- The 49ers are -3.5 point favorites vs the Seahawks
- Total (Over/Under): 49 points
- Watch this game on Amazon
The San Francisco 49ers (2-3-0) visit Lumen Field to take on the Seattle Seahawks (3-2-0) on Oct. 10. Kickoff is scheduled for 8:15pm EDT in Seattle, WA.
The 49ers are betting favorites in this matchup, with the spread sitting at -3.5 (-110).
The 49ers vs. Seahawks Over/Under is 49 total points for the game.
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49ers vs. Seahawks Odds, Spread, Over/Under
| Spread | Total (O/U) | Moneyline | |
| 49ers | -3.5 -110 | 49 -110 | -190 |
| Seahawks | +3.5 -110 | 49 -110 | +155 |
49ers vs. Seahawks Prediction
The winning team model predicts the 49ers will win this game with 60.5% confidence, based on game simulations, player injuries, offensive & defensive matchups and recent game results.
49ers vs Seahawks Spread Prediction
Based on recent against-the-spread trends, the model predicts the Seahawks will cover the spread with 52.0% confidence.
This prediction against the spread factors in ATS performances for both teams, opening and current betting lines plus public and sharp money already wagered on this matchup.
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We’ve highlighted some favorite NFL player prop bets for 49ers players this playoff game, looking at profitable historical betting trends:
Best 49ers Player Prop Bets Today
- Christian McCaffrey has hit the Rushing Yards Over in 9 of his last 10 games (+7.85 Units / 67% ROI)
- George Kittle has hit the Longest Reception Over in 10 of his last 12 games (+7.60 Units / 54% ROI)
- Christian McCaffrey has hit the Longest Rush Over in 9 of his last 11 games (+6.75 Units / 53% ROI)
- Christian McCaffrey has hit the Carries Under in 10 of his last 13 games (+6.00 Units / 34% ROI)
- Kyle Juszczyk has hit the Receiving Yards Over in 7 of his last 8 games (+5.70 Units / 62% ROI)
And here are some top NFL player prop bets for Seahawks players for this matchup, looking at profitable historical betting trends:
Best Seahawks Player Prop Best Bets Today
- Sam Howell has hit the Interceptions Over in 10 of his last 11 games (+8.40 Units / 50% ROI)
- DK Metcalf has hit the Longest Reception Over in 10 of his last 12 games (+7.70 Units / 55% ROI)
- Tyler Lockett has hit the Longest Reception Under in his last 6 games at home (+6.00 Units / 75% ROI)
- Jason Myers has hit the Field Goals Over in 12 of his last 18 games (+5.70 Units / 28% ROI)
- Jaxon Smith-Njigba has hit the Longest Reception Over in 9 of his last 13 games (+5.15 Units / 38% ROI)
First Touchdown Scorer Bet for Seahawks vs 49ers
| Player Name | 1st TD Odds |
|---|---|
| Jordan Mason (SF) | +400 |
| Kenneth Walker III (Sea) | +500 |
| Deebo Samuel (SF) | +850 |
Anytime Touchdown Scorer Bet for Seahawks vs 49ers
| Player Name | Anytime TD Odds |
|---|---|
| Jordan Mason (SF) | -175 |
| Kenneth Walker III (Sea) | -120 |
| Deebo Samuel (SF) | +120 |
| DK Metcalf (Sea) | +140 |
Receiving Props: Total Receiving Yards for Seahawks vs 49ers
| Player Name | Over | Under |
|---|---|---|
| George Kittle (SF) | 47.5 -115 | 47.5 -120 |
| DK Metcalf (SEA) | 63.5 -115 | 63.5 -115 |
| Brandon Aiyuk (SF) | 64.5 -120 | 64.5 -110 |
| Deebo Samuel (SF) | 52.5 -120 | 52.5 -110 |
| Tyler Lockett (SEA) | 45.5 -115 | 45.5 -115 |
Rushing Props: Total Rushing Yards for Seahawks vs 49ers
| Player Name | Over | Under |
|---|---|---|
| Brock Purdy (SF) | 12.5 -110 | 12.5 -120 |
| Deebo Samuel (SF) | 13.5 -120 | 13.5 -110 |
49ers Best Bets:
- The San Francisco 49ers have hit the 3Q Game Total Over in 14 of their last 19 games (+8.05 Units / 35% ROI)
- The San Francisco 49ers have covered the 1Q Spread in 8 of their last 11 away games (+5.15 Units / 42% ROI)
- The San Francisco 49ers have hit the 4Q Game Total Under in 12 of their last 19 games (+3.80 Units / 17% ROI)
- The San Francisco 49ers have hit the 1Q Game Total Over in 7 of their last 11 away games (+3.65 Units / 29% ROI)
- The San Francisco 49ers have hit the 1H Moneyline in 8 of their last 11 away games (+3.25 Units / 12% ROI)
Seahawks Best Bets:
- The Seattle Seahawks have hit the 2H Moneyline in 5 of their last 6 games at home (+4.10 Units / 43% ROI)
- The Seattle Seahawks have scored last in 5 of their last 6 games at home (+4.00 Units / 51% ROI)
- The Seattle Seahawks have hit the Game Total Over in 7 of their last 10 games at home (+3.70 Units / 34% ROI)
- The Seattle Seahawks have covered the 3Q Spread in 10 of their last 17 games (+2.80 Units / 14% ROI)
- The Seattle Seahawks have hit the 1Q Moneyline in 9 of their last 21 games (+2.75 Units / 9% ROI)
49ers Against the Spread (ATS) Record
Against the spread this NFL season, the 49ers art 2-3 (-1.2 Units / -22.22% ROI).
- 49ers are 2-3 when betting on the Moneyline for -6.2 Units / -38.75% ROI
- 49ers are 3-2 when betting the Over for +0.8 Units / 14.55% ROI
- 49ers are 2-3 when betting the Under for -1.3 Units / ROI
Seahawks Against the Spread (ATS) Record
Against the spread this NFL season, the Seahawks are 1-3 (-2.3 Units / -41.82% ROI).
- Seahawks are 3-2 when betting on the Moneyline for -1.1 Units / -10.48% ROI
- Seahawks are 4-1 when betting the Over for +2.9 Units / 52.73% ROI
- Seahawks are 1-4 when betting the Under for -3.4 Units / -61.82% ROI
San Francisco 49ers: Keys to the Game vs. the Seattle Seahawks
The 49ers are winless (0-5) when within 7 points at the two minute warning since the 2023 season — worst in NFL; League Avg: .500.
The 49ers were winless (0-3) when within 7 points at the two minute warning last season — worst in NFL; League Avg: .500.
The 49ers are 13-3 (.812) when rushing for 120 or more yards since the 2023 season — 6th-best in NFL. The Seahawks have allowed an average of 136.7 rushing yards per game since the 2023 season — 2nd-worst in NFL.
The 49ers are 9-3 (.750) when possessing the ball longer than their opponent since the 2023 season — T-9th-best in NFL. The Seahawks has allowed an average time of possession of 32 min and 27 s since the 2023 season — T-highest in NFL.
Seattle Seahawks: Keys to the Game vs. the San Francisco 49ers
The Seahawks were 4-1 (.800) when averaging more than 5 yards per rush last season — T-5th-best in NFL; League Avg: .607.
The Seahawks are undefeated (4-0) vs bottom 10 run defenses since the 2023 season — T-best in NFL; League Avg: .581.
The Seahawks were 1-4 (.200) when allowing 3 or more sacks last season — 7th-worst in NFL; League Avg: .350.
The Seahawks were 2-8 (.200) when rushing for less than 100 yards last season — 6th-worst in NFL; League Avg: .336.
Additional Matchup Notes for San Francisco 49ers vs. Seattle Seahawks
The Seahawks ran successful plays on 61.3% of pass attempts against a base front last week — 2nd-best in NFL. The 49ers pressured opposing QBs on 4.2% of pass attempts with a base front last week — 4th-worst in NFL.
The Seahawks ran successful plays on 59.5% of pass attempts against a base rush last week — 4th-best in NFL. The 49ers pressured opposing QBs on 10.7% of pass attempts with a base rush last week — 3rd-worst in NFL.
The Seahawks have gone three and out on 5.6% of their drives in the fourth quarter this season — 5th-best in NFL. The 49ers have forced three and outs on 0% of opponent drives in the 4th quarter this season — T-worst in NFL.
The 49ers have a third down conversion rate of 47.1% since the 2023 season — 2nd-best in NFL. The Seahawks defense has allowed a third down conversion rate of 43.0% since the 2023 season — 3rd-worst in NFL.
The 49ers have run 18.7% offensive plays in the red zone since the 2023 season — best in NFL. The Seahawks have allowed their opponent to run 16.0% of plays in the red zone since the 2023 season — 3rd-worst in NFL.
The 49ers have run 20.7% offensive plays in the red zone this season — best in NFL. The Seahawks have allowed their opponent to run 19.2% of plays in the red zone this season — 4th-worst in NFL.
San Francisco 49ers Offense: Important Stats
The 49ers have targeted RBs 5% of the time (8 Pass Attempts/157 plays) this season — lowest in NFL; League Avg: 17%.
The 49ers ran successful plays on 53% of rush attempts against a base front last season — best in NFL; League Avg: 41%.
The 49ers have completed passes for 20+ yards on 95 of their 648 total passing attempts (15%) since the 2023 season — best in NFL; League Avg: 9%.
The 49ers averaged 9.3 yards per attempt (4,577 yards/491 attempts) last season — best in NFL; League Avg: 7.0.
Seattle Seahawks Offense: Important Stats
The Seahawks ran successful plays on 68% of plays against a light rush last season — best in NFL; League Avg: 39%.
The Seahawks have 6 TDs that were 20+ yards this season — most in NFL.
The Seahawks ran successful plays on 71% of pass attempts against a light rush last season — best in NFL; League Avg: 40%.
The Seahawks averaged 0.63 epa per play against a light rush last season — best in NFL; League Avg: -0.04.
San Francisco 49ers Defense: Important Stats
The 49ers defense allowed 11 broken tackles in Week 5 — most in NFL.
The 49ers defense allowed -0.56 epa per play with a light rush last season — 2nd-best in NFL; League Avg: -0.04.
The 49ers defense has allowed a third down conversion rate of 50% with a light front since the 2023 season — worst in NFL; League Avg: 31%.
The 49ers defense allowed successful plays on 10% of plays with a light rush last season — best in NFL; League Avg: 39%.
Seattle Seahawks Defense: Important Stats
The Seahawks defense has allowed successful plays on 12% of pass attempts with a light front this season — best in NFL; League Avg: 41%.
The Seahawks defense forced three and outs on 2% of opponent drives in the 4th quarter last season — worst in NFL; League Avg: 17%.
The Seahawks defense allowed 3 TD passes in close and late situations last season — T-most in NFL.
The Seahawks defense forced three and outs on 7% of opponent drives in the 2nd half last season — worst in NFL; League Avg: 20%.
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More NFL Betting Predictions:
- Anytime & First Touchdown Scorer Predictions
- Receiving Yards Prop Predictions
- Rushing Yards Prop Predictions
- Passing Yards Prop Predictions
- Receptions Made Prop Predictions
- Rushing Attempts Prop Predictions
- Passing Touchdowns Prop Predictions
- QB Interception Prop Predictions
- Field Goals Made Prop Predictions
- NFL Betting Previews: Every Game
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