss to Brighton.ย 

Southampton has yet to earn points this season. In their last match, they traveled to Brentford and received a 3-1 thumping.ย 

Hereโ€™s a look at the Premier League odds and my prediction for this fixture.ย 

Southampton vs. Manchester United Odds, Premier League

  • Southampton Moneyline: +333
  • Manchester United Moneyline: -135
  • Draw Moneyline: +290
  • Over/Under: 2.5 Goals (-160/+115)
  • Both Teams to Score: Yes (-160), No (+110)

Southampton vs. Manchester United Prediction: Moneyline

My prediction for Saturdayโ€™s Southampton vs. Manchester United fixture is the Manchester United Moneyline (-135).ย 

I hate that I have to make this bet. I canโ€™t even remember the last time I put real dollars on Manchester United.ย 

But thereโ€™s evidence supporting a bet on the Red Devils, who have won 13 of their last 14 against promoted teams.ย 

United has lost two straight, yes, but they thoroughly dominated the opening match against Fulham.ย 

Erik ten Hagโ€™s squad only won the match 1-0. However, expected goals finished 2.4 to 0.4 in favor of the hosts.ย 

Even if you discount the Alejandro Garnacho attempt worth 0.67 xG and zero psxG in the 94th minute, United won the psxG battle 2.1 to 0.9, per fbref.com.ย 

Plus, Southampton has actually run lucky in their last two matches. The Saints posted a -3 goal differential compared to a -4.1 psxGDiff against Nottingham Forest and Brentford.ย 

Two systems also suggest United is worth a bet.ย 

First, early moneyline moves on favorites tend to signal the correct side. Since 2012, favorites in games 1-9 that see their moneyline rise are 67.5% SU, assuming two factors:

  • The previous head-to-head result was either +0 or +1
  • The underdogโ€™s previous game margin fell between -8 and -1

When those favorites are coming off a loss, theyโ€™re 19-5 SU (79.2%), including 11-2 SU (84.6%) off a multi-goal defeat.ย 

The other system suggests fading previous dogs early.ย 

Since 2012, favorites priced between -205 and -105 in games 2-10 are 78% SU, assuming three factors:

  • The underdogโ€™s previous game margin fell between -4 and +0
  • The underdog was an underdog in their previous game
  • The previous head-to-head result fell between +0 and +4

When those favorites are playing off a loss, theyโ€™re 24-7 SU and have dropped all three points only four times.ย 

Based on those outlays, lay the juice with United off an extended rest period.ย 

Southampton Record, Last 5 Matches

  • Aug. 31 at Brentford: 1-3, L
  • Aug. 28 at Cardiff City: 5-3, W (EFL Cup)
  • Aug. 24 vs. Nottingham Forest: 0-1, L
  • Aug. 17 at Newcastle United: 0-1, L
  • Aug. 10 vs. Getafe: 0-0, D (Friendly)

Manchester United Record, Last 5 Matches

  • Sept. 1 vs. Liverpool: 0-3, L
  • Aug. 24 at Brighton: 1-2, L
  • Aug. 16 vs. Fulham: 1-0, W
  • Aug. 10 vs. Man City: 1-1, D (City Win on PKโ€™s)
  • Aug. 3 vs. Liverpool: 0-3, L (Friendly)

Visit the BetMGM online sportsbook for the latest Southampton odds and Manchester United odds!

EPL Match Schedule This Weekend

HomeAwayDateTime (ET)Location
Nottingham ForestChelseaMay. 2511 a.m.The City Ground
SouthamptonArsenalMay. 2511 a.m.St. Mary's Stadium
LiverpoolCrystal PalaceMay. 2511 a.m.Anfield
Ipswich TownWest HamMay. 2511 a.m.Portman Road
BournemouthLeicester CityMay. 2511 a.m.Vitality Stadium
Man UnitedAston VillaMay. 2511 a.m.Old Trafford
NewcastleEvertonMay. 2511 a.m.St. James' Park
TottenhamBrightonMay. 2511 a.m.Tottenham Hotspur Stadium
WolvesBrentfordMay. 2511 a.m.Molineux
FulhamManchester CityMay. 2511 a.m.Craven Cottage

EPL Standings

TeamRecord (Wins-Draws-Losses)PointsGoal Differential
Liverpool25-8-48345
Arsenal19-14-47134
Manchester City20-8-96826
Newcastle United20-6-116622
Chelsea19-9-96620
Aston Villa19-9-9669
Nottingham Forest19-8-106513
Brighton15-14-8584
Brentford16-7-14559
Fulham15-9-13542
Bournemouth14-11-12539
Crystal Palace13-13-11520
Everton10-15-1245-3
Wolves12-5-2041-15
West Ham10-10-1740-18
Manchester United10-9-1839-12
Tottenham11-5-21382
Leicester City6-7-2425-45
Ipswich Town4-10-2322-44
Southampton2-6-2912-59

EPL ATS Records

TeamATS RecordATS%Home ATS RecordHome ATS%Road ATS RecordRoad ATS%
Arsenal14-17-645.9%5-10-436.8%9-7-255.6%
Aston Villa18-18-150.0%9-9-150.0%9-9-050.0%
Bournemouth19-16-254.1%8-10-044.4%11-6-263.2%
Brentford22-12-363.5%11-8-057.9%11-4-369.4%
Brighton & Hove Albion21-15-158.1%10-9-052.6%11-6-163.9%
Chelsea13-20-440.5%7-9-344.7%6-11-136.1%
Crystal Palace20-13-459.5%8-7-452.6%12-6-066.7%
Everton19-12-659.5%9-8-252.6%10-4-466.7%
Fulham18-14-455.6%8-10-044.4%10-5-463.2%
Ipswich Town14-20-341.9%4-13-125.0%10-7-257.9%
Leicester City18-18-150.0%8-11-042.1%10-7-158.3%
Liverpool16-19-245.9%7-9-244.4%9-10-047.4%
Manchester City13-24-035.1%7-12-036.8%6-12-033.3%
Manchester United14-18-544.6%7-9-244.4%7-9-344.7%
Newcastle United21-15-158.1%13-5-072.2%8-10-144.7%
Nottingham Forest23-14-062.2%10-8-055.6%13-6-068.4%
Southampton13-20-440.5%4-12-227.8%9-8-252.6%
Tottenham Hotspur13-23-136.5%6-11-136.1%7-12-036.8%
West Ham United18-17-251.4%6-12-134.2%12-6-066.7%
Wolverhampton Wanderers19-15-355.4%8-8-250.0%11-7-160.5%
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About the Author

Nick Hennion

Read More @nickhennion

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.

Nick Hennion is a senior content writer for BetMGM. His previous stops include VSiN, NBC Sports, The Action Network and Forbes Betting. He owns a bachelor's degree from Syracuse University and a master's degree from Northwestern University.