White Sox vs Padres Prediction, Odds & Player Prop Bets Today – MLB, Sep 22

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MLB betting odds, predictions and betting odds for today's games
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BetMGM Betting @BETMGM Sep 22, 2024, 11:00 AM
  • The Padres are -350 favorites vs the White Sox
  • White Sox vs Padres Over / Under today: 7.5 Runs
  • White Sox / Padres TV Channel: NSCH | PDTV

The Chicago White Sox (+260) visit Petco Park to take on the San Diego Padres (-350) on Sunday, September 22, 2024. First pitch is scheduled for 4:10pm EDT in San Diego, CA.

This season, the White Sox are against the spread (ATS), while the Padres are ATS.

White Sox vs Padres Starting Pitchers Today:

  • White Sox starting pitcher: Sean Burke 1-0, 2.25 ERA
  • Padres starting pitcher: Yu Darvish 6-3, 3.23 ERA

White Sox vs. Padres Odds, Run Line, Over/Under & Moneyline

SpreadOver / UnderMoneyline
White Sox+2.5 -130O 8 -105+260
Padres -2.5 +110U 8 -115-350

White Sox vs Padres Prediction for Today’s Game

Based on recent trends the model predicts the Padres will win Sunday‘s MLB game with 69.4% confidence, factoring in game simulations, recent player performances, starting pitchers and injuries.


Bet now on White Sox vs Padres and all games with BetMGM


We’ve highlighted some favorite MLB player prop bets for White Sox players for Sunday‘s game, looking at profitable historical betting trends:

Best White Sox Player Prop Bets Today:

  • Andrew Benintendi has hit the Home Runs Over in 5 of his last 19 away games (+22.20 Units / 117% ROI)
  • Lenyn Sosa has hit the Total Bases Over in 10 of his last 12 away games (+10.20 Units / 65% ROI)
  • Lenyn Sosa has hit the Singles Over in 18 of his last 25 games (+9.45 Units / 31% ROI)
  • Lenyn Sosa has hit the Hits Runs and RBIs Over in 17 of his last 26 games (+8.45 Units / 30% ROI)
  • Lenyn Sosa has hit the Hits Over in 20 of his last 26 games (+7.80 Units / 14% ROI)

And here are some favorite MLB player prop bets for Padres players for Sunday‘s game, looking at profitable historical betting trends:

Best Padres Player Prop Best Bets Today:

  • Jackson Merrill has hit the Home Runs Over in 11 of his last 45 games (+32.50 Units / 72% ROI)
  • Jackson Merrill has hit the Total Bases Over in 31 of his last 50 games (+17.15 Units / 32% ROI)
  • Manny Machado has hit the RBIs Over in 27 of his last 48 games (+15.80 Units / 32% ROI)
  • Luis Arraez has hit the Singles Over in 22 of his last 26 games (+14.10 Units / 26% ROI)
  • Fernando Tatis Jr. has hit the Hits Over in 11 of his last 13 games (+12.15 Units / 55% ROI)
  • The Chicago White Sox have hit the Team Total Under in 22 of their last 32 away games (+11.10 Units / 30% ROI)
  • The Chicago White Sox have hit the Game Total Under in 17 of their last 29 away games (+7.25 Units / 23% ROI)
  • The Chicago White Sox have covered the Run Line in 5 of their last 6 games (+3.45 Units / 44% ROI)
  • The Chicago White Sox have hit the 1st Five Innings (F5) Team Total Under in 4 of their last 5 away games (+3.05 Units / 50% ROI)
  • The Chicago White Sox have covered the 1st Five Innings (F5) Run Line in 5 of their last 8 away games (+2.20 Units / 25% ROI)
  • The San Diego Padres have hit the Moneyline in 51 of their last 77 games (+18.30 Units / 17% ROI)
  • The San Diego Padres have hit the Game Total Over in 43 of their last 76 games (+9.10 Units / 11% ROI)
  • The San Diego Padres have covered the Run Line in 63 of their last 122 games (+6.17 Units / 4% ROI)
  • The San Diego Padres have hit the 1st Five Innings (F5) Team Total Under in 20 of their last 32 games at home (+6.05 Units / 15% ROI)
  • The San Diego Padres have hit the Team Total Under in 10 of their last 15 games at home (+4.10 Units / 23% ROI)

White Sox Against the Spread (ATS) Record

Against the spread this season, the White Sox are against the Run Line ( Units / ROI).

  • away moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • away total over record when betting on the total runs Over for over units Units / over ROI ROI
  • away total under record when betting on the total runs Under for under units Units / under ROI ROI

Padres Against the Spread (ATS) Record

Against the spread this season, the Padres are against the Run Line ( Units / ROI).

  • home moneyline record when betting on the Moneyline for ML units Units / ML ROI ROI
  • home total over record when betting on the total runs Over for over units Units / over ROI ROI
  • home total under record when betting on the total runs Under for under units Units / under ROI ROI

Padres vs White Sox Home Run Prop Bets Today

Over Under
Fernando Tatis Jr. (SD) 0.5 +340 0.5 -450
Manny Machado (SD) 0.5 +400 0.5 -550
Jackson Merrill (SD) 0.5 +425 0.5 -600
Luis Robert (CWS) 0.5 +500 0.5 -750
Jurickson Profar (SD) 0.5 +575 0.5 -800

Padres vs White Sox Total Hits Prop Bets Today

Over Under
Jackson Merrill (SD) 0.5 -275 0.5 +200
Manny Machado (SD) 0.5 -250 0.5 +190
Dominic Fletcher (CWS) 0.5 -200 0.5 +150
Xander Bogaerts (SD) 0.5 -190 0.5 +145
Lenyn Sosa (CWS) 0.5 -190 0.5 +140

Padres vs White Sox RBI Prop Bets Today

Over Under
Manny Machado (SD) 0.5 +130 0.5 -165
Jackson Merrill (SD) 0.5 +140 0.5 -185
Fernando Tatis Jr. (SD) 0.5 +150 0.5 -200
Jurickson Profar (SD) 0.5 +185 0.5 -250
Xander Bogaerts (SD) 0.5 +190 0.5 -250

Padres vs White Sox Strikeout Prop Bets Today

Over Under
Yu Darvish (SD) 5.5 -150 5.5 +115

Sean Burke has thrown breaking pitches 62% of the time (66/106) vs left-handed batters this month (2 games) — highest in MLB among starting pitchers with at least 6 total IP; League Avg: 28% — 100th Percentile.

Sean Burke has not induced opposing hitters to ground into a double play in 3 opportunities (0%) this month (2 games) — tied for lowest in MLB among starting pitchers with at least 6 total IP; League Avg: 10% — 23rd Percentile.

Sean Burke has thrown off-speed pitches 64% of the time (68/106) vs left-handed batters this month (2 games) — 4th highest in MLB among starting pitchers with at least 6 total NonFB; League Avg: 45% — 97th Percentile.

Sean Burke has thrown off-speed pitches 64% of the time (88/138) this month (2 games) — 2nd highest in MLB among starting pitchers with at least 6 total NonFB; League Avg: 44% — 99th Percentile.

Padres Starting Pitcher Stats & Trends

Yu Darvish has thrown breaking pitches 57% of the time (371/656) when behind in the count since last season — 2nd highest in MLB among starting pitchers with at least 126 total IP; League Avg: 23% — 99th Percentile.

Yu Darvish has thrown his slider 50% of the time (326/656) when he’s behind in the count since last season — highest in MLB among starting pitchers with at least 126 total SL; League Avg: 18% — 100th Percentile.

Yu Darvish has a strike rate of 73% (290/398) on sliders this season — highest in MLB among starting pitchers with at least 61 total IP; League Avg: 63% — 100th Percentile.

Opponents are hitting just .146 (28-for-192) against Yu Darvish on fastballs away since the 2022 season — 2nd best in MLB among starting pitchers with at least 191 total IP; League Avg: .240 — 99th Percentile.

White Sox Keys to the Game vs. the Padres

The White Sox are just 73-36 (.670) when leading entering the 7th inning since the 2023 season — lowest in MLB; League Avg: .858.

The White Sox are just 14-46 (.233) after a road loss this season — lowest in MLB; League Avg: .485.

The White Sox are just 28-22 (.560) when leading entering the 7th inning this season — lowest in MLB; League Avg: .857.

The White Sox are just 79-74 (.516) when allowing 4 or fewer runs since the 2023 season — lowest in MLB; League Avg: .729.

Padres Keys to the Game vs. the White Sox

The Padres are 51-35 (.593) after a win this season — best in MLB; League Avg: .492.

The Padres are 17-11 (.607) after a road loss this season — 2nd best in MLB; League Avg: .485.

The Padres are 27-19 (.587) after a road win this season — 3rd best in MLB; League Avg: .464.

The Padres are 10-56 (.152) when trailing entering the 8th inning this season — 4th best in MLB; League Avg: .099.

The White Sox have a winning percentage of just 26% at home this season — lowest in MLB; League Avg: 52%.

White Sox hitters have an OBP of just .283 (8,789 PA’s) against RHP since last season — lowest in MLB; League Avg: .316.

White Sox hitters have an OBP of just .285 (11,594 PA’s) since last season — lowest in MLB; League Avg: .316.

The White Sox have a winning percentage of just 21% on the road this season — lowest in MLB; League Avg: 48%.

Padres hitters have just 273 strikeouts in 1,571 PA’s (17%) against LHP this season — best in MLB; League Avg: 23%.

The Padres are batting .279 on the road this season — best in MLB; League Avg: .242.

Padres hitters have just 751 strikeouts in 4,284 PA’s (17%) against RHP this season — best in MLB; League Avg: 23%.

Padres hitters have just 1,024 strikeouts in 5,855 PA’s (17%) this season — best in MLB; League Avg: 23%.

The White Sox have won just 10% of games in which their opponents scored first this season — lowest in MLB; League Avg: 31%.

The White Sox have won just 17% of games in which their opponents scored first since last season — lowest in MLB; League Avg: 33%.

White Sox pitchers have won only 6% of games in which they have allowed their opponent to score in three different innings this season — lowest in MLB; League Avg: 26%.

In games when their opponents have scored three or more runs in an inning, the White Sox have won just just 3% of the time this season — lowest in MLB; League Avg: 24%.

The Padres pitchers allowed an average Exit Velocity of just 87.9 MPH in the 2023 season (3,922 balls in play) — best in MLB; League Avg: 89.0

Padres pitchers allowed an average Exit Velocity of 87.9 MPH (3,922 batted balls) in the 2023 season — best in MLB; League Avg: 89.0.

Opponents have a groundball batting average of just .162 against Padres pitchers this month (17 games) — best in MLB; League Avg: .251.

Padres pitchers have a strikeout rate of 24% this season — tied for 4th best in MLB; League Avg: 23%.

Padres vs. White Sox Injuries Tonight That May Affect Prop Bets 

  • San Diego Padres – No Injuries Reported
  • Chicago White Sox – No Injuries Reported

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Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.

Our BetMGM betting authors are experts who focus on individual game matchups & player prop bets with an emphasis on betting odds, lines & predictions.